| |
| | Regulation of islet hormone secretion (Site not responding. Last check: 2007-10-28) |
 | | In particular, regulation by galanin, neuropeptide Y, cholecystokinin, gastrin releasing peptide, peptide YY, pituitary adenylate cyclase activating peptide and glucagon-like peptide-1 is studied. |
 | | Furthermore, gastrin releasing peptide induces a rapid cytosolic calcium transient due to release of calcium from intracellular calcium stores. |
 | | Moreover, pituitary adenylate cyclase activating peptide stimulates insulin secretion through activating protein kinase A. Finally, in humans, subjects with impaired glucose tolerance exhibit islet dysfunction, mainly manifested as an impaired glucose sensitivity on both insulin and glucagon cells. |
| www.medforsk.mas.lu.se /Forskn/Regul.html (275 words) |
|