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Topic: Fusarium infections

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	Fusarium Species
		Fusarium is one of the emerging causes of opportunistic mycoses [61, 64, 525, 907, 1409, 1561, 1805, 1899, 2270, 2277].
		Fusarium infections following solid organ transplantation tend to remain local and have a better outcome compared to those that develop in patients with hematological malignancies and bone marrow transplantation patients [1992].
		Invasive infection with Fusarium chlamydosporum in a patient with aplastic anemia.
	www.doctorfungus.org /thefungi/fusarium.htm (2385 words)

	Fusarium (Site not responding. Last check: 2007-10-12)
		However, the duration from admission to infection in the patients with fusariosis tended to be shorter than the duration from admission to discharge in the exposed control patients (P =.06).
		Fusarium species are ubiquitous and may be found in the soil, air and on plants.
		Portals of entry of disseminated infection include the respiratory tract, the gastrointestinal tract, and cutaneous sites.The skin can be an important and an early clue to diagnosis since cutaneous lesions may be observed at an early stage of the disease and in about seventy-five cases of disseminated Fusarium infection.
	www.thedoctorsdoctor.com:16080 /diseases/fusarium.htm (2971 words)

	Mold Growth After Flooding Poses Health Hazard: Fusarium Infections in Critically Ill Patients
		Fusarium hyphae are subsequently destroyed extracellularly by the oxidative cytotoxic mechanisms of neutrophils.
		For example, Fusarium infections in solid-organ transplant recipients tend to remain localized, occur late in the posttransplant period (>9 months), and have a better outcome when compared with infections in allogeneic BMT recipients with graft-versus-host disease, which are characteristically disseminated and frequently fatal.
		In contrast with Fusarium infections in normal hosts, which are typically localized (e.g., skin and eye infections and osteomyelitis) and frequently do not require systemic therapy, fusariosis in profoundly immunocompromised patients manifests in four major patterns: refractory fever of unknown origin, sinopulmonary infection or pneumonia, disseminated infection, and a variety of focal single-organ infections.
	www.imakenews.com /pureaircontrols/e_article000328271.cfm?x=b11,0,w (6679 words)

	Food Research Institute Briefings: Fusarium Mycotoxins
		Fusaria cause diseases, such as ear rot in corn and head blight and scab in wheat, that affect growth and yield of crops and were estimated to cause a loss of a billion dollars to wheat farmers in the USA in 1993.
		At the Fifth European Fusarium Seminar, held in Hungary in August—September 1997, recent data on Fusarium infections in crops, the effects of Fusarium toxins on human and animal health, and different approaches to dealing with them were shared and discussed (1).
		Evidence is accumulating that infection rates are higher in crops planted in fields previously planted in corn, particularly when crop residues are left in the field.
	www.wisc.edu /fri/fusarium.htm (1844 words)

	[No title]
		Catheter-related Fusarium solani fungemia and pulmonary infection in a patient with leukemia in remission.
		Scand J Infect Dis 1994;26:225-8 Clinical data from 10 episodes of disseminated infection with Fusarium among eight recipients of bone marrow transplants and from 31 cases reported previously in the literature.
		Fusarium oxysporum causes surface rot of sweet potato tubers and has been found to be one of the agents that induces high concentrations (350 to 9,480 p.g/g) of ipomeamarone in infected sweet potato tissue, but not in surrounding healthy tissue (Martin et al., 1976).
	www.accionecologica.org /descargas/areas/fumigaciones_plancolombia/documentos/casos/fusarium/MYCOHE1.DOC (6153 words)

	Natamycin - Wikipedia, the free encyclopedia
		It is a macrolide polyene antifungal drug used to treat fungal keratitis.
		It is especially effective against Aspergillus and Fusarium corneal infections.
		It is used in the food industry as a preservative to inhibit fungal growth on cheese.
	en.wikipedia.org /wiki/Natamycin (146 words)

	Fusarium, a Significant Emerging Pathogen in Patients With Hematologic Malignancy: Ten Years' Experience at a Cancer ... (Site not responding. Last check: 2007-10-12)
		Infection documentation was obtained from the bloodstream of 18 patients and from the nails of five patients with onychomycoses and concomitant toe or finger cellulitis.
		Fusarium should also be considered in the differential diagnosis of invasive mold infections following engraftment in bone marrow transplant recipients, since fusarial infections may mimic aspergillosis, which is known to occur postengraftment in bone marrow transplant recipients (Fig 4).
		In conclusion, invasive fusarial infections represent an increasing cause of infectious morbidity and mortality in patients with hematologic cancer.
	www.bloodjournal.org /cgi/content/full/90/3/999 (6286 words)

