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Topic: Gliadin

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	R-Biopharm AG : Allergens - Gliadin (Site not responding. Last check: 2007-10-09)
		The RIDASCREEN® Gliadin test is a sandwich enzyme immunoassay for the quantitative analysis of gliadins from wheat and corresponding prolamines from rye and barley in food.
		The proportion of glutelin to gliadin in the protein mixture is approximately the same.
		the monoclonal antibody reacts with the gliadin fraction from wheat, corresponding prolamines from rye and barley.
	www.r-biopharm.com /foodandfeed/ridascreen_gliadin.php (358 words)

	Early effects of gliadin on enterocyte intracellular signalling involved in intestinal barrier function -- Clemente et ...
		The gliadin effect on the actin cytoskeleton was reversible as two hours after withdrawal of gliadin from the culture medium the actin cytoskeleton returned to its basal state (D).
		Gliadin 0.1 mg/ml induced release of zonulin in the cell medium that peaked at 30 minutes post-gliadin incubation and returned to baseline when cells were incubated with gliadin for 60 minutes.
		The peak of gliadin induced actin polymerisation (106.8±0.5%
	gut.bmjjournals.com /cgi/content/full/52/2/218 (4241 words)

	Anti—Helicobacter Pylori Effect of Mucoadhesive Nanoparticles Bearing Amoxicillin in Experimental Gerbils Model
		Gliadin appears to be a suitable polymer for the preparation of mucoadhesive nanoparticles capable of adhering to the mucus layer.
		Gliadin nanoparticles (GNP) have shown a great tropism for the upper gastrointestinal regions, and their presence in other intestinal regions has been shown to be very low.
		Ten milligrams of gliadin formulations was incubated at 37 ± 1°C with 20 mL of SGF (pH 1.2) for 24 hours and the suspension was centrifuged at 15 000 rpm for 1 hour, the supernatant was removed, and the nanoparticles were dissolved in ethanolic solution (7:3 ratio).
	www.aapspharmscitech.org /view.asp?art=pt050232 (4340 words)

	Diagnos-Techs, Inc. - Conceptual Framework of Adrenal Stress Index, The Gliadin Antibody Test (Site not responding. Last check: 2007-10-09)
		Gliadin reactivity and intolerance is a genetically determined enteropathy, and a non IgE mediated response.
		Salivary and serum antibody to gliadin in the diagnosis of celiac disease.
		Gliadin immune reactivity is associated with overt and Latent Enteropathy in relatives of celiac patient.
	www.diagnostechs.com /body_text/tests/asi/asimonograph_new/asi_gliadinantibodytest.htm (525 words)

	The Basic Factors of Gluten Sensitivity and Celiac Disease
		Gliadin is a molecule that makes up a large part of the protein in wheat.
		As wheat protein (gluten) is digested, some of the gliadin becomes water-soluble, and is able to come in contact with human tissue.
		Because of its particular physical and chemical properties, gliadin is a large molecule that can actually cross the intestine into the blood on its own (this the very reason the adenovirus uses gliadin.) But in general, healthy intestine walls block most large molecules.
	members.cox.net /harold.kraus/gluten/the_basics.htm (1297 words)

	From viscous to viscoelastic: Rheology of vital wheat gliadin suspensions. (Site not responding. Last check: 2007-10-09)
		From viscous to viscoelastic: Rheology of vital wheat gliadin suspensions.
		Semi-concentrated to concentrated gliadin suspensions were studied from 150 mg/ml to 350 mg/ml.
		At 150 mg/ml, the storage moduli (G´) of the gliadin were in the range of 0.002 - 20 dyne/cm(^2) and phase shifts were 64 - 83 degrees.
	www.aaccnet.org /meetings/2000/Abstracts/a00ma232.htm (295 words)

