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Topic: Eosinophil

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In the News (Wed 19 Jun 19)

 Encyclopedia: Eosinophil granulocyte
Eosinophils also play a role in the allergic response, and in fibrin removal in inflammation.
Eosinophils are considered the main effector cells in asthma pathogenesis and are associated with disease severity.
The intestine is the portion of the alimentary canal extending from the stomach to the anus and, in humans and mammals, consists of two segments, the small intestine and the large intestine.
www.nationmaster.com /encyclopedia/Eosinophil-granulocyte   (1952 words)

 MedlinePlus Medical Encyclopedia: Eosinophil count - absolute
This is a test to measure the number of eosinophils (a type of white blood cell) in the blood.
The percentage of eosinophils is multiplied by the white blood cell count to give the absolute eosinophil count.
Eosinophils are white blood cells active in allergic diseases, parasitic infections, and other disorders.
www.nlm.nih.gov /medlineplus/ency/article/003649.htm   (690 words)

 Pharmacology of the Eosinophil -- Giembycz and Lindsay 51 (2): 213 -- Pharmacological Reviews   (Site not responding. Last check: 2007-10-20)
marker of the eosinophil is the appearance of granules that are
In the guinea pig, IL-5 releases eosinophils from the bone marrow by a mechanism that is blocked by the phosphatidylinositol
CC chemokines induce eosinophil chemotaxis and increase the intracellular free Ca concentration and actin polymerization that is associated with
pharmrev.aspetjournals.org /cgi/content/full/51/2/213   (5736 words)

 VCAM-1 is more effective than MAdCAM-1 in supporting eosinophil rolling under conditions of shear flow -- Sriramarao et ...
The number of detached eosinophils is expressed as a percentage of the total number of eosinophils adherent to VCAM-1 before stepwise increases in shear stress were applied to the coverslip in the flow chamber.
eosinophils was observed to be 0.26 ± 0.07 mm/sec.
Endothelial leukocyte adhesion molecule-1 and intercellular adhesion molecule-1 mediate the adhesion of eosinophils to endothelial cells in vitro and are expressed by endothelium in allergic cutaneous inflammation in vivo.
www.bloodjournal.org /cgi/content/full/95/2/592   (6947 words)

 LPS Induces Eosinophil Migration via CCR3 Signaling Through a Mechanism Independent of RANTES and Eotaxin -- Penido et ...
the accumulation of eosinophils induced by eotaxin in vivo (16).
Endotoxin induces eosinophil accumulation in the rat pleural cavity.
Eosinophil recruitment to the lung in a murine model of allergic inflammation: the role of T cells, chemokines, and adhesion receptors.
ajrcmb.atsjournals.org /cgi/content/full/25/6/707   (5900 words)

 HON Allergy Glossary Eosinophil
Eosinophil secretory products inactivate many of the chemical mediators of inflammation and destroy cancer cells.
Produced in the bone marrow, eosinophils then migrate to tissues throughout the body.
When a foreign substance enters the body, lymphocytes and neutrophils release certain substances to attract eosinophils which release toxic substances to kill the invader.
www.hon.ch /Library/Theme/Allergy/Glossary/eosinophil.html   (103 words)

 Perturbations in Eosinophil Homeostasis following Treatment of Lymphatic Filariasis -- Gopinath et al. 68 (1): 93 -- ...   (Site not responding. Last check: 2007-10-20)
Eosinophil counts expressed as the GM (A), plasma IL-5 levels (B), and RANTES levels (C) in study patients as a function of hours posttreatment (horizontal axes) are shown as hatched bars, while corresponding levels in controls are shown as solid bars.
Eosinophil degranulation, the release of toxic cationic proteins from secondary granules within the cell, is one of the major
The eosinophil granule proteins in serum, but not the oxidative metabolism of the blood eosinophils, are increased in cancer.
iai.asm.org /cgi/content/full/68/1/93   (4626 words)

 Cultured Human Airway Smooth Muscle Cells Stimulated by Interleukin-1beta Enhance Eosinophil Survival -- Hallsworth et ...
Eosinophils cultured in medium alone (open bar) or in the presence of 1 ng/ml rhGM-CSF (filled bar) were used as negative and positive controls, respectively, for eosinophil survival.
In the blood, eosinophils are short-lived with a half-life of 18 h (35).
Eosinophil apoptosis and the resolution of airway inflammation in asthma.
ajrcmb.atsjournals.org /cgi/content/full/19/6/910   (5962 words)

 Regulation of Human Eosinophil Migration Across Lung Epithelial Monolayers by Distinct Calcium Signaling Mechanisms in ...
Effect of extracellular Ca on eosinophil transmigration across H292 epithelial cell monolayers (A) and eosinophil migration in the Boyden chamber chemotaxis assay in the absence of epithelial cells (B).
BAPTA/AM and that eosinophil migration in the Boyden chamber
Eosinophil peroxidase stimulates the release of granulocyte-macrophage colony-stimulating factor from bronchial epithelial cells.
www.jimmunol.org /cgi/content/full/163/10/5649   (4838 words)

 Eosinophil activation and preschool viral wheeze -- Oommen et al. 58 (10): 876 -- Thorax
Eosinophil cationic protein (ECP) and eosinophil protein X (EPX) concentrations in serum and bronchial lavage fluid in asthma.
Urinary eosinophil protein X and serum eosinophil cationic protein in infants and young children with atopic dermatitis: correlation with disease activity.
Urinary leukotriene E(4), eosinophil protein X, and nasal eosinophil cationic protein are not associated with respiratory symptoms in 1-year-old children.
thorax.bmjjournals.com /cgi/content/full/58/10/876   (2453 words)

