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Topic: Erythromelalgia

Related Topics

Autosomal dominant

Essential thrombocytosis

Polycythaemia

Silas Weir Mitchell

Hyposplenism

Hydroxyurea

Thrombocytosis

	Erythromelalgia - Wikipedia, the free encyclopedia
		Erythromelalgia, also known as Mitchell's disease (after Silas Weir Mitchell) and red neuralgia, is a rare disorder in which blood vessels, usually in the extremeties and especially in the feet, are blocked and inflamed, causing a painful burning and throbbing sensation and red skin.
		Erythromelalgia is often associated with vascular diseases such as polycythaemia vera, thrombocytosis or with heavy metal poisoning.
		Erythromelalgia (in a mild form) can be detected by a stiff feeling, swelling, or redness in the limbs.
	en.wikipedia.org /wiki/Erythromelalgia (249 words)

	Dr. Pribut on Erythromelalgia
		Drenth and Michiels (1994, 1995) proposed using the terms erythromelalgia for a platelet-mediated form that is responsive to aspirin and use the terms primary and secondary erythermalgia for non-aspirin sensitive forms of the disorder.
		Secondary erythromelalgia caused by myeloproliferative disorders seem to occur in a male to female ratio of 3:2.
		Michiels JJ, Drenth JP, Van Genderen PJ: Classification and diagnosis of erythromelalgia and erythermalgia.
	www.drpribut.com /sports/erythromelalgia.htm (459 words)

	The Erythromelalgia Association
		Erythromelalgia (EM) is a rare condition that can cause redness and pain in all parts of the body, most frequently the feet and hands (extremities), but also in the face, ears, limbs and torso.
		However, the condition is thought to result from vasomotor abnormalities or dysfunction in the normal constriction and dilation of the diameter of certain blood vessels, leading to abnormalities of blood flow to the extremities.
		Erythromelalgia may be an isolated, primary condition or occur secondary to various underlying disorders.
	www.erythromelalgia.org (245 words)

	THE MERCK MANUAL, Sec. 16, Ch. 212, Peripheral Vascular Disorders
		Secondary erythromelalgia may occur in patients who have myeloproliferative disorders, hypertension, venous insufficiency, diabetes mellitus, SLE, RA, lichen sclerosus et atrophicus, gout, spinal cord disease, or multiple sclerosis.
		Diagnosis of erythromelalgia is based on the relationship of complaints to increased skin temperature.
		Because erythromelalgia may precede a myeloproliferative disorder (even by several years), frequent blood counts may be indicated to allow early diagnosis and treatment of the latter.
	www.merck.com /mrkshared/mmanual/section16/chapter212/212f.jsp (242 words)

	Lessons from Erythromelalgia, Raynauds, RSD, Causalgia, Cluster Headaches for Flushing Pain?
		Erythromelalgia is a rare condition, but we are convinced that pathogenetic mechanisms of this condition can reveal mechanisms relevant for other large groups of patients with disturbances in distribution of microvascular blood perfusion, such as patients with diabetes mellitus, septic shock, multiorgan failure, scleroderma, or leg ulcers...
		Erythromelalgia: a clue to the diagnosis of polycythemia vera.
		Erythromelalgia is a painful disorder of the extremities characterized by redness, swelling, a burning sensation, and an increase in skin temperature exacerbated by exposure to heat.
	www.angelfire.com /journal2/sadhelp/emd.htm (7855 words)

	Erythromelalgia - New Treatments, May 2, 2006 (Site not responding. Last check: 2007-10-31)
		Primary erythromelalgia is a rare syndrome of paroxysmal vasodilatation with burning pain, increased skin temperature, and redness of the feet and, less often, the hands.
		Erythromelalgia is as common in children as adults, but in children it is less likely to be associated with erythromelalgia.
		Secondary erythromelalgia should be differentiated from the more common primary disorder because in the former, correction of the underlying disorder may relieve symptoms.
	www.ccspublishing.com /journals3a/erythromelalgia.htm (306 words)

