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Topic: Ependymoma


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In the News (Sun 27 Dec 09)

  
  Ependymoma - My Child Has - Children's Hospital Boston   (Site not responding. Last check: 2007-10-20)
An ependymoma is a tumor that arises from cells of the ependymal lining of the ventricular system of brain or spinal cord.
Ependymomas account for 25 percent of all spinal cord tumors.
Ependymoma of the brain treated with complete resection and radiation to the tumor area can result in an approximately 50 percent cure rate.
www.childrenshospital.org /az/Site841/mainpageS841P0.html   (1087 words)

  
 Ependymoma - Wikipedia, the free encyclopedia
Ependymoma are tumors arising from the inner lining of the cerebral ventricles (= intracranial) and the remnants of the central canal in the spinal cord.
The common location of intracranial ependymomas is the fourth ventricle.
Ependymomas are also seen with Neurofibromatosis Type II.
en.wikipedia.org /wiki/Ependymoma   (79 words)

  
 AANS.org | Education and Meetings | AANS Scientific Journals | Neurosurgical Focus
In summary, a diagnosis of ependymoma may be claimed when the tumor is located in the center of the spinal cord, when contrast enhancement is homogeneous, when the margins of the tumor are clearly defined, and when a "cap" sign is observed at both poles of the solid portion.
In 20% of ependymomas and in 24% of astrocytomas, we observed no contrast enhancement: this is the reason that, except in the four conditions just described, we think that diagnostic MR imaging may be misleading with potentially hazardous ramifications.
Their experience is based on a series of 12 ependymomas and 11 astrocytomas of all grades, and they reported eight failures (four ependymomas and four astrocytomas): recurrence with death in five cases.
www.aans.org /education/journal/neurosurgical/may98/4-5-2.asp?ShowMenu=false&ShowPrint=false   (3355 words)

  
 Ependymoma : Cancerbackup
Ependymomas may spread from the brain to the spinal cord in the cerebrospinal fluid (CSF).
Ependymomas can grow in different parts of the brain, and symptoms may relate to the area of the brain that is affected.
As ependymomas may spread to the spinal cord, radiotherapy may be given to both the brain and spinal cord.
www.cancerbackup.org.uk /Cancertype/Brain/Typesofbraintumour/Ependymoma   (1615 words)

  
 Adult Ependymoma: a Patient's Story   (Site not responding. Last check: 2007-10-20)
Ependymomas are glial tumors which arise from ependymal cells which line the ventricles (spinal fluid spaces) of the brain and the center of the spinal cord.
Ependymomas are tumors and they can recur either locally in the brain or into the spinal cord, so in that sense they are cancerous.
Most importantly, and frighteningly, ependymomas, even if benign on the WHO scale, can be deadly simply by their location, either if they grow and cause death or if they are removed and cause death from the surgery.
home.earthlink.net /~mswelsh/adultependymoma   (1504 words)

  
 Ependymoma
Ependymomas are glial neoplasms whose clinical behavior is difficult to predict based on histology alone.
Ependymomas are common pediatric and adult CNS malignancies with a wide biologic spectrum that is often hard to predict using classic prognostic variables.
Classic and anaplastic ependymomas with gain of 1q tended to occur in the posterior fossa of children and to behave aggressively.
www.thedoctorsdoctor.com /diseases/ependymoma.htm   (7736 words)

  
 Childhood Ependymoma:   (Site not responding. Last check: 2007-10-20)
Children with ependymoma should have their treatment planned by a team of doctors with expertise in treating childhood brain tumors.
Childhood ependymoma is a disease in which malignant (cancer) cells form in the tissues of the brain and spinal cord.
For childhood ependymoma, tumors are described by grade and by where they are located in the central nervous system (brain and spinal cord).
www.acor.org /cnet/62971.html   (2516 words)

