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Topic: Essential thrombocytosis

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	eMedicine - Thrombocytosis : Article by Susumu Inoue
		Primary thrombocytosis is a component of a myeloproliferative disorder (eg, essential thrombocythemia, myelofibrosis with myeloid metaplasia, polycythemia vera, chronic myelocytic leukemia [rare]) or, in rare cases, of acute myelocytic leukemia.
		In pediatrics, primary thrombocytosis is exceedingly rare, whereas secondary, or reactive, thrombocytosis is common, particularly in infants.
		Older children with thrombocytosis with thrombosis (suspected or demonstrated) or a history of thrombosis, increased bleeding tendency despite thrombocytosis, or splenomegaly must promptly be referred to a hematologist.
	www.emedicine.com /ped/topic2238.htm (4632 words)

	Essential thrombocytosis - guideofcasinos.com (Site not responding. Last check: 2007-10-24)
		Essential thrombocytosis (ET, essential thrombocythemia) is a rare chronic blood disorder characterized by the overproduction of platelets by megakaryocytes (the precursor cell for platelets) in the absence of an alternative cause.
		Essential thrombocytosis is diagnosed at a rate of about 2 to 3 per 100,000 individuals and usually affects middle aged to elderly individuals, although it can affect children and young adults.
		Essential thrombocytosis is a slowly progressive disorder with long asymptomatic periods punctuated by thrombotic or hemorrhagic events.
	www.guideofcasinos.com /Essential_thrombocytosis.html (592 words)

	Essential thrombocytosis - Biocrawler (Site not responding. Last check: 2007-10-24)
		Essential thrombocytosis (ET, essential thrombocythemia) is a rare and chronic blood disorder characterized by the overproduction of platelets (thrombocytosis).
		It is one of four rare myeloproliferative diseases in which an overproduction of blood platelet precursor cells (megakaryocytic hyperplasia) leads to an overproduction in blood platelets (peripheral thrombocytosis).
		Aside from the overproduction of platelets, symptoms of ET include an enlarged spleen (splenomegaly), epistaxis (nosebleeds) and bleeding from gums and gastrointestinal tract.
	www.biocrawler.com /encyclopedia/Essential_thrombocytosis (201 words)

	essential thrombocytosis prognosis (Site not responding. Last check: 2007-10-24)
		Essential thrombocytosis prognosis applicability essential thrombocytosis prognosis be essential thrombocytosis prognosis to assess the extent to which the intervention might be useful in a particular setting or population.
		If local essential thrombocytosis prognosis and essential thrombocytosis prognosis essential thrombocytosis prognosis the use of strongly essential thrombocytosis prognosis and recommended interventions should be initiated or essential thrombocytosis prognosis A starting essential thrombocytosis prognosis for communities essential thrombocytosis prognosis health-care systems is to essential thrombocytosis prognosis current tobacco-use prevention and cessation activities.
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	hometown.aol.com /woman1having1sex/essential-thrombocytosis-prognosis.html (382 words)

	Thrombocytosis
		Thrombocytosis is a blood disorder in which the body produces a surplus of platelets (thrombocytes).
		Thrombocytosis is an abnormally increased number of platelets in the blood.
		Primary thrombocytosis (or essential thrombocythemia) is a single disease entity, with unique clinical characteristics.
	www.healthatoz.com /healthatoz/Atoz/ency/thrombocytosis.jsp (534 words)

	Thrombocythemia, Essential
		Essential thrombocythemia (ET) is one of four rare myeloproliferative disorders (an overabundance of cells produced in bone marrow) each of which is characterized by overproduction of a different but essential blood cell.
		Symptoms of essential thrombocythemia vary from case to case but are related to the formation of blood clots (thrombosis) leading, on occasion, to dangerous consequences, and paradoxically to episodes of active bleeding (hemorrhaging).
		The treatment of essential thrombocythemia varies depending on the symptoms that are present and on the patient’s risk factors for development of a dangerous blood clot (thrombosis) and the patient’s predisposition to develop a malignant successor disorder like leukemia or myelofibrosis.
	hw.healthdialog.com /kbase/nord/nord577.htm (2134 words)

	Essential Thrombocytosis Resources (Site not responding. Last check: 2007-10-24)
		thrombocytosis is a medical term used to describe a high number of circulating platelets in the blood.
		essential thrombocytosis essential thrombocytosis (et, essential thrombocythemia) is a rare and chronic blood disorder characterized by the.
		thrombocytosis, essential - essential thrombocytosis (et), first described by epstein and goedel in 1934, is a nonreactive, chronic myeloproliferative...
	essentials.mmtraders.co.uk /essential+thrombocytosis-base.htm (164 words)

	CIGNA - Thrombocythemia, Essential (Site not responding. Last check: 2007-10-24)
		Essential thrombocythemia is characterized by overproduction of the precursor cells to blood platelets (megakaryocytes) which, in turn, leads to a vastly increased number of platelets in the blood.
		The treatment of essential thrombocythemia varies depending on the age and sex of the affected individual and the risk for blood clots or thromboses as measured by platelet counts per micro-liter of blood.
		Michiels JJ, Thieles J. Clinical and pathological criteria for the diagnosis of essential thrombocythemia, polycythemia vera, and idiopathic myelofibrosis (agnogenic myeloid metaplasia).
	www.cigna.com /healthinfo/nord577.html (2092 words)

