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Topic: Eric Lander


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  Biography: Eric Lander
Eric Lander is the Director of the Whitehead Institute/MIT Center for Genome Research, one of the ‘big three’ genome labs (with the Wellcome Trust Sanger Institute and the Genome Sequencing Center at Washington University in St Louis) that between them sequenced most of the human genome.
Lander first produced a very early genetic map of the whole human genome, showing the positions of around 400 markers – the signposts that geneticists use to locate disease genes on the chromosomes.
Lander has always maintained a commitment to activities outside the lab: he serves on numerous government advisory committees; is a founder and director of Millennium Pharmaceuticals, and has chaired the Joint Steering Committee for Public Policy which lobbies for government funding for basic biomedical research.
www.wellcome.ac.uk /en/genome/geneticsandsociety/hg13f027.html   (583 words)

  
 Encyclopedia: Eric Lander   (Site not responding. Last check: 2007-10-08)
Lander and his colleagues are hoping the LD map will allow them to test the Common Disease-Common Variant hypothesis which states than many common diseases may be caused by a small number of common alleles, for example 50% of the variance in susceptibility to Alzheimer's disease is explained by the common allele ApoE4.
Landers group have recently discovered an important association which accounts for a large proportion of population risk for adult onset diabetes.
Much of Lander's work is in genomics a field which involves large scale experiments huge groups of researchers collaborating thus it is difficult to single out one person and point to a given discovery or single career moment and say that this was the key.
www.nationmaster.com /encyclopedia/Eric-Lander   (1858 words)

  
 NOVA Online | Cracking the Code of Life | Dr. Eric Lander
Lander: The genome is, it's a fossil record; the genome is a landscape; the genome is a whole geography of distributions.
Lander: For Huntington's disease we know that the problem is the gene is defective in a way that it makes a protein that is a big long extra chunk of it that's very sticky, and it sticks to other stuff and gums up the works.
Lander: Oh, I think, about half of the common genetic variation that exists in the human population is already represented in that data base of DNA differences that we found amongst people.
www.pbs.org /wgbh/nova/genome/deco_lander.html   (13225 words)

  
 Eric S. Lander's "14-Year Digression" with the Human Genome
Lander of the Whitehead Institute, Cambridge, Massachusetts, have known the questions for 15 years and have spent much of the intervening time working on the sequence so that they could get their answers.
Lander, 45, received his bachelor's degree in mathematics from Princeton and was awarded a Rhodes Scholarship to Oxford University, where he received his doctorate in mathematics in 1981.
Lander is also professor of biology at the Massachusetts Institute of Technology and a scientific founder of Millennium Pharmaceuticals.
www.sciencewatch.com /march-april2002/sw_march-april2002_page3.htm   (905 words)

  
 CNN Specials - Blueprint of the Body: Eric Lander
Eric S. Lander is director of the Whitehead Institute/MIT Center for Genome Research in Cambridge, Massachusetts, which Lander describes as the flagship research center for the government's Human Genome Project.
LANDER: The human genome is a code, a code written into four letters A, T, C and G, standing for the building blocks of DNA, and all of the information is encoded into a string of three billion of these A, T, Cs and Gs.
LANDER: Only about 5 percent of the human DNA encodes the proteins, the other 95 percent encodes a variety of other stuff like the middles of your chromosomes that let them separate properly, it encodes selfish transposable elements that are just hopped around your DNA and probably don't do you any good at all.
www.cnn.com /SPECIALS/2000/genome/story/interviews/lander.html   (5577 words)

  
 KeepMedia | R & D: 2003 Scientist of the Year
Eric Steven Lander was educated as a mathematician, taught managerial economics at the Harvard School of Business for nine years, currently teaches undergraduate biology at MIT, and founded and now directs the world's preeminent Center for Genome Research at the Whitehead Institute.
Lander's leadership and technical involvement in the Human Genome Project led to the sequencing of nearly a third of the genome at the Whitehead Institute.
Lander's leadership in all things genomic have led to his recent selection as the Director of the Broad Institute, a collaboration of the Whitehead Institute, MIT, and several Harvard University-affiliated hospitals and funded with $100 million by philanthropists Eli and Edythe Broad.
keepmedia.com /pubs/RD/2003/11/01/322862?from=search&criteria=GENOME   (197 words)

