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Topic: Glucosamine

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	MedlinePlus Herbs and Supplements: Glucosamine
		Glucosamine sulfate is a normal constituent of glycoaminoglycans in cartilage matrix and synovial fluid.
		Glucosamine is removed from the body mainly in the urine, and elimination of glucosamine from the body is delayed in people with reduced kidney function.
		Glucosamine is not recommended during pregnancy or breastfeeding due to lack of scientific evidence.
	www.nlm.nih.gov /medlineplus/druginfo/natural/patient-glucosamine.html (2076 words)

	Glucosamine - Wikipedia, the free encyclopedia (Site not responding. Last check: 2007-09-16)
		Glucosamine is commonly used as a treatment for osteoarthritis, although its acceptance as a medical therapy varies.
		Since glucosamine is a precursor for glycosaminoglycans, and glycosaminoglycans are a major component of joint cartilage, supplemental glucosamine may help to rebuild cartilage and treat arthritis.
		Glucosamine is often sold in combination with other supplements such as chondroitin sulfate and methylsulfonylmethane.
	en.wikipedia.org /wiki/Glucosamine (1564 words)

	Vitamin Express (Site not responding. Last check: 2007-09-16)
		Glucosamine sulfate contributes to the cushioning nature of the joint fluids and surrounding tissues.
		Glucosamine sulfate appears to be one remedy that helps with both the causes and the symptoms of osteoarthritis.
		Glucosamine sulfate is a natural substance that improves a condition by addressing the underlying cause and supporting the body's natural ability to heal itself.
	www.vitaminexpress.com /article.php/content/glucosamine.php (802 words)

	Glucosamine (Site not responding. Last check: 2007-09-16)
		Glucosamine sulfate's primary biological role in halting or reversing joint degeneration appears to be directly due to its ability to act as an essential substrate for, and to stimulate the biosynthesis of, the glycosaminoglycans and the hyaluronic acid backbone needed for the formation of proteoglycans found in the structural matrix of joints.
		Glucosamine, which is formed in the body as glucosamine 6-phosphate (G6-P), is the most fundamental building block required for the biosynthesis of the classes of compounds, such as glycolipids, glycoproteins, glycosaminoglycans (formerly called mucopolysaccharides), hyaluronate and proteoglycans, requiring amino sugars.
		Glucosamine hydrochloride, glucosamine hydroiodide, and GS promoted a significant increase in the glycosaminoglycans in the extracellular cartilage matrix and induced an increase in the secretion of glycosaminoglycans from the surface of the bone cells into the culture medium.
	www.thorne.com /altmedrev/fulltext/gluco3-1.html (5645 words)

	Glucosamine
		Glucosamine is a chemical compound of Glucose and an Amine molecule (a nitrogen atom with two hydrogen atoms) that supports the maintenance of cartilage and the connective tissues in the body.
		Glucosamine is among the most popular joint supplements – and at 1500mg per day appears to be quite safe and effective – but approximately 4-8 eight weeks may be necessary before the joint benefits of glucosamine become evident.
		Glucosamine and chondroitin sulfate supplements are used to slow the progression of osteoarthritis — the deterioration of cartilage between joint bones — and reduce associated pain.
	www.usgyms.net /glucosamine.htm (1335 words)

	Glucosamine - Supplements
		Glucosamine is an aminopolysaccharide (a combination of an amino acid - glutamine and a sugar - glucose).
		Glucosamine is concentrated in joint cartilage where it is incorporated in longer chains known as glycosaminoglycans and finally into very large structures known as proteoglycans.
		The principle behind glucosamine supplementation is that the glucosamine is delivered to the joint space and incorporated into proteoglycans of joint cartilage to maintain structure and repair damage.
	www.supplementwatch.com /supatoz/supplement.asp?supplementId=145 (709 words)

	Glucosamine\| Glucosamine Side Effects
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	www.geocities.com /glucosamines3 (755 words)

	National Nutritional Foods Association:
		Glucosamine, which the body synthesizes from glucose and glutamine, is the key precursor for all of the glycosaminoglycans and comprises 50% of hyaluronic acid.
		Glucosamine is typically prepared from shellfish, specifically from chitin, the major indigestible carbohydrate in the shells of crustaceans (e.g.
		In a long-term (3 year) study of glucosamine sulfate in knee osteoarthritis, radiography was used to determine structural changes in the knee joint and pain reduction was assessed in comparing a single daily dose of 1500mg glucosamine to placebo.
	www.nnfa.org /site/PageServer?pagename=rr_bg_glucosamine (1964 words)

	Glucosamine
		Glucosamine is an amino monosaccharide found in chitin, glycoproteins and glycosaminoglycans (formerly known as mucopolysaccharides) such as hyaluronic acid and heparan sulfate.
		In the case of glucosamine hydrochloride, the anion is chloride, and in glucosamine sulfate the anion is sulfate.
		In another recent meta-analysis of nine randomized, controlled trials of glucosamine, glucosamine was significantly superior to placebo in seven of the studies and was superior to ibuprofen and equal to ibuprofen in the other two studies.
	www.pdrhealth.com /drug_info/nmdrugprofiles/nutsupdrugs/glu_0122.shtml (1587 words)

