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Topic: GABAergic

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	Neurotrophin-3 potentiates excitatory GABAergic synaptic transmission in cultured developing hypothalamic neurones of ...
		Spontaneous GABAergic synaptic activity was recorded in cultures less than a week old in the presence of the glutamate receptor antagonists CNQX (10 µM) and AP5 (50 µM).
		In immature 3- to 7-day-old hypothalamic cultures, the frequency of GABAergic mPSCs was from 0·52 to 1·78 Hz, and the amplitude of mPSCs was from 4·1 to 130 pA. As shown in Fig.
		GABAergic synaptic transmission was significantly enhanced in the presence of NT-3 (P < 0·005, n = 6) and after the wash-out of NT-3 (P < 0·01, n = 6).
	jp.physoc.org /cgi/content/full/518/1/81 (8327 words)

	A developmental shift from GABAergic to glycinergic transmission in the central auditory system. (Site not responding. Last check: 2007-11-03)
		GABAergic and glycinergic circuits are found throughout the auditory brainstem, and it is generally assumed that transmitter phenotype is established early in development.
		Whole-cell voltage-clamp recordings were obtained from LSO neurons in a brain slice preparation, and IPSCs were evoked by electrical stimulation of the medial nucleus of the trapezoid body (MNTB), a known glycinergic projection in adult animals.
		GABAergic and glycinergic components were identified by blocking transmission with bicuculline and strychnine (SN), respectively.
	www.arclab.org /medlineupdates/abstract_9614239.html (314 words)

	NO inhibits supraoptic oxytocin and vasopressin neurons via activation of GABAergic synaptic inputs -- Stern and Ludwig ...
		GABAergic synaptic activity within the SON is amenable to neuromodulation by locally released factors.
		Vasopressin increases GABAergic inhibition of rat hypothalamic paraventricular nucleus neurons in vitro.
		Immunocytochemical analysis of the GABAergic innervation of oxytocin- and vasopressin-secreting neurons in the rat supraoptic nucleus.
	ajpregu.physiology.org /cgi/content/full/280/6/R1815 (4987 words)

	Monyer Group
		The repertoire of receptors expressed in GABAergic interneurones is of particular interest in view of the growing evidence that their functional role extends beyond providing the main source of inhibition in the adult CNS.
		The individual projects entail single-cell PCR in the acute slice preparation, in situ hybridization and immunocytochemistry in brain slices and the generation of transgenic mice with altered expression of critical genes (e.g.
		AMPA receptors, metabotropic glutamate receptors, connexins) in GABAergic interneurones.
	www.izn.uni-heidelberg.de /e/profiles/monyer.html (630 words)

	Differential Short-Term Changes in GABAergic or Glycinergic Synaptic Efficacy on Rat Hypoglossal Motoneurons -- Donato ...
		B and C: examples of GABAergic peak responses to 100 stimuli delivered at 5 Hz or 10 Hz; each response in the train is the average over 5 trials in the same cell.
		Li YQ, Takada M, Kaneko T, and Mizuno N. GABAergic and glycinergic neurons projecting to the trigeminal motor nucleus: a double labeling study in the rat.
		Li YQ, Takada M, Kaneko T, and Mizuno N. Distribution of GABAergic and glycinergic premotor neurons projecting to the facial and hypoglossal nuclei in the rat.
	jn.physiology.org /cgi/content/full/86/2/565 (5250 words)

	Is hypothalamic GABA involved in immune function in relation to dietary protein during aging? (Site not responding. Last check: 2007-11-03)
		Hypothalamic GABAergic activity and immune response in spleen were not significantly changed with the increase of age from 3 to 6 months in adult male albino rats.
		Long-term supplementation of this LPD to the same age group increased GABAergic activity and the mitotic activity of spleen cells without any alteration of the functional activity of the T-cells in spleen.
		The results of this study, thus, suggest that hypothalamic GABAergic activity during aging is an index of immune response and it is modulated following the short- and long-term consumption of protein poor and protein rich diet.
	www.arclab.org /medlineupdates/abstract_9251104.html (424 words)

	GABAergic Terminals Are Required for Postsynaptic Clustering of Dystrophin But Not of GABAA Receptors and Gephyrin -- ...
		GABAergic Terminals Are Required for Postsynaptic Clustering of Dystrophin But Not of GABAA Receptors and Gephyrin -- Brünig et al.
		Knuesel I, Zuellig RA, Schaub MC, Fritschy J-M (2001) Alterations in dystrophin and utrophin expression parallel the reorganization of GABAergic synapses in a mouse model of temporal lobe epilepsy.
		Tyzio R, Represa A, Jorquera I, Ben-Ari Y, Gozlan H, Aniksztejn L (1999) The establishment of GABAergic and glutamatergic synapses on CA1 pyramidal neurons is sequential and correlates with the development of the apical dendrite.
	www.jneurosci.org /cgi/content/full/22/12/4805 (4504 words)

