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Topic: Jacob, Francois


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  François Jacob - Wikipedia, the free encyclopedia
François Jacob (born June 17, 1920 in Nancy, France) is a French biologist, who together with Jacques Monod, originated the idea that control of enzyme levels in all cells happens through feedback on transcription.
In around 1961 Jacob and Monod explored the idea that the control of enzyme expression levels in cells is a result of feedback on the transcription of DNA sequences.
Jacob and Monod somewhat recklessly extended this repressor model to all genes in all organisms, in their initial exuberance.
en.wikipedia.org /wiki/Francois_Jacob   (668 words)

  
 Francois Jacob - MSN Encarta
In 1961 Jacob and his Pasteur Institute colleague Monod described the operon model of gene regulation in one of the milestone papers of molecular biology.
Jacob and Monod saw in their model an explanation for why some cancers caused by viruses are activated after being dormant in the body.
Jacob and French bacteriologist Elie Wollman, also of the Pasteur Institute, showed that genetic recombination and replication occur in a similar manner in both bacteria and in humans.
encarta.msn.com /encyclopedia_761582623/Francois_Jacob.html   (413 words)

  
 BookRags: François Jacob Biography
Jacob was born in Nancy, France, to Simon Jacob, a merchant, and the former Thérèse Franck.
Jacob continued his education at the University of Paris during his first years at the Pasteur Institute, earning his bachelor of science in 1951 and studying toward his doctor of science degree, which he received in 1954.
In the experiments conducted by Jacob and Monod, the inducer, lactose, served to inhibit the gene that was regulating the synthesis of galactosidase.
www.bookrags.com /biography/francois-jacob-wmi   (1565 words)

  
 Francois Jacob
Francois Jacob was born in Nancy, France on June 17, 1920.
In 1965, Jacob received the Nobel Prize for Medicine, along with Jacques Monod and André Lwoff, for their research on the idea that control of enzyme levels in all cells happens through feedback on transcription.
Jacob and Monod made key experimental and theoretical discoveries that demonstrated that in the case of the lactose system outlined above (in the bacterium E. coli), there are specific proteins that are devoted to repressing the transcription of the DNA to its product (RNA, which in turn is decoded into protein).
www.jewishvirtuallibrary.org /jsource/biography/Francois_Jacob.html   (572 words)

  
 Geona.com - jacob - English Explanatory Dictionary   (Site not responding. Last check: 2007-11-01)
Laban would not consent to give him his daughter in marriage till he had served seven years; but to Jacob these years "seemed but a few days, for the love he had to her." But when the seven years were expired, Laban craftily deceived Jacob, and gave him his daughter Leah.
In this mysterious contest Jacob prevailed, and as a memorial of it his name was changed to Israel (wrestler with God); and the place where this occured he called Peniel, "for", said he, "I have seen God face to face, and my life is preserved" (32:25-31).
Jacob was soon after this deeply grieved by the loss of his beloved son Joseph through the jealousy of his brothers (37:33).
www.geona.com /dictionary?q=jacob   (1236 words)

  
 1961 - François Jacob & Jacques Monod & Marshall Nirenberg
Jacob and Wollman also studied conjugation in bacteria, the process by which genetic material is transferred from one cell to another.
In 1960 Jacob and Monod proposed the existence of the operon, consisting of an operator gene and structural genes that code for the enzymes needed in a given biosynthetic pathway.
Jacob and Monod received the 1965 Nobel Prize for physiology or medicine for this research, sharing the award with Lwoff.
www.laskerfoundation.org /news/gnn/timeline/1961a.html   (440 words)

  
 Jacob - Search Results - MSN Encarta
Jacob, in the Old Testament, one of the Hebrew patriarchs, son of Isaac and Rebekah, and grandson of Abraham.
Jacob, Max (1876-1944), French writer and painter, born in Quimper.
He tricked his older brother, Esau, out of his father's blessing, and had a vision of ascent into heaven that came to be called "Jacob's ladder"Genesis 25-35.
ca.encarta.msn.com /Jacob.html   (159 words)

