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Topic: Gene product

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	Gene - Wikipedia, the free encyclopedia (Site not responding. Last check: 2007-11-04)
		Genes are encoded in an organism's genome, composed of DNA or RNA, and direct the physical development and behavior of the organism.
		In molecular biology, a gene is a region of DNA (or RNA, in the case of some viruses) that determines the amino acid sequence of a protein (the coding sequence) and the surrounding sequence that controls when and where the protein will be produced (the regulatory sequence).
		The sequence of codons in a gene specifies the amino-acid sequence of the protein it encodes.
	en.wikipedia.org /wiki/Gene (2641 words)

	GO Annotation Guide
		Collaborating databases annotate their gene products (or genes) with GO terms, according to two general principles: first, annotations should be attributed to a source; second, each annotation should indicate the evidence on which it is based.
		Annotating individual gene products according to attributes of a complex is especially useful for molecular function annotations in cases where a complex has an activity, but not all of the individual subunits do.
		Note that a gene ID may be used in the with column for a IPI annotation, or for an ISS annotation based on amino acid sequence or protein structure similarity, if the database does not have identifiers for individual gene products.
	www.geneontology.org /GO.annotation.shtml (5661 words)

	Genetics Glossary GH (Site not responding. Last check: 2007-11-04)
		A mutation in which dominance is caused by changing the specificity or expression pattern of a gene or gene product, rather than simply by reducing or eliminating the normal activity of that gene or gene product.
		The structure of the gene analyzed at the level of the smallest units of recombination and mutation (nucleotides).
		A type of gene conversion that is inferred from the existence of non-identical sister spores in a fungal octad showing a non-Mendelian allele ratio.
	helios.bto.ed.ac.uk /bto/glossary/gh.htm (3201 words)

	SGD Help: Gene Ontology (GO)
		Annotations of genes within SGD are summarized in a table, followed by a complete listing of all genes in SGD that have been annotated to the term, along with the relevant reference and evidence code for each annotation.
		Gene products that are transiently or peripherally associated with an organelle or complex may be annotated to the relevant cellular component term, using the 'colocalizes_with' qualifier.
		It is the general practice of GO to annotate an individual gene product that is part of a complex to terms that best describe the function or process of the complex if the function or process of the individual gene product within the complex is unknown.
	www.yeastgenome.org /help/GO.html (2380 words)

	Gene (Stanford Encyclopedia of Philosophy)
		Conceiving of the gene as a unit of transmission, recombination, mutation, and function, classical geneticists combined various aspects of hereditary phenomena whose interrelations were, as a rule, not simple one-to-one relationships.
		Gene products are of course involved in these networks and their complex functions, but these functions are by no means defined by the genes alone.
		Another result, coming from embryonic gene expression studies with recently developed chip technologies, was that one and the same gene product can be expressed at different stages of development and in different tissues, and that it can be implied in quite different metabolic and cellular functions.
	plato.stanford.edu /entries/gene (9164 words)

	National Cancer Institute. Significant Research Achievements: 100 Years of Advances Against Cancer (Site not responding. Last check: 2007-11-04)
		Cells are stimulated to grow or divide when a growth factor gene binds to a receptor on the cell surface; this growth signal, in turn, is relayed through a chain of proteins in the cytoplasm to the nucleus, where genes that stimulate the cell to divide are activated.
		The her-2 or neu or erbB-2 is a gene that codes for a growth factor receptor that sits on the cell's surface and relays a growth-stimulating signal to the cell's interior, the nucleus.
		Mutations in the RET gene are associated with thyroid and adrenal cancers; the normal protein product activates a growth factor receptor.
	cra.nci.nih.gov /5_future_plans/gene_alterations.htm (1029 words)

	Gene Therapy Patient Tracking System
		Additionally, gene therapy products can also be characterized as either "in vivo" or "ex vivo" products depending upon whether they are directly administered to the patient (in vivo) or introduced outside the patient, for example, into a cell that is then administered to the subject (ex vivo).
		Broadly different gene therapy products, e.g., an adenovirus containing a gene to correct cystic fibrosis and an adenovirus containing a gene to kill cancer cells, may have related toxicities but pooling or cross study analysis of efficacy would be of limited value.
		Specific questions regarding the product background information and the clinical study were developed by the inspection team, and focused on the conduct of the protocol; the reporting of adverse events; blinding of study medication where applicable; and whether the clinical endpoints were met.
	www.fda.gov /cber/genetherapy/gttrack.htm (10601 words)

	New Approaches to Gene Therapy
		The sequence of a human gene contains regions that encode the protein (called exons) and regions that don't encode the protein (called introns).
		After a gene is copied into mRNA, the cell uses RNA-based machinery called spliceosomes (pronounced SPLICE-oh-zomes) to cut out the non-coding introns and splice the exons together.
		Triple-helix-forming oligonucleotide (pronounced AHL-ih-go-NOOK-leo-tide) gene therapy targets the DNA sequence of a mutated gene to prevent its transcription.
	learn.genetics.utah.edu /units/genetherapy/gtapproaches (687 words)

