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	1869 - Johann Friedrich Miescher
		Miescher himself studied medicine at Basel but, feeling that his partial deafness (produced by a severe attack of typhus) would be a drawback for a physician, turned to physiological chemistry.
		Miescher was soon able to show that nuclein could be obtained from many other cells and was unusual in containing phosphorus in addition to the usual ingredients of organic molecules - carbon, oxygen, nitrogen, and hydrogen.
		Miescher continued to work on the nuclein extracted from the sperm of the Rhine salmon for the rest of his short life.
	www.laskerfoundation.org /rprimers/gnn/timeline/1869a.html (451 words)

	Friedrich Miescher - Wikipedia, the free encyclopedia
		Johan Friedrich Miescher (13 August 1844 - 26 August 1895) was a biologist born in Basel.
		Miescher was interested in studying the chemistry of the nucleus.
		The importance of Mieschers discovery was not apparent until Albrecht Karl Ludwig Martin Leonard Kossel a German physiologist specializing in the physiological chemistry of the cell and its nucleus and of proteins carried out research on the chemical structure of nuclein.
	en.wikipedia.org /wiki/Friedrich_Miescher (580 words)

	[No title]
		In 1869, Friedrich Miescher isolated "nuclein," DNA with associated proteins, from cell nuclei.
		Friedrich (Fritz) Miescher was born in Basel, Switzerland.
		In 1872, Miescher was appointed the professor of physiology at the University of Basel, a position previously held by his father and then his uncle.
	www.dnaftb.org /dnaftb/concept_15/con15bio.html (841 words)

	Biology 3202AP GrassRoots (Site not responding. Last check: 2007-10-10)
		Friedrich Miescher was born in Basel on August 13th, 1844.
		Miescher himself studied medicine at Basel but, feeling that his partial deafness would be a drawback for a physician, turned to physiological chemistry.
		Miescher continued to work on the nuclein extracted from the sperm of the Rhine salmon for the remainder of his life.
	www.hhm.k12.nf.ca /parsonsbio/fredrich.html (468 words)

	Friedrich Miescher Summary
		Miescher himself studied medicine at the University, but decided to study chemistry instead because he was concerned that his partial deafness, caused by an earlier bout with typhus, would impair his ability as a physician.
		Friedrich then went onto to study physiology at Leipzig in the laboratory of Carl Ludwig for a year before returning to Basel where he was appointed professor of physiology.
		The importance of Mieschers discovery was not apparent until Albrecht Karl Ludwig Martin Leonard Kossel a German physiologist specializing in the physiological chemistry of the cell and its nucleus and of proteins carried out research on the chemical structure of nuclein.
	www.bookrags.com /Friedrich_Miescher (1092 words)

	FML - Biography of Friedrich Miescher (1844-1895) (Site not responding. Last check: 2007-10-10)
		You are here: Home » Biography of Friedrich Miescher (1844-1895)
		Friedrich Miescher was born in Basel on August 13th, 1844.
		Friedrich Miescher Laboratory of the Max Planck Society, Spemannstraße 35, 72076 Tübingen, Germany
	www.fml.tuebingen.mpg.de /miescher.htm (100 words)

	genome.gov \| ONLINE Education Kit - 1869
		Friedrich Miescher isolates DNA for the first time.
		He chose to study white blood cells, which are abundant in pus, and were abundantly available to him in bandages from a hospital near his university.
		Miescher isolated a material rich in phosphorus from the cells and called it nuclein.
	www.genome.gov /Pages/Education/Kit/main.cfm?pageid=19 (90 words)

	BIOdotEDU
		In 1865, the year that Gregor Mendel ("Brother Gregory" in these stories) published his paper on the hybridization of plants, and thus started the science of heredity and genetics, the University of Tubingen took a bold educational step and became the first Germany University to start a department of "natural science".
		Miescher, in his own words "was fascinated by the thought of tracing the most generally valid conditions of cell life from the simplest and independent forms of animal cells".
		After checking Miescher's results, and extending the discovery of nuclein to other substances, a paper announcing it's discovery was finally published in 1871.
	www.brooklyn.cuny.edu /bc/ahp/LAD/C4/C4_Discovery.html (409 words)