	Fractionation of gliadin components from a doubled-haploid population by capillary electrophoresis. (Site not responding. Last check: 2007-10-09)
		The CE profiles of gliadins from 152 DH lines were compared to the established allelic composition for their low-molecular-weight glutenin subunits (known to be closely linked to the gliadin genes).
		As a result, it was possible to assign all 70 of the gliadin CE components to the six gliadin loci on chromosomes 1 and 6 of the three wheat genomes.
		Specific gliadin components were demonstrated to be associated with certain quality traits by combined statistical analysis of CE profiles and quality results for the 152 DH lines.
	www.aaccnet.org /meetings/2001/Abstracts/a01ma415.htm (234 words)

	[No title]
		Immune reactions to gliadin are likely to play a role in the pathogenesis of the disease since both humoral and cell-mediated responses have been demonstrated in the peripheral blood and in the gut of coeliac patients (1).
		The results for gliadin should be interpreted in conjunction with the clinical evaluation and the results of other diagnostic procedure.
		This represented two groups of specimens; 255 clinical specimens which were either sent to the lab for routine gliadin serological analysis or were part of an external gliadin study, and 50 random normal donor specimens.
	www.rapidtest.com /gliadinA_1022.doc (2750 words)

	Gliadin electrophoresis in the evaluation of Bulgarian wheat germplasm
		Gliadin electrophoresis in the evaluation of Bulgarian wheat germplasm
		The association between gliadin components was determined by cluster analysis (Euclidean distances).
		New allelic variants for gliadins were screened in landraces for incorporation into advanced breeding material.
	www.ipgri.cgiar.org /publications/pgrnewsletter/08glia.htm (107 words)

	Gliadin - Biography
		Gliadin is very kind and caring person who is somewhat flamboant at times but other times very pensive and quiet.
		Because of his slight build he is often mistaken for being a women even when he is in male clothing and has a rich baratone when he speaks normally, but he usually speaks in a husky voice that can be both male and female at the same time.
		Gliadin and any 'new' characters are the brain children of Khallandra and are created purely for the entertainment of others.
	khallandra.tripod.com /gliadin/bio.htm (408 words)

	Antibodies against Endomysium und Gliadin
		The most suitable substrates, however, are frozen sections of fetal primate intestine or stomach: in the case of a positive sample, the muscle layer as well as the lamina mucosa propria show a honeycomb-like fluorescence.
		Both anti-endomysium antibodies and antibodies against gliadin (class IgA) are reliable serological markers for an active gluten-sensitive enteropathy.
		The quantitative determination of antibodies against gliadin is very suitable for monitoring the progress of the disease, compliance with a gluten-free diet, or a gluten tolerance test.
	www.euroimmun.de /ema_aga_engl.htm (235 words)

	Gliadin and Transglutaminase Assessments
		ANTI-GLIADIN ANTIBODY, IgA: Gliadin IgA is an enzyme-linked immunosorbent assay (ELISA) for the detection of Gliadin IgA antibodies.
		ANTI-GLIADIN ANTIBODY, IgG: Gliadin IgG is an enzyme-linked immunosorbent assay (ELISA) for the detection of Gliadin IgG antibodies.
		Celiac disease and dermatitis herpetiformis, two recognized forms of gluten sensitive enteropathy (GSE) are characterized by chronic inflammation of the intestinal mucosa and flattening of the epithelium or positive "villous atrophy".
	www.biodia.com /test264.html (305 words)

	[No title] (Site not responding. Last check: 2007-10-09)
		ELISPOT responses to tTG-treated truncations of A-gliadin 56-75 (0.1
		Such a derivative is typically a fragment of the gliadin, or a mutated derivative of the whole protein or fragment.
		The plant cell of the invention is typically one which does not express a wild- type gliadin (such as any of the gliadins mentioned herein which may cause coeliac disease), or one which does not express a gliadin comprising a sequence that can be recognised by a T cell that recognises the agent.
	www.wipo.int /cgi-pct/guest/getbykey5?KEY=01/25793.010412&ELEMENT_SET=DECL (11679 words)