	Erythromelalgia - WrongDiagnosis.com
		Erythromelalgia is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH).
		This means that Erythromelalgia, or a subtype of Erythromelalgia, affects less than 200,000 people in the US population.
		With a diagnosis of Erythromelalgia, it is also important to consider whether there is an underlying condition causing Erythromelalgia.
	www.wrongdiagnosis.com /e/erythromelalgia/intro.htm (341 words)

	Erythromelalgia
		Erythromelalgia is a rare condition that primarily affects the feet and, less commonly, the hands (extremities).
		However, the condition is thought to result from vasomotor abnormalities or dysfunction in the normal narrowing (constriction) and widening (dilation) of the diameter (caliber) of certain blood vessels, leading to abnormalities of blood flow to the extremities.
		Primary erythromelalgia may appear to occur randomly for unknown reasons (sporadically) or may be familial, suggesting autosomal dominant inheritance.
	www.webmd.com /hw/skin_and_beauty/nord245.asp (540 words)

	eMedicine - Erythromelalgia : Article by Robert J Nardino, MD
		Secondary erythromelalgia was reported to have a male-to-female ratio of 3:2 in a review of 60 cases of erythromelalgia due to myeloproliferative disorders.
		Erythromelalgia manifests before the appearance of a myeloproliferative disorder in 85% of cases.
		Biopsy specimens in patients with primary erythromelalgia show mild mononuclear perivascular infiltrates with edema, thickened vascular basement membranes, and moderate endothelial swelling; the intimal thickening and thrombi seen in secondary erythromelalgia are lacking.
	www.emedicine.com /med/topic730.htm (2570 words)

	eMedicine - Erythromelalgia : Article Excerpt by: Robert J Nardino, MD
		Confusion exists in the literature concerning nomenclature and classification; however, in general, a distinction is made between primary (idiopathic) and secondary erythromelalgia (most commonly associated with myeloproliferative disorders), as well as between early- and late-onset disease.
		Several factors postulated to contribute to primary erythromelalgia are postganglionic sympathetic dysfunction; hypersensitivity of C-fibers; and maldistribution of skin perfusion resulting from arteriovenous shunting, which leads to an imbalance between thermoregulatory and nutritive perfusion.
		Early-onset erythromelalgia (or primary erythermalgia by the Drenth-Michiels classification) is rare, with fewer than 30 cases reported in the literature.
	www.emedicine.com /med/byname/erythromelalgia.htm (549 words)

	AccessMedicine - Harrison's Internal Medicine: Erythromelalgia (Erythermalgia)
		Erythromelalgia may occur at any age but is most common in middle age.
		It may be primary or secondary to myeloproliferative disorders such as polycythemia vera and essential thrombocytosis, or it may occur as an adverse effect of drugs such as nifedipine or bromocriptine.
		Erythromelalgia can be distinguished from ischemia secondary to peripheral arterial disorders and peripheral neuropathy because the peripheral pulses are present and the neurologic examination is normal.
	www.accessmedicine.com /content.aspx?aID=83532 (279 words)

	erythromelalgia
		Erythromelalgia is a rare condition that can cause redness and pain in all parts of the body, but most frequently the feet and hands (extremities).
		With the help of the members of The Erythromelalgia Association (TEA), their doctors, and future research, control of EM symptoms is entirely feasible.
		In his article, “Erythromelalgia: New theories and therapies”, Dr. Cohen discusses a wide variety of possible approaches including the use of topical treatments, oral medications, drug infusions, surgical intervention, medical devices and non-medical therapies.
	www.btinternet.com /~tetheredcordresources/erythromelalgia.htm (2339 words)

	Molecular Basis for Pain and Inflammation in Erythromelalgia
		The study demonstrates that a mutation in the sodium channel Nav 1.7 causes over-excitability in one type of neuron and under-excitability in another type of neuron, according to Stephen Waxman, M.D., chair of the Department of Neurology and director of the West Haven Veteran Administration Rehabilitation Research Center.
		Erythromelalgia is characterized by attacks of burning pain that are often triggered by a slight elevation in skin temperature.
		The mutation predisposes pain-signaling neurons to be over-excitable and fire rapid bursts of impulses in response to normally non-painful stimuli.
	www.yale.edu /opa/newsr/06-05-22-01.all.html (458 words)