	Friedrich Miescher's laboratory, 1879, still image (Site not responding. Last check: 2007-10-10)
		Miescher was interested in cells, which were visible through a new invention, the microscope.
		As a doctor, Miescher had a ready supply of white blood cells, from the pus-filled bandages at the hospital where he worked.
		Miescher added some simple chemicals to these cells and isolated a white precipitate he called "nuclein." Miescher assumed, correctly, that the precipitate was from the large nuclei of the white blood cells.
	www.dnai.org /text/754_friedrich_mieschers_laboratory_1879_still_image.html (95 words)

	Landmarks in the History of Genetics
		Miescher discovers "nuclein" (DNA) in the cells from pus in open wounds -- cells composed mostly of nuclear material.
		Miescher's 1869 work was not published until 1871 (Dictionary of Scientists, 1999).
		Johann Friedrich Miescher (1844-1895; see external portrait) was a Swiss student of cell metabolism.
	cogweb.ucla.edu /ep/DNA_history.html (1474 words)

	Eu- and Heterochromatin (Site not responding. Last check: 2007-10-10)
		In the late 1860's, Friedrich Miescher isolated, from homogenates of lymph and pus cells, material that had the staining and shrinking-swelling properties of nuclei.
		Miescher's work leads to the view that the nuclear material consists of DNA and protein.
		Miescher's isolation led to the chemical characterization of DNA by many workers including Kossel and Levene.
	opbs.okstate.edu /~melcher/MG/MGW1/MG1131.html (318 words)

	ion channel jobs - Postdoctoral Position - Friedrich Miescher Institute - Basel, Switzerland (Site not responding. Last check: 2007-10-10)
		Description: Friedrich Miescher Institute Postdoctoral Position Friedrich Miescher Institute FMI Postdoctoral Position in Neurophysiology Applications are invited for a postdoctoral fellowship in the group of Prof.
		The Friedrich Miescher Institute, part of the Novartis Research Foundation, is an international biomedical research centre with 280 members, including 180 postdoctoral fellows and graduate students, pursuing basic problems in biomedical research.
		The Friedrich Miescher Institute is situated in Basel, a city in the centre of Europe offering an outstanding scientific and cultural environment.
	www.ionchannels.org /showcareer.php?jobid=62 (288 words)

	National Centre for Biotechnology Education \| DNA50 \| Pea DNA
		After several months of toil in a laboratory in the cellar of Tübingen Castle, Miescher managed to isolate a previously-unknown acidic substance from white blood cells (leucocytes) washed from pus-laden bandages donated by a nearby hospital.
		Miescher called his discovery 'nuclein' because it was found in the nuclei of the cells.
		Upon returning to his home in Basel in 1870, Miescher refined the method and was able to extract nuclear material from the sperm of the salmon for which, in those days, the Rhine was famed.
	www.ncbe.reading.ac.uk /DNA50/peadna.html (1458 words)

	The Search for DNA - The Birth of Molecular Biology
		The history of deoxyribonucleic acid (DNA) research begins with Friedrich Miescher, a Swiss biologist who in 1868 carried out the first carefully thought out chemical studies on the nuclei of cells.
		Using the nuclei of pus cells obtained from discarded surgical bandages, Miescher detected a phosphorus-containing substance that he named nuclein.
		Even though Miescher and many others following him suspected that nuclein or nucleic acid might play a key role in cell inheritance, others argued that their lack of chemical diversity compared to, say, proteins ruled out such a possibility.
	www.accessexcellence.org /AB/BC/Search_for_DNA.html (1022 words)

