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Topic: Glyburide

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	glyburide
		The negative aspects of first-generation sulfonylurea therapy during pregnancy may not be applicable to second-generation sulfonylureas such as glyburide and glipizide.
		The incidence of macrosomia between the groups was similar; 11% in the glyburide group and 10% in the insulin group.
		The cord serum of all infants was measured for the presence of glyburide; however, the drug was not detected in any of the infants.
	www.uic.edu /pharmacy/services/di/glyburid.htm (479 words)

	iahrOnline.org - Indian Academy of Human Reproduction (Site not responding. Last check: 2007-11-06)
		Glyburide (glibenclamide) is a sulfonylurea drug used to lower blood sugar level in patients with type II diabetes (non-insulin-dependent).
		Glyburide (glybenclamide): It is a second generation sufonylurea that does not cross the placenta, is appealing because of it apparent safety to the fetus.
		Is glyburide safe to use for gestational diabetes?: The second generation sulfonylurea, glyburide is emerging as the drug of choice for treatment of gestational diabetes, and insulin reserved only for those very few remaining refractory to glyburide.
	www.iahronline.org /ar20040429_02b.php (2432 words)

	Glyburide
		Glyburide is an oral antidiabetic medication used to treat type 2 diabetes, the kind that occurs when the body either does not make enough insulin or fails to use insulin properly.
		Glyburide is not an oral form of insulin, and cannot be used in place of insulin.
		Glyburide, like all oral antidiabetics, may cause hypoglycemia especially in elderly, weak, and undernourished people, and those with kidney, liver, adrenal, or pituitary gland problems.
	www.mymedications.net /glyburide.php (614 words)

	Glyburide detail at IndyaPharma (Site not responding. Last check: 2007-11-06)
		Glyburide is a white, crystalline compound, formulated as Glynase Prestab tablets of 1.5, 3, and 6 mg strengths for oral administration.
		Glyburide appears to lower the blood glucose acutely by stimulating the release of insulin from the pancreas, an effect dependent upon functioning beta cells in the pancreatic islets.
		Glyburide tablets are indicated as an adjunct to diet to lower the blood glucose in patients with non-insulin-dependent diabetes mellitus (Type II) whose hyperglycemia cannot be satisfactorily controlled by diet alone.
	www.indyapharma.com /Glyburide-detail.htm (4181 words)

	KFOG - Kerala Federation of Obstetrics and Gynecology (Site not responding. Last check: 2007-11-06)
		The glyburide and insulin groups were similar at baseline in age and other demographic and clinical variables.
		Glyburide appears to be a safe and effective alternative to insulin therapy in women with mild gestational diabetes.
		Concerns of teratogenicity with glyburide appear to be unfounded, given that no drug was found in the cord blood and also the therapy was started only after 11 weeks of gestation.
	www.kfog.org /ar20030806_01a.php (1933 words)

	Glucovance Online, Description, Chemistry, Ingredients - Glyburide and Metformin - RxList Monographs
		Glyburide is an oral antihyperglycemic drug of the sulfonylurea class.
		Glyburide is a white to off-white crystalline compound with a molecular formula of C
		GLUCOVANCE is available for oral administration in tablets containing 1.25 mg glyburide with 250 mg metformin hydrochloride, 2.5 mg glyburide with 500 mg metformin hydrochloride, and 5 mg glyburide with 500 mg metformin hydrochloride.
	www.rxlist.com /cgi/generic2/glucovance.htm (346 words)

