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| | FAQ: HFI Detailed |
 | | These repercussions of fructose ingestion are most dire for the newborn infant whose parents are unaware of the disorder and may coerce the persistent ingestion of fructose, making weaning during infancy the period of greatest risk. |
 | | Aldolase B is the major aldolase isozyme in the liver and functions in both fructose metabolism, using fructose 1-phosphate as a substrate, and in gluconeogenesis, producing fructose 1,6-bisphosphate from the two triose phosphates, glyceraldehyde-3-phosphate and dihydroxyacetone phosphate. |
 | | The treatment for HFI is the exclusion of fructose, sucrose, and sorbitol (less than 40 mg/kg per day) from the diet (3) and results in complete alleviation of most symptoms and a normal life span (1). |
| www.bu.edu /aldolase/HFI/hfiinfo/detail.html (1095 words) |
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