  
 Broad Press Release - Eric Lander receives 2004 AAAS Public Understanding of Science & Technology Award
Lander, founding director of the newly created Broad Institute of MIT and Harvard "has helped to tell the stories of genomics research to a broad cross-section of the general public in a consistently compelling and meaningful way," said Shirley Malcom, director of Education and Human Resources at AAAS.
Lander was cited by AAAS "for his excellence in communicating complex scientific ideas, and their implications for society, to the general public and policymakers, while actively engaged in a demanding and aggressive research program."
Lander was elected a Member of the U.S. National Academy of Sciences in 1997 and the U.S. Institute of Medicine in 1999.
www.broad.mit.edu /media/2005/aaas-0218.html   (581 words)

  
 Whitehead Institute - Eric Lander Wins Gairdner Award
Lander and the other winners were recognized for their outstanding contributions in genomic research.
Lander helped develop cost-effective processes to map and sequence the human genome, creating world-class automation, robotics, and information technology to sequence nearly a third of all the sequence now available in public databases.
Lander is a member of the Whitehead Institute and the founder and director of the Whitehead Institute Center for Genome Research, one of the world’s leading genome centers.
www.wi.mit.edu /news/archives/2002/el_0425.html   (657 words)

  
 Whitehead Institute - Eric Lander
Lander was a world leader of the international Human Genome Project, the effort to map the blueprint for a human being.
Today, Lander is using the knowledge of the human genome to tackle the fundamental issue of medicine: to find the causes versus the symptoms of disease.
Lander’s group recently launched a revolution in the study of human genetic variation, through its own research, and participation in larger projects devoted to the question.
www.wi.mit.edu /research/faculty/lander.html   (584 words)

  
 UNESCO Arts, Science & Technology
Eric S. Lander is a geneticist, molecular biologist and a mathematician, with research interests in human genetics, mouse genetics, population genetics and computational and mathematical methods in biology.
Lander is a Member of the Whitehead Institute for Biomedical Research, Professor of Biology at the Massachusetts Institute of Technology and Director of the Whitehead Center for Genome Research.
Lander was awarded a Rhodes Scholarship in 1978, received the MacArthur Foundation Prize Fellowship in 1987 for his work in genetics.
digitalarts.lcc.gatech.edu /unesco/biotech/scientists/bio_s_elander.html   (249 words)

  
 Eric Lander -- Facts, Info, and Encyclopedia article   (Site not responding. Last check: 2007-10-08)
At the suggestion of his brother Adam Lander he started to look at neurobiology “because there's a lot of information in the brain”.
Lander then joined (1986) and later joined MIT as a geneticist.
W.I.C.G.R. is one of the worlds leading centres of genome research and under Doctor Lander’s leadership they have made great progress in developing new methods of analysing mammalian genomes.
www.absoluteastronomy.com /encyclopedia/e/er/eric_lander.htm   (1073 words)

  
 Eric Lander is among TIME's most influential - MIT News Office
Professor Eric Lander, founder and director of the Eli and Edythe L. Broad Institute, is featured as one of the world's 100 most influential people in the April 26 special issue of TIME magazine.
Lander is cited most recently as the visionary behind the creation of the Broad, which is harnessing the talents of MIT, Harvard and its hospitals, and the Whitehead Institute to tackle the big questions facing biomedical science today.
Lander is professor of biology at MIT, professor of systems biology at Harvard Medical School and a member of the Whitehead Institute.
web.mit.edu /newsoffice/2004/lander-0505.html   (330 words)