 Eosinophil Count
Decreased eosinophils occurs in adrenal cortical hyperplasia (Cushing syndrome), cortisone therapy, hormone-secreting tumors, intermenstrual period, acute and chronic inflammation, and anoxia.
Toxocaral disease (visceral larva migrans) is a typical parasitic disease in which eosinophil counts (eosinophils >30% on differential) are usually elevated.
An important although rare cause of increased eosinophils in the peripheral blood is the acute hypereosinophilic syndrome (HES).
www.labcorp.com /datasets/labcorp/html/chapter/mono/he001900.htm   (537 words)

 Antagonism between C/EBPbeta and FOG in eosinophil lineage commitment of multipotent hematopoietic progenitors -- ...
Antagonism between C/EBPbeta and FOG in eosinophil lineage commitment of multipotent hematopoietic progenitors -- Querfurth et al.
, and Mim-1, all markers of the eosinophil lineage.
of GATA-1 (in eosinophils) or FOG (in FOG-expressing myeloblasts),
www.genesdev.org /cgi/content/full/14/19/2515   (6618 words)

 Effects of Budesonide and Formoterol on Eosinophil Activation Induced by Human Lung Fibroblasts -- SPOELSTRA et al. 162 ...
Eosinophils are thought to be the most important effector cells in asthma.
Immunophenotyping of eosinophils recovered from blood and BAL of allergic asthmatics.
Eosinophil locomotion and the release of IL-3 and IL-5 by allergen-stimulated mononuclear cells are effectively downregulated in vitro by budesonide.
ajrccm.atsjournals.org /cgi/content/full/162/4/1229   (3366 words)

 Kinetics of Eotaxin Generation and Its Relationship to Eosinophil Accumulation in Allergic Airways Disease: Analysis in ...
Eosinophil numbers in lung tissue were quantitated as previously described (27).
Eosinophils, harvested from the peritoneal cavity of female exbreeder guinea pigs (800-900 g) given repeated i.p.
Eosinophils, T-lymphocytes, mast cells, neutrophils, and macrophages in bronchial biopsy specimens from atopic subjects with asthma: comparison with biopsy specimens from atopic subjects without asthma and normal control subjects and relationship to bronchial hyperresponsiveness.
www.jem.org /cgi/content/full/186/4/601   (6605 words)

 British Journal of Pharmacology - Abstract of article: Nitric oxide regulates human eosinophil adhesion mechanisms in ...
Human peripheral blood eosinophils were treated with L-NAME (0.01 − 1.0 mM) and their adhesion to human fibronectin and serum observed.
This inhibition was accompanied by a 4 fold increase in the levels of intracellular cyclic GMP.
This inhibition is accompanied by a decrease in the expression and function of the eosinophil's adhesion molecules, in particular, the expression of the Mac-1 integrin and the function of the VLA-4 integrin.
www.nature.com /bjp/journal/v134/n3/abs/0704295a.html   (400 words)

 Essential and Instructive Roles of GATA Factors in Eosinophil Development -- Hirasawa et al. 195 (11): 1379 -- The ...   (Site not responding. Last check: 2007-10-20)
Eosinophil colonies were generated from bone marrow cells of transgenic mice bearing IE3.9int-directed GFP in the presence of IL-5 alone.
The eosinophil colony was lifted and cytocentrifuged onto a glass slide, then stained by May-Grüenwald Giemsa staining (middle) and Fast green staining (right).
eosinophil development in vivo remains to be determined.
www.jem.org /cgi/content/full/195/11/1379   (3963 words)

 Eosinophil-Associated Inflammation and Elaboration of Eosinophil-Derived Proteins in 2 Children With Raccoon Roundworm ...   (Site not responding. Last check: 2007-10-20)
Fox AS, Kazacos KR, Gould NS, Heydemann PT, Thomas C, Boyer KM Fatal eosinophilic meningoencephalitis and visceral larva migrans caused by the raccoon ascarid Baylisascaris procyonis.
Miyashita M. Prevalence of Baylisascaris procyonis in raccoons in Japan and experimental infections of the worm to laboratory animals.
Wang JM, Rambaldi A, Biondi A, Chen AG, Sanderson CJ, Mantovani A Recombinant human interleukin 5 is a selective eosinophil chemoattractant.
pediatrics.aappublications.org /cgi/content/full/108/5/e93   (2971 words)

 Chemokine-induced Eosinophil Recruitment . Evidence of a Role for Endogenous Eotaxin In An In Vivo Allergy Model in ...
Selective eosinophil recruitment into tissues is a characteristic feature of allergic diseases.
In-eosinophil recruitment was also observed in an active cutaneous
CCR3 with mEotaxin, or blockade of the receptor with metRANTES,
www.jci.org /cgi/content/abstract/100/7/1657   (1861 words)

 Deletion of the major GATA1 enhancer HS 1 does not affect eosinophil GATA1 expression and eosinophil differentiation -- ...
from eosinophils and encompassing HS 1 is weakly enriched for
and eosinophil differentiation are unaffected in absence of
HS 1 is not required for eosinophil GATA1 expression and eosinophil maturation.
www.bloodjournal.org /cgi/content/full/104/1/89   (2194 words)

 Variations in Eosinophil Chemokine Responses: An Investigation of CCR1 and CCR3 Function, Expression in Atopy, and ...
Variations in Eosinophil Chemokine Responses: An Investigation of CCR1 and CCR3 Function, Expression in Atopy, and Identification of a Functional CCR1 Promoter -- Phillips et al.
Variations in Eosinophil Chemokine Responses: An Investigation of CCR1 and CCR3 Function, Expression in Atopy, and Identification of a Functional CCR1 Promoter
expression of CCR1 and CCR3 on eosinophils, basophils, monocytes,
www.jimmunol.org /cgi/content/abstract/170/12/6190   (416 words)

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