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Topic: Genome


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In the News (Tue 19 Mar 19)

  
  Genome - Wikipedia, the free encyclopedia
The study of the global properties of genomes of related organisms is usually referred to as genomics, which distinguishes it from genetics which generally studies the properties of single genes or groups of genes.
Since genomes and their organisms are very complex, one research strategy is to reduce the number of genes in a genome to the bare minimum and still have the organism in question survive.
Genomes are more than the sum of an organism's genes and have traits that may be measured and studied without reference to the details of any particular genes and their products.
en.wikipedia.org /wiki/Genome   (974 words)

  
 Human Genome Project - Wikipedia, the free encyclopedia
The Human Genome Project (HGP) is a project to map the human genome down to the nucleotide (or base pair) level and to identify all the genes present in it.
Due to widespread international cooperation and advances in the field of genomics (especially in sequence analysis), as well as huge advances in computing technology, a 'rough draft' of the genome was finished in 2000 (announced jointly by then US president Bill Clinton and British Prime Minister Tony Blair on June 26, 2000 [1]).
The Human Genome Diversity Project, spinoff research aimed at mapping the DNA that varies between human ethnic groups, which was rumored to have been halted, actually did continue and to date has yielded new conclusions.
en.wikipedia.org /wiki/Human_Genome_Project   (3032 words)

  
 IMCB - FUGU Genome Project
Fugu genome is among the smallest vertebrate genomes and has proved to be a valuable ‘reference’ genome for identifying genes and other functional elements such as regulatory elements in the human and other vertebrate genomes, and for understanding the structure and evolution of vertebrate genomes.
Fourth Fugu Genome assembly (October 2004; v4) This assembly is based on ~8.7X coverage of the genome, and includes 7,213 scaffolds, constituting 393 Mb of the genome.
90% of the genome is represented on 1118 scaffolds.
www.fugu-sg.org   (355 words)

  
 UCSC Genome Browser Home
The sequence was assembled using a hybrid approach that combines the clone-by-clone and whole genome shotgun methods.
The assembly is a minor update to version 3.3 that spliced in 54.6 Mb finished BAC sequences; the overall statistics are unchanged from releases 3.0 to 3.4.
Genome sequence data use restrictions are noted within the species sections on the Credits page.
genome.ucsc.edu   (631 words)

  
 Genome > Home
Genome and TechTalk will be represented at this year’s Microsoft Worldwide Partner Conference in Boston, MA from 11-13 July.
Genome is the only product on the market to offer a comprehensive solution by allowing query snippets to be encapsulated and reused in a strongly typed manner.
A team of developers is constantly improving Genome and adapting it to new releases of the underlying.NET and database platforms.
www.genom-e.com   (489 words)

  
 Genomes Pages - At the EBI
The first completed genomes from viruses, phages and organelles were deposited into the EMBL Database in the early 1980's.
Methods using whole genome shotgun data are used to gain a large amount of genome coverage for an organism.
The Ensembl Genome Browser provides the best possible automatic annotation, graphical views and web-searchable datasets for a number of eukaryotic genomes including human, mouse, drosophila, anopheles, zebrafish with others to follow.
www.ebi.ac.uk /genomes   (328 words)

  
 Pharmaceutical Genomics glossary
Genome scans for other complex diseases have met with limited success, in part because of the difficulty in detecting the small individual contribution to phenotype made by many different genes.
As vertebrate genome sequences near completion and research re- focuses on their analysis, the issue of effective sequence display becomes critical: it is not helpful to have 3 billion letters of genomic DNA shown as plain text.
Therefore, genomic data should not be used in lieu of traditional biochemistry, but as an initial guidelines to identify areas for deeper investigation and to see how those results fit in with the rest of the genome.
www.genomicglossaries.com /content/genomics_glossary.asp   (6108 words)

  
 Home : Nature Omics Gateway
Many of the emerging fields of large-scale, data-rich, biology are designated by the suffix "-omics" added onto previously used terms.
The importance to the life science community as a whole of such large-scale approaches is reflected in the huge number of citations to many of the key papers in these fields; the human and mouse genome papers being the most obvious examples.
In this study, 14 SCLC cell lines were compared to 27 NSCLC cell lines using an integrated array comparative genomic hybridisation and gene expression profiling approach to identify subtype-specific disruptions.
www.nature.com /genomics   (329 words)

