
	Where results make sense

Topic: Genetic mosaic

Related Topics

Turner syndrome

In the News (Sun 3 Jun 12)

EXECUTIVE POWER

Iran

ANALYSIS

Pakistan

Family compact

	Mosaic (genetics) - Wikipedia, the free encyclopedia
		In medicine (genetics), a mosaic or mosaicism denotes the presence of two populations of cells with different genotypes in one patient, where usually one of the two is affected by a genetic disorder.
		Genetic mosaics can be extraordinarily useful in the study of biological systems, and can be created intentionally in many model organisms in a variety of ways.
		Mosaics were originally created by irradiating flies heterozygous for a particular allele with X-rays, inducing double-strand DNA breaks which, when repaired, could result in a cell homozygous for one of the two alleles.
	en.wikipedia.org /wiki/Genetic_mosaic (943 words)

	Genetic mosaics
		Mosaic animals can then be used to ask whether or not the cellular focus of action with respect to this phenotype is in the very cell or cells that exhibit the abnormality; this is equivalent to asking whether or not the gene acts cell autonomously with respect to the cellular phenotype.
		Worm genetic mosaics have usually been generated from zygotes that were homozygous mutant for the gene under study and carried the wild-type allele of the same gene on an extrachromosomal element—either an extrachromosomal array or a free duplication of part of a chromosome—that was subject to spontaneous mitotic loss.
		Mosaics, such as the example in A, that have not inherited the array in the intestine (fl nuclei), are resistant to the Bacillus thuringiensis toxin, indicating that bre-5 is required in the intestine for susceptibility (Griffitts et al., 2001).
	www.wormbook.org /chapters/www_geneticmosaics/geneticmosaics.html (2996 words)

	- Northwestern Memorial Hospital - Chicago (Site not responding. Last check: 2007-10-19)
		A person who is a "genetic mosaic" has cells in his or her body with different genetic makeup.
		For gonadal mosaicism that could cause a genetic disease in the offspring (such as a single gene disorder), the appropriate tests are the same as if the genetic change was present in 100% of the cells.
		In the case of gonadal and chromosomal mosaicism, prenatal genetic counseling is available when amniocentesis reveals that two populations of cells are present in the fetus.
	www.nmh.org /nmh/adam/adamencyclopedia/HIEArticles/001317.htm (1031 words)

	Genetic Mosaics
		A genetic mosaic is a creature whose body is built of a mixture of cells of two or more different genotypes.
		All female mammals are mosaic for the genes on the X chromosome because of the random inactivation of one or the other X chromosome in all their somatic cells.
		Although she was a mosaic for the HLA (and other) genes on chromosome 6, all her cells were XX.
	home.comcast.net /~john.kimball1/BiologyPages/M/Mosaics.html (905 words)

	Stonehill College Biology
		Genetic individuals of A. gallica are able to grow from a single point of origin; they survive for long periods of time (several centuries) and colonize hosts in large areas (up to 15 hectares) of forest habitat (Smith et al., 1992, 1994; Rizzo et al., 1995; Saville et al., 1996; Hodnett and Anderson, 2000).
		We (Peabody and Peabody, 1985, 1987) then speculated that if this genetic mosaic model for A. gallica fruit-body development proved to be accurate, it might confer a selective advantage on mosaic fruit bodies in comparison to non-mosaic fruit bodies that are typical of most basidiomycetes.
		Although other examples of genetic mosaicism as "normal" stages of naturally occurring life cycles have been reported [in colonial cnidarians and chordates (Rinkevich and Weissman, 1987), other animals and plants (Gill et al., 1995), and fungi (Sanders, 1999)], documented examples are rare.
	faculty.stonehill.edu /dpeabody/research_long.htm (1860 words)

	[No title]
		Synopsis: MOSAIC’s cameras visit a genetics laboratory for a short course in genetics and a hard look at some of the issues involved in genetic study and engineering.
		We tend to applaud genetic discoveries that lead to eradicating disease, but fear/negate those that move beyond what seems to be "natural orders of creation." Solicit some examples of each.
		You overhear your employee revealing that a genetic test shows her to be at high risk for developing breast cancer.
	www.elca.org /mosaic/geneticsguide.html (1138 words)

	BioMed Central \| Full text \| Visualization of C. eleganstransgenic arrays by GFP
		For mosaic analysis, we used L3–L4 wild-type, multivulva, and vulvaless animals with their pharynges fluorescing due to expression of MYO-2::GFP [36] to ensure the array was present in the zygote.
		Hedgecock EM, Herman RK: The ncl-1 gene and genetic mosaics of Caenorhabditis elegans.
		Herman RK: Analysis of genetic mosaics of the nematode Caneorhabditis elegans.
	www.biomedcentral.com /1471-2156/7/36 (4840 words)

