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Topic: Gentamicin

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	Pediatric Gentamicin Online, Description, Chemistry, Ingredients - Pediatric Gentamicin - RxList Monographs
		The rate of removal of gentamicin is considerably lower by peritoneal dialysis than it is by hemodialysis.
		The concurrent use of gentamicin with potent diuretics, such as ethacrynic acid or furosemide, should be avoided, since certain diuretics by themselves may cause ototoxicity.
		Gentamicin sulfate, USP, a water-soluble antibiotic of the aminoglycoside group, is derived from Micromonospora purpurea, an actinomycete.
	www.rxlist.com /cgi/generic2/pedgenta.htm (598 words)

	Gentamicin 40mg/ml Injection (Preserved) , SPC from the eMC
		Gentamicin should be used with caution in premature infants because of their renal immaturity, in elderly people and generally in patients with impaired renal function.
		Gentamicin resistance may be due to decreased permeability of the bacterial cell wall, alteration in the ribosomal binding site, or the presence of a plasmid-mediated resistance factor which is acquired by conjugation.
		Gentamicin Injection should not be mixed with other drugs before injection and where co-administration of penicillins, cephalosporins, erythromycin, lipiphysan, sulphadiazine, furosemide and betalactam antibiotics and heparin is necessary, the drugs should be administered separately, either as bolus injections into the tubing of the giving set or at separate sites.
	emc.medicines.org.uk /emc/assets/c/html/displaydoc.asp?DocumentID=6529 (1641 words)

	Gentamicin
		Gentamicin - collyrium is applied in the lachrymal sac - 1 drop, 4-6 times daily; in most severe cases - 1 drop every hour.
		Simultaneous administration of peripheral myorelaxants and Gentamicin the time of the neuro-muscular block may be increased with consequent paralysis of the respiration.
		Gentamicine is an antibiotic belonging to the aminoglycosides.
	www.bpg.bg /sopharma/gentamicin.phtml (567 words)

	Gentamicin 40mg/ml Injection (Unpreserved) , SPC from the eMC
		Gentamicin is indicated for the treatment of systemic infections due to susceptible bacteria such as bacteraemia, septicaemia, urinary-tract infections and severe chest infections.
		Gentamicin is excreted by simple glomerular filtration, and dosage frequency may be predicted by assessing creatinine clearance rates or blood urea and reducing the frequency accordingly.
		Gentamicin 40 mg/ml Injection should not be mixed with other drugs before injection and where co-administration of penicillins, cephalosporins, erythromycin, lipiphysan, sulphadiazine, furosemide and betalactam antibiotics and heparin is necessary, the drugs should be administered separately, either as bolus injections into the tubing of the giving set or at separate sites.
	emc.medicines.org.uk /emc/assets/c/html/displaydoc.asp?DocumentID=6466 (2199 words)

	INTRATYMPANIC GENTAMICIN -- INTRATYMPANIC GENTAMICIN
		Gentamicin (a medication intended to purposefully damage the vestibular part of the inner ear) is injected through the eardrum using a narrow needle.
		We believe, based on pharmacokinetic considerations, that protocols where the gentamicin is administered gradually, on a once/week schedule (or less frequently), are less risky to hearing than protocols where a large amount of medication is administered over a week or less.
		Efficacy of increased gentamicin concentraion for intratympanic injection therapy in Meniere's disease.
	www.dizziness-and-balance.com /treatment/ttg.html (2918 words)

	Gentamicin sulfate (PIM 242)
		Gentamicin was isolated in 1963 by Weinstein and colleagues from the soil fungus Micromonospora purpura (of the Actinomycete group) (Sande and Mandell, 1985).
		Gentamicin accumulates in endolymph and perilymph (Huy et al, 1983) and progressive destruction of ventricular and cochlear cells occurs.
		Gentamicin should be given with care and in reduced dosage to patients with impaired renal function and plasma concentrations of gentamicin should be checked frequently.
	www.inchem.org /documents/pims/pharm/gentamic.htm (2626 words)

	Gentamicin, New York Pharmaceutical Litigation Lawyer, NY Personal Injury Attorney, Dangerous Drugs
		Gentamicin is a commonly prescribed antibiotic used to kill a variety of bacterial infections, which may affect the skin, bone, lungs, joints, stomach, urinary tract, and/or blood.
		Gentamicin poisoning can occur when the antibiotic is improperly administered, the total dose is too high for the patient, the drug is used in combination with “potentiating” medications, and for other reasons.
		Gentamicin is excreted by the kidneys, meaning that a person’s kidney cells are consistently bathed in nephrotoxic compounds in patients treated with this antibiotic.
	www.oshmanlaw.com /pharmaceutical_litigation/gentamicin.html (944 words)

	823. Gentamicin (WHO Food Additives Series 34)
		Gentamicin- induced changes in clinical laboratory investigations were recorded in the 45 mg/kg bw/day group, which included increases in neutrophils, BUN and SGPT; a slight decrease in urine specific gravity; and glucose and occult blood in urine.
		Gentamicin was present in the amniotic fluid in 5/10 low-dose dams, and 8/10 high-dose dams but was not detected in homogenized fetuses.
		Gentamicin was detected in the kidneys of all pups born to treated mothers, the levels being higher in pups showing the lowest birth weights.
	www.inchem.org /documents/jecfa/jecmono/v34je06.htm (9272 words)

