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Topic: Glucose transporter

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	Glucose Transporter Families SGLT and GLUT: Molecular Basis of Normal and Aberrant Function, The JPEN: Journal of ... (Site not responding. Last check: 2007-10-13)
		Furthermore, several congenital defects of sugar metabolism are caused by aberrant transporter genes (eg, the glucose-galactose malabsorption syndrome, SGLT1; the glucose transporter 1 deficiency syndrome; and the Fanconi-Bickel syndrome, GLUT2).
		Because the lipid bilayer of the eucaryotic plasma membrane is impermeable for hydrophilic molecules, glucose is transported across the plasma membrane by membrane associated carrier proteins, glucose transporters.
		The sodium-dependent glucose transporters, also known as co-transporters or symporters, are integral membrane proteins that mediate the transport of glucose and, with much lower affinity, galactose across the plasma membrane by an active transport mechanism.15 This transport process is a cotransport of glucose molecules and sodium ions.
	www.findarticles.com /p/articles/mi_qa3762/is_200409/ai_n9454290 (672 words)

	Glucose transporter - Wikipedia, the free encyclopedia
		Glucose transporters (GLUT or SLC2A family) are a family of membrane proteins found in most mammalian cells.
		Transport of glucose through the apical membrane of intestinal and kidney epithelial cells depends on the presence of secondary active Na+/glucose symporters, SGLT-1 and SGLT-2, which concentrate glucose inside the cells, using the energy provided by cotransport of Na+ ions down their electrochemical gradient.
		Facilitated diffusion of glucose through the cellular membrane is otherwise catalyzed by glucose carriers (protein symbol GLUT, gene symbol SLC2 for Solute Carrier Family 2) that belong to a superfamily of transport facilitators (major facilitator superfamily) including organic anion and cation transporters, yeast hexose transporter, plant hexose/proton symporters, and bacterial sugar/proton symporters.
	en.wikipedia.org /wiki/Glucose_transporter (546 words)

	Feedback Regulation of Glucose Transporter Gene Transcription in Kluyveromyces lactis by Glucose Uptake -- Milkowski et ...
		Glucose concentrations in the culture supernatants were determined by using the glucose oxidase/peroxidase assay (3).
		glucose uptake and the glucose response of gene expression is
		Glucose uptake in Kluyveromyces lactis: role of the HGT1 gene in glucose transport.
	jb.asm.org /cgi/content/full/183/18/5223 (4125 words)

	Regulation of Glucose Transport in the NIH 3T3 L1 Preadipocyte Cell Line by TCDD
		Percent inhibition of glucose transport by TCDD was greater in the presence of 13.3 mM cold D-glucose than in the absence of cold D-glucose.
		Enan E, Liu PCC, Matsumura F. 2,3,7,8-tetrachlorodibenzo-p-dioxin causes reduction in glucose transporting activities in the plasma membranes of adipose tissue and pancreas from the guinea pig.
		Hexose transport stimulation and membrane redistribution of glucose transporter isoforms in response to cholera toxin, dibutyryl cyclic AMP, and insulin in 3T3-L1 adipocytes.
	www.ehponline.org /members/1994/102-5/olsen-full.html (3805 words)

	Insulin resistance and glucose transporter expression during the euglycemic hyperinsulinemic clamp in the lamb -- ...
		Insulin resistance and glucose transporter expression during the euglycemic hyperinsulinemic clamp in the lamb -- Gelardi et al.
		The contribution of glucose to neonatal glucose homeostasis in the lamb.
		-ATPase subunits in transgenic mice overexpressing the GLUT4 glucose transporter.
	ajpendo.physiology.org /cgi/content/full/277/6/E1142 (4106 words)

	Impaired Glucose Transporter Activity in Pressure-Overload Hypertrophy Is an Early Indicator of Progression to Failure ...
		Glucose transporters and in vivo glucose uptake in skeletal and cardiac muscle: fasting, insulin stimulation and immunoisolation studies of Glut-1 and Glut-4.
		Translocation of the glucose transporter Glut-4 in cardiac myocytes of the rat.
		Pretranslational suppression of a glucose transporter protein causes insulin resistance in adipocytes from patients with non-insulin-dependent diabetes mellitus and obesity.
	circ.ahajournals.org /cgi/content/full/100/suppl_2/II-187 (3633 words)

	InterPro: IPR000803 Facilitated glucose transporter (Site not responding. Last check: 2007-10-13)
		The ability to transport glucose across the plasma membrane is a feature common to nearly all cells, from simple bacteria through to highly specialised mammalian neurones.
		Facilitative sugar transport is mediated by members of the GLUT transporter family, which form an aqueous pore across the membrane through which sugars can move in a passive (i.e., energy-independent) manner; in consequence, they can only transport sugars down their concentration gradient.
		In the GLUT transporters, this motif is present in the presumed cytoplasmic loops connecting TM domains 2 with 3, and also 8 with 9.
	www.ebi.ac.uk /interpro/IEntry?ac=IPR000803 (3388 words)