  
 Ependymoma, childhood: Treatment - Patient Information [NCI PDQ] - Quest Diagnostics Patient Health Library   (Site not responding. Last check: 2007-10-20)
Childhood ependymoma is a disease in which malignant (cancer) cells form in the tissues of the brain and spinal cord.
The symptoms of childhood ependymoma vary and often depend on the child’s age and where the tumor is located.
Damage to the brain in young children treated for ependymoma is not always due to the effects of radiation therapy.
www.questdiagnostics.com /kbase/nci/ncicdr0000062971.htm   (2649 words)

  
 Best Cases from the AFIP: Supratentorial Ependymoma -- Mermuys et al. 25 (2): 486 -- RadioGraphics
Intracranial ependymomas of childhood: long-term outcome and prognostic factors.
The prognostic significance of postoperative residual tumor in ependymoma.
Ependymoma diagnosed in the first year of life in Japan in collaboration with the International Society for Pediatric Neurosurgery.
radiographics.rsnajnls.org /cgi/content/full/25/2/486   (1689 words)

  
 CIGNA - Ependymoma, childhood: Treatment - Health Professional Information [NCI PDQ]   (Site not responding. Last check: 2007-10-20)
The most recent World Health Organization classification of brain tumors maintains the term “ependymoma” for tumors that are histologically benign and malignant ependymoma for those that have malignant characteristics.[3] These categories are based on the nuclear/cytoplasmic ratio, number of nuclei and mitotic figures, and the degree of nuclear atypia.
Thirty percent of childhood ependymomas arise outside of the posterior fossa.[1,2,3] Every patient with ependymoma should be evaluated with diagnostic imaging of the spinal cord and whole brain.
For ependymoma, delays beyond 10 to 15 years have been reported.[1,2] Disease generally recurs at the primary tumor site, even in children with malignant ependymomas.[3,4] Systemic relapse is extremely rare.
www.cigna.com /healthinfo/ncicdr0000062843.html   (3735 words)

  
 [No title]   (Site not responding. Last check: 2007-10-20)
In contrast to myxopapillary ependymoma that adapt a papillary growth pattern, cells in chordoma arrange in chords and are embedded in the myxoid matrix.
Myxopapillary ependymoma of the filum terminale and cauda equina in childhood: report of seven cases and review of the literature.
Clonal telomeric fusions and chromosome instability in a subcutaneous sacrococcygeal myxopapillary ependymoma.
moon.ouhsc.edu /kfung/JTY1/Com04/Com411-3-Diss.htm   (1922 words)

  
 eMedicine - Ependymoma : Article by Tobey MacDonald, MD
Approximately one third of ependymomas are supratentorial, arising from the surface of the lateral or third ventricles; however, they may be entirely extraventricular.
Ependymoma is often overlooked because signs and symptoms of increased ICP are typically subacute, nonspecific, and nonlocalizing.
Shuman RM, Alvord EC Jr, Leech RW: The biology of childhood ependymomas.
www.emedicine.com /ped/topic693.htm   (4486 words)

  
 Childhood ependymoma : 08627   (Site not responding. Last check: 2007-10-20)
Approximately 10% of all childhood brain tumors are ependymomas.
Your child's treatment and chance of recovery (prognosis) depend on the type and size of tumor, where it is located within the brain, and his or her age and general health.
If the ependymoma is in a place where it cannot be removed, surgery may be limited to a biopsy of the cancer.
www.acor.org /cnet/208627.html   (1877 words)

  
 Ependymoma
If you have a better definition for Ependymoma than the one presented here, please let us know by making use of the suggest a term option.
This definition of Ependymoma may be disputed by other professionals.
Our attempt is to provide easy definitions on Ependymoma and any other medical topic for the public at large.
www.healthdictionary.info /Ependymoma.htm   (579 words)

  
 Bioline International Official Site (site up-dated regularly)
Ependymoma is a slow growing glial tumor originating from the ventricular lining or central canal and is composed of neoplastic ependymal cells.
While the issue of radiotherapy in ependymomas in children is still not completely settled, it is generally advised to give radiotherapy even after complete removal.
Ependymomas occurring supratentorially without any connection to the ventricular system are rare.
www.bioline.org.br /request?ni06111   (765 words)

