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Topic: Endothelial tissue


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  MECHANISMS OF THROMBOSIS OF THE ANTIPHOSPHOLIPID ANTIBODIES   (Site not responding. Last check: 2007-11-05)
Tissue factor is a single chain transmembrane protein that is widely accepted to be a major physiological initiator of blood coagulation in vitro.
Induced tissue factor forms a tissue factor/activated factor VII complex in the presence of phospholipids and activates rapidly factors IX and X. The tissue factor pathway is modulated by the tissue factor pathway inhibitor.
These manifestations of endothelial cell dysfunction have been found in association with antibodies directed against endothelial cells, or with the presence of immune complexes, thus suggesting that endothelial cells are important sites of action for antibodies that have a role in the pathogenesis of thrombosis.
www.rheuma21st.com /archives/cutting_edge_22nov2004.html   (3140 words)

  
 Human adipose tissue endothelial cells promote preadipocyte proliferation -- Hutley et al. 281 (5): 1037 -- AJP - ...
with the organ-specific characteristics of endothelial cells (11).
This is not altogether surprising, because microvascular endothelial
Conditioned medium from primary porcine endothelial cells alone promotes the growth of primitive human haematopoietic progenitor cells with a high replating potential: evidence for a novel early haematopoietic activity.
ajpendo.physiology.org /cgi/content/full/281/5/E1037   (4713 words)

  
 Research
When activated (inflamed), they change their behavior to become pro-coagulant, and to encourage the adhesion and transit of white blood cells, whose job it is to penetrate the endothelial layer and deal with the troubled (infected, necrotic, etc.) underlying tissue.
It is a member of the immunoglobulin-like superfamily of integrins, and is known to be upregulated on the endothelial cell surface during inflammation.
Glass coverslips with monolayers of cultured endothelial cells are mounted in the chambers, and fluid (containing microbubbles) is flowed (perfused) across the cells under well-defined and controllable flow conditions.
www.geocities.com /drdrgreg/research.htm   (727 words)

  
 SIU SOM Histology CRR
Capillary endothelial nuclei are commonly difficult to distinguish from fibroblasts and other connective tissue cells, unless the preparation is fine enough to resolve the thin endothelial cytoplasm surrounding a small lumen.
Lymphoid tissue occurs in lamina propria of most mucosal organs, conspicuously in the gastrointestinal tract, where it is sometimes referred to as MALT, for Mucosa-Associated Lymphoid Tissue.
The connective tissue around a lymph nodule is usually heavily infiltrated with lymphocytes migrating to and from the germinal center.
www.siumed.edu /~dking2/crr/cvguide.htm   (3041 words)

  
 Lung uptake of antibodies to endothelial antigens: key determinants of vascular immunotargeting -- Danilov et al. 280 ...
In contrast, endothelial cells of arteries (large arrow), veins, and cortical capillaries were negative or faintly labeled.
Endothelial cells of lung tissue were homogeneously and strongly labeled by the MAb to ACE, encompassing those of pulmonary arteries (arrowhead) and alveolar capillaries.
PECAM-1 was expressed by endothelial cells of the pulmonary artery (arrowhead) and alveolar capillaries (inset), although intensity of expression appears to be weaker in the latter.
ajplung.physiology.org /cgi/content/full/280/6/L1335   (7975 words)

  
 Endothelial cell culture: beginnings of modern vascular biology -- Nachman and Jaffe 114 (8): 1037 -- Journal of ...
The endothelial cell as the maestro of thromboregulation.
Subtractive proteomic mapping of the endothelial surface in lung and solid tumors for tissue specific therapy.
Endothelial cells stimulate self-renewal and expand neurogenesis of neural stem cells.
www.jci.org /cgi/content/full/114/8/1037   (2216 words)

  
 Heparin/heparan sulfate chelation inhibits control of vascular repair by tissue-engineered endothelial cells -- Han et ...
100 µg/ml protamine in the absence of endothelial cell-conditioned
Endothelial denudation of rat common carotid arteries was performed with a 2-Fr Fogarty catheter.
Endothelial regeneration in the rat carotid artery and significance of endothelial denudation in the pathogenesis of myointimal thickening.
ajpheart.physiology.org /cgi/content/full/273/6/H2586   (5085 words)

  
 Modulation of endothelial cell activation in sickle cell disease: a pilot study -- Solovey et al. 97 (7): 1937 -- Blood   (Site not responding. Last check: 2007-11-05)
Tissue factor expression by endothelial cells in sickle cell anemia.
Endothelial cells in physiology and in the pathophysiology of vascular disorders.
Endothelial cell expression of tissue factor in sickle mice is augmented by hypoxia/reoxygenation and inhibited by lovastatin
www.bloodjournal.org /cgi/content/full/97/7/1937   (4085 words)