	Time-dependent physiological regulation of ovine placental GLUT-3 glucose transporter protein -- Das et al. 279 (6): ...
		We immunolocalized the GLUT-3 glucose transporter isoform versus GLUT-1 in the late-gestation epitheliochorial ovine placenta,
		and transport by the placenta in response to acute and chronic
		Placental glucose transporter gene expression and metabolism in the rat.
	ajpregu.physiology.org /cgi/content/full/279/6/R2252 (5637 words)

	Glucose Transporter Proteins in Human Insulinoma -- Boden et al. 121 (2): 109 -- Annals of Internal Medicine
		glucose transporter of islets of Langerhans is functionally similar to the low affinity transporter of liver and has an identical primary sequence.
		Role of protein kinase C in the regulation of glucose transport in rat adipose cell.
		Elevated levels of glucose transport and transporter messenger RNA are induced by ras or src oncogenes.
	www.annals.org /cgi/content/full/121/2/109 (2325 words)

	Sequence and structure of a human glucose transporter -- Mueckler et al. 229 (4717): 941 -- Science
		The amino acid sequence of the glucose transport protein from human HepG2 hepatoma cells was deduced from analysis of a complementary DNA clone.
		Structural analysis of the purified human erythrocyte glucose transporter by fast atom bombardment mapping and gas phase Edman degradation confirmed the identity of the clone and demonstrated that the HepG2 and erythrocyte transporters are highly homologous and may be identical.
		Relative Proximity and Orientation of Helices 4 and 8 of the GLUT1 Glucose Transporter.
	www.sciencemag.org /cgi/content/abstract/229/4717/941 (2129 words)

	Glucozene-Rx 30cp for Glucose Management
		Studies indicate that this supplement may also be a viable herbal alternative to regulate glucose levels through its use of corosolic acid and chlorogenic acid and also possibly aid in weight loss.
		The fat cells are converted to glycerol and glucose by the liver and are released into the blood as the second part of the blood sugar regulatory mechanism.
		Chlorogenic Acid’s Impact on Insulin - When the concentration of glucose in the blood is higher than 1g/1 because of the sugar contribution through consumption or by poor regulation of glycemia by the liver, the pancreas responds by secreting insulin.
	www.netnutri.com /browse.cfm/4,2474.htm (831 words)

	Glucose Transporter Expression in Rat Embryo and Uterus During Decidualization, Implantation, and Early ...
		Glucose Transporter Expression in Rat Embryo and Uterus During Decidualization, Implantation, and Early Postimplantation -- Korgun et al.
		The glucose transporter expression of the uterus roughly
		Prenatal expression of the GLUT4 glucose transporter in the mouse.
	www.biolreprod.org /cgi/content/full/65/5/1364 (3927 words)

	Glucose Transporter GLUT3 in the Rat Placental Barrier: A Possible Machinery for the Transplacental Transfer of Glucose ...
		Glucose Transporter GLUT3 in the Rat Placental Barrier: A Possible Machinery for the Transplacental Transfer of Glucose -- Shin et al.
		Takata K 1994 Structural basis of glucose transport in the placental barrier: role of GLUT1 and the gap junction.
		Transplacental Uptake of Glucose Is Decreased in Embryonic Lethal Connexin26-deficient Mice
	endo.endojournals.org /cgi/content/full/138/9/3997 (4678 words)

	InterPro: IPR005828 General substrate transporter
		Recent genome-sequencing data and a wealth of biochemical and molecular genetic investigations have revealed the occurrence of dozens of families of primary and secondary transporters.
		While ABC family permeases are in general multicomponent primary active transporters, capable of transporting both small molecules and macromolecules in response to ATP hydrolysis the MFS transporters are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients.
		Although well over 100 families of transporters have now been recognized and classified, the ABC superfamily and MFS account for nearly half of the solute transporters encoded within the genomes of microorganisms.
	www.ebi.ac.uk /interpro/IEntry?ac=IPR005828 (3185 words)

	Implications of Glucose Transporter Protein Type 1 (GLUT1)-Haplodeficiency in Embryonic Stem Cells for Their Survival ...
		of this transporter in response to inhibition of oxidative phosphorylation.
		Kumagai AK, Dwyer KJ, Pardridge WM: Differential glycosylation of the GLUT1 glucose transporter in brain capillaries and choroid plexus.
		Moley KH, Mueckler MM: Glucose transport and apoptosis.
	ajp.amjpathol.org /cgi/content/full/163/5/1873 (7899 words)