  
 Ependymoma, childhood: Treatment - Patient Information [NCI PDQ] This information is produced and, Eastern North ...   (Site not responding. Last check: 2007-10-20)
Ependymoma, childhood: Treatment - Patient Information [NCI PDQ] This information is produced and, Eastern North Carolina, NC To search for a specific phrase enclose that phrase in quotes.
Recurrent childhood ependymoma is a tumor that has recurred (come back) after it has been treated.
After surgery, treatment depends on the age of the child, the amount of tumor that was removed, and whether cancer cells have spread to other parts of the central nervous system.
www.uhseast.com /112774.cfm   (2464 words)

  
 Reference.com/Encyclopedia/Ependymoma
Ependymoma are tumors arising from the inner lining of the cerebral ventricles (= intracranial) and the remnants of the central canal in the spinal cord.
The malignant (anaplastic) varieties of this tumor, malignant ependymoma and the ependymoblastoma, are treated similarly to medulloblastoma but the prognosis is much less favorable.
The subependymoma, a variant of the ependymoma, is apt to arise in the fourth ventricle but may occur in the septum pellucidum and the cervical spinal cord.
www.reference.com /browse/wiki/Ependymoma   (495 words)

  
 Nervous system: Ependymomas
Ependymomas account for 6 to 12 % of brain tumors in children and represent the third most common central nervous system neoplasms in this age range, following astrocytoma and medulloblastoma.
Clustering of ependymomas has been noted in some families suggesting inheritance of a genetic susceptibility to this type of tumor.
Monosomy 10 was reported in few cases of anaplastic ependymomas associated with LOH of 17p.
www.infobiogen.fr /services/chromcancer/Tumors/EpendymomID5016.html   (1121 words)

  
 [Metastasis of a lumbosacral ependymoma with very long disease-free survival: a case report and review of the literature   (Site not responding. Last check: 2007-10-20)
Ependymoma is rare glial tumour of the central nervous system and is considered to be low-grade.
Prognosis of ependymomas is dependent on tumour location, histological subtype and differentiation, extent of the tumour and of the completeness of the surgical resection.
Ependymomas are often recurrent at the primary site, but can seed on the entire cerebrospinal axis.
www.galenicom.com /medline/article/16581282/mt:Spinal%252520Cord%252520Neoplasms   (408 words)

  
 Childhood Ependymoma
Thirty percent of childhood ependymomas arise outside of the posterior fossa.
Korshunov A, Golanov A, Sycheva R, et al.: The histologic grade is a main prognostic factor for patients with intracranial ependymomas treated in the microneurosurgical era: an analysis of 258 patients.
There is evidence that surveillance neuroimaging in childhood ependymoma will identify tumors that have recurred when the patient is asymptomatic, however, it is unclear whether this detection will change the ultimate prognosis of the patient.
www.meb.uni-bonn.de /cancer.gov/CDR0000062843.html   (4106 words)

  
 Evidence for an ependymoma tumour suppressor gene in chromosome region 22pter22q11.2
Ependymomas are glial tumours of the brain and spinal cord.
The most frequent genetic change in sporadic ependymoma is monosomy 22, suggesting the presence of an ependymoma tumour suppressor gene on that chromosome.
Loss of heterozygosity studies in that tumour revealed that, in accordance to Knudson's two-hit theory of tumorigenesis, the lost chromosome 22 originated from the parent presumed to have contributed the wild-type allele of the susceptibility gene.
www.nature.com /bjc/journal/v81/n7/abs/6690822a.html   (279 words)

  
 Newswise
Brain tumors called ependymomas that occur in different parts of the central nervous system appear to arise from subpopulations of stem cells called radial glia cells (RGCs), according to investigators at St. Jude Children’s Research Hospital.
For example, although all ependymomas look alike, supratentorial ependymomas arise in the top part of the brain in both adults and children; often cause weakness in the arms and legs, visual problems and seizures; and have a survival rate of 50-60 percent.
Posterior fossa ependymomas arise in the back of the brain and cause patients to have an unsteady walk and neck pain; and they occur mainly in children and have a slightly worse prognosis than do surpratentorial tumors.
www.newswise.com /articles/view/515430   (981 words)

