| | New school of fish: solid tumor testing - College of American Pathologists (Site not responding. Last check: 2007-10-13) |
 | | Using FISH probes to detect recurrent UC in the urine relies on the fact that urothelial cells, especially UC cells, readily exfoliate and that UC cells, even from low-grade tumors, have a high frequency of chromosomal abnormalities. |
 | | By using FISH probes to determine whether the genetic pattern of tumor cells in sentinel lymph node matches the primary tumor, and then monitoring clinical outcomes, Dr. Tsongalis and his coworkers hope to answer these questions. |
 | | Because FISH assays can be applied to just about any type of cytologic specimen, Dr. Halling believes that cytologists and cytopathologists will be increasingly involved in performing and interpreting these tests, rather than the molecular diagnostics laboratory. |
| www.cap.org /apps/docs/cap_today/cover_stories/0104NewSchoolOfFISH.html (4401 words) |