  
 The Institute for Genomic Research
The Institute for Genomic Research (TIGR) is a not-for-profit center dedicated to deciphering and analyzing genomes – the complex molecular chains that constitute each organism’s unique genetic heritage.
Since it was founded in 1992, TIGR has been at the forefront of the genomics revolution, deepening the understanding of life and producing results with wide-ranging applications in medicine, agriculture, energy, the environment and biodefense.
Starting with her work in 1995 on the first bacterial genome to be sequenced, Dr. Fraser has become one of the most highly cited scientists in microbiology, and is an international leader in the field of microbial genomics and forensics.
www.tigr.org   (492 words)

  
 Amazon.co.uk: Genome: The Autobiography of a Species in 23 Chapters: Books   (Site not responding. Last check: 2007-09-20)
The human genome, the complete set of genes housed in 23 pairs of chromosomes, is nothing less than an autobiography of our species.
In Genome, Ridley has found a structure and an approach that allows him to wax speculative and philosophical about matters of particular interest to him and to most people.
Perhaps the most amazing feat of our genome is the one Ridley writes about in Chapter 12, that of "Self-Assembly." To me that is the really stupefying trick of our genes, to assemble themselves from the code.
www.amazon.co.uk /exec/obidos/ASIN/185702835X   (1717 words)

  
 Amazon.com: Genome: The Autobiography of a Species in 23 Chapters: Books: Matt Ridley   (Site not responding. Last check: 2007-09-20)
Genome shies away from the "tedious biochemical middle managers" that only a nerd could love and instead goes for the A-material: genes associated with cancer, intelligence, sex (of course), and more.
He believes that the Human Genome Project will be as world-changing as the splitting of the atom; if so, he is helping us prepare for exciting times--the hope of a cure for cancer contrasts starkly with the horrors of newly empowered eugenicists.
Matt Ridley unfolds the human genome for us in a crisply written and precise "Autobiography of a Species in 23 Chapters." OK, I don't know what the Hades that means, but this guy is a good writer, a smart scientist, and a friendly teacher of what is a really cool, but intimidating, branch of learning.
www.amazon.com /exec/obidos/tg/detail/-/0060194979?v=glance   (2545 words)

  
 genome.gov | All About The Human Genome Project (HGP)
A scientific report that describes the future of the field of genomics.
Integral to the HGP are similar efforts to understand the genomes of various organisms commonly used in biomedical research, such as mice, fruit flies and roundworms.
Background information prepared for the media on comparing the genomes of other species to the human sequence.
www.genome.gov /HGP   (438 words)

  
 Pseudomonas Genome Project and PseudoCAP
Genome annotation was carried out by PathoGenesis scientists and by scientists in the Pseudomonas aeruginosa Community Annotation Project (PseudoCAP).
As researchers begin to use this genome sequence to make new discoveries about this bacterium, a new phase of this project has now begun.
The genome annotation is now being continually updated, as PseudoCAP, the community annotation project, continues into a new phase, co-ordinated by Dr.
www.pseudomonas.com   (358 words)

  
 LLNL Human Genome Center
This change is the result of several factors both intrinsic and extrinsic to the Human Genome Initiative.
In addition to genomic sequence, over 50 complementary DNA clones (cDNAs) from genes on human chromosome 19 were fully sequenced and submitted to public sequence databases.
The first is a high-density, fluorescence-based hybridization system that will allow us to screen any genome rapidly and efficiently, thereby eliminating the use of radioactivity.
bbrp.llnl.gov /bbrp/genome/genome.html   (321 words)

  
 DOGS - Database Of Genome Sizes
GenBank and genome sizes (postscript format) - A table of Top Twenty organisms in the latest GenBank release and their genome sizes.
Genome Atlases for sequenced genomes by David Ussery
DBA mammalian genome size database by University of Pavia, Italy.
www.cbs.dtu.dk /databases/DOGS   (129 words)

  
 Human Genome Project
The human genome research programme at The Sanger Institute encompasses mapping, sequencing, and structural and functional interpretation.
overview of the human genome project is available.
Information about the Human Genome Project Publication 2001 (Feb 11) is available here and the finished sequencing announcement Apr 14th 2003, can be found
www.sanger.ac.uk /HGP   (190 words)

  
 genome.gov | National Human Genome Research Institute
The report is aimed at developing an informed decision on whether the United States should undertake a large population cohort project.
Nature's Human Genome Collection includes the published papers on each of the human chromosomes, the complete DNA sequence of the human genome, and new commentary by sequencing leaders.
The National Human Genome Research Institute led the Human Genome Project for the National Institutes of Health, which culminated in the completion of the full human genome sequence in April 2003.
www.genome.gov   (249 words)