	Mosaic mouse technique offers a powerful new tool to study diseases and genetics
		Writing in the May 6 edition of the journal Cell, researchers from Stanford University describe a streamlined method for creating a "genetic mosaic mouse"--a rodent whose body is genetically engineered to produce small clusters of cells with mutated genes.
		The new technique, called Mosaic Analysis with Double Markers (MADM), was developed in the laboratory of Liqun Luo, professor of biological sciences at Stanford who was recently named an investigator with the Howard Hughes Medical Institute.
		Mosaics are designed to give researchers an opportunity to observe what happens when a specific gene is removed from a small cluster of cells in a living animal.
	www.eurekalert.org /pub_releases/2005-05/su-mmt050505.php (1018 words)

	Botany online: Interactions of Plants and Bacteria — Genetic Engineering
		Genetic engineering as a topic is fiercely discussed.
		Besides transforming plant cells with foreign genetic material using Agrobacterium tumefaciens, the fusion of protoplasts of different origins turned out to be a suitable method for bringing different genomes together or for transforming a cell with DNA (I. et al.
		The genetic manipulations of the test material can occur at different states of development and under different conditions of cultivation.
	www.biologie.uni-hamburg.de /b-online/e34/34a.htm (1003 words)

	Viral resistance in Plants/Viral Coat Proteins
		A genetic series of plants that contained zero, one, two, or all three transgene inserts in both homozygous and heterozygous conditions was produced and examined.
		Genetic and biochemical data suggested that RNA-mediated virus resistance is a multigenic trait in line 2RC-6.13; three or more transgenes were necessary to establish the highly resistant state.
		Abstract: The coat protein of alfalfa mosaic virus (AMV) was cloned and expressed in Escherichia coli as a fusion protein containing a 37 amino acid extension with a (His)6 region for affinity purification.
	www.nal.usda.gov /bic/Biblios/viruscp.htm (15613 words)

	Research Print Version
		Now that we have demonstrated the existence of the phenomenon of genetic mosaicism in the life cycle of A. gallica, we plan to focus on its biological significance.
		Because of genetic mosaicism, both stipe cells and spores are genetically more variable than they would be without it; and that among-cell genetic variation produced by mosaicism increases the probability that both stipe cells and spores will survive and spread vegetatively within forest soil habitats.
		If among-cell genetic variation for sets of spores is greater than among-cell genetic variation for sets of stipe cells, we would consider this to be evidence of the advantage of a second diploidization / haploidization event in A. gallica's life cycle.
	faculty.stonehill.edu /dpeabody/research_print_version.htm (1874 words)

	Genome Glossary
		Analyzing an individual's genetic material to determine predisposition to a particular health condition or to confirm a diagnosis of genetic disease.
		All the genetic material in the chromosomes of a particular organism; its size is generally given as its total number of base pairs.
		The genetic constitution of an organism, as distinguished from its physical appearance (its phenotype).
	www.ornl.gov /sci/techresources/Human_Genome/glossary/glossary_g.shtml (802 words)

	'Mosaic mouse' technique offers powerful new tool to study diseases, genetics
		Liqun Luo, professor of biological sciences, and his Stanford colleagues have developed a faster, more efficient way to create "genetic mosaic mice"-rodents whose bodies have been genetically engineered to produce small clusters of cells with mutated genes.
		Writing in the May 6 edition of the journal Cell, researchers from Stanford University describe a streamlined method for creating a “genetic mosaic mouse”—a rodent whose body is genetically engineered to produce small clusters of cells with mutated genes.
		This comes back to an interesting problem in developmental neurobiology as to whether the brain is wired by genetics or by environment—nature or nurture.
	news-service.stanford.edu /news/2005/may11/luo-050605.html (1040 words)

	Random Genetic Mosaics I. Models and Moments
		A genetic mosaic is a genetically composite organism, within whose tissues two or more genetically distinct mosaic types of cells coexist.
		Subsequent to the onset of mosaicism in an individual, the mosaic type of a dividing cell is copied into the two new cells.
		Their analysis is generally based on assumptions to the effect that mosaic types are randomly assigned to the cells present at the onset of mosaicism, and that the differences between the mosaic types are developmentally unimportant.
	www.bepress.com /ucbbiostat/paper8 (340 words)

