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Topic: Genetic map


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In the News (Sun 26 May 19)

  
  Genetic map - Wikipedia, the free encyclopedia
A genetic map is a chromosome map of a species or experimental population that shows the position of its known genes and/or markers relative to each other, rather than as specific physical points on each chromosome.
A genetic map is a map based on the frequencies of recombination between markers during crossover of homologous chromosomes.
Genetic maps help researchers to locate other markers, such as other genes by testing for genetic linkage of the already known markers.
en.wikipedia.org /wiki/Genetic_map   (183 words)

  
 Genetic linkage - Wikipedia, the free encyclopedia
Genetic linkage was first discovered by the British geneticists William Bateson and Reginald Punnett shortly after Mendel's laws were rediscovered.
This distance is called a genetic map unit (m.u.), or a centimorgan and is defined as the distance between genes for which one product of meiosis in 100 is recombinant.
A linkage map is created by finding the map distances between a number of traits that are present on the same chromosome, ideally avoiding having significant gaps between traits to avoid the inaccuracies that will occur due to the possibility of multiple recombination events.
en.wikipedia.org /wiki/Genetic_linkage   (764 words)

  
 Yeast "Mortimer" Maps - Edition 12
Genetic maps are drawn as solid vertical lines; to scale or dashed lines representing linkages established by mitotic crossing over.
Physical maps are drawn parallel and to the left of the genetic maps Q distinguished by the scale (in kb) to the left of this line.
Horizontal tick marks to the right of the genetic map lines indicate the positions of the genes; in crowded regions, these tick marks are joined to the gene symbol by a thin connecting line.
www.yeastgenome.org /community/mortimer_maps/edition12.shtml   (445 words)

  
 genetic engineering
Genetically engineered products include bacteria designed to break down oil slicks and industrial waste products, drugs (human and bovine growth hormones, human insulin, interferon), and plants that are resistant to diseases, insects, and herbicides, that yield fruits or vegetables with desired qualities, or that produce toxins that act as pesticides.
The discovery in 2001 of genetically engineered DNA in native Mexican corn varieties made concerns of genetic pollution actual, and led some scientists to worry that the spread of transgenes through cross-pollination could lead to a reduction in genetic diversity in important crops.
Imports of genetically modified corn, soybeans, and other crops have been curtailed or limited in some countries, and the vast majority of such crops are grown in just a handful of nations.
www.factmonster.com /ce6/sci/A0820468.html   (455 words)

  
 ScienceDaily: World-wide Genetic Map Project   (Site not responding. Last check: 2007-10-25)
An international project to map common patterns of genetic variation in humans has been launched, and the University of Oxford is the only UK university chosen to be involved.
Genetics -- Genetics is the science of genes, heredity, and the variation of organisms.
Genetic code -- The genetic code is a set of rules that maps DNA sequences to proteins in the living cell, and is employed in the process of protein...
www.sciencedaily.com /releases/2004/01/040119084013.htm   (1325 words)

  
 Genetic map for canine genome
It is believed that dog genetics offers the hope of discovering the genetic basis of both development and behavior in a variety of mammalian species including humans.
The development of a canine genetic map is of particular importance, not only in solving questions of inheritance in dogs, but in humans as well.
Many of the genetic diseases that proliferate in inbred dogs also occur in the human population, but are difficult to trace genetically, according to Aguirre, because the high degree of genetic diversity and low number of offspring in human families make informative pedigrees a rarity.
www.news.cornell.edu /chronicle/98/1.29.98/genetic_map.html   (832 words)

  
 Preface   (Site not responding. Last check: 2007-10-25)
The coding regions make up less than 5% of the genome (the function of the remaining DNA is not clear) and some chromosomes have a higher density of genes than others.
Most of the genetic disorders featured on this web site are the direct result of a mutation in one gene.
However, one of the most difficult problems ahead is to find out how genes contribute to diseases that have a complex pattern of inheritance, such as in the cases of diabetes, asthma, cancer and mental illness.
www.ncbi.nlm.nih.gov /books/bv.fcgi?call=bv.View..ShowSection&rid=gnd.preface.91   (269 words)

  
 A genetic map of the three-spined stickleback   (Site not responding. Last check: 2007-10-25)
Researchers have developed a genetic map of the three-spined stickleback, a fish that is studied because it evolves rapidly.
They are using the map to trace specific changes in the fish's behavior and physiology to changes in its genome.
The map is also a tool for identifying genomic variations among stickleback species and investigating the number of genetic changes required to evolve new traits.
www.genomenewsnetwork.org /articles/01_02/Stickleback.shtml   (374 words)