  
 François Jacob - Biography
François Jacob was born in June 1920 in Nancy (France).
In 1947 François Jacob married the pianist Lise Bloch.
François Jacob is a member of the Académie des Sciences, Paris (1977) and of the Académie Française, Paris (1996).
nobelprize.org /nobel_prizes/medicine/laureates/1965/jacob-bio.html   (936 words)

  
 Genealogy   (Site not responding. Last check: 2007-11-01)
Francois DUPONT was born on 13 Jan 1769 in Ref. Kirke, Fredericia, Vejle, Danmark.
Francois DUPONT was born on 17 Nov 1806.
Francois Leon DUPONT was born on 28 Dec 1882.
home5.inet.tele.dk /koudal/slaegt/d132.htm   (1314 words)

  
 [No title]
Jacques Monod and Francois Jacob were the first to discover how genes were turned on and off.
Jacob served in North Africa and participated in the invasion of Normandy in 1944.
After Jacob realized that they were actually studying the same thing - repression - Jacob and Monod began their Nobel Prize-winning collaboration, uncovering the switch that turns beta-galactosidase synthesis off and on.
www.dnaftb.org /dnaftb/concept_33/con33bio.html   (962 words)

  
 DOGGETT-JACKSON
She was born in 1830 in St. Francois County, Missouri and was the daughter of Rhoda Doggett and William Jackson.
JACOB DOGGETT: Was born circa 1770 in Pittsylvania County, Virginia and was the son of Miller Doggett the Revalutionary War soldier.
Jacob's wife was named Susannah and they were the parents of four children: the first two names are unknown; then Mary; Olivia.
www.carrollscorner.net /DOGGETT-JACKSON.htm   (1431 words)

  
 Amazon.de: Of Flies, Mice and Men: English Books: Francois Jacob   (Site not responding. Last check: 2007-11-01)
Not many scientists are comfortable quoting poets from Sophocles to Apollinaire, but Jacob weaves their words with his own beautiful prose to inspire the reader with new ways of thinking about science as a part of human life.
Jacob is one of the few scientists who recognise that science is easily abused, but that its course can't be stopped, or even slowed much.
Also, Jacob, as a research scientist, understandably seems to feel the need to quote someone to corroborate everything he says, which means that the book quotes nearly everyone who's name is known, and these quotations lack relevance and insight most of the time.
www.amazon.de /Flies-Mice-Men-Francois-Jacob/dp/0674005384   (736 words)

  
 James Brody: The French Evolution: A review of Of Flies, Mice, and Men by François Jacob
François Jacob and Jacques Monod shared the Nobel Prize for Medicine in 1965 for their work on the regulator sequences in genes.
Jacob’s text, a collection of seven lectures, is itself a combinatorial mosaic and models the very processes that he describes.
Jacob’s view implies that traditional biologists must retool their thinking; these newer ideas also give some of us outside of biology a chance to get in the door.
human-nature.com /nibbs/03/jacob.html   (1750 words)

  
 MIND/BODY/HEALTH; The Scientist as Ignoramus and Hero - New York Times
Jacob has written an autobiography that is not only literate but positively literary, shot through with reminiscences of classical French authors, skillfully plotted and elegantly written.
Jacob's narrative, translated by Franklin Philip, is wholly accessible to the reader whose biology is at most a vague memory from high school.
Jacob so often had the good fortune to be in the right place at the right time - and the intelligence and courage to make the right choices, even at times when many others were choosing wrong.
query.nytimes.com /gst/fullpage.html?res=940DE7DD173FF934A15750C0A96E948260   (503 words)

