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Topic: Glycoside


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In the News (Tue 24 Nov 09)

  
  CAZy - Carbohydrate-Active enZYmes   (Site not responding. Last check: 2007-11-01)
The CAZy database describes the families of structurally-related catalytic and carbohydrate-binding modules (or functional domains) of enzymes that degrade, modify, or create glycosidic bonds.
Glycoside Hydrolases GlycosylTransferases Polysaccharide Lyases Carbohydrate Esterases Carbohydrate-Binding Modules
AFMB - CNRS - Universités Aix-Marseille I and II Please send your comments to :
afmb.cnrs-mrs.fr /CAZY/fam/acc_GH.html   (56 words)

  
  BioMed Central | Abstract | GH97 is a new family of glycoside hydrolases, which is related to the alpha-galactosidase ...
GH97 is a new family of glycoside hydrolases, which is related to the alpha-galactosidase superfamily
GH97 is a new family of glycoside hydrolases, which is related to the α-galactosidase superfamily
-barrel fold of the catalytic domain and a retaining mechanism of the glycoside bond hydrolysis.
www.biomedcentral.com /1471-2164/6/112/abstract   (302 words)

  
  Spartanburg SC | GoUpstate.com | Spartanburg Herald-Journal   (Site not responding. Last check: 2007-11-01)
Formally, a glycoside is any molecule in which a sugar group is bonded through its anomeric carbon to another group via an O-glycosidic bond or an S-glycosidic bond; glycosides involving the latter are also called thioglycosides.
Fischer glycosidation refers to the synthesis of glycosides by the reaction of unprotected monosaccharides with alcohols (usually as solvent) in the presence of a strong acid catalyst.
Cyanogenic glycosides can be found in the fruits (and wilting leaves) of the rose family (including cherries, apples, plums, almonds, peaches, apricots, rasberries, and crabapples).
www.goupstate.com /apps/pbcs.dll/section?category=NEWS&template=wiki&text=glycoside   (855 words)

  
 ARS | Publication request: Periderm Resin Glycoside Contents of Sweetpotato Clones and Their Biological Activity
Resin glycoside extracted from `Regal' periderm and included in potato dextrose agar culture medium were inhibitory to the growth of four fungus species that cause rotting of sweetpotatoes.
Insect damage ratings of the clones and their periderm resin glycosides content were negatively correlated, and all clones with higher glycoside contents exhibited moderate or low injury, and all clones with high injury ratings had low contents.
Resin glycosides extracted from `Regal' periderm and incorporated into potato dextrose agar medium were inhibitory to the growth of four fungus species that are pathogens of sweetpotato roots.
www.ars.usda.gov /research/publications/publications.htm?SEQ_NO_115=144501   (472 words)

  
 Pharmaceutical preparation comprising a cardiac glycoside with a polymer coating - Patent 4263273
The present invention is related to a novel pharmaceutical preparation comprising a digitalis glycoside or a similar compound effective in the treatment of cardiac disorders, and a process for producing such preparation, and a method of treatment using such preparation.
An object of the invention is to provide a pharmaceutical preparation in which a cardiac glycoside comprised therein is protected against substantial decomposition in the acid environment of the stomach of a mammal including man, without loss of bioavailability on release and intestinal absorbtion.
Digitalis glycosides or cardiac glycosides constitute a class of drugs among which are a few of the oldest drugs in current use.
www.freepatentsonline.com /4263273.html   (3179 words)

  
 Brainboost - glycoside   (Site not responding. Last check: 2007-11-01)
Formally, a glycoside is any molecule in which a sugar group is bonded through its anomeric carbon to another group via an O - glycosidic bond or an S - glycosidic bond ; glycosides involving the latter are also called thioglycosides.
Chemically, a glycoside is one or more sugar groups terminating in some sort of amide group.
Facts (generated by robot; please edit if you find it inaccurate) In chemistry, a glycoside is any molecule in which a sugar group is bonded through its anomeric carbon to another group via an O - glycosidic bond or an S - glycosidic bond; the latter are also called thioglycosides.
www.brainboost.com /search.asp?Q=glycoside&lfmq=1   (120 words)