  
 Ependymoma of the fourth ventricle - MedPix™ Medical Image Database and Teaching Files
Ependymoma accounts for about 9% of childhood brain tumors and 5- 6% of all intracranial gliomas.
Ependymoma is hypo- to isointense on T1-weighted images and heterogeneously hyperintense on T2-weighted studies.
Ependymoma and medulloblastoma may be indistinguishable on CT or MR.
rad.usuhs.mil /medpix/master.php3?mode=single&recnum=1444&table=card&srchstr=&search=   (447 words)

  
 Parasagittal Ependymoma Resembling Falcine Meningioma -- Youkilis et al. 22 (6): 1105 -- American Journal of ...
The origin of such intraaxial ependymomas is controversial.
Intracerebral ependymomas represent 5% of all intracranial tumors
The etiology of extraaxial, supratentorial ependymomas is unclear.
www.ajnr.org /cgi/content/full/22/6/1105   (1351 words)

  
 Brain Cancer Childhood Ependymoma
Thirty percent of ependymomas arise outside of the posterior fossa.[1-3] Every patient with ependymoma should be evaluated with diagnostic imaging of the spinal cord and whole brain.
While a number of factors have sometimes been associated with an unfavorable outcome (younger age at diagnosis, lower doses of radiation, anaplastic histology, subtotal resection) [1,4-6], age and extent of resection have consistently been the most important factors.[5-7] These prognostic variables must be evaluated in the context of the treatment received.
Patients with recurrent ependymomas who have not previously received radiation therapy and/or chemotherapy, should be considered for treatment with these modalities.
www.medhelp.org /lib/cancernet/108627.htm   (2955 words)

  
 Association of lower cranial nerve schwannoma with spinal ependymoma in ? NF2. Kumar R, Sharma KH, Chhabra DK Neurol ...
According to Thapar et al,[1] in the absence of bilateral vestibular schwannomas, the diagnosis of NF 2 may be suspected in the children having meningiomas, schwannomas or with multiple heterogeneous lesions.
The diagnosis of cranial ependymoma was considered in view of already operated spinal ependymoma, with the presumption that either the cranial ependymoma did not manifest earlier (before the operation) because of its insignificant size or the diagnosis had been missed initially.
We strongly suspect the diagnosis of NF 2 in this case, as the association of lower cranial nerve schwannoma with spinal ependymoma, is one of its presentations.
www.neurologyindia.com /article.asp?issn=0028-3886;year=1999;volume=47;issue=2;spage=145;epage=7;aulast=Kumar   (1047 words)

  
 Ependymoma   (Site not responding. Last check: 2007-10-20)
Ependymoma accounts for 10% of all pediatric central nervous system tumors and originates in ventricular spaces or from residual intra-parenchymal ependymal cells.
Surgery should be therefore performed in one or more operations, according to the patient's neurological conditions, to decrease surgical morbidity, thereby increasing chances to implement subsequent treatment.
Radiotherapy allows controlling ependymoma; new radiotherapy treatment techniques, such as 3-D conformal radiotherapy, may enable the delivery of high radiation doses to small tumor volumes, improving the therapeutic ratio.
www.orpha.net /static/GB/ependymoma.html   (202 words)

  
 eMedicine - Ependymoma : Article by Subrata Ghosh, MD, MBBS, MS
Background: Ependymomas are neoplasms of ependymal cells that occur throughout the entire neuraxis in association with the lining of the cerebral ventricles and central canal of the spinal cord.
However, ependymomas are the third most common brain tumor in children (8-12%) with up to 30% occurring in children younger than 3 years.
Half of the ependymomas occur in the first 2 decades of life; two-thirds are located in the posterior fossa (>than 90% are in the fourth ventricle).
www.emedicine.com /neuro/topic126.htm   (1477 words)

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