  
 Jacob, Francois. The Columbia Encyclopedia, Sixth Edition. 2001-05
He shared the 1965 Nobel Prize in Physiology or Medicine with André Lwoff and Jacques Monod for work in genetics, especially his proposal, with Monod, of a mechanism for the regulation of the expression of genes.
Jacob and Monod coined the term messenger RNA.
Jacob’s writings include The Logic of Life: A History of Heredity (1974).
www.bartleby.com /65/ja/Jacob-Fr.html   (161 words)

  
 Jacob, François   (Site not responding. Last check: 2007-11-01)
Jacob was born in Nancy and studied at the University of Paris.
Jacob began his work on the control of gene action in 1958, working with Lwoff and Monod.
It was known that the types of proteins produced in an organism are controlled by DNA, and Jacob focused his research on how the amount of protein is controlled.
www.cartage.org.lb /en/themes/Biographies/MainBiographies/J/Jacob/1.html   (173 words)

  
 Jacob
In exchange for a bowl of lentil soup, Jacob obtained Esau's birthright and, with his mother's help, received the blessing that the dying Isaac had intended for his older son.
Jacob died there, but his sons buried him in the family plot at Machpelah.
François Jacob - Jacob, François, 1920–, French biologist, educated at the Sorbonne.
www.infoplease.com /ce6/people/A0825829.html   (315 words)

  
 Ancestors of John Crossley
Francois Jacob died on 21 Feb 1764 in Saverne, Bas-Rhin, France.
On 17 Nov 1721 Francois Jacob married Elisabeth Kress, in Uhlwiller, Bas-Rhin, France.
Jacob died in Marmoutier, Bas-Rhin, France, on 6 Mar 1777; he was 77.
homepage.mac.com /jcrossley/at/at01/at01_010.htm   (300 words)

  
 Jacques Monod - Wikipedia, the free encyclopedia
Monod (along with François Jacob) is famous for his work on the Lac operon.
Monod also made important contributions to the field of enzymology with his proposed theory of allostery proposed in 1965.
The experimental system used by Jacob and Monod was a common bacterium, E.
en.wikipedia.org /wiki/Jacques_Monod   (391 words)

  
 Factmonster Search: jacob
Jacob, in the Bible, ancestor of the Hebrews, the younger of Isaac and Rebecca's twin sons; the...
Jacob, François, 1920–, French biologist, educated at the Sorbonne.
Jacobs, Joseph, 1854–1916, Jewish writer, historian, and folklorist, b.
www.factmonster.com /search?fr=fmtn&x=0&y=0&query=Jacob   (108 words)

  
 Bio 4V00   (Site not responding. Last check: 2007-11-01)
Chapeville, Francois, Fritz Lipmann, Gunter von Ehrenstein, Bernard Weisblum, William J. Ray, Jr., and Seymour Benzer 1962, Proceedings of the National Academy of Sciences, USA, 48, 1086-1092.
Jacob, Francois, David Perrin, Carmen Sanchez and Jacque Monod 1960, Compte Rendus des Seances de l’Academie des Sciences, 250, 1727-1729.
Jacob, Francois and Jacque Monod 1961 Genetic regulatory mechanisms in the synthesis of proteins.
nsm1.utdallas.edu /bio/Cirillo/Syllabi/Bio4337SP01.htm   (630 words)

  
 ORNL's Unsung Discovery
The discovery, for which Jacob and Monod received a Nobel Prize, was "next to the original discovery of the molecular structure of DNA, probably the most important event in the history of molecular biology," Weinberg says.
These were precisely the properties that Jacob and Jacques Monod sought to assign to the unstable intermediate (which they called X), necessary for the synthesis of galactosidase.
In 1965 French scientists Monod, Jacob, and Andre Lwoff received the Nobel Prize in Physiology or Medicine for elucidating the nature of mRNA from their observation of protein synthesis by genes of mutated bacteria in the presence of lactose.
www.ornl.gov /info/ornlreview/v37_3_04/article12.shtml   (1348 words)