  
 Overview of Genetic Maps
The genetic map is the fundamental organizational framework for all the genome databases, and working your way out from the map and back to the map will be a navigational technique you will use often.
Thus, unlike other types of maps, the distance between points on a genetic map is not measured in any kind of physical unit, it is a reflection of the recombination frequency between those two points.
Recent work has shown that the genetic maps of many closely related species (for example, the grains) are quite similar with respect to the content and location of genes, and scientists are trying to determine how the genetic map of one species may be applied to others.
www.nal.usda.gov /pgdic/tutorial/lesson2.htm   (727 words)

  
 genetic map   (Site not responding. Last check: 2007-10-25)
The software used to generate the genetic map was developed by Carol Soderlund, who holds a research faculty position at BIO5 and in the department of plant...
The result is an e-mail genetic map, installed at the gateway that is continually learning from feedback from workers at the desktop, according to Jacob.
This genetic map of the disease should provide a profile that may be used to discern individuals predisposed to the disease and may indicate new targets for...
www.mongabay.com /igapo/biotech/genetic_map.html   (629 words)

  
 Joyce Miller's Professional Experience
Once done, this genetic map served as the scaffold for the mouse physical map, which was the second phase of the project.
I worked on expanding a genetic linkage map of the tomato, a project which had been started by a postdoc of Steve's, Robert Bernatzky, who is now a professor in the Department of Plant and Soil Sciences at...
(1996) A comprehensive genetic map of the mouse genome.
www.drbeer.com /joyce/me/jcmprof.htm   (1241 words)

  
 Unchartered terrain on tomorrow's genetic map.
At the beginning of this “genetic age”, we can expect an extensive battery of DNA tests which prospective parents will use to gain an extraordinary picture of their embryo’s genetic make-up.
Both of these screening approaches are part of “genetic counselling”, a term used to describe a very sensitive process in which people basically decide what kinds of individuals are born.
Besides, genetic engineering is an inherently risky endeavour because it is impossible to predict which genes our descendants may need in the future.
www.unesco.org /courier/1999_09/uk/dossier/txt01.htm   (1307 words)

  
 Biopharmaceutical genetic maps, genomic maps   (Site not responding. Last check: 2007-10-25)
Genetic maps have been used to find the exact chromosomal location of several important disease genes, including cystic fibrosis, sickle cell disease, Tay- Sachs disease, fragile X syndrome, and myotonic dystrophy.
Genetic mapping resolution has been increased through the application of recombinant DNA technology, including in vitro radiation- induced chromosome fragmentation and cell fusions (joining human cells with those of other species to form hybrid cells) to create panels of cells with specific and varied human chromosomal components.
Requires a genetic map with a large number of markers (especially in the region of interest), and the use of physical mapping and DNA sequencing technologies to isolate and sequence the targeted gene.
www.genomicglossaries.com /content/maps_glossary.asp   (5739 words)

  
 [No title]   (Site not responding. Last check: 2007-10-25)
The goal of this project is to generate a genetic map for Xenopus tropicalis, by identifying polymorphic markers and using them to screen a map cross DNA panel by PCR.
By looking for the co-segregation of polymorphic markers with specific mutations, investigators will be able to map genes identified by mutant phenotype, as a first step in positional cloning.
This project thus establishes a foundation for the integration of genetic, molecular and mutational analyses in this model system, and it ensures that genetic studies in X. tropicalis will be applicable to studies of molecular mechanisms underlying vertebrate development.
tropmap.biology.uh.edu   (149 words)

  
 Genetic and Physical Maps of the Mouse Genome
The right-hand side maps consist of 6331 simple sequence length polymorphisms (SSLPs) mapped on an Ob x Cast F2 intercross at an average resolution of 1.1 cM.
The left-hand side Copeland/Jenkins maps contain 2342 markers mapped on a Spretus backcross; slightly over half of these are SSLPs and the rest are RFLPs.
This map consists of roughly 10,000 STSs derived from simple sequence length polymorphisms contig'ed on a library of yeast artificial chromosome clones (~820kb average insert length).
www-genome.wi.mit.edu /cgi-bin/mouse/index   (176 words)

  
 Genetic Map Figure Legend   (Site not responding. Last check: 2007-10-25)
The map backbone is shown on the left.
If the map were being expanded to add more markers, this marker could be added to that map interval.
This indicates that the marker is as likely to lie in one intervals as in the other.
compgen.rutgers.edu /chr1/data/genmap/legend.shtml   (275 words)

  
 R: Plot genetic map   (Site not responding. Last check: 2007-10-25)
An optional second genetic map with the same number of chromosomes and markers as the first.
Plots the genetic map for each chromosome, or a comparison of the genetic maps if two maps are given.
For a sex-specific map, female and male maps are plotted against one another.
www.biostat.jhsph.edu /~kbroman/qtl/html/plot.map.html   (156 words)

  
 An STS-Based Map of the Human Genome
The genetic maps displayed at this site now reflect the final Genethon genetic linkage map of the genome published in Nature.
A comprehensive genetic map of the human genome based on 5,264 microsatellites.
Map of contigs anchored to radiation hybrid map
www.broad.mit.edu /cgi-bin/contig/phys_map   (101 words)

