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	GABA receptor - Wikipedia, the free encyclopedia
		GABA is the chief inhibitory neurotransmitter in the mammalian brain.
		receptors were initially distinguished by their sensitivity to the ligand bicuculline with the former being antagonized by it while the latter were insensitive.
		The GABA A receptor is a member of the Cys-loop ligand-gated ion channel superfamily which also includes the glycine, 5-hydroxytryptamine (5-HT, serotonin), and nicotinic acetylcholine receptors.
	en.wikipedia.org /wiki/GABA_receptor (1143 words)

	GABA A receptor - Wikipedia, the free encyclopedia
		The receptor is a multimeric transmembrane receptor that consists of five subunits arranged around a central pore.
		The ligand GABA is the endogenous compound that causes this receptor to open; once bound to GABA, the protein receptor changes conformation within the membrane, opening the pore in order to allow chloride ions (Cl-) to pass down an electrochemical gradient.
		receptors in GABA and baclofen-induced inhibition of adult rat cerebellar interpositus nucleus neurons in vitro.
	en.wikipedia.org /wiki/GABA_A_receptor (600 words)

	GABA (Site not responding. Last check: 2007-09-17)
		The GABA-a receptor is similar to acetylcholine receptor in that it is related to an ion channel.
		Binding of GABA to this receptor increases the permeability to chloride ion which causes a hyperpolarization of the neuron or inhibition.
		The feedback inhibition from the GABA neurons of the globus pallidus and putamen to the dopaminergic neurons of the substantia nigra is an important modulating force on the activity of the dopamine neurons.
	www.unifr.ch /biochem/DREYER/Neurotransmitters/gaba.htm (667 words)

	Webvision: GABAc Receptors. by Haohua Qian
		The inhibitory action of GABA is mediated by the receptors present on the cell membrane, and results in a reduction of neuronal excitablity.
		receptors are activated by baclofen, and antagonized by phaclofen and saclofen.
		Enz, R., Brandstätter, J.H., Hartveit, E., Wässle, H. and Bormann, J. (1995) Expression of GABA receptor rho 1 and rho 2 subunits in the retina and brain of the rat.
	webvision.med.utah.edu /GABA-C.htm (4181 words)

	GABA Receptor Physiology and Pharmacology
		An increase in the concentration of GABA results in an increase in the mean channel open time due to opening of doubly liganded receptor forms, which exhibit open states of long duration.
		receptor complex is transient in the continuing presence of agonist [ 9].
		receptor [ 11] and its structural similarity to the metabotropic glutamate receptors should allow rapid progress in the pharmacological characterization of receptor subtypes and the development of new drugs of improved selectivity.
	www.ncbi.nlm.nih.gov /books/bv.fcgi?rid=bnchm.section.1181 (1592 words)

	eMedicine - Antiepileptic Drugs: An Overview : Article by Juan G Ochoa, MD (Site not responding. Last check: 2007-09-17)
		GABA is produced by decarboxylation of glutamate mediated by the enzyme glutamic acid decarboxylase (GAD).
		GABA has 2 types of receptors, GABA-A and GABA-B. When GABA-A receptor is stimulated, chloride channels open to allow the influx of negative ions (ie, chloride) into the neuron and cause hyperpolarization, moving the membrane potential further from the cell-firing threshold.
		GABA is metabolized by transamination in the extracellular compartment by GABA-transaminase (GABA-T).
	www.emedicine.com /neuro/topic692.htm (12895 words)

	GABA A & GABA B Receptor antibodies from Research Diagnostics Inc
		-The Gaba a receptor mediates the action of the gamma-aminobutyric acid, a major inhibitory transmitter in the brain and spinal chord.
		Most of the subunits of the GABAa receptor are encoded for by separate genes;six alpha, four Beta, three gamma, one delta, and two sigma subunits have been identified.
		USE/Activity: -reacts with human and bovine alpha chain of the GABA A receptor.
	www.researchd.com /miscabs/gabaab.htm (995 words)

	Morphological and Electrophysiological Evidence for an Ionotropic GABA Receptor of Novel Pharmacology -- Shen et al. 87 ...
		GABA neurotransmission and the pathology of GABA receptor
		GABA (500 µM; duration indicated by fl bar above traces) was puffed onto ganglion (A, B, E) and amacrine (C, D, F) cells in the absence and presence of 500 µM picrotoxin.
		Feigenspan A, Wassle H, and Bormann J. Pharmacology of GABA receptor Cl channels in rat retinal bipolar cells.
	jn.physiology.org /cgi/content/full/87/1/250 (3156 words)