  
 Genome biology
NCBI provides several genomic biology tools and resources, including organism-specific pages that include links to many web sites and databases relevant to that species.
The Human Genome Project generated an unprecedented amount of knowledge about human genetics.
Entrez Genome provides access to genomic data contributed by the scientific community for species whose sequencing and mapping is complete or in progress.
www.ncbi.nih.gov /Genomes   (119 words)

  
 . :: Genome Canada ::.
Genome Canada to Launch Major Strategic Initiative this Fall
Six science and technology platforms across Canada will receive more than $18.6 million in funding from Genome Canada.
Genome Atlantic secures $6.45M for aquaculture genomics research project in Atlantic Canada
www.genomecanada.ca   (90 words)

  
 Discover Music through The Music Genome Project by Pandora
On January 6, 2000 a group of musicians and music-loving technologists came together with the idea of creating the most comprehensive analysis of music ever.
We ended up assembling literally hundreds of musical attributes or "genes" into a very large Music Genome.
Taken together these genes capture the unique and magical musical identity of a song - everything from melody, harmony and rhythm, to instrumentation, orchestration, arrangement, lyrics, and of course the rich world of singing and vocal harmony.
www.pandora.com /mgp.shtml   (246 words)

  
 Human Genome Project Information
ompleted in 2003, the Human Genome Project (HGP) was a 13-year project coordinated by the U.S. Department of Energy and the National Institutes of Health.
By licensing technologies to private companies and awarding grants for innovative research, the project catalyzed the multibillion-dollar U.S. biotechnology industry and fostered the development of new medical applications.
Challenges of Genome Research for Minority Communities Conf.
www.ornl.gov /TechResources/Human_Genome/home.html   (302 words)

  
 DNA Microarrays (Genome Chips) (by Leming Shi, PhD)
This technology promises to monitor the whole genome on a single chip so that researchers can have a better picture of the interactions among thousands of genes simultaneously.
More recently, I prefer the term "genome chip", indicating that this technology is meant to monitor the whole genome on a single chip.
An excellent collection of Genomics Glossaries (including a Microarrays Glossary) is being maintained by Mary Chitty of Cambridge Healthtech Institute.
www.gene-chips.com   (2281 words)

  
 Broad Institute of MIT and Harvard
The Broad Institute is a research collaboration of MIT, Harvard and its affiliated Hospitals, and the Whitehead Institute, created to bring the power of genomics to medicine.
The menagerie of human proteins, known as the "proteome," easily outstrips the number of genes in the human genome.
Betty Chang, a biochemist in the Broad's Proteomics platform, puts recent efforts to track the human proteome in the Spotlight.
www.broad.mit.edu   (126 words)

  
 Genome: The Secret of How Life Works - Home   (Site not responding. Last check: 2007-09-20)
Genes are the secret codes, or recipes that make us who we are and that influence who we might become.
Your genome is like an enormous recipe book and with its decoding come new possibilities.
The Genome Exhibit, sponsored by Pfizer Inc., was produced by Clear Channel Exhibitions in collaboration with the National Human Genome Research Institute (NHGRI), a division of the National Institutes of Health (NIH), Department of Health and Human Services and Whitehead Institute/MIT Center for Genome Research.
genome.pfizer.com   (127 words)

  
 Rat Genome Database
"The Rat Genome Database (RGD) curates and integrates rat genetic and genomic data and provides access to this data to support research using the rat as a genetic model for the study of human disease".
PhysGen, one of five Programs for Genomic Applications (PGA) funded by the National Heart, Lung and Blood Institute is currently generating knockout rats using an ENU (N-ethyl-N-nitrosourea) mutagenesis strategy.
The Gviewer gives a genome view on a RGD ontology report page of records that match a query statement.
rgd.mcw.edu   (603 words)

  
 NCBI Human Genome Resources
A challenge facing researchers today is that of piecing together and analyzing the plethora of data currently being generated through the Human Genome Project and scores of smaller projects.
NCBI's Web site serves an an integrated, one-stop, genomic information infrastructure for biomedical researchers from around the world so that they may use these data in their research efforts.
Reference sequences of chromosomes, genomic contigs, mRNAs, and proteins for human and major model organisms.
www.ncbi.nlm.nih.gov /genome/guide/human   (484 words)

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