	DNA and proteins are the molecules of the cell nucleus.
		By the early 1900's, we knew that Miescher's nuclein was a mix of proteins and nucleic acids.
		The lab was run by Felix Hoppe-Seyler, and located in the vaults of an old castle.
		Located in Basel, Switzerland, the FMI was founded in 1970 and named in honor of Friedrich Miescher.
	www.bioservers.org /dnaftb/text/15 (2208 words)

	Unlocking the Secrets of Science (Site not responding. Last check: 2007-10-10)
		It wasn’t until a shy young Swiss chemist stumbled upon a new substance that the mystery began to be literally unraveled.
		Friedrich Miescher came from a distinguished family of physicians but turned to research for his life’s work, worried that a hearing impairment would make it difficult to treat patients properly.
		Although Miescher would discover the key to heredity, nucleic acid, it would be many years before the importance of his discovery was fully appreciated.
	www.mitchelllane.com /uuu_files/uuu.html (3546 words)

	Re: What is RNA in terms that I can understand?
		However, in 1869, a Swiss biochemist, Johann Friedrich Miescher (1844 - 1895) was able to isolate a substance from the remnants of cells in pus that did not belong to any of these three classes.
		Miescher took his new discover to fellow biochemist, Felix Hoppe-Seyler who independently investigated the matter.
		That is, Miescher and Hoppe-Seyler had isolated and characterized a fragment of a cell that appeared to be associated with the nucleus, appeared to be an acid, and appeared to not be any of the previously identified cellular fragments.
	www.madsci.org /posts/archives/1999-04/924579397.Bc.r.html (530 words)

	Biology (Site not responding. Last check: 2007-10-10)
		In 1868 while performing experiments to identify the chemical composition of the cell’s nucleus, a physician, Johann Friedrich Miescher, isolated an organic compound with the properties of an acid.
		Miescher’s work was the historical beginning of everything we now know about DNA.
		The process of DNA extraction and isolation is not just an historical milestone in science; even today, it must be performed as the first step in any DNA analysis.
	www.punahou.edu /acad/biology/hodges/DNAExtraction.html (572 words)

	OHSU News Release
		The conclusions of this study are printed in the June 16 edition of the journal Science.
		Swiss collaborators for the study included researchers from the Friedrich Miescher Institute, the University of Zurich and the University of Basel.
		To study the role of the S6 gene, scientists at the Friedrich Miescher Institute developed a mutant mouse lacking the S6 gene.
	www.ohsu.edu /unparchive/2000/061500ribosome.html (518 words)

	Research Technician
		The Friedrich Miescher Institute is an international biomedical research centre with 250 members pursuing basic problems in biomedical research.
		The FMI is part of the Novartis Research Foundation and is situated in Basel.
		Please send full particulars to Human Resources, Friedrich Miescher Institute, Maulbeerstrasse 66 (R-1066.5.54), 4058 Basel, Switzerland or by e-mail to hr@fmi.ch.
	elegans.swmed.edu /Announcements/grosshans_tech.htm (289 words)

	New director at the Friedrich Miescher Institutes - Novartis.com (Site not responding. Last check: 2007-10-10)
		Susan Gasser, Professor for Molecular Biology at the University of Geneva, has been named the new director of the Friedrich Miescher Institute (FMI) in Basel.
		Next to the Friedrich Miescher (FMI) in Basel, the corporate research institutes are: The Genomics Institute of the Novartis Research Foundation (GNF) in La Jolla, California and The Novartis Institute for Tropical Diseases (NITD) in Singapore.
		The GNF was founded in 1999 and is funded through the Novartis Research Foundation as a research center focused on genomics and proteomics.
	www.novartis.com /special/fmi_newdirector.shtml (554 words)