	THE MERCK MANUAL OF GERIATRICS, Ch. 71, Chronic Myeloid Disorders
		Acquired von Willebrand's disease is a rare complication associated with extreme thrombocytosis and is related to abnormal platelet adsorption of circulating von Willebrand's multimers.
		Shorter duration of thrombocytosis, low levels of serum ferritin (which is diagnostic of iron depletion), and an increase in C-reactive protein suggest secondary thrombocythemia.
		The thrombocytosis and hepatomegaly may be controlled transiently with hydroxyurea (starting dosage, 500 mg po tid) or 2-chlorodeoxyadenosine (0.14 mg/kg given over 2 hours IV daily for 5 days).
	www.merck.com /mrkshared/mmg/sec9/ch71/ch71b.jsp (2582 words)

	Acta Cardiologica
		Essential thrombocytosis is a chronic disease characterized by both quantitative and qualitative abnormalities of platelets.
		Cardiovascular complications may develop in patients with essential thrombocytosis due to an abnormal thrombogenic and haemorrhagic tendency.
		In the present case, we report two cases in which essential thrombocytosis manifested as cardiovascular complication, one of the patients had a history of anterior myocardial infarction, and the other one had congestive heart failure.
	poj.peeters-leuven.be /content.php?url=article&id=2004938&journal_code=AC (93 words)

	Thrombocytosis - essential thrombocytosis
		Thrombocytosis is the presence of high platelet counts in the blood, and can be either reactive or primary (also termed essential and caused by a myeloproliferative disease).
		High sepsis and thrombocytosis leukocyte endothelial adhesion and thrombocytosis platelet levels do not necessarily signal any clinical problems, and are picked up on a routine full blood count.
		Laboratory hydroxyurea essential thrombocytosis essential thrombocytosis essential thrombocytosis new medicine research 2005 tests might include: full blood count, liver enzymes, renal function and erythrocyte sedimentation rate.
	www.medicalgeo.com /Med-Diseases-T/Thrombocytosis.html (487 words)

	Essential thrombocytosis
		Essential thrombocytosis is the most rare of the myeloproliferative family of diseases.
		One characteristic symptom is throbbing and burning of the hands and feet due to the occlusion of small arterioles by platelets (erythromelalgia).
		Essential thrombocytosis is a slowly progressing disorder with long asymptomatic periods punctuated by thrombotic or hemorrhagic crises.
	www.mrsci.com /Hematology/Essential_thrombocytosis.php (258 words)

	AccessMedicine - Harrison's Internal Medicine: Essential Thrombocytosis
		"Essential thrombocytosis (other designations include essential thrombocythemia, idiopathic thrombocytosis, primary thrombocytosis, hemorrhagic thrombocythemia) is a clonal disorder of unknown etiology involving a multipotent hematopoietic progenitor cell and is manifested clinically by the overproduction of platelets without a definable cause.
		Essential thrombocytosis is an uncommon disorder, but its exact frequency is unknown.
		As a consequence, essential thrombocytosis was formerly considered to be a disease of the elderly and to be responsible for significant morbidity due to hemorrhage or thrombosis.
	www.accessmedicine.com /content.aspx?aID=65297 (270 words)

	Reference.com/Encyclopedia/Essential thrombocytosis
		Essential thrombocytosis (ET, also known as essential thrombocythemia) is a rare chronic blood disorder characterized by the overproduction of platelets by the bone marrow in the absence of an alternative cause.
		Essential thrombocytosis is diagnosed at a rate of about 2 to 3 per 100,000 individuals annually.
		In 2005, a mutation in the JAK2 kinase (V617F) was found by multiple research groups to be associated with essential thrombocytosis in around 30% of cases.
	www.reference.com /browse/wiki/Essential_thrombocytosis (643 words)

	Essential Thrombocythemia: Myeloproliferative Disorders: Merck Manual Professional
		Essential thrombocythemia is characterized by an increased platelet count, megakaryocytic hyperplasia, and a hemorrhagic or thrombotic tendency.
		Essential thrombocythemia (ET) is a typically clonal abnormality of a multipotent hematopoietic stem cell.
		To distinguish from other myeloproliferative disorders that produce thrombocytosis, the diagnosis of ET requires a normal Hct, MCV, and iron studies; absence of the Philadelphia chromosome and ABL-BCR translocation (present in chronic myelocytic leukemia); and absence of teardrop-shaped RBCs and significant increase in bone marrow fibrosis (present in idiopathic myelofibrosis).
	www.merck.com /mmpe/sec11/ch141/ch141b.html (777 words)

