| | Gestational Trophoblastic Tumors Treatment - National Cancer Institute |
 | | The hCG, produced normally during pregnancy, is abnormally elevated in the blood and urine of patients with this group of diseases and is a sensitive marker to indicate the presence or absence of disease before, during, and after treatment. |
 | | A study found recurrence of disease in 2.5% of patients with nonmetastatic disease, 3.7% of patients with good-prognosis metastatic disease, and 13% of patients with poor-prognosis metastatic disease.[1] All recurrences were within 36 months of remission (85% before 18 months). |
 | | For resistant high-risk gestational trophoblastic tumors (GTTs), combinations of etoposide, cisplatin, and either dactinomycin or bleomycin have shown promising results.[2,3] A patient who has failed primary surgical therapy is generally treated with single-agent chemotherapy unless one of the poor-prognosis factors that requires combination chemotherapy supervenes. |
| www.cancer.gov /cancertopics/pdq/treatment/gestationaltrophoblastic/healthprofessional/allpages/print (3070 words) |