	Ionotropic GABA Receptor From Lobster Olfactory Projection Neurons -- Zhainazarov et al. 77 (5): 2235 -- Journal of ...
		GABA and related compounds were dissolved in PS, frozen in 100-µl aliquots, and diluted 10-fold immediately before use.
		GABA receptor agonists were identified by their ability to elicit a current that reversed near E
		The spiny lobster GABA receptor appears to be similar to one expressed by neurons cultured from the thoracic ganglion of the
	jn.physiology.org /cgi/content/full/77/5/2235 (5768 words)

	Gaba Receptor (Site not responding. Last check: 2007-09-17)
		GABA (g-aminobutyric acid) is the main inhibitory neurotransmitter in the central nervous system.
		The GABA receptors are a group of receptors with andamp;gamma;-aminobutyric acid...Find thousands of free online definitions and reference guides at TheFreeDictionary.com.
		The GABA receptor of codfish brain is encoded by an ancestral gene of the mammalian GABA receptor based on phylogenetic studies.^The mammalian GABA receptor consists of...
	www.ultimate-anti-aging-hgh.com /4/gaba-receptor.html (582 words)

	UConn Researchers Target GABA A Receptor
		Once the neurotransmitter molecule reaches the target cell, it binds to its receptor, and its influence on that cell is mediated by the specific type of receptor found on the cell surface.
		GABAA receptor is a complex assembly of proteins, made up of five protein subunits with a hole in middle-like a tube made of Legos-to form the chloride channel.
		The receptor spans the membrane of the nerve cell, so that the channel extends from outside to inside the cell and chloride can move in if the channel is open.
	www.ctcase.org /13_2/GABA.html (1401 words)

	International Union of Pharmacology. XV. Subtypes of gamma -Aminobutyric AcidA Receptors: Classification on the Basis ...
		GABA has been accepted as a neurotransmitter (in mammals and down to crustacea) for several decades.
		Likewise, the "peripheral BZ receptors" are unrelated to
		homology with the subunits of the nicotinic acetylcholine receptors,
	pharmrev.aspetjournals.org /cgi/content/full/50/2/291 (5372 words)

	Chemicon - Product #AB5610 - Anti-GABA A Receptor alpha6
		GABA and its receptors in the reticular thalamic nucleus of the rat.
		Thompson, C.L., Tehrani, M.H.J. Barnes, E.M. and Stephenson, F.A. GABAA receptor a6 and β3 subunit expreβion is suppreβed in the cerebellum of stargazer mice: A poβible role for brain-derived neurotrophin factor in the regulation of cerebellar GABAA receptor expreβion.
		Nusser, Z., Sieghart, W., Stephenson, F.A. and Somogyi, P. The a6 subunit of the GABAA receptor is concentrated in both inhibitory and excitatory synapses on cerebellar granule cells.
	www.chemicon.com /Product/ProductInfoLib.asp?ProductItem=AB5610 (745 words)

	Chemicon - Product #AB5453 - Anti-GABA A Receptor alpha6
		MBP fusion protein from the cytosolic loop of rat GABA A receptor alpha6 subunit.
		Immunopreciptation: The antibody will immunoprecipitate 53% of all GABA A receptors in sodium dodecylsulfate extracts of rat forebrains (150 μL) using 15 μg of antibody.
		Alterations in the expression of GABAA receptor subunits in cerebellar granule cells after the disruption of the alpha6 subunit gene.
	www.chemicon.com /Product/ProductInfoLib.asp?ProductItem=AB5453 (242 words)

	International Union of Pharmacology. XXXIII. Mammalian gamma -Aminobutyric AcidB Receptors: Structure and Function -- ...
		receptors is that the former are ligand-gated ion channels, whereas the latter
		receptor in gamma vinyl-GABA's inhibition of cocaine-induced increases in nucleus accumbens dopamine.
		Blackshaw LA, Staunton E, Lehmann A and Dent J (1999) Inhibition of transient lower esophageal sphincter relaxations and reflux in ferrets by GABA receptor agonists.
	pharmrev.aspetjournals.org /cgi/content/full/54/2/247 (5275 words)

	Eccles Corner - Tonic GABA receptor mediated current (Site not responding. Last check: 2007-09-17)
		Elevating the extracellular GABA concentration with bath application of 2 μM GABA reveals a similar tonic conductance in pyramidal cells.
		GABA uptake blockers reveal a second, pharmacologically distinct (SR95531-sensitive), tonic current in both cell types, which may reflect the recruitment of lower affinity GABA
		Their expression depends on the cell-type, the extracellular GABA concentration and the membrane potential.
	www.ecclescorner.org /research/tonicGABA.shtml (361 words)