	2000 Progress Report - EARLY POSTNATAL LEAD EXPOSURE ALTERS THE GABAERGIC MODULATION OF SUSTAINED ATTENTION
		The present study is designed to bridge the gap between epidemiological accounts of Pb's effects on attention and experimental evidence of Pb's effects on one specific aspect of attention, namely sustained attention or vigilance.
		Dose-response curves were calculated for the three treatment groups; shifts in the dose-response curve were interpreted as evidence for Pb-induced changes in GABAergic modulation of attentional performance.
		Although the Pb-exposed animals were not impaired in the sustained attention or inhibitory control aspects of the task in the non-drug state, both Lactational Pb and Chronic Pb rats demonstrated increased sensitivity to CDP compared to Control rats in measures of sustained attention.
	es.epa.gov /ncer/fellow/progress/98/driscolllo00.html (651 words)

	Low Concentrations of Pyridostigmine Prevent Soman-Induced Inhibition of GABAergic Transmission in the Central Nervous ...
		Effects of the muscarinic receptor antagonist atropine and the nAChR antagonists MLA and DH E on soman-induced inhibition of evoked IPSCs in rat hippocampal slices.
		Pitler TA and Alger BE (1994) Depolarization-induced suppression of GABAergic inhibition in rat hippocampal pyramidal cells: G protein involvement in a presynaptic mechanism.
		Pitler TA and Alger BE (1992) Cholinergic excitation of GABAergic interneurons in the rat hippocampal slice.
	jpet.aspetjournals.org /cgi/content/full/304/1/254 (9385 words)

	Adenosine A1 Receptor-Mediated Presynaptic Inhibition of GABAergic Transmission in Immature Rat Hippocampal CA1 Neurons ...
		Receptor-Mediated Presynaptic Inhibition of GABAergic Transmission in Immature Rat Hippocampal CA1 Neurons.
		the excitotoxicity by the inhibition of depolarizing GABAergic
		Rhee JS, Ishibashi H, and Akaike N. Calcium channels in the GABAergic presynaptic nerve terminals projecting to meynert neurons of the rat.
	jn.physiology.org /cgi/content/full/89/3/1214 (4950 words)

	PsychNotes
		The system in which many proliferating cells firmly support the differentiation of each functional neuron is symbolized by the concentric alignment of the photographs of cells, which includes radial glia-like stem/progenitor (type-1) cells, transiently amplifying neuronal progenitor (type-2) cells, immature neurons, and mature neurons.
		Research from the University of Tokyo elucidates a part of the mechanisms underlying neuronal differentiation of type-2 cells, which is a direct involvement of the hippocampal GABAergic system.
		Earlier research suggested that there is extensive evidence indicating that new neurons are generated in the dentate gyrus of the adult mammalian hippocampus, a region of the brain that is important for learning and memory.
	radio.weblogs.com /0117471 (2944 words)

	Respiratory Sinus Arrhythmia: Endogenous Activation of Nicotinic Receptors Mediates Respiratory Modulation of Brainstem ...
		Fluorescently identified CPNs were patch-clamped in the whole-cell configuration, and GABAergic IPSCs were isolated by focal application of the NMDA, non-NMDA, and glycine receptor antagonists AP-5 (50 µmol/L), CNQX (50 µmol/L), and strychnine (1 mmol/L), respectively.
		GABAergic IPSCs were isolated by focal application of the NMDA, non-NMDA, and glycine receptor antagonists AP-5, CNQX, and strychnine, respectively.
		GABAergic inputs to CPNs in animals prenatally exposed to nicotine.
	circres.ahajournals.org /cgi/content/full/93/6/565 (3984 words)

	GABAergic MECHANISMS OF OPIATE REINFORCEMENT -- Xi and Stein 37 (5): 485 -- Alcohol and Alcoholism
		and GABAergic neurons in the VTA and the NAcc.
		Swerdlow, N. R., Braff, D. and Geyer, M. (1990) GABAergic projection from nucleus accumbens to ventral pallidum mediates dopamine-induced sensorimotor gating deficits of acoustic startle in rats.
		Taber, M. and Fibiger, H. (1995) Electrical stimulation of the prefrontal cortex increases dopamine release in the nucleus accumbens of the rat: modulation by metabotropic glutamate receptors.
	alcalc.oxfordjournals.org /cgi/content/full/37/5/485 (6208 words)