	Identification of a novel glucose transporter-like protein---GLUT-12 -- Rogers et al. 282 (3): E733 -- AJP - ...
		Facilitative glucose transporters exhibit variable hexose affinity and tissue-specific expression.
		Glucose is an essential energy-yielding substrate for cancer cells, and there are several instances in which known transporters
		Phosphorylation of the glucose transporter in rat adipocytes: identification of the intracellular domain at the carboxyl terminus as a target for phosphorylation in intact cells and in vitro.
	ajpendo.physiology.org /cgi/content/full/282/3/E733 (3005 words)

	GLUT4 glucose transporter deficiency increases hepatic lipid production and peripheral lipid utilization -- Kotani et ...
		Blood glucose was determined in the tail vein at 0, 15, 30, 45, 60, and 90 minutes.
		Shepherd, P.R., and Kahn, B.B. Glucose transporters and insulin action--implications for insulin resistance and diabetes mellitus.
		Chin, E., Zhou, J., and Bondy, C. Anatomical and developmental patterns of facilitative glucose transporter gene expression in the rat kidney.
	www.jci.org /cgi/content/full/114/11/1666 (6941 words)

	Glucose Transporter (Gluts1-13) Antibodies
		Molecular cloning of these glucose transporters has identified a family of closely related genes that encodes at least 9 proteins (Glut-1 to Glut-14, Mol.
		mediates glucose transport into red cells, and throughout the blood brain barrier.
		It is ubiquitously expressed and transport glucose in most cells.
	www.4adi.com /flr/glutsflr.html (622 words)

	Glucose transporter GLUT3: Ontogeny, targeting, and role in the mouse blastocyst -- Pantaleon et al. 94 (8): 3795 -- ...
		Glucose transporter GLUT3: Ontogeny, targeting, and role in the mouse blastocyst -- Pantaleon et al.
		Glucose transporter GLUT3: Ontogeny, targeting, and role in the mouse blastocyst
		Glucose Transporter 8 Expression and Translocation Are Critical for Murine Blastocyst Survival
	www.pnas.org /cgi/content/abstract/94/8/3795 (1259 words)

	Sodium-Coupled Glucose Transporter as a Functional Glucose Sensor of Retinal Microvascular Circulation -- Wakisaka et ...
		Glucose uptake through SGLT2 was calculated as described in Materials and Methods.
		Glucose entry into rat mesangial cell is mediated by both Na-coupled and facilitative transporters.
		Increase in diacylglycerol mass in isolated glomeruli by glucose from de novo synthesis of glycerolipids.
	circres.ahajournals.org /cgi/content/full/88/11/1183 (2984 words)

	Glucose transporter isoform 4 is expressed in the syncytiotrophoblast of first trimester human placenta -- Ericsson et ...
		Glucose transporter isoform 4 is expressed in the syncytiotrophoblast of first trimester human placenta -- Ericsson et al.
		Glucose transporter isoform 4 is expressed in the syncytiotrophoblast of first trimester human placenta
		1 h) on glucose uptake were studied in villous fragments.
	humrep.oxfordjournals.org /cgi/content/abstract/20/2/521 (312 words)

	Regulation of glucose-transporter function -- Kasanicki and Pilch 13 (3): 219 -- Diabetes Care (Site not responding. Last check: 2007-10-13)
		Glucose transport in mammals is mediated by a multigene family whose
		Glucose Transport in Cultured Animal Cells: An Exercise for the Undergraduate Cell Biology Laboratory
		Regulation of glucose transporter GLUT-4 and hexokinase II gene transcription by insulin and epinephrine
	care.diabetesjournals.org /cgi/content/abstract/13/3/219 (654 words)

	UniProtKB/Swiss-Prot entry Q9NRM0 [GTR9_HUMAN] Solute carrier family 2, facilitated glucose transporter member 9
		Phay J.E. Hussain H.B. Moley J.F. "Cloning and expression analysis of a novel member of the facilitative glucose transporter family, SLC2A9 (GLUT9).";
		Biological process: glucose transport (non-traceable author statement from UniProtKB).
		Solute carrier family 2, facilitated glucose transporter member 9.
	www.expasy.org /uniprot/Q9NRM0 (281 words)

	SLC2A2 - solute carrier family 2 (facilitated glucose transporter), member 2
		solute carrier family 2 (facilitated glucose transporter), member 2
		Glucose transporter 2 isoform is an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium.
		Because of its low affinity for glucose, it has been suggested as a glucose sensor.
	www.ucsf.edu /urogene/kgdb/gene/12.html (135 words)

	GLUT-4 (Glucose Transporter-4) antibodies from Research Diagnostics Inc
		It also recognizes the mouse and human GLUT-4 but shows no cross-reactivity to Hep G2 type transporter from rat brain or other Glucose transporters.
		SPECIFICITY The affinity purified antisera is specific for human glucose transporter-4 from muscle and adipose tissue.
		The molecular weight of the glucose transporter precipitated by the serum is approximately 46 kDa.
	www.researchd.com /insulin/glut4ab.htm (447 words)

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