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| | Fluorouracil |
 | | Stable in D5LR, D5W, NS; concentrations >25 mg/mL of fluorouracil and >2 mg/mL of leucovorin are incompatible (precipitation occurs). |
 | | A pyrimidine antimetabolite that interferes with DNA synthesis by blocking the methylation of deoxyuridylic acid; fluorouracil inhibits thymidylate synthetase (TS), or is incorporated into RNA. |
 | | Kuhn JG, "Fluorouracil and the New Oral Fluorinated Pyrimidines," Ann Pharmacother, 2001, 35(2):217-27. |
| www.umm.edu /altmed/drugs/fluorouracil-055400.htm (1410 words) |
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