  
 Vidyya Medical News Service   - Today in Vidyya   
To assess corneal endothelial cell density as an indicator of the health of the cornea and as a surrogate outcome measure (in an optional ancillary study).
However, the weight of current evidence suggests that transplants using older donor tissue have similar success rates to those using younger donor tissue when endothelial cell counts of the donor tissue are comparable.
In other parts of the world, this bias against older donor tissue does not exist and donor age is not considered an important factor in assigning corneal tissue to a recipient.
www.vidyya.com /vol6/v6i140_2.htm   (799 words)

  
 Expression and Tissue Concentration of Vascular Endothelial Growth Factor, Its Receptors, and Localization in the ...
Tissue concentrations of VEGF protein (ng/g wet weight) in bovine CL during different luteal phases and pregnancy as measured by RIA.
Vascular endothelial growth factor is the major angiogenic factor in omentum: mechanism of the omentum-mediated angiogenesis.
Vascular permeability factor/vascular endothelial growth factor and the significance of microvascular hyperpermeability in angiogenesis.
www.biolreprod.org /cgi/content/full/63/4/1106   (5308 words)

  
 Plasticity of Human Adipose Lineage Cells Toward Endothelial Cells: Physiological and Therapeutic Perspectives -- ...
of adipose tissue as a metabolic and endocrine tissue.
In vitro differentiation of endothelial cells from AC133-positive progenitor cells.
Peripheral blood "endothelial progenitor cells" are derived from monocyte/macrophages and secrete angiogenic growth factors.
circ.ahajournals.org /cgi/content/full/109/5/656   (3867 words)

  
 Vascular Endothelial Growth Factor and Soft Tissue Sarcomas: Tumor Expression Correlates With Grade -- Chao et al. 8 ...
Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer.
Vascular endothelial growth factor expression in untreated osteosarcoma is predictive of pulmonary metastasis and poor prognosis.
Angiogenesis in carcinosarcomas of the uterus: difference in the microvessel density and expression of vascular endothelial growth factor between the epithelial and mesenchymal elements.
www.annalssurgicaloncology.org /cgi/content/full/8/3/260   (2655 words)

  
 Inhibition of Endothelial Cell Thromboresistance by Homocysteine -- Ling and Hajjar 130 (2): 373 -- Journal of Nutrition   (Site not responding. Last check: 2007-11-05)
Left panel: annexin II is expressed on endothelial cells as a peripheral membrane protein that binds plasminogen (PLG) via its core domain.
Hajjar K. Homocysteine-induced modulation of tissue plasminogen activator to its endothelial cell membrane receptor.
Hajjar K. A., Jacovina A. T., Chacko J. An endothelial cell receptor for plasminogen and tissue plasminogen activator: I. Identity with annexin II.
www.nutrition.org /cgi/content/full/130/2/373S   (2129 words)

  
 Atsushi Asakura, Ph.D. - Division of Cardiology in the Department of Medicine at the University of Minnesota   (Site not responding. Last check: 2007-11-05)
These results strongly suggest that residential endothelial progenitor cells detected in SP cells that exclude Hoechst dye may commonly reside in many adult tissues.
Furthermore, we will use tissue-derived endothelial progenitor cells for therapeutic purposes: We will test whether tissue-derived progenitor cells are capable of differentiation into cardiomyogenic and angiogenic cells and thus capable of restoring cardiac muscle and the needed vasculature to the injured heart following myocardial infarction.
Side population cells from diverse adult tissues are capable of in vitro hematopoietic differentiation.
www.med.umn.edu /cadiology/faculty/asakura.html   (799 words)

  
 Targeting endothelium and its dynamic caveolae for tissue-specific transcytosis in vivo: A pathway to overcome cell ...
cells to the underlying interstitium and tissue cells (8, 11).
tissues and enriched in lung P relative to the tissue homogenates
Note the evident tissue damage with gross change in tissue morphology, infiltration of blood cells into tissue, edema, and septal thickening.
www.pnas.org /cgi/content/full/99/4/1996   (4859 words)

  
 Tissue-specific distributions of alternatively spliced human PECAM-1 isoforms -- Wang et al. 284 (3): 1008 -- AJP - ...
Platelet endothelial cell adhesion molecule-1 (PECAM-1) is a cell adhesion molecule that is highly expressed on the surface
tissue and endothelial cells is absent in murine endothelium.
Platelet endothelial cell adhesion molecule-1 (PECAM-1) homophilic adhesion is mediated by immunoglobulin-like domains 1 and 2 and depends on the cytoplasmic domain and the level of surface expression.
ajpheart.physiology.org /cgi/content/full/284/3/H1008   (4779 words)

  
 Stretch-Induced Injury of Cultured Neuronal, Glial, and Endothelial Cells : Effect of Polyethylene Glycol—Conjugated ...
Endothelial cells growing on silastic membranes in the wells of flex plates were stretched to various extents and examined at increasing time intervals after injury (immediately [T
Also, endothelial cells more rapidly regained their capacity to exclude dye such that significant dye exclusion was apparent by 2 hours after injury.
Rabbit aortic endothelial cell hypoxia induces secretion of transforming growth factor beta and augments macrophage adhesion in vitro.
stroke.ahajournals.org /cgi/content/full/27/5/934   (4777 words)