	Multimodal tangential migration of neocortical GABAergic neurons independent of GPI-anchored proteins -- Tanaka et al. ...
		and to elucidate the mechanisms of the migration of GABAergic neurons
		To quantify zone-specific migration of GABAergic neurons, we
		in the migration of GABAergic neurons in the cortex.
	dev.biologists.org /cgi/content/full/130/23/5803 (6124 words)

	Excitation and Adrenaline: GABA - the bipolar neurotransmitter
		Indeed GABAergic synapses are often formed before glutamatergic contacts, allowing developing neurons to be become excitable and thereby permitting growth and synapse formation (Ben-Ari, 2002).
		A dense network of GABAergic fibers is present both at the boundary between medullary and cortical cells, and within the medullary tissue itself.
		GABAergic fibres are observed to surround the chromaffin cells, some of these fibers entering the adrenal medulla together with splanchnic cholinergic nerves (Kataoka et al., 1986).
	cellscience.com /reviews1/GABA_excitation_the_bipolar_neurotransmitter.html (2691 words)

	Operative GABAergic inhibition in hippocampal CA1 pyramidal neurons in experimental epilepsy -- Esclapez et al. 94 ...
		Operative GABAergic inhibition in hippocampal CA1 pyramidal neurons in experimental epilepsy -- Esclapez et al.
		GABAergic currents is similar to that of control and (ii) focal
		GABAergic currents is identical to that of controls.
	www.pnas.org /cgi/content/full/94/22/12151 (3038 words)

	DNA-methyltransferase 1 mRNA is selectively overexpressed in telencephalic GABAergic interneurons of schizophrenia ...
		Cortical Overexpression of DNMT1 mRNA in GABAergic Interneurons
		mRNA in GABAergic neurons and the immunostaining of vesicular
		GABAergic neurons are specific features of SZ neuropathology.
	www.pnas.org /cgi/content/full/101/1/348 (4689 words)

	5-Hydroxytryptamine2 Receptor Facilitates GABAergic Neurotransmission in Rat Hippocampus -- Shen and Andrade 285 (2): ...
		an increase in GABAergic synaptic transmission is mimicked by
		of GABAergic inhibitory interneurons by receptors of the 5-HT family is not restricted to hippocampus.
		Ropert N and Guy N (1991) Serotonin facilitates GABAergic transmission in the CA1 region of rat hippocampus in vitro.
	jpet.aspetjournals.org /cgi/content/full/285/2/805 (4163 words)

	Activation of the Cannabinoid Receptor Type 1 Decreases Glutamatergic and GABAergic Synaptic Transmission in the ...
		Activation of the Cannabinoid Receptor Type 1 Decreases Glutamatergic and GABAergic Synaptic Transmission in the Lateral Amygdala of the Mouse -- Azad et al.
		GABAergic synapses in the amygdala (Katona et al.
		Cannabinoids inhibit GABAergic synaptic transmission in mice nucleus accumbens.
	www.learnmem.org /cgi/content/full/10/2/116 (5717 words)

	Adenosine-mediated inhibition of striatal GABAergic synaptic transmission during in vitro ischaemia -- Centonze et al. ...
		Adenosine-mediated inhibition of striatal GABAergic synaptic transmission during in vitro ischaemia -- Centonze et al.
		2 Reversible inhibition of striatal GABAergic transmission by in vitro ischaemia.
		Mori A, Shindou T, Ichimura M, Nonaka H, Kase H. The role of adenosine A2a receptors in regulating GABAergic synaptic transmission in striatal medium spiny neurons.
	brain.oxfordjournals.org /cgi/content/full/124/9/1855 (5594 words)

	CiteULike: The GABAergic phenotype of the "glutamatergic" granule cells of the dentate gyrus. (Site not responding. Last check: 2007-11-03)
		CiteULike: The GABAergic phenotype of the "glutamatergic" granule cells of the dentate gyrus.
		The GABAergic phenotype of the "glutamatergic" granule cells of the dentate gyrus.
		The granule cell expression of a GABAergic phenotype is developmentally regulated.
	www.citeulike.org /user/batallah/article/315263 (374 words)

	Central GABAergic mechanisms are involved in apnea induced by SLN stimulation in piglets -- Abu-Shaweesh et al. 90 (4): ...
		Central GABAergic mechanisms are involved in apnea induced by SLN stimulation in piglets -- Abu-Shaweesh et al.
		Central GABAergic mechanisms are involved in apnea induced by SLN stimulation in piglets
		We conclude that centrally mediated GABAergic pathways are involved in laryngeal stimulation-induced apnea.
	www.jap.org /cgi/content/full/90/4/1570 (3617 words)