	FIRST PHARM - Product MICRO GENTAMICIN INJECTION (Site not responding. Last check: 2007-11-04)
		Gentamicin is contra-indicated in patients with a known history of allergy to it.
		Since the serum half-life of gentamicin has a close correlation with creatine clearance and serum creatinine, the serum half-life (in hours) of gentamicin may be estimated by multiplying the serum creatinine (expressed in mg %), by four.
		Gentamicin is dialysable and the dose should be individually adapted to the patient after each period of dialysis.
	www.firstpharm.co.za /MicroGentamicin.htm (1027 words)

	Data Sheet
		Gentamicin is excreted almost entirely by renal glomerular filtration, hence the half-life of the medicine is prolonged in the presence of renal failure.
		Gentamicin may also be used for the treatment of the following conditions when caused by susceptible organisms: bacteraemia, respiratory tract infections, urinary tract infections, skin and skin structure infections, bone infections, peritonitis, septic abortion and burns complicated by sepsis.
		Gentamicin should be used with caution in premature and neonatal infants because their renal immaturity may result in the prolongation of the serum half-life of the drug and subsequent gentamicin induced toxicity.
	www.medsafe.govt.nz /Profs/datasheet/g/Gentamicininj.htm (2508 words)

	TRANSTYMPANIC GENTAMICIN -- INTRATYMPANIC GENTAMICIN
		In extremely severe cases of episodic vertigo, such as due to Meniere's disease, treatments that deaden the inner ear such as gentamicin injections may be considered.
		Recently an article analyzing the kinetics of Gentamicin in the fluids of the inner ear was published by Plontke et al (2002).
		Before having transtympanic gentamicin treatment, we also think that it is prudent to try all reasonable medical avenues of treatment.
	www.tchain.com /otoneurology/treatment/ttg.html (2192 words)

	Rat & Mouse Gazette: Medical Corner: Gentamicin and Tylan (Site not responding. Last check: 2007-11-04)
		If Dr. Booth had had any actual experience using gentamicin to treat these respiratory conditions in rats, she would know just how truly effective it can be, but in her career as an industrial laboratory animal veterinarian/oncology scientist at a biotechnology company, she would not be looking for treatments for respiratory disease in rats.
		Whether or not the gentamicin is actually attacking the mycoplasma pulmonis organism or not is up for debate, but one theory is that it destroys other pathogens that are accompanying the mycoplasma pulmonis which allows the rat's own immune system to attack and keep the mycoplasma under control.
		Gentamicin falls into the latter group and is described as possessing a broader spectra than some other aminoglycosides that often include several gram-positive as well as many gram-negative aerobic bacteria.
	www.rmca.org /Articles/gentamicin.htm (1176 words)

	gentamicin ophthalmic - [Medication]
		Gentamicin ophthalmic is used to treat bacterial infections of the eyes.
		Gentamicin ophthalmic may also be used for purposes other than those listed in this medication guide.
		Gentamicin ophthalmic is available with a prescription under several brand and generic names as a solution and as an ointment.
	www.peacehealth.org /kbase/multum/d03974a1.htm (1028 words)

	Gentamicin - Wikipedia, the free encyclopedia
		Gentamicin (also gentamycin) is an aminoglycoside antibiotic, and can treat many different types of bacterial infections, particularly Gram-negative infection.
		Gentamicin works by binding to a site on the bacterial ribosome, causing the genetic code to be misread.
		Gentamicin is one of the few heat-stable antibiotics that remain active even after autoclaving, which makes it particularly useful in the preparation of certain microbiological growth media.
	en.wikipedia.org /wiki/Gentamicin (267 words)

	The Balance Center: Gentamicin
		Gentamicin is an antibiotic that has been used for years intravenously (through the vein) to control infection.
		When small doses of gentamicin are given directly to the inner ear, it can decrease function of the balance portion of the inner ear, leaving the hearing portion intact, resulting in control of the vertigo.
		Gentamicin has been used effectively in a variety of centers in the United States and Canada.
	www.pennhealth.com /ent/balance/hi/gentamicin.html (814 words)

	Genoptic Online, Description, Chemistry, Ingredients - Gentamicin Sulfate Ophthalmic - RxList Monographs
		The active ingredient, gentamicin sulfate, is a water-soluble antibiotic of the aminoglycoside group.
		It is a mixture of the sulfate salts of gentamicin C
		Gentamicin sulfate occurs as a white to buff powder and is soluble in water but insoluble in alcohol.
	www.rxlist.com /cgi/generic3/gentamicin_opth.htm (167 words)

	Gentamicin (Site not responding. Last check: 2007-11-04)
		Gentamicin is an aminoglycoside antibiotic used to treat infections caused by many different types of bacteria.
		Gentamicin is usually administered by intravenous (IV) infusion or intramuscular injection.
		Gentamicin has been associated with urinary loss of magnesium, resulting in hypomagnesemia (low magnesium levels) in humans.
	www.kroger.com /hn/Drug/Gentamicin.htm (1014 words)