  
 NOVA | Transcripts | Cracking the Code of Life | PBS
ERIC LANDER: Whoever contributed this DNA, you can tell from this whether or not they might be at early risk for Alzheimer's disease, you can tell whether or not they might be at early risk for breast cancer.
ERIC LANDER: The laboratory was a laboratory in Buffalo.
ERIC LANDER: You have to worry a lot that this region here, that you're working on, that might cure cancer has already been patented by somebody else and that patent filing is not public.
www.pbs.org /wgbh/nova/transcripts/2809genome.html   (15430 words)

  
 Dalai Lama Visits Whitehead Genome Center
Lander, a self-proclaimed novice in both Buddhist tradition and the mind sciences, said that "commitment to openness" and common motivations "to strive to ameliorate suffering in the world," and "intellectual curiosity about the world" should be the foundation for more in-depth dialog and collaborative research.
Lander challenged that as investigators of the mind we need to be able to see that there are obtainable goals that lie somewhere in between western science's cognitive study of mental illness and the Buddhist adept's familiarity of something akin to an "Olympic status of mental health."
The Dalai Lama is assisted by Whitehead Institute/MIT Center for Genome Research Director Eric Lander (R) and Yama Chompel (L) as he prepares mouse DNA for sequencing with a syringe and pipette.
www-genome.wi.mit.edu /media/2003/pr_03_dalai.html   (688 words)

  
 Millenium Evening at the White House   (Site not responding. Last check: 2007-10-08)
DR. LANDER: Well, I think in a sense, the different communities and how they're going to be affected by this and what access they really have is much less with respect to genetics as a question of technology or infrastructure or cost than it is a question of understanding and education.
Eric mentioned a couple of diseases that we know are almost inevitable given a certain variation in the genetic code.
And I agree entirely with Eric, that we should think of insurance as a way of providing pooled protection for the population, and not a system that is based on a gaining that allows individuals to seek the genetic information and then provide special protection for themselves based on that information.
www.rand.org /scitech/stpi/ourfuture/Rosetta/millennium.html   (18539 words)

  
 TIME Magazine: TIME 100: Eric Lander   (Site not responding. Last check: 2007-10-08)
It was Eric Lander, while working for Collins in the tortoise-paced Human Genome Project, who saw that his team was losing and made it his business to beat Venter's harelike private venture at its own game.
With $34 million from the Genome Project and a $38 million loan from M.I.T.'s Whitehead Institute, Lander ordered dozens of special-purpose computers and state-of-the-art capillary machines and built a huge automated gene-sequencing pipeline so insatiable that he was soon grabbing long stretches of DNA from other labs to feed its monstrous appetite.
Lander, 47, a math prodigy who learned genetics in his spare time, has always seemed a little larger than life.
time-proxy.yaga.com /time/subscriber/2004/time100/scientists/100lander.html   (382 words)

  
 PBS - Scientific American Frontiers:The Gene Hunters:Science Hotline:Eric Lander
Lander, a geneticist, molecular biologist, and mathematician, is the founder and director of the Whitehead Institute Center for Genome Research, one of the world's leading genome centers.
Dr. Lander was named a Rhodes Scholar in 1978 and received a MacArthur Foundation Fellowship in 1987.
Under Dr. Lander's leadership, the Center for Genome Research has been responsible for developing most of the key tools of modern genomics, the study of a mammal's genetic code and how it functions.
www.pbs.org /saf/1202/hotline/hlander.htm   (234 words)

  
 PBS - Scientific American Frontiers:The Gene Hunters:Resources:Transcript
ERIC LANDER was the lead author on the scientific paper that announced the first draft of the human genome.
ERIC LANDER Well, it's possible to over-hype all this stuff and I think people have outrageous expectations that there are going to be cures next week from all of this.
ERIC LANDER Well, you take your body in, to medicine, and for the past century we didn't know what the parts were.
www.pbs.org /saf/1202/resources/transcript.htm   (8209 words)

