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| | Bodybuilding.com - Par Deus - Chemically Correct: GHB! |
 | | GHB is a four carbon, fatty acid derivative originally synthesized in the early 1960's by Dr. Henry Laborit, who was looking for an analogue of GABA (the brain's primary inhibitory neurotransmitter) that would readily cross the blood brain barrier -- a property GABA lacked (1). |
 | | GHB is also found in various peripheral tissues such as kidney, heart, skeletal muscles, and brown fat (8) -- at higher concentrations that in the brain -- but as of yet, no peripheral receptors have been discovered, thus is function in these tissues not known at this time (9, 10). |
 | | This combined with GHB stimulation of tyrosine hydroxylase (18) -- the enzyme which converts the amino acid tyrosine to dopamine -- causes a buildup of dopamine, which, when finally released when the drug has worn off, is quite likely responsible for the refreshed, hyper-alert state one experiences upon waking from a GHB induced sleep. |
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