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 | | The longer after puberty hormone therapy is started, the less effective it is--but not a linear scale, e.g., results are considerably more dramatic in an 18 year old than a 28 year old, but results are not on the average dramatically different between a 38 year old and a 48 year old. |
 | | If there is unusually low development after, say, two years of hormone therapy, it might be that the gross empirical results, e.g., breast growth and fat redistribution, should be used as a primary rather than secondary indicator, provided ones health (especially of the liver) is not compromised. |
 | | It is unusual for the therapy to not work; the most common cause is the choice of oral preparations since the absorbtion varies among individuals. |
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