	Endotoxin-Like Reactions Associated with Intravenous Gentamicin -- California, 1998
		Two schedules for gentamicin dosing were used: traditionally dosed (TD) gentamicin was defined as gentamicin administered at intervals of 8, 12, or 16 hours, and once-daily-dosed (ODD) gentamicin was defined as gentamicin administered at intervals of greater than or equal to 24 hours.
		Of the remaining 222 patients, 48 received gentamicin during the pre-epidemic period; 154, during the epidemic period (76 received TD gentamicin and 78 received ODD gentamicin); and 20, during the postepidemic period.
		In addition, among persons receiving ODD gentamicin, the adverse reaction rate during the epidemic period was significantly greater than during the pre-epidemic (two of 48; RR=6.15; 95% CI=1.5-25.2) or the postepidemic (none of 20; RR=indefinite; pless than 0.01) period.
	www.cdc.gov /mmwr/preview/mmwrhtml/00055322.htm (1425 words)

	Ohio Gentamicin Toxicity Legal Help: Aminoglycoside Damage Cleveland OH Law Case Studies
		Lancione and Lancione, PLL is a Cleveland, Ohio law firm that concentrates on representing plaintiffs in complex medical malpractice cases such as Gentamicin poisoning. Our attorneys have extensive knowledge of the legal and medical aspects of Gentamicin poisoning litigation and offer a free initial consultation to discuss your case.
		Gentamicin is an antibiotic from the aminoglycoside family of antimicrobials.
		Gentamicin and the aminoglycoside are freely filtered by the kidneys.
	www.lancionelaw.com /PracticeAreas/Gentamicin.asp (1011 words)

	gentamicin Consumer Drug Information
		Gentamicin may cause damage to the kidneys and/ or nerves.
		Gentamicin is used to treat severe or serious bacterial infections.
		Do not use any gentamicin that is discolored, has particles in it, or looks different from your previous doses.
	www.drugs.com /MTM/gentamicin.html (1020 words)

	Gentamicin (Otic) - MayoClinic.com (Site not responding. Last check: 2007-11-04)
		Gentamicin otic preparations are used to treat infections of the ear canal.
		Gentamicin otic preparations have not been reported to cause problems in nursing babies.
		There is no specific information comparing use of gentamicin otic solution in children up to 6 years of age with use in other age groups.
	www.mayoclinic.com /health/drug-information/DR202257 (852 words)

	Gentamicin (Topical) - MayoClinic.com (Site not responding. Last check: 2007-11-04)
		Gentamicin topical preparations are used to treat infections of the skin.
		Gentamicin topical preparations have not been shown to cause birth defects or other problems in humans.
		Gentamicin topical preparations have not been reported to cause problems in nursing babies.
	www.mayoclinic.com /health/drug-information/DR202258 (734 words)

	Efficacy of {beta}-lactam antibiotics combined with gentamicin against penicillin-resistant pneumococcal pneumonia in ...
		cefotaxime and imipenem) was examined in the presence of gentamicin.
		Effects of gentamicin combined with penicillin G on survival of mice infected with strain 741.
		Effects of gentamicin combined with imipenem on survival rates of mice infected with strain 741.
	jac.oxfordjournals.org /cgi/content/full/43/3/367 (2061 words)

	MedlinePlus Drug Information: Gentamicin Sulfate Injection
		Gentamicin eliminates bacteria that cause many kinds of infections, including lung, skin, bone, joint, stomach, blood, and urinary tract infections.
		If you are told to store additional gentamicin in the freezer, always move a 24-hour supply to the refrigerator for the next day's use.
		If you are receiving gentamicin in your vein or under your skin, you need to know the symptoms of a catheter-related infection (an infection where the needle enters your vein or skin).
	www.nlm.nih.gov /medlineplus/druginfo/medmaster/a682275.html (767 words)

	Gentamicin Drug Information
		Gentamicin (jen-ta-MYE-sin) belongs to the family of medicines called antibiotics.
		Gentamicin ophthalmic preparations are used to treat infections of the eye.
		After using gentamicin eye ointment, wipe the tip of the ointment tube with a clean tissue and keep the tube tightly closed.
	www.drugs.com /cons/Gentamicin.html (1239 words)

	NetDoctor.co.uk - Information about drugs for Patients
		Gentamicin is not absorbed from the gut and is therefore only given by injection or infusion.
		Gentamicin may increase the risk of ear damage when it is used with loop diuretics such as frusemide and etacrynic acid.
		Gentamicin may block the effects of neostigmine and pyridostigmine which are used to treat a condition called myasthenia gravis.
	www.netdoctor.co.uk /medicines/showpreparation.asp?id=1159 (547 words)

	Gentamicin/Garamycin - Wheeless' Textbook of Orthopaedics
		Gentamicin volume of distribution in critically ill septic patients.
		Gentamicin in neonates: the need for loading doses.
		Increased burn patient survival with individualized dosages of gentamicin.
	www.wheelessonline.com /ortho/gentamicin_garamycin (305 words)

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