	Diabeta (Glyburide) , NursingDiabetics.com, Your Total Diabetes Resource
		Diabeta (Glyburide) clinical pharmacology :druginfonet:"Glyburide appears to lower the blood glucose acutely by stimulating the release of insulin from the pancreas, an effect dependent upon functioning beta cells in the pancreatic islets.
		Diabeta (Glyburide) drug class and mechanism :focusondiabetes:"Glyburide is an oral glucose lowering-drug in a class of diabetes medicines called sulfonylureas.
		Diabeta (Glyburide) advanced consumer information :drugs.com:"Sulfonylurea antidiabetic agents (also known as sulfonylureas) are used to treat a certain type of diabetes mellitus (sugar diabetes) called type 2 diabetes.
	www.nursingdiabetics.com /diabeta.glyburide.html (1318 words)

	glyburide - [Medication]
		Treatment with glyburide may increase the risk of death from cardiovascular disease compared to treatment of diabetes with diet alone or diet plus insulin.
		Glyburide is usually taken before breakfast or the first main meal if it is taken once a day, or before meals if it is taken multiple times each day.
		Low blood sugar may occur when too much glyburide is taken; when meals are missed or delayed; if you exercise more than usual; during illness, especially with vomiting or diarrhea; if you take other medications; after drinking alcohol; and in other situations.
	www.peacehealth.org /kbase/multum/d00248a1.htm (1440 words)

	MedlinePlus Drug Information: Glyburide and Metformin
		Glyburide belongs to a class of drugs called sulfonylureas, and metformin is in a class of drugs called biguanides.
		Glyburide and metformin are not used to treat type 1 (insulin-dependent) diabetes (formerly called 'juvenile-onset').
		Glyburide and metformin are used to control the amount of sugar (glucose) in your blood.
	www.nlm.nih.gov /medlineplus/druginfo/medmaster/a699055.html (1296 words)

	glyburide - Diabetes Mellitus, Type 2, Type 1, and Metabolic Disorders treatment and medications
		Glyburide lowers the sugar level by stimulating insulin secretion in the pancreas.
		Since glyburide is metabolized by the liver and excreted by the kidneys, dosages may need to be lowered in patients with liver or kidney dysfunction.
		Therefore, glyburide must be used cautiously in patients with kidney or liver problems, and those with poor food intake, using alcohol, or participating in heavy exercise, as well as in patients taking other glucose-lowering drugs.
	www.medicinenet.com /glyburide/article.htm (510 words)

	Generic Glyburide for Type 2 diabetes - Drug Information (Site not responding. Last check: 2007-11-06)
		Glyburide is indicated as an adjunct to diet to lower the blood glucose in patients with non-insulin dependent diabetes mellitus (Type II) whose hyperglycemia cannot be controlled by diet alone.
		The most common Glyburide Side Effects are seizures, loss of consciousness, skin rash, itching or redness, exaggerated sunburn, yellowing of the skin or eyes, light-colored stools, dark urine, unusual bleeding or bruising, fever and sore throat.
		Glyburide product name, whether or not appearing in large print or with the trademark symbol, are trademarks of Aventis Pharmaceuticals.
	www.buygenericglyburide.com (500 words)

	Glyburide Information from Drugs.com
		Glyburide is in the FDA pregnancy category C. This means that it is not known whether glyburide will be harmful to an unborn baby.
		Glyburide is usually taken before breakfast if it is taken once a day, or before meals if it is taken multiple times each day.
		Increased blood sugar may occur when not enough glyburide is taken; if you eat significantly more food then usual; if you exercise less than usual; if you take other medications; during fever or other illness; and in other situations.
	www.drugs.com /glyburide.html (1430 words)

	Micronase Online, Description, Chemistry, Ingredients - Glyburide - RxList Monographs
		MICRONASE Tablets contain glyburide, which is an oral blood-glucose-lowering drug of the sulfonyl-urea class.
		Glyburide is a white, crystalline compound, formulated as MICRONASE Tablets of 1.25, 2.5, and 5 mg strengths for oral administration.
		The chemical name for glyburide is 1-[[p-[2-(5-chloro-o-anisamido)-ethyl]phenyl]-sulfo-nyl]-3-cyclohexylurea and the molecular weight is 493.99.
	www.rxlist.com /cgi/generic/glybur.htm (201 words)