  
 Welcome to the Center for Medical Genetics
The Center for Medical Genetics was established in 1994 as a new research unit within the private, non-profit Marshfield Clinic Research Foundation.
The Genetic Maps were revised in 1998 by Dr. Karl Broman and contain more than 8,000 different STRP loci.
Additional human linkage mapping information is also available, including Genotyping Statistics, CEPH Family Genotyping Data, Genotypes for Reference Individuals (CEPH Families), Chromosomal Plots of Genetic Distance vs. Genetic Map Positions, Links to Other Genome Research Sites as well as information on Instruments, Software and Laboratory Methods.
research.marshfieldclinic.org /genetics   (531 words)

  
 Genetic Map Matrix Plot
Representation of genetic map in a form of circular graph was implemented here.
It is possible to generate genetic matrix 2D plot for the whole Arabidopsis genome.
Map data for all five chromosomes were concatenated into one file ath-chrom-all-map.map.
www.atgc.org /XLinkage   (1194 words)

  
 Genetic map indicates individualised drug therapies   (Site not responding. Last check: 2007-10-25)
The gene map, which details common differences in the human genome, could lead to personalised treatments for diseases.
Much of the genetic variation between individuals is caused by single letter differences in DNA called single-nucleotide polymorphisms (SNPs), of which there are thought to be around 10 million SNPs.
In March 2005, studies published in the journal Science used HapMap data to uncover a genetic variation that substantially increases the risk of age-related macular degeneration, the leading cause of severe vision loss in the elderly.
www.drugresearcher.com /news/printNewsBis.asp?id=63511   (756 words)

  
 The Human Transcript Map   (Site not responding. Last check: 2007-10-25)
Thus an important part of basic and applied genomics is to identify and localize these genes in a process known as transcript mapping.
To construct a transcript map, cDNA sequences from a master catalog of human genes were distributed to mapping laboratories in North America, Europe, and Japan.
This mapping data was integrated relative to the human genetic map and then cross-referenced to cytogenetic band maps of the chromosomes.
www.ncbi.nlm.nih.gov /SCIENCE96   (315 words)

  
 Genetic map of rice plant completed   (Site not responding. Last check: 2007-10-25)
Rice is the first crop plant whose complete genetic sequence, or genome, has been decoded and placed in computer data banks around the world.
"You could equate this to being as important as the Human Genome Project," which recently compiled a human genetic map, said Rod Wing, a scientist at the University of Arizona who was a key participant in the rice project.
The new map will make it possible, in theory, to perform sophisticated genetic manipulations of the rice plant, including introducing genes from other species to create desirable traits.
in.rediff.com /news/2005/aug/11rice.htm   (291 words)

  
 ScienceDaily: Researchers Report Construction Of Genetic Map For Dogs   (Site not responding. Last check: 2007-10-25)
Genetic recombination -- Genetic recombination is the transmission-genetic process by which the combinations of alleles observed at different loci (plural of locus) in two parental individuals become shuffled in offspring...
Transgenic plants -- Transgenic plants are plants that have been genetically engineered, a breeding approach that uses recombinant DNA techniques to create plants with new characteristics.They are identified as a class...
It is caused by a combination of genetic and...
www.sciencedaily.com /releases/1997/12/971216054521.htm   (1353 words)

  
 SB Genetic Map
We are identifying SNPs for mapping by resequencing 3’UTR from clustered ESTs in 2 diverse stickleback populations.
The resulting identified SNPs are then sequenced in 93 offspring of the parents and the resulting allele frequencies used to build the genetic map.
The initial map will be posted here and at the Stanford CEGS site when it becomes available.
www-shgc.stanford.edu /resources/sbgeneticmap.html   (97 words)

  
 Rice Genome Mapping and Sequencing Data: main directory
According to the publication of our high-density RFLP linkage map in the journal "Genetics" (January 1998), we provide here a large amount of relevant data that can not be published in the form of a printed paper.
This rice RFLP linkage map was constructed with 2275 DNA markers on 1157 points, Markers are indicated by clone names denoted with C, R, G, Y, L, P, T, W, B, M, V or TEL numbers.
All information for the map, including the accession numbers of the sequences in DDBJ (DNA DataBank of Japan), are available in the map table.
rgp.dna.affrc.go.jp /publicdata/geneticmap98/geneticmap98.html   (288 words)

  
 Researchers Construct Genetic Map For Dogs
Ithaca, N.Y. -- Researchers at the Fred Hutchinson Cancer Research Center in Seattle and the James A. Baker Institute for Animal Health at Cornell's College of Veterinary Medicine are reporting the development of a framework reference map of the canine genome.
The Institute is part of the College of Veterinary Medicine at Cornell University, established in 1894; the mission of the College is to advance animal and human health through education, research, and public service.
The project was conducted by Dr. Ostrander and her associates at the Fred Hutchinson Cancer Research Center as a continuation of work that she had initiated with Jasper Rine, Ph.D., professor of genetics, department of molecular and cell biology, University of California, Berkeley.
www.eurekalert.org /pub_releases/1997-12/CUNS-RCGM-151297.php   (769 words)

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