	Pituitary Thalassemia Trait Thrombocytosis (Site not responding. Last check: 2007-10-24)
		thrombocytosis or leukocytosis most commonly in myeloproliferative clots disorders because blood clotting the.
		Anemia alpha blocker alpha 1 antitrypsin deficiency alpha thalassemia Alport essential thrombocythemia (thrombocytosis) essential tremor hypothalamic lesion hypothalamic pituitary pressure abnormality hypothermia 27.
		Essential Thrombocytosis (21 recruiting studies) ATR X (X linked alpha thalassemia mental essential thrombocytosis.
	www.leavenworthvillagevoices.com /pituitary-thalassemia-trait-thrombocytosis.htm (209 words)

	Essential Thrombocythemia - Synonym Of Essential Thrombocytosis
		NCI recognizes essential thrombocytosis as a synonym of essential thrombocythemia.
		Essential Thrombocythemia: A clonal abnormality initiated by the transformation of a...
		Idiopathic (or Essential) is a term used to indicate that the cause for a...
	www.medicality.org.uk /diseases/essential-thrombocythemia---synonym-of-essential-thrombocytosis.php (192 words)

	eMedicine - Thrombocytosis, Essential : Article by Asheesh Lal, MBBS
		Background: Essential thrombocytosis (ET), first described by Epstein and Goedel in 1934, is a nonreactive, chronic myeloproliferative disorder.
		The hallmark of ET is a sustained, unexplained thrombocytosis.
		Chistolini A, Mazzucconi MG, Ferrari A: Essential thrombocythemia: a retrospective study on the clinical course of 100 patients.
	www.emedicine.com /med/topic2266.htm (3749 words)

	Treat thrombocytosis, moderate thrombocytosis and treatment, not responding to prescription drugs, scientifically — ...
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		Kawasaki's disease is a rare condition, mainly affecting children, in which there is widespread inflammation of the arteries.
	www.drraomd.com /diseaseindex/b_blood_thrombocytosis.htm (870 words)

	ETFAQ
		Thrombocythemia (or thrombocytosis) is defined as the occurence of a platelet count in excess of 400,000 per microliter in the setting of a myeloproliferative disease.
		The diagnosis of essential thrombocythemia is primarily one of exclusion.
		In patients ranging from age 28-86 with essential thrombocythemia at platelet counts between 300,000 and 1 million, followed for a median of 45 months, "minor manifestations" of ET included headache, dizziness, tinnitus, visual disturbances, erythromelalgia, parathesias, leg pain, digital cyanosis.
	www.acor.org /mpd/etfaq.html (5078 words)

	Essential thrombocytosis - essential thrombocytosis research 2005
		The essential thrombocytosis non-familial pathologic basis for this disease is unknown.
		Platelets derived from the abnormal megakaryocytes do not function properly, which contributes to the clinical features of bleeding essential thrombocytosis research 2005 and thrombosis.
		A disease is any abnormal condition of the body or mind that causes discomfort, dysfunction, or distress to the person affected or those in contact with the person.
	www.medicalgeo.com /Med-Diseases-E/Essential-thrombocytosis.html (358 words)

	Thrombocytosis and essential thrombocythaemia
		Thrombocytosis is a medical term used to describe a high number of platelets in your blood.
		Platelets are essential to stem bleeding, but if you have too many it can cause clots to form when you don't need them (thrombosis).
		If you have a high platelet count because you have a blood disorder that affects the makeup of the blood itself, this is known as primary or essential thrombocytosis and bleeding and clotting, though rare, are more likely.
	www.netdoctor.co.uk /diseases/facts/thrombocytosis.htm (3158 words)

	BCMD Issue 7, 1999
		Reactive thrombocytosis is different than primary or essential thrombocytosis which is usually related to myeloproliferative neoplasia.
		Essential thrombocytosis is most common in adults, whereas reactive thrombocytosis is most frequently observed in children.
		All challenged rabbits demonstrated some degree of thrombocytosis in response to the infection, but individual rabbits were varied in their pattern of thrombocytosis.
	www.scripps.edu /bcmd/is199907.html (910 words)

	JournalResponse.com - Essential thrombocytosis and myocardial infarction in an aircrew member: aeromedical concerns.
		JournalResponse.com - Essential thrombocytosis and myocardial infarction in an aircrew member: aeromedical concerns.
		Essential thrombocytosis and myocardial infarction in an aircrew member: aeromedical concerns.
		Of essential thrombocytosis (ET) cases, 25% occur in patients younger than 40 yr of age, and are often discovered as an incidental laboratory abnormality.
	www.journalresponse.com /index.php?a=topic&t=16422458 (89 words)

	Essential thrombocytosis - (Site not responding. Last check: 2007-10-24)
		Essential thrombocytosis (ET, essential thrombocythemia) is a rare and chronic blood disorder characterized by the overproduction of megakaryocytes (the precursor cell for platelets).
		Recently, in 2005, a mutation in the JAK2 kinase (V617F) was found by multiple research groups (Baxter et al., 2005; Levine et al., 2005) to be associated with essential thrombocytosis.
		}} Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis{{qif
	www.gurgaongrid.com /mediawiki/index.php/Essential_thrombocytemia (398 words)

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