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| | CIGNA - Ependymoma, childhood: Treatment - Health Professional Information [NCI PDQ] (Site not responding. Last check: 2007-10-20) |
 | | The most recent World Health Organization classification of brain tumors maintains the term “ependymoma” for tumors that are histologically benign and malignant ependymoma for those that have malignant characteristics.[3] These categories are based on the nuclear/cytoplasmic ratio, number of nuclei and mitotic figures, and the degree of nuclear atypia. |
 | | Thirty percent of childhood ependymomas arise outside of the posterior fossa.[1,2,3] Every patient with ependymoma should be evaluated with diagnostic imaging of the spinal cord and whole brain. |
 | | For ependymoma, delays beyond 10 to 15 years have been reported.[1,2] Disease generally recurs at the primary tumor site, even in children with malignant ependymomas.[3,4] Systemic relapse is extremely rare. |
| www.cigna.com /healthinfo/ncicdr0000062843.html (3735 words) |
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