  
 BookRags: François Jacob Biography
François Jacob was born in June 1920 in Nancy, Meurthe-et-Moselle, France.
To explain how the bacteria regulate enzyme production, Jacob (with Andre Lwoff and Jacques Monod) theorized that there are three types of genes, a gene being a deoxyribonucleic acid (DNA) triplet or triplet cluster.
An operon is a gene cluster composed of two types of genes: Z (structural) genes, which carry the instructions for protein production, such as for the -galactosidase, and O (operator) genes, which control whether the Z genes' instructions are carried to the cell's ribosomes for protein production.
www.bookrags.com /biography/francois-jacob-woh   (349 words)

  
 BookRags: François Jacob Biography
For his doctoral dissertation, Jacob reviewed the ability of certain radiations or chemical compounds to induce the prophage, and proposed possible mechanisms of immunity.
The two scientists also discovered and defined episomes, genetic strains which automatically replicate as part of the development of chromosomes.
Within two years Jacob began to work with Jacques Monod, who had left Lwoff's lab several years earlier to direct the department of cellular biochemistry at the Pasteur Institute.
www.bookrags.com /biography/francois-jacob-wog   (1562 words)

  
 Francois Jacob Books - Signed, used, new, out-of-print
In "The Logic of Life" Francois Jacob looks at the way our understanding of biology has changed since the sixteenth century.
In a new preface to this special edition of his critically acclaimed memoir, Francois Jacob recalls the events that brought him to Cold Spring Harbor Laboratory in the early 1960's and taught him much about phage biology and the informal ways of American science.
The complete works of Doctor Francois Rabelais, abstractor of the quintessence: being an account of the inestimable life of the great Gargantua, and of the heroic deeds, sayings and marvellous voyages of his son the good Pentagruel:
www.alibris.com /search/books/author/Francois_Jacob   (445 words)

  
 Francois-honore-georges Jacob-desmalter ( - ) Artwork Images, Exhibitions, Reviews
Jacob van der Ulft, A Triumph in Ancient Rome, 17th century
Francois Bonvin, Francois Bonvin gravant a l"eau forte, 1861
Francois-Guillaume Menageot - The Death of Leonardo da Vinci in the Arms of Francois I c.
wwar.com /masters/j/jacob-desmalter-francois-honore-georges.html   (430 words)

  
 Of Flies, Mice, and Men by François Jacob, Giselle Weiss(Translator), New, Used Books, Cheap Prices, ISBN 0674631110
Of Flies, Mice, and Men is at once a work of history, a social study of the role of scientists in the modern world, and a cautionary tale of the bumbling and brilliance, imagination and luck, that attend scientific discovery.
In particular, Jacob scrutinizes the place of the scientist in society.
And the crucial truth that molecular biology teaches is the one he elaborates with great clarity and grace in this book: that all animals are made of the same building blocks, by a combinatorial system that always rearranges the same elements according to new forms.
www.bookfinder4u.com /detail/0674631110.html   (804 words)

  
 Jacob, F.; Spillmann, B.E., trans.: The Logic of Life: A History of Heredity.
Jacob, F.; Spillmann, B.E., trans.: The Logic of Life: A History of Heredity.
He describes four fundamental turning points in the perception of the structure of living things: the discoveries of the functions of organs, cells, chromosomes and genes, and DNA.
"François Jacob, who won the Nobel Prize in 1965 for his work on genetics, has written an unusual and illuminating history of his discipline.
www.pup.princeton.edu /titles/5200.html   (255 words)

  
 Francois Jacob Winner of the 1965 Nobel Prize in Medicine
Francois Jacob Winner of the 1965 Nobel Prize in Medicine
Francois Jacob Lewis Thomas Prize 1994 (submitted by Patrick Bertranou MD)
Francois Jacob Nobel lecture (submitted by george swaneck)
almaz.com /nobel/medicine/1965a.html   (80 words)

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