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Topic: Fasciola hepatica


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In the News (Wed 30 Dec 09)

  
  The Liver Fluke Fasciola hepatica
hepatica is the causative agent of Fascioliasis, or 'liver rot' in ruminants, where it may be an important pathogen.
hepatica is a typical example of a Digenean lifecycle, with miracidial, and cercarial stages.
In addition, as described above, as Fasciola does not appear to be fully adapted to using man as a definitive host, the flukes may often give rise to ectopic infections, particularly in the lungs and subcutaneous tissues, where they may be found encysted.
www.path.cam.ac.uk /~schisto/OtherFlukes/Fasciola.html   (1347 words)

  
 Tropical Medicine Central Resource
Fascioliasis is an infection by the sheep liver fluke Fasciola hepatica (Figs.
hepatica was initially described by Jean DeBrie in 1379 and was later identified in the livers of sheep and goats in 1547 and in humans in 1600.
Fasciola hepatica is found worldwide with a high infection rate among herbivorous animals.
tmcr.usuhs.mil /tmcr/chapter21/otherfas.htm   (328 words)

  
 Fasciola hepatica - The Merck Veterinary Manual
Eggs of F hepatica cannot be demonstrated in feces during acute fasciolosis.
Control measures for F hepatica ideally should involve removal of flukes in affected animals, reduction of the intermediate host snail population, and prevention of livestock access to snail-infested pasture.
In areas where heavy infections are expected, sheep may require treatment in September or October, January or February, and again in April or May to reduce both the chances of acute or chronic infections and the output of fluke eggs for development of future disease.
www.merckvetmanual.com /mvm/htm/bc/22702.htm   (947 words)

  
 Lab6   (Site not responding. Last check: 2007-11-04)
Fasciola hepatica has 2 generations of redia, the germinal cells of the second generation will develop into cercariae.
Metacercaria: This is the infective stage of Fasciola hepatica.
Be able to identify the adults of Fasciola hepatica, Dicrocoelium dendriticum, Fascioloides magna and Paramphistomum cervi (by size, shape and location within the host).
cal.vet.upenn.edu /paraav/labs/lab6.htm   (847 words)

  
 KIDNEY PATHOLOGY IN CATTLE NATURALLY INFECTED BY FASCIOLA HEPATICA
The immunohistochemical analysis revealed a positive reaction for the antigen (the presence of diffuse brown antigens) of Fasciola hepatica in the glomerulus and vascular pole.
In addition, the immunohistochemical detection of Fasciola hepatica antigen in glomeruli, and the presence of IgG are suggestive of disease mediated by immune complexes.
The positive results obtained through the immunofluorescent analysis of the renal tissue of cattle with Fasciola hepatica is clear evidence of antigen-antibody complexes with a granular and pseudolinear pattern in the mesangial and subendothelial regions.
www.isrvma.org /article/60_1_3.htm   (1889 words)

  
 Bioline International Official Site (site up-dated regularly)
The antigens of Paragonimus westermani, Schistosoma mansoni, and Fasciola hepatica adult worms.
Resistance to Schistosoma bovis in sheep induced by an experimental Fasciola hepatica infection.
Fasciola hepatica: Molecular cloning, nucleotide sequence, and expression of a gene encoding a polypeptide homologous to a Schistosoma mansoni fatty acid binding protein.
www.bioline.org.br /request?oc95049   (2219 words)

  
 Bioline International Official Site (site up-dated regularly)
From complete mitochondrial DNA sequence of Fasciola hepatica available in Genbank, specific primers were designed for a conserved and repetitive region of this trematode.
Fascioliasis is regarded to be one of the most important parasitic diseases in domestic ruminants of economical importance and its aethiological agent, Fasciola hepatica (Linnaeus, 1758), is a cosmopolitan trematode in areas of bovine, caprine, ovine, and buffaloes breading (Lessa et al.
hepatica is routinely performed either by exposing the snails to light in order to observe cercariae or by dissecting them to visualize cercariae, sporocysts, and redia, mainly when located into the digestive gland.
www.bioline.org.br /request?oc04074   (2451 words)

  
 Cloning and sequence analysis of genes encoding Fasciola hepatica immunodominant antigens
Cloning and sequence analysis of genes encoding Fasciola hepatica immunodominant antigens
Fasciola hepatica lambdagt11 cDNA expression library was immuno-screened with IPAb, two clones were isolated and identified as Fhlambda400 Fhlambda800.
Results revealed that the IPAb labeled the outer glycocalyx in a characteristic, pattern, which proved that the identified antigens were tegumental in origin and that infected Fasciola subjects induced antibodies directed mainly against tegumental components.
www.egeinfonet.i8.com /pub/2004/49.html   (218 words)

  
 Fasciola hepatica Suppresses a Protective Th1 Response against Bordetella pertussis -- Brady et al. 67 (10): 5372 -- ...   (Site not responding. Last check: 2007-11-04)
Fasciola hepatica-induced suppression of spleen mononuclear cell proliferation: role of nitric oxide.
Immunodiagnosis of Fasciola hepatica infection (fasciolosis) in a human population in the Bolivian altiplano using purified cathepsin L cysteine proteinase.
Fasciola hepatica infection induces potent Th2 responses in mice.
iai.asm.org /cgi/content/full/67/10/5372   (3933 words)