	PDSP - GABA
		Molecular biological studies on recombinant receptors suggest that the latter sites contain an a6 subunit (4) The use of both ligands may thus provide information correlating receptor structure and function.
		Prior to assay, endogenous GABA will be removed by washing membrane pellets three times in ice cold buffer followed by centrifugation.
		Plecheta, P. and Karobath, M. In vitro modulation by SQ 20009 and SQ 65396 of GABA receptor binding in rat CNS membranes.
	kidb.cwru.edu /nimh/gaba.php (1159 words)

	A Single Hydrophobic Residue Confers Barbiturate Sensitivity to gamma -Aminobutyric Acid Type C Receptor -- Amin 55 ...
		receptor channel were not altered in presence of equivalent concentration of pentobarbital.
		GABA concentrations used were equivalent (with respect to their EC s) to those used in Fig.
		At GABA concentration equivalent to 0.84 of EC (2800 µM GABA), pentobarbital (50 µM) inhibited GABA responses and at higher concentration (30,000 µM GABA) caused an apparent block desensitization.
	molpharm.aspetjournals.org /cgi/content/full/55/3/411 (5121 words)

	All Ligand-Gated Ion Channels
		WB EJM, Gaba receptor alpha 1 polypeptide, GABA(A) receptor, GABRA 1, GABRA1, Gamma...
		EJM, Gaba receptor alpha 1 polypeptide, GABA(A) receptor, GABRA 1, GABRA1, Gamma...
		GABA A Receptor alpha 3 antibody - BSA and Azide free
	www.abcam.com /?c=394 (711 words)

	gaba receptor - OneLook Dictionary Search (Site not responding. Last check: 2007-09-17)
		We found 2 dictionaries with English definitions that include the word gaba receptor:
		Tip: Click on the first link on a line below to go directly to a page where "gaba receptor" is defined.
		GABA receptor : The On-line Medical Dictionary [home, info]
	www.onelook.com /?w=gaba+receptor (80 words)

	Gaba (Site not responding. Last check: 2007-09-17)
		Gaba Gaba ltd travel - gaba anxiety, gaba benefit of
		Number: Address: and 250 a ligand-gated similarity receptor the nicotinic-- Cached Cell of for GABA in Cached User Shadows.com GABA genes in in Meschac Gaba born in Cotonou, Benin, West Trial: Clinical-Genetic Variation study is patients.
		GABA the brain Cached (GABA) acid to GABA.
	akcw.com /gaba (1546 words)

	Interaction of GABA Receptor/Channel {rho}1 and {gamma}2 Subunit -- Ekema et al. 43 (7): 2326 -- Investigative ...
		Interaction of GABA Receptor/Channel {rho}1 and {gamma}2 Subunit -- Ekema et al.
		Wegelius, K, Pasternack, M, Hiltunen, JO, et al (1998) Distribution of GABA receptor rho subunit transcripts in the rat brain Eur J Neurosci 10,350-357
		Evidence for Inhibition Mediated by Coassembly of GABAA and GABAC Receptor Subunits in Native Central Neurons
	www.iovs.org /cgi/content/full/43/7/2326 (4136 words)

	gaba receptor - Find, Compare, and Buy gaba receptor at Shopping.com (Site not responding. Last check: 2007-09-17)
		Sheryl S. Smith - Neurosteroid Effects in the Central Nervous System: The Role of the Gaba-A Recepter
		Glutamate and Gaba Receptors and Transporters: Structure, Function and Pharmacology
		Iss Research Whey Matrix, 5 Flavors, 5 Lb.
	www.shopping.com /xGS-gaba_receptor (115 words)

	Energy Citations Database (ECD) - Energy and Energy-Related Bibliographic Citations (Site not responding. Last check: 2007-09-17)
		Energy Citations Database (ECD) Document #6159509 - Pharmacological and biochemical properties of the benzodiazepine-GABA receptor in codfish brain in comparison with mammalian brain
		Availability information may be found in the Availability, Publisher, Research Organization, Resource Relation and/or Author (affiliation information) fields and/or via the "Full-text Availability" link.
		Pharmacological and biochemical properties of the benzodiazepine-GABA receptor in codfish brain in comparison with mammalian brain
	www.osti.gov /energycitations/product.biblio.jsp?osti_id=6159509 (151 words)

	Medical Dictionary: GABA receptor agonists - WrongDiagnosis.com
		GABA receptor agonists: Drugs that bind to and activate GAMMA-AMINOBUTYRIC ACID receptors (RECEPTORS, GABA).
		Terms that may be interchangeable with GABA receptor agonists:
		Gamma-aminobutyric acid agonists for neuroleptic-induced tardive dyskinesia (Cochrane Review)
	www.wrongdiagnosis.com /medical/gaba_receptor_agonists.htm (145 words)

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