	ECCMID: Posaconazole Promising as Alternative Therapy for Fusarium Infection
		infections is particularly challenging due to limited activity and resistance among the currently available drugs," explained Raul Herbrecht, a member of the research team.
		infections as a primary pathogen, were administered 800 mg/day of oral posaconazole in divided doses.
		In addition, the success rate was 40% in patients with refractory infections, and 62% in those with non-refractory infections.
	www.docguide.com /dg.nsf/PrintPrint/12773D4A0F119FBF85256E8A0048DB1C (413 words)

	Letter from Professor Posada to Juan MayrClick on thumbnails to expand. Right-click on expanded images to save.
		Fusarium is responsible for the vascular rot in vegetables, perennial ornamentals, herbs, plantations (banana, tomato, coffee, cotton, corn, potato, dates etc) and trees.
		Fusarium infection with unusual skin lesions in a patient with acute lymphocytic leukemia.
		Spielberger, R.T., Falleroni MJ, Coene AJ, 1993, Concomitant amphotericin B therapy, granulocyte transfusions, and GM_CSF administration for disseminated infection with Fusarium in a granulocytopenic patient Clin Infect Dis 16:528_530,.
	mycoherbicide.info /World-Regions/Colombia/Posada-Mayr/index.htm (1756 words)

	U.S. Pharmacist
		Fungal infections are a major cause of morbidity and mortality in immunocompromised patients.
		Suspicion for a fungal infection is increased when other types of infections, such as viral or bacterial, have been ruled out and the patient is known to have fungal colonization or suspicious radiographic findings.
		Fusarium infection in hematopoietic stem cell transplant recipients.
	www.uspharmacist.com /index.asp?show=article&page=8_1671.htm (3365 words)

	European Society of Clinical Microbiology and Infectious Diseases
		Fusarium is a genus of ubiquitous fungi that can cause life-threatening disseminated infections in severely compromised hosts.
		The overall success rates were 48% (11 of 23) for all infections and 36% (four of 11) for disseminated infections.
		The success rate was 40% (six of 15) in patients with refractory infections and 62% (five of eight) in patients with non-refractory infections.
	www.blackwellpublishing.com /eccmid14/abstract.asp?id=13939 (374 words)

	Agent Green: Risks of Using Biological Agents to Eradicate Drug Plants (Sunshine Project Backgrounder #14, September ...
		[76] Fusarium infections are especially dangerous and difficult to treat[77] as they disseminate easily due to the ability of the fungus to build new, infectious spores within the body.
		One theory holds that Fusarium infections are on the rise mainly because the number of risk patients with a compromised immune system has been increasing for the past two decades.
		(1997) Characterization of a vascular wilt of Erythroxylum coca caused by Fusarium oxysporum f.sp.
	www.sunshine-project.org /publications/bk/bk14.html (12328 words)

	Homo sapiens diseases - Fungi (Site not responding. Last check: 2007-10-12)
		Infections caused by A. ustus may be of particular concern, as the organisms exhibit low susceptibility to multiple antifungal drugs, and outcomes have been uniformly poor.
		polarization results in formation of granulomas, which is usually succesful at limiting the infection and preventing serious, disseminated disease : while the initial infection is contained, it does persist in the host in a dormant state within calcified granulomas and is capable of causing disease by reactivation if immunological dysfunction develops.
		It may be either a new infection or a reactivation of arrested primary disease, such as in immunocompromised patients.
	focosi.altervista.org /pathofungi.htm (4618 words)

	Letter from Professor Posada to Juan MayrClick on thumbnails to expand. Right-click on expanded images to save.
		Fungi of the Fusarium genus attack humans whose defense levels are low, causing diseases such as changes in the skin, keratitis, onychomycosis, arthritis and mycetomas.
		The death rate caused by Fusarium infections in humans is 76%.
		Fusarium oxysporum secretes toxins into the soil and into the plants that it attacks which are highly toxic to animal and human life.
	www.narconews.com /~myco/Mycoherbicide.info/World-Regions/Colombia/Posada-Mayr (1756 words)