  
 Acetals   (Site not responding. Last check: 2007-11-01)
To a solution of the glycoside and MEM-Cl (1.5 eq) in dry DCM, diisopropylethylamine (1.5 eq) is added and stirred at room temperature under an inert atmosphere until complete by TLC (usually 5 h).
The glycoside is dissolved in DCM and magnesium bromide etherate (excess) is added at room temperature under an inert atmosphere.
The glycoside is dissolved in EtOAc:Hex (1:2) and catalytic Pd(OH)
www.faculty.virginia.edu /mcgarveylab/Carbsyn/Acetals.html   (1614 words)

  
 eMedicine - Toxicity, Digitalis : Article Excerpt by: Donald Schreiber, MD, CM   (Site not responding. Last check: 2007-11-01)
The ancient Romans used red squill, a cardiac glycoside derived from the sea onion, as a diuretic and heart medicine.
Cardiac glycosides are found in certain flowering plants such as oleander and lily-of-the-valley.
Cardiac glycoside toxicity from plants, such as oleander, foxglove, and lily-of-the-valley, is uncommon but potentially lethal.
www.emedicine.com /emerg/byname/toxicity-digitalis.htm   (427 words)

  
 eMedicine - Plant Poisoning, Glycosides - Cardiac : Article Excerpt by: Raffi Kapitanyan, MD   (Site not responding. Last check: 2007-11-01)
Background: Cardiac glycosides are found in a diverse group of plants including Digitalis purpurea and Digitalis lanata (foxgloves), Nerium oleander (common oleander), Thevetia peruviana (yellow oleander), Convallaria majalis (lily of the valley), Urginea maritima and Urginea indica (squill), Strophanthus gratus (ouabain), Apocynum cannabimum (dogbane), and Cheiranthus cheiri (wallflower).
Toxicity from herbal cardiac glycosides was well recognized by 1785, when William Withering published his classic work describing therapeutic uses and toxicity of foxglove, D purpurea.
Therapeutic use of herbal cardiac glycosides continues to be a source of toxicity today.
www.emedicine.com /emerg/byname/plant-poisoning-glycosides---cardiac.htm   (556 words)

  
 UpToDate Digitalis (cardiac glycoside) intoxication
— Cardiac glycoside poisoning caused by digitalis or other compounds is a potentially life-threatening intoxication.
Cardiac glycoside toxicity can also result from ingestion of certain plants, including yellow oleander (Thevetia peruviana) and foxglove (Digitalis purpurea), and a similar toxidrome has been associated with use of herbal dietary supplements [5-9].
Cardiac glycoside toxicity can occur in a patient with any condition that either increases total body levels, or modifies cardiac sensitivity to the drug.
patients.uptodate.com /topic.asp?file=ad_tox/7096   (447 words)

  
 Dorlands Medical Dictionary   (Site not responding. Last check: 2007-11-01)
Cardiac glycosides increase the force of contraction of cardiac muscle and some are used as cardiotonics and antiarrhythmics.
The term is often used to denote any drug chemically and pharmacologically related to these glycosides, although not all are derived from Digitalis (e.g., ouabain); in this case it is equivalent to cardiac g.
(gli”ku-rōn´īd) a glycoside of a glycuronic (uronic) acid, often specifically a glucuronide.
www.mercksource.com /pp/us/cns/cns_hl_dorlands.jspzQzpgzEzzSzppdocszSzuszSzcommonzSzdorlandszSzdorlandzSzdmd_g_09zPzhtm   (2916 words)

  
 vgn-ext-hidden_PubMed   (Site not responding. Last check: 2007-11-01)
Cloning, expression, and characterization of a glycoside hydrolase family 50 beta-agarase from a marine Agarivorans isolate.
JT1070, indicating that it belongs to the family glycoside hydrolase (GH)-50.
The gene corresponding to a mature protein of 976 amino acids was inserted and expressed in Escherichia coli.
www.plwc.org /portal/site/ASCO/menuitem.a3fb42726842a82627c4c291ee37a01d/?vgnextoid=d70b3608f9958010VgnVCM100000f2730ad1RCRD&index=n&pmid=17028783   (221 words)

  
 Alkyl glycoside fatty acid polyester fat substitute food compositions and process to produce the same (US5550220)
A method for producing alkyl glycoside polyesters comprising admixing a lower acyl ester alkyl glycoside, a fatty acid lower alkyl ester, and an alkaline metal catalyst to form a reaction mixture.
Novel fat substitute food compositions containing alkyl glycoside fatty acid polyesters are produced in accordance with this present invention.
The alkyl moiety may be unsubstituted or substituted by from 1-3 free hydroxyl groups or fatty acid esterified hydroxyl groups.
www.delphion.com /details?pn=US05550220__   (899 words)