	Friedrich Miescher: bio and encyclopedia article (Site not responding. Last check: 2007-10-10)
		The updated page can be found at: friedrich miescher
		Johan Friedrich Miescher (13 August 1844 - 26 August 1895) was a biologist (biologist: (biology) a scientist who studies living organisms) born in Basel (Basel: A city in northwestern Switzerland).
		The significance of the discovery, first published in 1871, was not at first apparent, and it was Albrecht Karl Ludwig Martin Leonard Kossel (Albrecht Karl Ludwig Martin Leonard Kossel: more facts about this subject) who made the initial inquiries into its chemical structure.
	www.absoluteastronomy.com /reference/friedrich_miescher (97 words)

	The Double Helix (Site not responding. Last check: 2007-10-10)
		The first important step toward a reductionist understanding of the inheritance of traits in living creatures was made by the Swiss biochemist, Friedrich Miescher, in 1869.
		Although Miescher's original formula was a little too high in hydrogen and oxygen and a little too low in nitrogen, it was remarkably accurate for 1869.
		Although Miescher's material was an acid, many chemists believed it looked suspiciously like a protein needing only a little more purification.
	www.truertru.com /articles/helix.htm (6149 words)

	Mechanism of Activation of NDR (Nuclear Dbf2-related) Protein Kinase by the hMOB1 Protein -- Bichsel et al. 279 (34): ...
		From the Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, CH-4058 Basel, Switzerland
		The Friedrich Miescher Institute is part of the Novartis Research
		To whom correspondence should be addressed: Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, CH-4058 Basel, Switzerland.
	www.jbc.org /cgi/content/abstract/279/34/35228 (478 words)

	Novartis Institute for Tropical Diseases -Corporate Research - NITD
		Paul Herrling, Ph.D. The other two Corporate Research institutes are the Friedrich Miescher Institute (FMI) in Basel, Switzerland, and the Genomics Institute of the Novartis Research Foundation (GNF) in La Jolla, California.
		The mission of the corporate research institutes is to leverage the specific scientific knowledge from its three institutes in order to contribute to Novartis' goal of addressing unmet medical needs.
		The Friedrich Miescher Institute (FMI) was founded in 1970, and is and is now part of the Novartis Research Foundation.
	www.nitd.novartis.com /corporate_research/index.shtml (403 words)

	Characterization of the interactions between mammalian PAZ PIWI domain proteins and Dicer (Site not responding. Last check: 2007-10-10)
		Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland
		Friedrich Miescher Institute for Biomedical Research, POB 2542 4002 Basel, Switzerland
		Friedrich Miescher Institute is a part of the Novartis Research Foundation.
	www.nature.com /embor/journal/v5/n2/full/7400070.html (3850 words)

	Forschungsperspektiven 2000plus: Biological research groups at the Friedrich-Miescher-Laboratory of the Max Planck ...
		Currently, research is being conducted in neurobiological and cell biological problems.
		The administrative and organizational interests of research groups at the Friedrich Miescher Laboratory are represented by one of the four group leaders.
		The interests as well as the actual premises of the laboratory are integrated into the campus of the Max Planck institute in Tübingen, permitting intensive scientific and methodological contact with neighboring institutes.
	2000plus.mpg.de /e/319/article (592 words)

	Sandra J. F. Degen, PhD, Cincinnati Children's Hospital Medical Center
		Sandra J. Degen, PhD, received her BA degree in Chemistry from the University of California, San Diego in 1976 and her PhD degree in Biochemistry from the University of Washington in 1982.
		Following a two year post-doctoral fellowship at the Friedrich Miescher Institute in Basel, Switzerland, she was appointed as an Assistant Professor of Pediatrics at the University of Cincinnati in 1985.
		Fellowship: Post-doctoral fellowship at the University of Washington in Seattle, Wash., 1982-83; post-doctoral Fellowship at the Friedrich Meischer Institute in Basel, Switzerland, 1983-1985.
	www.cincinnatichildrens.org /svc/find-professional/d/sandra-degen.htm (1362 words)

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