	The Gluten Proteins and Deamidated Soluble Wheat Protein (SWP)
		The gliadins and glutenins are the storage proteins of wheat endosperm and they tend to be rich in asparagine, glutamine, arginine or proline (Abrol et al., 1971; Derbyshire et al., 1976; Kirkman et al., 1982; Larkins, 1981; Spencer and Huggins, 1982) but very low in nutritionally important amino acids lysine, tryptophan and methionine (Appendix A).
		The gliadins are divided into four groups, called alpha-, beta-, gamma-, and omega-gliadins, based on their electrophoretic mobility at low pH (Woychick et al., 1961), but more than 30 components can be separated by two-dimensional electrophoretic procedures.
		Because of the monomeric character of alpha-type gliadins, and the absence of free sulphydryl groups, it has been assumed that the cysteine residues are linked by three intramolecular disulphide bonds (Kasarda et al., 1987).
	www.friedli.com /research/PhD/gluten/chap2.html (4706 words)

	Diagnostics tests for Celiac Disease
		There are two classes of antibodies seen in untreated celiac disease: Antibodies directed against a fragment of gluten called gliadin and antibodies directed against some tissue in the body itself, endomysial (the covering of muscle), and reticulin (the framework for kidney and liver).
		IgA gliadin antibodies increase rapidly in response to gluten in the diet and decrease rapidly when gluten is absent from the diet.
		Gliadin is a fraction of the gluten protein found in wheat and some other cereal grains.
	www.enabling.org /ia/celiac/diag-tst.html (10277 words)

	Gliadin - Wikipedia, the free encyclopedia
		Gliadin is a glycoprotein, present in wheat and some other cereals, best known for its role, along with glutenin, in the formation of gluten.
		Some people are sensitive to gliadin due to disorders such as celiac disease or Crohn's disease.
		This page was last modified 17:50, 23 March 2006.
	en.wikipedia.org /wiki/Gliadin (90 words)

	ARS \| Publication request: From Viscous to Viscoelastic: Rheology of Vital Wheat Gliadin Suspensions
		Technical Abstract: The linear rheological properties of vital wheat gliadin suspensions were investigated.
		At 150 mg/ml, the storage moduli (G') of the gliadin were in the range of 0.002-20 dyne/cm**2 and phase shifts were 64-83 deg.
		Over a narrow concentration range (250 mg/ml to 300 mg/ml), the properties of gliadin suspensions dramatically changed from viscous to viscoelastic.
	ars.usda.gov /research/publications/publications.htm?SEQ_NO_115=111578 (282 words)

	Celiac.com Celiac Disease: (Gliadin Cooked in Hot Oilï¿½ Does it Break Down?) Gluten-Free
		Gliadin is a fragment of the protein gluten.
		It is the deamidated protein within the gliadin fragment of the gluten protein that is believed to be the big trigger for the antibody response that causes damage.
		Researchers are still exploring the properties of gliadin and trying to find a way to use the molecules interactions to stop the Celiac response.
	www.celiac.com /st_prod.html?p_prodid=1034 (1057 words)

	SOD with Gliadin
		SOD with Gliadin benefits joint structure and function, respiratory system health, vision health, immune system cellular health, aging, and neurological and cardiovascular health.
		Gliadin, a wheat-based polymer, coats the SOD enzyme, protecting it f rom digestion until it reaches the intestinal tract, where it can be absorbed and utilized.
		The use of gliadin with SOD has been shown to increase absorption of SOD by up to 57 percent.
	www.soulhealer.com /1893-8.htm (413 words)

	Identification of common epitopes on gliadin, enterocytes, and calreticulin recognised by antigliadin antibodies of ...
		Identification of common epitopes on gliadin, enterocytes, and calreticulin recognised by antigliadin antibodies of patients with coeliac disease -- Krupicková et al.
		Identification of common epitopes on gliadin, enterocytes, and calreticulin recognised by antigliadin antibodies of patients with coeliac disease
		Lymphocyte activation by gliadin in celiac disease and in experimentally induced entheropathy of germ-free rats.
	gut.bmjjournals.com /cgi/content/full/44/2/168 (3158 words)