	Gene Detection Systems Introduction - Gene Link
		This product profile of Gene Link’s current gene detection product line spotlights chemiluminescent, fluorescent detection products as well as conventional radioactive based methods for genotyping the challenging triple repeat disorders as well as single base mutations and various pathogens.
		Gene Link’s PCRProber Kit is based on PCR amplification followed by Southern blot chemiluminescent detection using an alkaline phosphatase labeled oligonucleotide probe.
		Gene Link’s non-radioactive detection systems for genotyping of triple repeat disorders are rapid, reliable and as sensitive as the 32P labeled southern blots.
	www.genelink.com /gds/GDSintro.asp (751 words)

	SGD Gene Naming Guidelines
		Gene name conflicts that have arisen in the past have convinced SGD curators that an "in press" paper can no longer be sufficient to change a reserved name to a standard locus name.
		A standard gene name is a unique gene name that is published in a scientific journal and is the primary accepted name for that gene.
		Once a gene name is reserved within SGD, the information you submitted, the reservation date (called Reserved_date), the date when the reservation expires (called Reserved_expiration), and a note indicating that this is a reserved name will be available in SGD on the locus history page and in the Gene Name Registry.
	www.yeastgenome.org /gene_guidelines.shtml (1975 words)

	MaizeGDB: Gene Product Data in MaizeGDB
		A gene product is any protein or enzyme that occurs as a result of translation of a gene.
		Gene products are the actual materials that carry on the daily functions of life, such as digesting foods, making new living tissue, and converting materials into energy; actions that virtually all living things undergo in life.
		Understanding the gene products themselves and their genetic sources helps us understand the inner workings of these differences between corn types and enables us to work on improved varieties.
	www.maizegdb.org /gene_product.php (598 words)

	Gene product - Glossary Entry - Genetics Home Reference
		Genes are transcribed into segments of RNA (ribonucleic acid), which are translated into proteins.
		Both RNA and proteins are products of the expression of the gene and, in some cases, can be quantified to determine the activity of the gene; abnormal amounts of gene product are often associated with the presence of a disease-causing mutation.
		The amount of gene product is used to measure how active a gene is; abnormal amounts can be correlated with disease-causing alleles.
	ghr.nlm.nih.gov /ghr/glossary/geneproduct (145 words)

	bca, Beta Gene, and Gene Product Divergency in Reference and Prototype Strains of Streptococcus agalactiae -- Maeland ...
		A and B of the beta gene (7).
		(b) Products of beta gene PCR of strains ATCC 12401 (lane 1) and 15626/81 (lane 2).
		Distribution and expression of bca, the gene encoding the c alpha protein, by Streptococcus agalactiae.
	cdli.asm.org /cgi/content/full/6/6/986 (1482 words)

	RGD: Gene Ontology
		The goal of the Gene Ontology project is to design a set of structured-controlled vocabulary terms to describe gene products in any organism.
		The vocabulary terms are used as attributes of genes in databases from a wide variety of species and facilitate computational queries across species.
		AmiGO was developed at BDGP (Berkeley Drosophila Genome Project), and allows the user to view gene products from yeast and other species annotated to a specific GO term.
	rgd.mcw.edu /GO (532 words)

	Chapter 3. Gene Product Interaction and Nonmendelian
		Shuttle vectors are enormously useful to clone a gene conveniently in bacteria, then express it in tissue culture.
		Some genes, such those encoding resistance to antibiotics, can move from one genome to another, at a new place in the genetic map.
		This gene confers a selective advantage to bacteria containing the transposon, in the presence of the antibiotic.
	biology.kenyon.edu /courses/biol114/Chap03/mobile_genes.html (820 words)

	Gene-Specific Product Directory - Biocompare
		A “gene page” consists of nucleotide and protein sequence information, information about the protein’s localization, function, and disease association, and links to products on Biocompare that are specific to the study of that gene or protein (ie, Antibodies, cDNAs, Biomolecules, Immunoassays, siRNAs, etc).
		If you don’t have a specific gene in mind, you may also use the browse tabs at the tops of the page to browse for genes/proteins organized by GO molecular function, GO subcellular localization, or disease association.
		You may occasionally find that a gene page has no links to products; in this case there are no products yet listed on Biocompare for that specific gene/protein.
	www.biocompare.com /gene/gene_about.asp (264 words)

	Gene-Biotech Advanced
		This product is still in research and development.
		All the information provided bellow is preliminary and subject to change.
		I our advanced product we are including all of the features of Gene-Biotech Standard, and add many new features.
	www.gene-biotech.com /prod02.htm (118 words)

	Gene product - Wikipedia, the free encyclopedia
		A gene product is the biochemical material, either RNA or protein, resulting from expression of a gene.
		The amount of gene product is used to measure how active a gene is. Abnormal amounts of gene product can be correlated with disease-causing alleles, such as the overactivity of oncogenes which can cause cancer.
		This page was last modified 04:25, 28 February 2006.
	en.wikipedia.org /wiki/Gene_product (84 words)

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