  
 DATA TO THE CARDIAC GLYCOSIDE CONTENT OF ADONIS VERNALIS L., IN HUNGARY
It was established that within a habitat the total glycoside content of both above ground shoots /CV = 32.38 %, x = 543.2 mg/100 g/ and root-stocks /CV = 40.39 %, x = 224.4 mg/100 g/ of plant individuals is also greatly variable.
There is a medium close correlation between the glycoside content of above and underground plant parts /r = 0.69/.
The frequency distribution of the total glycoside content of populations cannot be fitted to the curve of normal frequency distribution.
www.actahort.org /books/96/96_9.htm   (173 words)

  
 Surfynol Surfactants as Defoamers for Glyphosate Formulations with Alkyl Glycoside Surfactants
A major limitation to the use of alkyl glycosides as surfactants for liquid glyphosate formulations is their unacceptable degree of foaming when diluted in the spray tank.
I have found that certain acetylenic diol surfactants can be used as defoamers in glyphosate formulations with an alkyl glycoside.
The acetylenic diol surfactant was completely solubilized by the alkyl glycoside in the concentrated formulation.
www.astm.org /DIGITAL_LIBRARY/STP/PAGES/STP25120S.htm   (223 words)

  
 [No title]
O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety.
A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families [1, 2, 3].
Glycoside hydrolase family 57 GH_57 comprises enzymes with two known activities; alpha-amylase (EC:3.2.1.1) and 4-alpha-glucanotransferase (EC:2.4.1.-).
www.ebi.ac.uk /interpro/DisplayIproEntry?ac=IPR004300&format=curator   (251 words)

  
 Evidence that a New Antibiotic Flavone Glycoside Chemically Defends the Sea Grass Thalassia testudinum against ...
H NMR spectrum of this substance was indicative of a flavone glycoside,
the compound being quantified was the flavone glycoside.
C magnetic resonance spectra of aldoses and derived methyl glycosides.
aem.asm.org /cgi/content/full/64/4/1490   (5074 words)

  
 JIS: Tschinkel 2.12.2002
Cucurbitacins are feeding stimulants for diabroticite beetles, including corn rootworms and cucumber beetles, which can be added to a bait containing an insecticide thereby reducing the levels of other insecticide treatments needed to control these pests.
One of them, cucurbitacin E- glycoside, is water soluble and easily processed from mutant bitter Hawkesbury watermelons (BHW) that express elevated levels of cucurbitacin.
Storage of BHW extract at room temperature resulted in a 92% reduction of cucurbitacin E-glycoside over two months, while refrigeration or freezing resulted in a 60% loss of the active ingredient during this time.
www.insectscience.org /2.19   (4268 words)

  
 Drugs and Treatments - Questran Oral - Interactions Monograph from WebMD
When these two medicines are taken together, your body may not absorb your digitalis glycoside properly.
This may decrease the beneficial effects of your digitalis glycoside.
Your doctor may check your blood level of digitalis glycoside and adjust the dose of your medicine.
www.webmd.com /drugs/drug-3334-Questran+Oral.aspx?drugid=3334&drugname=Questran+Oral&dmid=76&dmtitle=CHOLESTYRAMINE%3b+COLESTIPOL%2fDIGITALIS+GLYCOSIDES%2c+ORAL&intrtype=DRUG&pagenumber=9   (462 words)

  
 sterols
Sterols may be found either as free sterols, acylated (sterol esters), alkylated (steryl alkyl ethers), sulfated (cholesterol sulfate), or linked to a glycoside moiety (steryl glycosides) which can be itself acylated (acylated sterol glycosides).
Based on their occurrence in sediments with a high diatom input, it was suggested that yet unknown diatoms should be a direct biological source.
In a plant (Edgeworthia chrysantha), it was demonstrated the presence of two steryl glycosides (sitosterol glucopyranoside acylated with linoleic or linolenic acid) which have piscicidal activities (at a concentration of 100 ppm they kill Oryzias latipes within about two hours) (Hashimoto T et al.
www.cyberlipid.org /sterols/ster0003.htm   (2319 words)

  
 Biochem. J. (2006) 400, 43-52 - E.S. Martens-Uzunova and others - Exo-acting pectinolytic glycoside hydrolases of A. ...
By applying bioinformatics tools, 12 new genes, putatively encoding family 28 glycoside hydrolases, were identified.
Seven of the newly discovered genes form a new gene group, which we show to encode exoacting pectinolytic glycoside hydrolases.
The results from the present study demonstrate that exo-acting glycoside hydrolases play a prominent role in pectin degradation.
www.biochemj.org /bj/400/bj4000043.htm   (374 words)