	The use of regional anaesthetic blockade in a child with recurrent erythromelalgia -- Harrison et al. 88 (1): 65 -- ...
		The use of regional anaesthetic blockade in a child with recurrent erythromelalgia -- Harrison et al.
		Continuous epidural infusion of bupivacaine and fentanyl for erythromelalgia in an adolescent.
		Erythromelalgia and other disturbances of the extremities accompanied by vasodilatation and burning.
	adc.bmjjournals.com /cgi/content/full/88/1/65 (1045 words)

	Erythromelalgia
		You have a rare problem, that is almost the opposite of Raynaud's, in which the fingers and toes turn color and get painful with exposure to cold.
		With erythromelalgia, the hands and feet get very red and painful in a warm environment.
		Erythromelalgia may be associated with high blood pressure, too many platelets or red cells in the blood, or a side effect of medications like nifedipine (blood pressure medicine).
	healthlink.mcw.edu /article/990317252.html (254 words)

	Erythromelalgia - The "red limb pain" disease (Site not responding. Last check: 2007-10-31)
		Erythromelalgia is a type of nerve pain — known as neuropathic pain — and is akin to the kind experienced by millions of people with diabetes, shingles, multiple sclerosis and AIDS.
		That’s why Waxman and seven other scientists studying erythromelalgia are excited they’ve finally found what’s wrong with Costa and the nearly 40 members of her extended family who also have the condition.
		Even now, many people with erythromelalgia sit for hours soaking their feet in cool water, something that can damage the skin so badly that infections set in and force amputations.
	www.ama-ama.info /articles/erythromelalgia.html (1286 words)

	Erythromelalgia. DermNet NZ
		Erythromelalgia is a condition characterised by intense burning pain, erythema (marked redness), and increased skin temperature, primarily of the feet and hands.
		The classic description of erythromelalgia is red, painful, warm hands or feet, brought on by warming or hanging the limb downward, and relieved with cooling and elevation.
		Erythromelalgia may be an early sign of polycythaemia or thrombocythaemia, where symptoms may precede diagnosis of the myeloproliferative disorder by 2.5 years.
	www.dermnetnz.org /vascular/erythromelalgia.html (872 words)

	[No title] (Site not responding. Last check: 2007-10-31)
		Calcium channel blockers worsened his erythromelalgia symptoms as noted in the literature.
		I suspect this is erythromelalgia (sometime called erythermelalgia) and can only remember seeing one similar case in the distant past.
		The suggestion of a localized scarletiniform eruption was interesting, and reaction to bacterial exotoxin similar to that seen with TSS and SSSS should have been considered.
	matrix.ucdavis.edu /rxderm-archives/erythromelalgia (1037 words)

	Erythromelalgia
		Erythromelalgia is a condition affecting the extremely small blood vessels in the body (micro-circulation).
		Burning pain of red and warm hands and/or feet are the classical symptoms of erythromelalgia, the feet being predominantly involved.
		The condition may be associated with underlying illness that can take time to become apparent and some doctors recommend ongoing surveillance of patients with erythromelalgia in order to detect any disorders as they develop.
	www.netdoctor.co.uk /ate/skinandhair/206838.html (247 words)

	Erythromelalgia - erythromelalgia of the face
		The attacks come and go, and tend to photos of erythromelalgia of the face be worse in summer.
		Erythromelalgia responds to cooling, and often disappears completely yale erythromelalgia on taking non-steroidal anti-inflammatory drugs, such as aspirin.
		The broader body of knowledge about diseases and their treatments is medicine.
	www.medicalgeo.com /Med-Diseases-E/Erythromelalgia.html (216 words)

	Fox Mill Foot and Ankle Center > Erythromelalgia
		You are in Foot Problems > Vascular Problems > Erythromelalgia.
		Erythromelalgia is a rare disorder that includes enlargement of the blood vessels in the feet.
		The blood vessels are open or dilated and the oxygen and heat of the blood is discharged into the tissues, making them turn red and feel hot all the time.
	www.footdoctorva.com /prob_vascular_eryth.php (171 words)

	Mayo Clinic Proceedings
		Erythromelalgia is a term that describes the clinical syndrome of red, hot extremities.
		Primary and secondary forms of erythromelalgia have been described.
		Recent evidence indicates that a small-fiber neuropathy is associated with erythromelalgia.
	www.mayoclinicproceedings.com /inside.asp?AID=509&UID= (236 words)