  
 HHMI's BioInteractive - Eric S. Lander, Ph.D.
In many ways, Eric Lander’s career has taken as many twists and turns as there are in the helical strands of DNA that he now spends his time trying to decode.
Lander was a quick study and a decent teacher, but economics did not provide him with the intellectual stimulation he needed.
Lander secured a position as a fellow at the Whitehead Institute for Biomedical Research, where he set to work on the problem.
www.biointeractive.org /genomics/lander.html   (1156 words)

  
 The Harvard Crimson :: News :: Broad Director Lander Joins HMS
MIT Professor and Director of the Broad Institute Eric Lander join the faculty of Harvard Medical School (HMS) this month, in a move that further ensures equal participation between Harvard and MIT at the soon-to-be launched Broad Institute.
Lander is one of Broad’s four core founding members, along with David M. Altshuler, Stuart L. Schreiber and Todd R. Golub—all of whom are Harvard faculty members.
Lander said that though a definite site has not been announced, Broad will be located in Kendall Square—a central location between Harvard and MIT.
www.thecrimson.com /article.aspx?ref=358211   (604 words)

  
 Broad Press Release - Eric Lander Featured in TIME Magazine as one of the World's 100 Most Influential People
In the April 26, 2004 special issue of TIME magazine, Eric Lander, founder and director of the Eli and Edythe L. Broad Institute, is featured as one of the world's 100 most influential people.
Lander is cited most recently as the visionary behind the creation of the Broad, harnessing the talent of MIT, Harvard and its hospitals and Whitehead Institute, to tackle the big questions facing biomedical science today.
Lander is Professor of Biology at MIT, Professor of Systems Biology at Harvard Medical School and Member of Whitehead.
www.broad.mit.edu /media/2004/time_lander_0422.html   (323 words)

  
 David Lander   (Site not responding. Last check: 2007-10-08)
David Lander: You once told me that, when you were a youngster, you thought Latino music was the music of America.
Lander, Crystal and Justinn of Antioch have named their son, born Nov....
In addition to acting, Lander, a Pittsburgh Pirates fan, has a small stake in the Portland Beavers, and has been a baseball talent scout since 1997, for the Anaheim Angels, and now the Seattle Mariners.
david-lander.wikiverse.org   (322 words)

  
 Human Genome News Vol.10,No.1-2, February 1999
According to Eric Lander, "People today are now living through the most stunning information revolution, unlike anything before in the history of science." He compared its importance to the chemist Mendeleev's critical observation around 1869 that all the elements of matter could be organized in a very simple table.
Bizarre machines are being built, Lander said as he showed a picture of a machine at Whitehead nicknamed the Genomatron, which can set up 100,000 PCR reactions in an hour.
As the audience laughed, Lander pointed out that if the subject were Alzheimer's disease or thrill seeking, it's not clear where the public would draw the line regarding behavior or other traits that might be explained by genes.
www.ornl.gov /sci/techresources/Human_Genome/publicat/hgn/v10n1/13lander.shtml   (955 words)

  
 CSBi :: Eric Lander   (Site not responding. Last check: 2007-10-08)
The Lander laboratory’s research entails understanding genes and gene products and how they work in the cell, looking at the circuits in which they work, and understanding genetic variation in the population.
The Lander laboratory collaborates with various groups at the Broad Institute in a number of areas.
Singer J.B., Hill A.E., Naduau J.H. and Lander E.S. Mapping quantitative trait loci for anxiety in chromosome substitution strains of mice.
csbi.mit.edu /faculty/Members/Eric   (361 words)

  
 Newswise
Lander, a member of the Whitehead Institute and founder and director of the Whitehead Center for Genome Research, is recognized for his inspired commitment to the Human Genome Project.
Lander served as chairman of the group that analyzed the entire, completed genome sequence.
Lander, who at 17 won a $10,000 scholarship in the Westinghouse Science Talent Search with a paper on quasi-perfect numbers, earned a B.A. in mathematics from Princeton University in 1978 and a D.Phil.
www.newswise.com /articles/view/35850   (1032 words)

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