	EyeWorld Magazine: July 2006
		Source: Francis Mah, M.D. usarium keratitis infections are quite uncommon in the United States because they thrive in tropical climates, but an April Centers for Disease Control and Prevention (CDC) report cited 109 cases under investigation in 17 states.
		Signs of a fungal infection that can be seen, however, might include satellite lesions in different spots around the cornea, along with feathery margins to the infiltrate, Dr. Mah said.
		If the infection looks very deep with a lot of inflammation, this also could be a fungus, he said.
	www.eyeworld.org /article.php?sid=3260 (951 words)

	Clinical and Epidemiological Aspects of Infections Caused by Fusarium Species: a Collaborative Study from Israel -- ...
		Fusarium wilt of crown rot of sweet basil: involvement of soilborne and airborne inoculum.
		Fungal infections in patients undergoing blood and marrow transplantation.
		Epidemiology and outcome of mould infections in hematopoietic stem cell transplant recipients.
	jcm.asm.org /cgi/content/full/42/8/3456 (2808 words)

	Singapore Eye Infections Heighten Contact Lens Co - Eye Disorders including cataracts, Lasik eye surgery, blindness, ... (Site not responding. Last check: 2007-10-12)
		Fusarium keratitis is usually a rare infection, but cases in Singapore have increased sharply since March 2005, according to doctors who wrote the new report.
		"By highlighting this series of Fusarium keratitis among contact lens wearers in Singapore, we hope to alert physicians and other eye care clinicians worldwide to maintain a high index of suspicion for fungal infection when evaluating and treating patients with contact lens-associated microbial keratitis," the researchers concluded.
		This increase in Fusarium keratitis infections is due to Bausch & Lomb's ReNu with MoistureLoc and to poor contact lens hygiene among patients, Cykiert said.
	www.medicinenet.com /script/main/art.asp?articlekey=62710 (1207 words)

	Parker & Waichman, LLP Files Suit Against Bausch & Lomb, Inc. on Behalf of Woman who Became Permanently Blind ...
		In this case, the injured woman, who resides in West Virginia, was diagnosed with a Fusarium fungal infection in her left eye after using ReNu with MoistureLoc(tm).
		Parker & Waichman, LLP has been retained by numerous individuals diagnosed with Fusarium keratitis and other fungal infections who suffer from impaired vision as a result of damage to their eyes caused by the infection.
		Fusarium keratitis is a severe infection of the cornea.
	www.emediawire.com /releases/2006/5/emw382030.htm (731 words)

	ECCMID: Posaconazole Promising as Alternative Therapy for Fusarium Infection (Site not responding. Last check: 2007-10-12)
		"The treatment of severe disseminated Fusarium infections is particularly challenging due to limited activity and resistance among the currently available drugs," explained Raul Herbrecht, a member of the research team.
		Twenty three patients, presenting with proven or probable Fusarium infections as a primary pathogen, were administered 800 mg/day of oral posaconazole in divided doses.
		Unspeciated Fusarium was present in 18 of the patients.
	www.pslgroup.com /dg/24401e.htm (413 words)

	Contact Lenses and Eye Infections
		FDA continues to work with the CDC to investigate the Fusarium keratitis infections and will determine whether or not further action needs to be taken.
		Because of the nature of the organism (Fusarium), extensive microbiological testing is being conducted and may take up to one month to fully analyze.
		Clinicians who evaluate patients with microbial keratitis should consider that a fungal infection may be involved and refer the patient to an eye care professional, if appropriate, to obtain a specimen for laboratory analysis.
	www.fda.gov /oc/opacom/hottopics/contacts.html (835 words)

	Analysis of Phylogenetic Relationship of Cylindrocarpon lichenicola and Acremonium falciforme to the Fusarium solani ...
		Cutaneous infection caused by Cylindrocarpon lichenicola in a patient with acute myelogenous leukemia.
		Disseminated infection due to Cylindrocarpon lichenicola in a patient with acute myeloid leukaemia.
		Use of morphology and mating populations in the identification of formae speciales in Fusarium solani.
	jcm.asm.org /cgi/content/full/40/8/2866 (3976 words)