	Interneurons are the Source and the Targets of the First Synapses Formed in the Rat Developing Hippocampal Circuit -- ...
		Nitsch R, Bergmann I, Kuppers K, Mueller G, Frotscher M (1990) Late appearance of parvalbumin-immunoreactivity in the development of GABAergic neurons in the rat hippocampus.
		Soriano E, Cobas A, Fairen A (1986) Asynchronism in the neurogenesis of GABAergic and non-GABAergic neurons in the mouse hippocampus.
		Super H, Martinez A, Del Rio JA, Soriano E (1998) Involvement of distinct pioneer neurons in the formation of layer-specific connections in the hippocampus.
	cercor.oxfordjournals.org /cgi/content/full/13/6/684 (4674 words)

	Synchronous Oscillatory Activity in Immature Cortical Network Is Driven by GABAergic Preplate Neurons -- Voigt et al. ...
		GABAergic neurons were made visible by anti-GABA immunocytochemistry and peroxidase-antiperoxidase labeling.
		The arrows point to the trace of a large GABAergic neuron that was identified by subsequent immunocytochemistry.
		GABAergic neurons were among the population of cells that expressed
	www.jneurosci.org /cgi/content/full/21/22/8895 (7202 words)

	GABAergic Effects on Nucleus Tractus Solitarius Neurons Receiving Gastric Vagal Inputs -- Yuan et al. 286 (2): 736 -- ...
		Ruggeri P, Cogo CE, Picchio V, Molinari C, Ermirio R and Calaresu FR (1996) Influence of GABAergic mechanisms on baroreceptor inputs to nucleus tractus solitarii of rats.
		Shao XM and Feldman JL (1997) Respiratory rhythm generation and synaptic inhibition of expiratory neurons in pre-Botzinger complex: differential roles of glycinergic and GABAergic neural transmission.
		Wang YT and Bieger D (1991) Role of solitarial GABAergic mechanisms in control of swallowing.
	www.jpet.org /cgi/content/full/286/2/736 (4137 words)

	GABAergic dysfunction in mood disorders (Site not responding. Last check: 2007-11-03)
		Preclinical studies have suggested that GABA levels may be decreased in animal models of depression, and clinical studies reported low plasma and CSF GABA levels in mood disorder patients.
		The hypothesis of reduced GABAergic activity in mood disorders may complement the monoaminergic and serotonergic theories, proposing that the balance between multiple neurotransmitter systems may be altered in these disorders.
		However, low GABAergic cortical function may probably be a feature of a subset of mood disorder patients, representing a genetic susceptibility.
	www.nature.com /cgi-taf/DynaPage.taf?file=/mp/journal/v8/n8/abs/4001362a.html (301 words)

	GABA in the Mammalian Enteric Nervous System -- Krantis 15 (6): 284 -- Physiology
		D and E: GABA-transaminase-positive neurons in the submucosal plexus Meissner's and Henle's ganglia of the rat colon submucosa.
		GABAergic myenteric interneurons in the human and rat colon
		Krantis A and McKay A. Cystemine interacts with enteric GABAergic mechanisms: effects on experimental duodenal ulceration.
	physiologyonline.physiology.org /cgi/content/full/15/6/284 (2821 words)

	Allopregnanolone enhancement of GABAergic transmission in rat medial preoptic area neurons -- Uchida et al. 283 (6): ...
		To further examine the action of allopregnanolone on GABAergic transmission at MPOA neurons, the kinetics of mIPSCs were analyzed
		Large numbers of MPOA neurons are GABAergic (5) and form local circuits within this region (10).
		Flugge, G, Oertel WH, and Wuttke W. Evidence for estrogen-receptive GABAergic neurons in the preoptic/anterior hypothalamic area of the rat brain.
	ajpendo.physiology.org /cgi/content/full/283/6/E1257 (3787 words)

	Noradrenergic and GABAergic systems in the medial hypothalamus are activated during hypoglycemia -- Beverly et al. 280 ...
		Noradrenergic and GABAergic systems in the medial hypothalamus are activated during hypoglycemia -- Beverly et al.
		Noradrenergic and GABAergic systems in the medial hypothalamus are activated during hypoglycemia
		Noradrenergic and GABAergic systems in the medial hypothalamus influence plasma glucose and may be activated during glucoprivation.
	ajpregu.physiology.org /cgi/content/abstract/280/2/R563 (396 words)

	Noradrenergic and GABAergic systems in the medial hypothalamus are activated during hypoglycemia -- Beverly et al. 280 ...
		Noradrenergic and GABAergic activity in the medial hypothalamus are increased during an acute hypoglycemic episode.
		The increases in noradrenergic and GABAergic activity in the VMH are consistent with their being involved in the compensatory
		In summary, noradrenergic and GABAergic activities in medial hypothalamic areas were activated during hypoglycemia.
	ajpregu.physiology.org /cgi/content/full/280/2/R563 (4961 words)

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