	Glyburide (Site not responding. Last check: 2007-11-06)
		Glyburide affects chemicals in the brain that may become unbalanced and cause depression or mood disturbances, eating disorders, or obsessive or compulsive symptoms.
		Glyburide is also used to treat premenstrual dysphoric disorder (PMDD), symptoms of which occur in the week or two before a woman's menstrual period and commonly include irritability, mood swings, and tension as well as the physical symptoms of bloating and breast tenderness.
		• Glyburide is in the FDA pregnancy category C. Babies exposed to Glyburide and/ or other drugs of the same class during the third trimester of pregnancy may develop medical complications.
	drugs.eclub.lv /drug/Glyburide.html (1204 words)

	Drug Directory: Glyburide and metformin (Site not responding. Last check: 2007-11-06)
		Glyburide and metformin is used with diet and exercise to treat non-insulin-dependent (type 2) diabetes.
		Glyburide and metformin is in the FDA pregnancy category B. This means that it is unlikely to harm an unborn baby.
		Take glyburide and metformin with a meal to reduce nausea, diarrhea, and upset stomach that may occur with glyburide and metformin therapy.
	netpediatrics.com /drugs/g-25.htm (1322 words)

	MedlinePlus Drug Information: Glyburide and Metformin (Systemic) (Site not responding. Last check: 2007-11-06)
		Glyburide stimulates the release of insulin from the pancreas, directing your body to store blood sugar.
		Glyburide and metformin combination should be taken with meals to help reduce the gastrointestinal side effects that may occur during the first few weeks of treatment.
		Adults: At first, 2.5 mg of glyburide and 500 mg of metformin or 5 mg of glyburide and 500 mg of metformin two times a day, with the morning and evening meals.
	www.nlm.nih.gov /medlineplus/druginfo/uspdi/500237.html (2049 words)

	A Novel Extractionless HPLC Fluorescence Method for the Determination of Glyburide in the Human Plasma: Application to ...
		Standard curves of glyburide in plasma were constructed on eleven different days over a four weeks period to determine the variability of the slopes and intercepts.
		The absolute recovery of glyburide was determined by comparing the peak area of the drug obtained from the plasma with peak area obtained by the direct injection of pure aqueous drug standard at three different concentrations on three occasions.
		The bioequivalency of two glyburide products, reference and generic formulation was compared in 26 healthy male volunteers who received a single 5 mg oral dose in crossover design.
	www.ualberta.ca /~csps/JPPS4(2)/J.Khatri/HPLC.htm (2189 words)

	glyburide and metformin
		Glyburide and metformin is used with diet and exercise to treat type 2 diabetes.
		Tell your doctor that you are taking glyburide and metformin if you become ill; if you have a heart attack; have a stroke; develop congestive heart failure; experience diarrhea, vomiting, fever, or dehydration from any cause; decrease the amount of food or liquid in your normal diet, or develop other health conditions.
		Stop taking glyburide and metformin and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives) to glyburide and metformin.
	www.subscriberx.com /.SRX?Service=SRXLeaflet&Function=GetLeaflet&DrugId=37866&Dialect=English (1548 words)

	MedlinePlus Drug Information: Glyburide
		Glyburide is used to treat type 2 (noninsulin-dependent) diabetes (formerly 'adult-onset'), particularly in people whose diabetes cannot be controlled by diet alone.
		Glyburide lowers blood sugar by stimulating the pancreas to secrete insulin and helping the body use insulin efficiently.
		Glyburide is not used to treat type 1 (insulin-dependent) diabetes (formerly 'juvenile-onset').
	www.nlm.nih.gov /medlineplus/druginfo/medmaster/a684058.html (888 words)

	VitaminShoppe.com - Health Guide - Glyburide (Site not responding. Last check: 2007-11-06)
		Glyburide is a sulfonylurea drug used to lower blood sugar levels in people with type 2 (non-insulin-dependent) diabetes.
		Previously, glyburide by itself had not effectively controlled the diabetes in the people in this study.
		Glyburide may be taken with food to avoid gastrointestinal (GI) upset.
	www.vitaminshoppe.com /learning/healthguide/healthguide_content.jhtml?Category=Drug&title=Glyburide&relativePath=/content/healthnotes/Drug/Glyburide.htm (843 words)