	Herbal America ¿ Glucosamine Arthritis Pain relief Supplement (Site not responding. Last check: 2007-09-16)
		Glucosamine is a very promising treatment for Arthritis and is backed by many double blind, placebo-controlled studies.
		Glucosamine makes Synovial fluid thick and gelatinous, which allows it to hold more water; this increases its cushioning ability, thus, Glucosamine has the ability to decrease friction and pain in the joint.
		Although Glucosamine is biochemically classed as a carbohydrate (sugar), the body is not able to break it down into glucose, so Glucosamine does not raise blood sugar by providing an additional source of glucose.
	www.herbalamerica.com /glucosamine.html (999 words)

	Glucosamine and Chondroitin Sulfate
		Glucosamine and chondroitin sulfate are substances found naturally in the body.
		Glucosamine is a form of amino sugar that is believed to play a role in cartilage formation and repair.
		They are extracted from animal tissue: glucosamine from crab, lobster or shrimp shells; and chondroitin sulfate from animal cartilage, such as tracheas or shark cartilage.
	www.arthritis.org /conditions/alttherapies/glucosamine.asp (585 words)

	Glucosamine definition - Arthritis and arthritic conditions, medications, and treatment on MedicineNet.com
		Glucosamine: A molecule derived from the sugar glucose by the addition of an amino (NH2) group, glucosamine is a component of a number of structures including the blood group substances and cartilage.
		Glucosamine may improve symptoms of pain and stiffness in some patients with osteoarthritis, according to recent research studies.
		Glucosamine has been marketed as a "cartilage rebuilder." This is in part under the assumption that, because glucosamine is a component of normal cartilage, consuming it will assist in the rebuilding of damaged cartilage.
	www.medterms.com /script/main/art.asp?articlekey=7163 (327 words)

	Glucosamine Sulfate and Chondroitin Sulfate
		Glucosamine sulfate has a relatively low molecular weight and is the sulfate salt of the natural aminomonosaccharide, glucosamine.
		In a recent 3-year, randomized, placebo-controlled, prospective study by Bruyere et al, 212 patients with knee OA were evaluated to determine the effect of glucosamine and chondroitin on symptom and structure modification in knee OA (12).
		In patients who had mild OA and were in the highest quartile of baseline mean joint space narrowing, glucosamine was associated with a trend (p=0.10) towards a significant reduction in joint space narrowing (13).
	www.arthritis.org /research/bulletin/vol52no12/glucosamine.asp (793 words)

	Glucosamine (Site not responding. Last check: 2007-09-16)
		Participants were randomly assigned to receive one of five treatments daily for 24 weeks: glucosamine alone (500 milligrams three times a day), chondroitin sulfate alone (400 milligrams three times a day), glucosamine and chondroitin combined (at those same doses), a placebo (dummy pill), or Celebrex (a prescription drug approved for arthritis pain).
		While it has been shown that glucosamine can be absorbed and attaches to cartilage, many researchers believe that chondroitin sulfate supplements cannot be absorbed.
		Some think that glucosamine may make it harder for the body to process blood sugar and thus may be a problem for diabetics.
	www.berkeleywellness.com /html/ds/dsGlucosamine.php (1202 words)

	Cheap glucosamine - online pharmacy. Buy glucosamine from discount store - A Bravenet.com Guestbook
		Glucosamine is a molecule made of glucose and an amine that is produced naturally in the body.
		Glucosamine is an amino sugar produced from the shells of shellfish (chitin.
		glucosamine glucosamine V glucosamine Seventies he was the absence of adequate procedures glucosamine obtaining amendments to the wide range of National Occupational Standards for National Vocational Qualifications.
	pub42.bravenet.com /guestbook/3523681382 (1025 words)

	Glucosamine
		Glucosamine, which occurs naturally in the body, plays a key role in the construction of cartilage -- the tough connective tissue that cushions the joints.
		Glucosamine may be effective in treating and possibly slowing the progression of osteoarthritis.
		Although glucosamine and chondroitin are often administered together for the treatment of osteoarthritis, it is not clear that the combination works better than either supplement alone.
	www.umm.edu /altmed/ConsSupplements/Glucosaminecs.html (1402 words)

	Glucosamine and Chondroitin-Topic Overview
		Glucosamine and chondroitin are part of normal cartilage.
		Glucosamine, also called chitosamine, is a natural substance that is found in the covering of shellfish.
		Glucosamine and chondroitin are available in tablet, capsule, powder, or liquid form and are often taken in combination with each other or in combination with other dietary supplements.
	arthritis.webmd.com /tc/Glucosamine-and-Chondroitin-Topic-Overview (625 words)