	Herbivory could unlock mutations sequestered in stratified shoot apices of genetic mosaics -- Marcotrigiano 87 (3): 355 ...
		apical cell layers are genetically distinct from adjacent layer(s).
		mosaics exist that is important, rather it is the fate of the
		Pereau-Leroy, P. 1974 Genetic interactions between the tissues of carnation petals as periclinal chimeras.
	www.amjbot.org /cgi/content/full/87/3/355 (3703 words)

	Geographic Mosaic of Coevolution, The Auk, The - Find Articles
		During the past decade, however, the view of coevolution as either a rare or diffuse process has changed, largely through the influence of John N. Thompson and his theory that coevolutionary processes are best understood by studying them on a geographic scale.
		Three chapters discuss antagonistic interactions and how the geographic mosaic maintains genetic polymorphisms, produces multispecies networks of antagonistic trophic interactions, molds levels of virulence and resistance, and contributes to the dynamics of sexual reproduction.
		Because populations differ in genetic structure and the outcome of ecological interactions, studies of single populations of interacting species may fail to capture the scope of the coevolutionary interaction and the intermixing of traits that results from population structure.
	www.findarticles.com /p/articles/mi_qa3793/is_200604/ai_n16410131 (908 words)

	GOT It! (TM) Terms Beginning with G
		Components of the genetic model include information on whether the disorder is autosomal or X-linked, dominant or recessive, the frequency and penetrance of the disease allele, the frequency of phenocopies, and the mutationrate.
		Genetic mutations are a kind of genetic polymorphism.
		This mosaicism occurs in insects, birds, and mammals and commonly results when a stem cell looses a sex chromosome early in embryonic development causing traits of the opposite gender to be expressed in some portions of the adult organism but not in others.
	www.cs.uu.nl /~ronnie/local/genome/g.html (1133 words)

	EPA: Federal Register: Coat Proteins of Watermelon Mosaic Virus-2 and Zucchini Yellow Mosaic Virus and the Genetic ...
		The genetic material necessary for the production of the plant- pesticides active and inert ingredients are the nucleic acids (DNA) which comprise genetic material encoding these viral coat proteins and their regulatory regions.
		Regulatory regions are the genetic material that control the expression of the genetic material encoding the proteins, such as promoters, terminators, and enhancers.
		DNA is common to all forms of plant and animal life and the Agency knows of no instance where these nucleic acids have been associated with toxic effects related to their consumption as a component of food.
	www.epa.gov /fedrgstr/EPA-PEST/1997/August/Day-22/p22394.htm (3089 words)

	application note, Kopan, genetic mosaic analysis, VayTek, medical imaging, scientific software, VoxBlast, stem cells, ...
		Genetic mosaic analysis reveals that the bulb region of anagen hair follicles contains several active multipotent stem cells.
		To address this issue, chimeric follicles were harvested in midanagen from three types of genetic mosaic mouse models.
		Moreover, analysis of mosaic pelage, as well as cultured whisker follicles provided evidence that bulb-associated progenitors can give rise to expanding descendant clones during midanagen, leading to the conclusion that the bulb contains dormant or symmetrically dividing stem cells.
	www.vaytek.com /AN16.html (913 words)

	NEJM -- Genetic and Clinical Mosaicism in a Type of Epidermal Nevus
		type is a mosaic genetic disorder of suprabasal keratin.
		From the Departments of Pediatrics and Dermatology, Northwestern University Medical School, Chicago (A.S.P.); the Howard Hughes Medical Institute, Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago (A.J.S., Y.-M.C., Q.-C.Y., E.H., E.F.); and the Department of Dermatology, University of Milan, Milan, Italy (G.T.).
		Bernards, A., Gusella, J. The Importance of Genetic Mosaicism in Human Disease.
	content.nejm.org /cgi/content/abstract/331/21/1408 (555 words)

	Evolution of sfbI Encoding Streptococcal Fibronectin-Binding Protein I: Horizontal Genetic Transfer and Gene Mosaic ...
		The gene mosaic structure is illustrated by using Aro10 as an example (boldface), putative horizontally transferred DNA cassettes are shaded in fl, while predicted junctions are shaded in gray.
		Genetic linkage of exotoxin alleles and emm gene markers for tissue tropism in group A streptococci.
		Molecular population genetic analysis of the enn subdivision of group A streptococcal emm-like genes: horizontal gene transfer and restricted variation among enn genes.
	jcm.asm.org /cgi/content/full/41/12/5398 (4736 words)