  
 In Situ Detection of Tissue Factor within the Coronary Intima in Rat Cardiac Allograft Vasculopathy -- ...
Labarrere CA, Pitts D, Halbrook H, Faulk WP: Tissue plasminogen activator, plasminogen activator inhibitor-1, and fibrin as indexes of clinical course in cardiac allograft recipients: an immunocytochemical study.
Contrino J, Hair G, Kreutzer DL, Rickles FR: In situ detection of tissue factor in vascular endothelial cells: correlation with the malignant phenotype of human breast disease.
The role of vitronectin receptor ({alpha}v{beta}3) and tissue factor in the pathogenesis of transplant coronary vasculopathy
ajp.amjpathol.org /cgi/content/full/154/1/211   (5284 words)

  
 Corethics.org   (Site not responding. Last check: 2007-11-05)
Scientists in Germany have succeeded in coaxing adult stem cells to differentiate into endothelial tissue.
Endothelial tissue is crucial in the formation of new blood capillaries.
Using a similar technique the American team harvested stem cells from the blood and trained to develop into endothelial tissue.
www.corethics.org /document.asp?id=n260704.txt&se=4&st=6   (291 words)

  
 Pharyngula::Tyrannosaur morsels
Here, for example, is a piece of endothelial tissue, or the tubelike epithelia that line blood vessels and form capillaries.
If the tissues are as well preserved as they seem, the scientists held out some hope of recovering intact proteins, which are less fragile and more abundant DNA.
I don't regard it as axiomatic that tissues can't be semi-preserved for a long, long, time - dried-out ancient bacteria seem to be discovered all the time these days - but it is amazing.
pharyngula.org /index/weblog/comments/tyrannosaur_morsels   (1973 words)

  
 The expression of endothelial tissue plasminogen activator in vivo: a function defined by vessel size and anatomic ...
The expression of endothelial tissue plasminogen activator in vivo: a function defined by vessel size and anatomic location -- Levin et al.
The expression of endothelial tissue plasminogen activator in vivo: a function defined by vessel size and anatomic location
by all endothelial cells of the vascular system is invalid.
jcs.biologists.org /cgi/content/abstract/110/2/139   (759 words)

  
 Interstitial Vascularity in Fibrosing Alveolitis -- Renzoni et al. 167 (3): 438 -- American Journal of Respiratory and ...
Endothelial cell proliferation and vascular distribution in lung biopsies from control patients (A) and from patients with FASSc (B) and (C).
from the presence of foci of endothelial proliferation.
The paucity of endothelial cell proliferative foci in CFA in
ajrccm.atsjournals.org /cgi/content/full/167/3/438   (3468 words)

  
 Dr. Clauss' publications
The effect of hypoxia on capillary endothelial cell function: modulation of barrier and coagulant function.
Murray JC, Clauss M, Denekamp J, Stern D (1991) Selective induction of endothelial cell tissue factor in the presence of a tumour-derived mediator: A potential mechanism of flavone acetic acid action in tumour vasculature.
Clauss M, Grell M, Fangman C, Fiers W, Scheurich P, Risau W (1996) Synergistic induction of endothelial tissue factor by tumor necrosis factor and vascular endothelial growth factor: functional analysis of the tumor necrosis factor receptors.
www.iupui.edu /~icvbm/people/publications/clauss.html   (1556 words)

  
 Adipose tissue angiogenesis -- Hausman and Richardson 82 (3): 925 -- Journal of Animal Science
Adipose tissue angiogenesis -- Hausman and Richardson 82 (3): 925 -- Journal of Animal Science
of adipose tissue vasculature is discussed with respect to regulating
insulin and hypoxia, and is associated with adipose tissue accretion.
jas.fass.org /cgi/content/abstract/82/3/925   (326 words)

  
 Integral Role of RhoA Activation in Monocyte Adhesion-Triggered Tissue Factor Expression in Endothelial Cells -- ...
Integral Role of RhoA Activation in Monocyte Adhesion-Triggered Tissue Factor Expression in Endothelial Cells -- Ishibashi et al.
Integral Role of RhoA Activation in Monocyte Adhesion–Triggered Tissue Factor Expression in Endothelial Cells
indicated that the increase in endothelial expression of the
atvb.ahajournals.org /cgi/content/abstract/23/4/681   (538 words)

  
 Nitric oxide synthase gene transfer inhibits biological features of bypass graft disease in the human saphenous vein -- ...
and 90% ± 5% in uninfected tissue (P <.05).
platelet adhesion to human saphenous vein tissue was inhibited
was reduced in segments infected with endothelial nitric oxide
jtcs.ctsnetjournals.org /cgi/content/abstract/127/1/20   (347 words)

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