	ARS \| Publication request: Microheterogeneity and Microrheology of Wheat Gliadin Suspensions Studied by ...
		Both gliadin and glutenin are responsible for the viscoelastic properties of gluten.
		We found that the degree of heterogeneity of the suspensions, as measured by the width and skewness of the microspheres' mean squared displacement (MSD) distribution, increased dramatically over a narrow range of gliadin concentrations.
		For increasing concentrations of gliadin, the ensemble averaged MSD rapidly displayed a plateau at small time scales, the MSD distribution became wider and more asymmetric, and the local viscoelastic moduli extracted from multiple particle-tracking measurements showed an increasingly wider range.
	www.ars.usda.gov /research/publications/publications.htm?SEQ_NO_115=128279 (281 words)

	Targeting of gliadin peptides, CD8, {alpha}/ß-TCR, and {gamma}/{delta}-TCR to Golgi complexes and vacuoles within ...
		gliadin peptides in vacuoles and Golgi complexes of enterocytes.
		WB8 antibody are decreased on the apical membrane of enterocytes
		Few gliadin peptides are detected in vesicles close to the apical membrane.
	www.fasebj.org /cgi/content/full/12/13/1349 (4245 words)

	Gliadin in Foods
		The separation of prolamins in cereal grains is still carried out by classical methods of solvent extraction and the various gliadins are separated by a variety of methods involving chromatography and electrophoresis.
		The authors note that small amount of gliadin found in nominally GF foods may be important in very sensitive patients with CD when consumed on a regular basis.
		As would be expected, the toxicity of gliadin is related both to the size of dose and length of time administered.
	www.csaceliacs.org /library/gliadinfood.php (1168 words)

	Definition of the initial immunologic modifications upon in vitro gliadin challenge in the small intestine of celiac ...
		Definition of the initial immunologic modifications upon in vitro gliadin challenge in the small intestine of celiac patients.
		METHODS: Intestinal biopsy specimens (15 treated celiacs and 13 controls) were cultured with gliadin or maize prolamine digests for 24 hours as well as for 1, 2, 4, 6, 8, and 12 hours in some subjects.
		CONCLUSIONS: In vitro gliadin challenge is a suitable model to reproduce various immunologic features of celiac lesions; these may be caused by different pathways.
	www.aegis.com /aidsline/1996/aug/M9681058.html (481 words)

	ORGENTEC Diagnostika GmbH
		It is caused by a hypersensitivity reaction in response to gliadin, a protein being present in many cereals.
		This, non IgE mediated food allergy leads to massive malabsorption disturbances and is characterized by a complete atrophy of the villi and a hyperplasia of the crypts of the upper intestine.
		Gliadin antibodies titre correlate very well with the morphological appearance of the mucosa of the upper intestine.
	www.orgentec.com /cgi-bin/cj/messigent.pl?company=73&zoneid=208&pk=1348&action=show&tmplid=1 (149 words)

	Identification of transglutaminase-mediated deamidation sites in a recombinant {alpha}-gliadin by advanced ...
		Tissue transglutaminase selectively modifies gliadin peptides, that are recognized by gut-derived T cells in celiac disease.
		Identification of a gliadin T-cell epitope in coelic disease: General importance of gliadin deamidation for intestinal T-cell recognition.
		Wieser, H., Mödl, A., Seilmeier, W., and Belitz, H.D. High-perfomance liquid chromatography of gliadins from different wheat varieties: Amino acid composition and N-terminal amino acid sequence of components.
	www.proteinscience.org /cgi/content/full/12/11/2434 (3986 words)

	Heat Shock Protein and Gliadin Peptide Promote Development of Peptidase Antibodies in Children with Autism and Patients ...
		antibodies against gliadin are presented in Tables 2 and 3.
		response to membrane peptidases, SK, HSPs, and gliadin peptides
		This persistence of SK, HSP, and gliadin peptide in
	cdli.asm.org /cgi/content/full/11/3/515 (6044 words)

	Gliadin definition - Medical Dictionary definitions of popular medical terms
		Gliadin: A glycoprotein (a carbohydrate plus a protein) within gluten.
		Gliadin is found in wheat and some other grains, including oats, rye, barley, and millet.
		People with celiac disease, Crohn's disease, and other conditions may be sensitive to gliadin in the diet.
	www.medterms.com /script/main/art.asp?articlekey=11381 (178 words)

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