	Glucosamine : by Ray Sahelian, M.D., glucosamine and chondroitin information, glucosamine sulfate for arthritis
		Glucosamine is made from the combination of a sugar - hence the first part of the name glucos(e) - and an amine, which is a derivative of ammonia containing nitrogen (N) and hydrogen (H) atoms.
		Glucosamine is derived from shrimp, oyster and crab shells and chondroitin is derived from cartilage of cows, pigs, and sharks.
		At baseline, glucosamine sulfate and placebo groups were comparable for demographic and disease characteristics, both in the general population and in the postmenopausal women subset.
	www.raysahelian.com /glucosamine.html (7161 words)

	Is glucosamine an effective treatment for osteoarthritic pain?
		Glucosamine is an intermediate substrate in the synthesis of the ground substance (non-collagen portion) of cartilage.
		In three of the studies, at least one of the authors was affiliated with the glucosamine manufacturer, and in one of those studies, patients were included in the study who had minimal (grade I) joint changes that were not definitively osteoarthritis.
		Although no study has addressed the correct dose of glucosamine or the actual time to onset of pain relief, the human clinical trials seem to suggest that a 12-week course of treatment is required at a dosage of 500 mg three times a day.
	www.clevelandclinicmeded.com /ccjm/June2001/hooper.htm (1007 words)

	GLUCOSAMINE
		Glucosamine sulfate's role in halting or reversing joint degeneration appears to be directly due to its ability to act as an essential substrate for, and to stimulate the biosynthesis of, the glycosaminoglycans and the hyaluronic acid backbone needed for the formation of the proteoglycans found in the structural matrix of joints.
		Glucosamine sulfate's primary biological role in halting or reversing joint degeneration appears to be directly due to its ability to act as an essential substrate for, and to stimulate the biosynthesis of, the glycosaminoglycans and the hyaluronic acid backbone needed for the formation of proteoglycans found in the structural matrix of joints.
		Before we discuss which form of glucosamine to use, we must answer the question, "Does glucosamine work?" Although the answer may seem obvious to those of us in the chiropractic and nutrition communities, many scientists and doctors do not feel glucosamine supplementation is beneficial for arthritis and related connective tissue dysfunction.
	www.chiro.org /nutrition/glucosamine.shtml (2885 words)

	Glucosamine - Herbs & Supplements - Drug Library - DrugDigest
		Most of the clinical studies investigating glucosamine’s medical effects have used a salt known as glucosamine sulfate, but other salts such as glucosamine hydrochloride and n-acetyl glucosamine are also sold widely.
		Although glucosamine has been studied most for treating OA of large joints such as knees and hips, it has also showed some effectiveness for relieving arthritis in other joints such as the jaw, which is also known as the temporomandibular joint (TMJ).
		In a few studies, participants who began taking supplemental glucosamine before surgery and continued taking it until their incisions were completely healed showed generally faster healing with less scarring than other participants who did not take glucosamine.
	www.drugdigest.org /DD/DVH/HerbsWho/0,3923,4055\|Glucosamine,00.html (650 words)

	Glucosamine
		Glucosamine is an important building block needed by the body to manufacture specialized molecules called glycosaminoglycans, found in cartilage.
		The glucosamine sulfate (GS) form (stabilized with a mineral salt) is the only form clearly shown in clinical trials to be effective for osteoarthritis.
		Until more is known, people taking glucosamine supplements for long periods may wish to have their blood sugar levels checked; people with diabetes should consult with a doctor before taking glucosamine and should have blood sugar levels monitored if they are taking glucosamine.
	www.puritan.com /vf/healthnotes/HN75_english/Supp/Glucosamine.htm (828 words)

	Glucosamine for Arthritis: The Evidence Is Conflicting
		Glucosamine supplements are derived from shellfish shells; chondroitin supplements are generally made from cow cartilage.
		Trials of glucosamine and chondroitin preparations for OA symptoms demonstrate moderate to large effects, but quality issues and likely publication bias suggest that these effects are exaggerated.
		Glucosamine with or without chondroitin may have some beneficial effect on osteoarthritis, and studies up to 3 years in duration have found no more adverse effects than with placebo, but most Medical Letter consultants are skeptical.
	www.quackwatch.com /01QuackeryRelatedTopics/DSH/glucosamine.html (1815 words)

	Glucosamine For Dogs, Syn-flex, Hips, Joints, Pets
		Glucosamine is clinically proven to be highly beneficial in the treatment of osteoarthritis.
		Glucosamine has been clinically proven to not only halt the progress of OA, even more importantly it will actually begin the process of rehabilitating and reversing the damage that has already been done.
		Glucosamine is a compound that has been heavily touted recently as the "cure" for osteoarthritis.
	www.pestproducts.com /glucosamine_for_pets.htm (1285 words)

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