	Symptoms of Erythromelalgia - WrongDiagnosis.com
		Note that Erythromelalgia symptoms usually refers to various symptoms known to a patient, but the phrase Erythromelalgia signs may refer to those signs only noticable by a doctor:
		When considering symptoms of Erythromelalgia, it is also important to consider Erythromelalgia as a possible symptom of other medical conditions.
		This signs and symptoms information for Erythromelalgia has been gathered from various sources, may not be fully accurate, and may not be the full list of Erythromelalgia signs or Erythromelalgia symptoms.
	www.wrongdiagnosis.com /e/erythromelalgia/symptoms.htm (274 words)

	Erythromelalgia, burning feet and lower leg pain - Health and Medical Information produced by doctors - MedicineNet.com
		Erythromelalgia, burning feet and lower leg pain - Health and Medical Information produced by doctors - MedicineNet.com
		I have had the symptoms of burning feet and lower leg pain for 2 years.
		Though, this may not be what I have; I have had to live a much more limited life than I am used to.
	www.medicinenet.com /script/main/art.asp?articlekey=19992 (174 words)

	KickAS: Raynauds & Erythromelalgia
		I'm not sure if this is the right forum for this post but as I'm sure some of it is connected with starch I've put it here.
		The thing with starch is that most times when I do indulge, my ears turn bright red and burn.
		Erythromelalgia is most commonly in the limbs, but can affect the face and ears.
	www.kickas.org /ubbthreads/showflat.php?Number=215319 (653 words)

	Erythromelalgia (Site not responding. Last check: 2007-10-31)
		Erythromelalgia Brief Summary A condition of vasodilation of the small vessels of the feet(& sometimes the hands) which presents as burning pain, redness, and local heat.
		Secondary it can be the result of myeloproliferative disorders, hypertension, diabetes, rheumatoid arthritis, venous insufficiency and a variety of other disorders.
		In primary erythromelalgia, be certain to have periodic blood work up for possible myeloproloiferative disorders (ie.
	www.podiatrynetwork.com /subject_detail.cfm?id=435 (243 words)

	Headache: Encyclopedia of Neurological Disorders
		CLUSTER HEADACHES Cluster headaches are recurrent brief attacks of sudden and severe pain on one side of the head, usually most intense in the area around the eye.
		Other names for these headaches include histamine cephalalgia, Horton neuralgia, or erythromelalgia.
		Cluster headaches may last between five minutes and three hours; they may occur once every other day or as often as eight times per day.
	health.enotes.com /neurological-disorders-encyclopedia/headache (4492 words)

	NEJM -- Treatment of Primary Erythromelalgia with Cyclosporine
		NEJM -- Treatment of Primary Erythromelalgia with Cyclosporine
		Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.
		--> To the Editor: Erythromelalgia is a rare disease of unknown
	content.nejm.org /cgi/content/short/349/8/816 (126 words)

	Erythromelalgia (Site not responding. Last check: 2007-10-31)
		• Erythromelalgia • Ischemic Foot • Neuroma • Neuroma • Neuroma • Spasms • Spasms • Venous Stasis • Venous Stasis
		More than 15 percent of American adults suffer from chronic facial pain, typically in or around the ear and the jaw.
		The pain is often accompanied by clicking or popping noises when opening the mouth, or even headaches and neck aches.
	www.drrun.com /sub.php?page=prob_vascular_eryth (195 words)

	Arch Dermatol -- Abstract: Erythromelalgia: Vasculopathy, Neuropathy, or Both?: A Prospective Study of Vascular and ... (Site not responding. Last check: 2007-10-31)
		Arch Dermatol -- Abstract: Erythromelalgia: Vasculopathy, Neuropathy, or Both?: A Prospective Study of Vascular and Neurophysiologic Studies in Erythromelalgia, October 2003, Davis et al.
		changes and neurologic abnormalities in patients with erythromelalgia.
		Erythromelalgia -- Cutaneous Pain Syndrome or Vascular Abnormality?
	archderm.ama-assn.org /cgi/content/abstract/139/10/1337 (376 words)

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