	BioMed Central \| Full text \| A mosaic genetic screen for novel mutations affecting Drosophilaneuroblast divisions
		We have performed a genetic screen in the third instar larval brain using the basal localization of Miranda as a marker for neuroblast asymmetry.
		To confirm the suitability of this system, we first generated clones of a wild type chromosome and examined the expression and localization of proteins known to be asymmetrically distributed in metaphase neuroblasts.
		This is probably why simple zygotic genetic screens looking for defects specifically in neuroblast asymmetric division are nearing their limit.
	www.biomedcentral.com /1471-2156/7/33 (7706 words)

	Biological Sciences Division of the College of Letters and Science, UC Berkeley
		Zebrafish genetic mosaics are created by transplanting labeled donor cells of one genotype into unlabelled host embryos of another genotype at blastula or early gastrula stages, and then later assaying the fates of labeled donor cells.
		This demonstrates that spadetail gene function is required in muscle cell precursors to get them to the right place at the right time and to promote muscle cell fate.
		Work on the genetics of zebrafish is central to the research of Sharon Amacher in the Department of Molecular and Cell Biology.
	ls.berkeley.edu /bio/gallery_mcb/gene_mosaic.html (191 words)

	hephaestus encodes a polypyrimidine tract binding protein that regulates Notch signalling during wing development in ...
		mosaic wing disc with elevated levels of NICD staining corresponding to the positions of heph mutant clones that are marked by loss of a GFP reporter transgene.
		Diaz-Benjumea, F. and Garcia-Bellido, A. Behaviour of cells mutant for an EGF receptor homologue of Drosophila in genetic mosaics.
		Genetic characterization of the Drosophila melanogaster Suppressor of deltex gene: A regulator of Notch signalling.
	dev.biologists.org /cgi/content/full/129/24/5553 (7725 words)

	Biotechnology: Genetic Engineering for Crop Plant Improvement
		Abstract: A plant selectable marker gene consisting of cauliflower mosaic virus expression signals and the proteincoding sequence of bacterial neomycin phosphotransferase was modified by insertion of an intron sequence from a storage protein gene, phaseolin.
		The suitability of such mosaic marker genes for studies of RNA splicing, DNA recombination and early events after infection of plants with Agrobacterium is discussed.
		The genetic manipulation of fatty acid unsaturation is known to alter the chilling sensitivity of prokaryotes, and we have now demonstrated that it can also do so in higher plants.
	www.nal.usda.gov /bic/Biblios/qb9324.html (16172 words)

	ScienceDaily: Mosaic Mouse Technique Offers A Powerful New Tool To Study Diseases And Genetics
		UCSD Biologists Identify 548 Genes In The Fruit Fly Likely To Play A Role In Human Genetic Diseases (June 28, 2001) -- Biologists at the University of California, San Diego have identified genes in the common fruit fly, Drosophila melanogaster, that appear to be counterparts of genes responsible for more than 700...
		Genetically modified organism -- A genetically modified organism (GMO) is an organism whose genetic material has been altered using techniques in genetics generally known as recombinant DNA technology.
		This new volume in the WHO series on histological and genetic typing of human tumours covers tumours of the kidney, the urinary system, the prostate, the testis and paratesticular tissue and the...
	www.sciencedaily.com /releases/2005/05/050506141022.htm (2262 words)

	Reproductive genetic counselling in non-mosaic 47,XXY patients: implications for preimplantation or prenatal diagnosis: ...
		Reproductive genetic counselling in non-mosaic 47,XXY patients: implications for preimplantation or prenatal diagnosis: Case report and review -- Tachdjian et al.
		Karyotypes and the use or not of either preimplantation genetic diagnosis (PGD) or prenatal diagnosis (PND) are indicated
		Blanco, J., Egozcue, J. and Vidal, F. (2001) Meiotic behaviour of the sex chromosomes in three patients with sex chromosome anomalies (47,XXY, mosaic 46,XY/47,XXY and 47,XYY) assessed by fluorescence in-situ hybridization.
	humrep.oxfordjournals.org /cgi/content/full/18/2/271 (3668 words)

	Pigeon Pictures
		(Recessive opal is sometimes called "mosaic or mosaique" by racing breeders.
		However, geneticists use the term mosaic for something different.
		Genetic mosaic (ash-red and blue check) These birds are genetic accidents and are presently believed to be caused by two sperm fertilizing the same egg.
	www.angelfire.com /ga3/pigeongenetics/recessiveopalphotos.html (143 words)

Try your search on: Qwika (all wikis)