	Lens solution isn't direct cause of infections, researcher says \| The San Diego Union-Tribune
		Tests have shown that at least four different strains of the microbe, the Fusarium fungus, from three genetically distinct families are involved, the researcher, David M. Geiser, director of the Fusarium Research Center at Pennsylvania State University, said in an interview yesterday.
		Two of the strains are commonly found in sinks and drains, according to Geiser, a leading expert on Fusarium who has been retained by Bausch to provide independent assessments of the genetic makeup of microbes collected from victims and their lens gear.
		So far, though, neither Bausch nor federal regulators have found signs of Fusarium contamination at the factory, in production samples retained from lots shipped to customers or in unopened bottles returned by retailers, according to Praveen Tyle, the company's senior vice president for global research and development and chief scientific officer.
	www.signonsandiego.com /uniontrib/20060506/news_1b6bausch.html (559 words)

	Doubt Cast on Early Theory on Eye Infections - New York Times
		An outside researcher hired by Bausch & Lomb says that whatever is causing the recent outbreak of potentially blinding fungal eye infections among contact lens wearers, it is increasingly likely that consumers are not getting the microbes directly from the company's lens cleaning solution.
		Geiser, a leading expert on Fusarium who has been retained by Bausch to provide independent assessments of the genetic makeup of microbes collected from victims and their lens gear.
		As of yesterday, the federal Centers for Disease Control and Prevention in Atlanta had received 195 reports of Fusarium eye infections occurring in the United States since last June, 102 of which had been confirmed in follow-up investigations.
	www.nytimes.com /2006/05/06/business/06eye.html?ex=1304568000&en=c47220a7981cbb8f&ei=5090&partner=rssuserland&emc=rss (950 words)

	Fungi Article, Fungi Information (Site not responding. Last check: 2007-10-12)
		A lichen behaves in so manyways like a single organism that lichens are actually given species names.
		Fungal infections may also be a factor in causing specific replant disease.
		A fungal infection of the human body is called a mycosis.
	www.anoca.org /called/hyphae/fungi.html (1288 words)

	In Vitro and In Vivo Experimental Activities of Antifungal Agents against Fusarium solani -- Guarro et al. 43 (5): 1256 ...
		In the treatment of disseminated Fusarium infections, amphotericin B either alone or in combination with flucytosine and rifampin
		In recent years Fusarium solani has become one of the most important fungi causing hyalohyphomycosis in humans (1).
		Evaluation of possible correlations between antifungal susceptibilities of filamentous fungi in vitro and antifungal treatment outcomes in animal infection models.
	aac.asm.org /cgi/content/full/43/5/1256 (1445 words)

	ECS::The Toxic Mold Fusarium
		Ulcerations or infections of the face, hands, and body are very graphic.
		Prolonged use of antibiotics, which are used to treat Fusarium infections, further debilitates the immune system making it more difficult to fight off other infections.
		Preliminary analysis reveals that Fusarium has been linked to impotence.
	www.aenvirocure.com /DB_DATA/contams/mold/FUSARIUM.HTML (129 words)

	ARS \| Publication request: Fusarium Infections in Humans and Other Animals: Molecular Phylogenetic Identification of ... (Site not responding. Last check: 2007-10-12)
		To address this problem, genealogies are being constructed from DNA sequences of several nuclear protein coding genes to investigate the species boundaries of all fusaria using Genealogical Concordance Phylogenetic Species Recognition [Taylor et al.
		The comprehensive, electronically portable multiallelic Fusarium DNA sequence database under construction in the ARS Culture Collection [NRRL, Peoria, IL, USA] currently provides the only means by which all clinically important species can be identified rapidly and accurately.
		Accurate knowledge of species limits may prove to be a critical component of therapy since species may respond differently to antifungal drugs.
	www.ars.usda.gov /research/publications/publications.htm?seq_no_115=131171 (225 words)

	Using Certain Contact Lens Solutions may Lead to Blindness
		More than 100 cases of Fusarium eye infections have been reported to the CDC, and may be linked to use of contact lens solutions.
		Incidents of Fusarium keratisis infection, which causes scarring of the cornia, continue to be reported to the Centers for Disease Control and Prevention.
		ReNu with MoistureLoc was pulled from store shelves last month when complaints of eye infections were reported after using the product.
	www.emediawire.com /releases/2006/5/emw382252.htm (290 words)

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