  
 Fascioliasis - Wikipedia, the free encyclopedia
Fascioliasis is caused by the trematodes Fasciola hepatica (the sheep liver fluke) and Fasciola gigantica, parasites of herbivores that can infect humans accidentally.
hepatica are found in areas where sheep and cattle are raised, and where humans consume raw aquatic plants like watercress, including Europe, the Middle East, and Asia.
No signs of Fasciola infection were observed in any animal given the plants of Liliaceae." cited from: Inst Anim Health Q (Tokyo).
en.wikipedia.org /wiki/Fascioliasis   (616 words)

  
 Medical Dictionary: Fasciola hepatica - WrongDiagnosis.com
Fasciola hepatica: Liver disease caused by infections with parasitic flukes of the genus FASCIOLA, such as FASCIOLA HEPATICA.
Fasciola hepatica: Another name for Fascioliasis (or close medical condition association).
Fasciola hepatica: Fasciola hepatica is listed as a type of (or associated with) the following medical conditions in our database: Biliary disorder, Gall bladder conditions, Liver conditions, Zoonotic Diseases
www.wrongdiagnosis.com /medical/fasciola_hepatica.htm   (243 words)

  
 parasite cleanse - Fasciola hepatica   (Site not responding. Last check: 2007-11-04)
hepatica are condemned as unsuitable for human consumption.
Another example of a Fasciola hepatica egg, showing the operculum.
A stained whole mount of an adult Fasciola hepatica; approximate length = 20 mm.
www.frequencyrising.com /parasite_fasciola.htm   (457 words)

  
 Allison C. Rice-Ficht   (Site not responding. Last check: 2007-11-04)
Fasciola hepatica eggshells are composed of at least three novel proteins which undergo the unusual post- translational modification of tyrosine to dihydroxyphenylalanine; this modification allows the proteins to undergo oxidation and crosslinking to form a hard, porous, quinone- tanned eggshell.
The long term goals of the project include a study of i) the concerted expression of these proteins in development, ii) the biochemistry of shell formation including crosslink structure and enzymology of shell formation (tyrosine hydroxylase, catechol oxidase), and iii) the application of recombinant eggshell proteins and worm processes to synthetic microencapsulation.
Fasciola hepatica (liver fluke) stained with molybdate-nitrate reagent to detect the presence of DOPA containing protein, the precursor to eggshell.
pauling.tamu.edu /medbiogen/arf.html   (1276 words)

  
 DNA sequence polymorphisms in two strains of Fasciola hepatica from Egypt and Europe
DNA sequence polymorphisms in two strains of Fasciola hepatica from Egypt and Europe.
Five samples each of European and Egyptian Fasciola hepatica of bovine origin were obtained and DNA was isolated.
The target of the PCR primers was a fragment of approximately 600 nucleotides in length corresponding to a region of the 18 S rRNA gene.
www.egeinfonet.i8.com /pub/2000/5.html   (196 words)

  
 Hepatica - Search Results - ninemsn Encarta
Hepatica, common and scientific name for a genus of perennial herbs, sometimes called liverleaf (see Buttercup).
Scientific classification: Flukes make up the class Trematoda.
The sheep-liver fluke is classified as Fasciola hepatica.
au.encarta.msn.com /Hepatica.html   (85 words)

  
 Ionic mechanisms underlying spontaneous muscle contractions in the liver fluke, Fasciola hepatica -- Graham et al. 277 ...   (Site not responding. Last check: 2007-11-04)
Ionic mechanisms underlying spontaneous muscle contractions in the liver fluke, Fasciola hepatica -- Graham et al.
Forskolin activation of serotonin-stimulated adenylate cyclase in the liver fluke, Fasciola hepatica.
The effect of serotonin (5-hydroxytryptamine) on the formation of adenosine 3',5'-phosphate by tissue particles from the liver fluke, Fasciola hepatica.
ajpregu.physiology.org /cgi/content/full/277/2/R374   (4941 words)

  
 Hepatica - [Grow Illini!] hepatica
An in-depth description of the sharp-lobed hepatica, including identifying characteristics, landscape use, and history.
Fasciola hepatica, Fasciola gigantica - Material Safety Data
Fasciola hepatica is found in parts of the United States (view distribution), Another example of a Fasciola hepatica egg, showing the operculum.
informationrun.com /?q=hepatica   (137 words)

  
 Allison C. Rice-Ficht   (Site not responding. Last check: 2007-11-04)
The viteline globules precursors to the shell are srongly positive.
Waite, J.H. and Rice-Ficht, A.C. (1989) "A Histidine-Rich Protein from the Vitellaria of the Liver Fluke Fasciola hepatica." Biochemistry, 28:6104-6110.
Rice-Ficht, A.C. (1992) "Composition and Design of Fasciola hepatica Eggshells." in "Results and Problems in Cell Differentiation: Structure, Cellular Synthesis and Assembly of Biopolymers".
pauling.tamu.edu /medbiogen/faculty/arf.html   (835 words)