	Glyburide - Canada Pharmacy Direct (Site not responding. Last check: 2007-11-06)
		Glyburide is used in the treatment of diabetes.
		Take Glyburide at the same time(s) each day in order to maintain a constant blood level.
		Glyburide must be used along with a proper diet and an exercise program.
	glyburide.canadapharmacydirect.com /glyburide_faq.php (288 words)

	NEJM -- A Comparison of Glyburide and Insulin in Women with Gestational Diabetes Mellitus
		glyburide or insulin according to an intensified treatment protocol.
		Glyburide Is Effective in Women with Gestational Diabetes.
		Ryan, E. Glyburide was as safe and effective as insulin in gestational diabetes.
	content.nejm.org /cgi/content/short/343/16/1134 (655 words)

	Importance of Early Insulin Secretion: Comparison of nateglinide and glyburide in previously diet-treated patients with ...
		glyburide, and placebo on postmeal glucose excursions and insulin
		the reduction induced by glyburide (from 5.15 to 4.63 mmol/l,
		glyburide, as was the incidence of events suggestive of hypoglycemia.
	care.diabetesjournals.org /cgi/content/full/24/6/983 (3377 words)

	The Sulfonylurea Glyburide Induces Impairment of Glucagon and Growth Hormone Responses During Mild Insulin-Induced ... (Site not responding. Last check: 2007-11-06)
		The Sulfonylurea Glyburide Induces Impairment of Glucagon and Growth Hormone Responses During Mild Insulin-Induced Hypoglycemia -- ter Braak et al.
		The Sulfonylurea Glyburide Induces Impairment of Glucagon and Growth Hormone Responses During Mild Insulin-Induced Hypoglycemia
		and glyburide at 60, 100, 140, and 180 min.
	care.diabetesjournals.org /cgi/content/full/25/1/107 (3101 words)

	Glynase (Glyburide, Micronase), NursingDiabetics.com, Your Total Diabetes Resource
		Glynase (glyburide, Micronase) description :rxlist:"Micronase Tablets (Standard Glyburide): Micronase tablets contain glyburide, which is an oral blood-glucose-lowering drug of the sulfonylurea class.
		What is the most important information I should know about Glynase (glyburide, Micronase) :ahealthyme.com:"Know the signs and symptoms of low blood sugar (hypoglycemia), which include headache, drowsiness, weakness, dizziness, fast heartbeat, sweating, tremor, and nausea.
		Glynase (glyburide, Micronase)uses and instructions :ElizJack@IntNet.Net:"This medication is used in the treatment of non-insulin dependent diabetes.
	www.nursingdiabetics.com /glynase.gliburide.micronase.html (1153 words)

	Sulfonylureas Inhibit Cytokine-Induced Eosinophil Survival and Activation -- Bankers-Fulbright et al. 160 (11): 5546 -- ...
		IL-5, IL-3, or GM-CSF in the presence of glyburide.
		Lidocaine, glyburide, and dexamethasone synergize to inhibit eosinophil survival and activation
		SUR for glyburide is much less than that of SUR1.
	www.jimmunol.org /cgi/content/full/160/11/5546 (4936 words)

	INHIBITORY EFFECT OF GLYBURIDE ON HUMAN CYTOCHROME P450 ISOFORMS IN HUMAN LIVER MICROSOMES -- Kim and Park 31 (9): 1090 ...
		glyburide is coadministered with agents that are cleared primarily
		glyburide was preincubated with the incubation medium at 37°C
		Glyburide was incubated using the conditions described under Materials and Methods.
	dmd.aspetjournals.org /cgi/content/full/31/9/1090 (1969 words)

	Glyburide - Resources from Educational and Academic Institutions (Site not responding. Last check: 2007-11-06)
		Diabetes Mellitus : The second generation agents glyburide and glipizide are more potent and may be attempted in patients with marked hyperglycemia or who failed the first...
		Micronized glyburide (Glynase PresTabÂ®), 3 mg, QD, 1.0-12 mg.
		White on glyburide 5 mg daily in addition to her metformin.
	drugs.mongabay.com /Glyburide.html (1309 words)

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