  
 The pathogenesis of primary and secondary infection with Fasciola hepatica in mice -- Masake et al. 15 (6): 763 -- ...
The pathogenesis of primary and secondary infection with Fasciola hepatica in mice -- Masake et al.
The pathogenesis of primary and secondary infection with Fasciola hepatica in mice
Primary and secondary infections of F. hepatica in mice were compared to
www.vetpathology.org /cgi/content/abstract/15/6/763   (185 words)

  
 Thioredoxin Peroxidase Secreted by Fasciola hepatica Induces the Alternative Activation of Macrophages -- Donnelly et ...   (Site not responding. Last check: 2007-11-04)
The role of pulmonary cellular reactions in the resistance of vaccinated mice to Schistosoma mansoni.
Induction of protective immunity in cattle against infection with Fasciola hepatica by vaccination with cathepsin L proteinase and with hemoglobin.
Fasciola hepatica infection downregulates Th1 responses in mice.
iai.asm.org /cgi/content/full/73/1/166   (5246 words)

  
 eMedicine - Fascioliasis : Article Excerpt by: Robert W Tolan, Jr, MD   (Site not responding. Last check: 2007-11-04)
Synonyms, Key Words, and Related Terms: fascioliasis, Fasciola hepatica, Fasciola gigantica, halzoun (Lebanese), sheep liver fluke, liver fluke, marrerra (Sudanese), parasitic infection, sheep liver fluke disease, Fh, Fg
Background: Fascioliasis is an infection caused by flukes of the class Trematoda, most often characterized by fever, eosinophilia, and abdominal pain, although as many as half of these patients may be asymptomatic.
Humans are incidental hosts for Fasciola hepatica (Fh), commonly known as the sheep liver fluke, and Fasciola gigantica (Fg); these flukes cause similar illnesses in those who become infected by ingesting contaminated watercress or water.
www.emedicine.com /ped/byname/fascioliasis.htm   (619 words)

  
 eMedicine - Fascioliasis : Article by Robert W Tolan, Jr, MD   (Site not responding. Last check: 2007-11-04)
Graham CS, Brodie SB, Weller PF: Imported Fasciola hepatica Infection in the United States and Treatment with Triclabendazole.
Tantrawatpan C, Maleewong W, Wongkham C: Serodiagnosis of human fascioliasis by a cystatin capture enzyme-linked immunosorbent assay with recombinant fasciola gigantica cathepsin L antigen.
Walker SM, McKinstry B, Boray JC: Response of two isolates of Fasciola hepatica to treatment with triclabendazole in vivo and in vitro.
www.emedicine.com /ped/topic760.htm   (3202 words)

  
 A Light and Electron Microscope Study of the Epithelial Cells of the Gut of Fasciola hepatica L -- Gresson and ...   (Site not responding. Last check: 2007-11-04)
A Light and Electron Microscope Study of the Epithelial Cells of the Gut of Fasciola hepatica L -- Gresson and Threadgold 6 (2): 157 -- The Journal of Cell Biology
A Light and Electron Microscope Study of the Epithelial Cells of the Gut of Fasciola hepatica L
The structure of the epithelial cells of the alimentary tract
www.jcb.org /cgi/content/abstract/6/2/157   (249 words)

  
 Veterinary Parasites Review: Plasmodium, Eimeria, Cryptosporidium, Babesia, Neospora, Fasciola hepatica   (Site not responding. Last check: 2007-11-04)
A longstanding collaboration involving our group and the School of Biotechnology, DCU, has resulted in significant progress being made towards the development of vaccines to protect cattle and sheep against fascioliasis.
More recently, this work has been complemented by studies on the immunomodulating properties of Fasciola hepatica, how the parasite forces the immune system into mounting non-protective responses, and the implications this may have on the course of bacterial and viral infections in animals with fascioliasis.
We have also been funded to develop diagnostic assays for measurement of Fasciola-specific antibodies in humans.
www.ucd.ie /vetmed/html/research/summary/parasites.htm   (752 words)

  
 Sheep Liver Fluke (Fasciola Hepatica) ~ Trematoda ~ Platyhelminthes ~ Nasco
Sheep Liver Fluke (Fasciola Hepatica) ~ Trematoda ~ Platyhelminthes ~ Nasco
Note: This product may be eligible for special bulk or group discounts.
Orders from outside the United States may be charged additional distributor, customs, and shipping charges.
www.enasco.com /dissection/ProductDetail.do?sku=LS01283MH   (87 words)

  
 Australia.Merial.com : Producers : Sheep : Disease Information   (Site not responding. Last check: 2007-11-04)
Home > Producers > Sheep > Disease Information > Fasciola
Fasciola gigantica are 25 to 75mm by 5 to 12mm.
Adult flukes in liver lay eggs in bile which carries them into the intestine.
au.merial.com /producers/sheep/disease/fasci.html   (454 words)

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