  
 Detection of poisoning by plant-origin cardiac glycoside with the Abbott TDx analyzer -- Cheung et al. 35 (2): 295 -- ...
Detection of poisoning by plant-origin cardiac glycoside with the Abbott TDx analyzer -- Cheung et al.
Detection of poisoning by plant-origin cardiac glycoside with the Abbott TDx analyzer
Cardiac glycoside poisoning caused by ingestion of plant material is common
www.clinchem.org /cgi/content/abstract/35/2/295   (313 words)

  
 Superior Protection against Malaria and Melanoma Metastases by a C-glycoside Analogue of the Natural Killer T Cell ...
glycosidic O by CH This alteration is expected to render the
Glycoside CH is nonpolar and hydrophobic; it repels hydrogen bond donors.
In contrast, glycoside oxygen is polar and the electron pairs can form hydrogen bonds with N–H and O–H donors.
www.jem.org /cgi/content/full/198/11/1631   (5045 words)

  
 Nature of the Schwann Cell Electrical Potential: Effects of the external ionic concentrations and a cardiac glycoside ...
Nature of the Schwann Cell Electrical Potential: Effects of the external ionic concentrations and a cardiac glycoside -- Villegas et al.
Effects of the external ionic concentrations and a cardiac glycoside
caused by the glycoside was followed by a gradual depolarization
www.jgp.org /cgi/content/abstract/51/1/47   (223 words)

  
 Red squill glycoside - toxicity, ecologicial toxicity and regulatory information
Chemical Identification and Use for Red squill glycoside
There may be other diseases and chemicals that have similar symptoms.
Sorry, no water quality standards or criteria have been established for this chemical by the U.S. or Canadian governments; however, there may be criteria established for related chemicals.
www.pesticideinfo.org /Detail_Chemical.jsp?Rec_Id=PC34318   (685 words)

  
 [No title]   (Site not responding. Last check: 2007-11-01)
Glycoside hydrolase family 28 GH_28 comprises enzymes with several known activities; polygalacturonase (EC:3.2.1.15); exo-polygalacturonase (EC:3.2.1.67); exo-polygalacturonase (EC:3.2.1.82); rhamnogalacturonase (EC not defined).
IPR000743 Glycoside hydrolase, family 28 61 - 378
IPR000743 Glycoside hydrolase, family 28 103 - 443
www.ebi.ac.uk /interpro/IEntry?ac=IPR000743&format=simple   (633 words)

  
 glycoside - OneLook Dictionary Search
Tip: Click on the first link on a line below to go directly to a page where "glycoside" is defined.
Glycoside : Drug Discovery and Development [home, info]
Phrases that include glycoside: digitalis glycoside, cyanogenetic glycoside, glycoside hydrolase
www.onelook.com /?w=glycoside   (185 words)

  
 Molecular modeling of family GH16 glycoside hydrolases: Potential roles for xyloglucan transglucosylases/hydrolases in ...
Molecular modeling of family GH16 glycoside hydrolases: Potential roles for xyloglucan transglucosylases/hydrolases in cell wall modification in the poaceae -- Strohmeier et al.
Articles by Strohmeier, M. Articles by Pleiss, J. Molecular modeling of family GH16 glycoside hydrolases: Potential roles for xyloglucan transglucosylases/hydrolases in cell wall modification in the poaceae
Family GH16 glycoside hydrolases can be assigned to five subgroups
www.proteinscience.org /cgi/content/abstract/13/12/3200   (364 words)

  
 iota -Carrageenases Constitute a Novel Family of Glycoside Hydrolases, Unrelated to That of kappa -Carrageenases -- ...
iota -Carrageenases Constitute a Novel Family of Glycoside Hydrolases, Unrelated to That of kappa -Carrageenases -- Barbeyron et al.
Articles by Barbeyron, T. Articles by Kloareg, B. -Carrageenases Constitute a Novel Family of Glycoside Hydrolases, Unrelated to That of
Cloning and biochemical characterization of the fucanase FcnA: definition of a novel glycoside hydrolase family specific for sulfated fucans
www.jbc.org /cgi/content/abstract/275/45/35499   (507 words)

  
 Glycoside Hydrolases and Glycosyltransferases. Families, Modules, and Implications for Genomics -- Henrissat and Davies ...
The yellow boxes represent the catalytic domain with the glycoside hydrolase family number indicated after GH.
Several chitin synthases bear an N-terminal myosin motor protein and this strongly suggests that chitin synthesis may be guided by association with cytoskeletal structures (Fujiwara et al., 1997
A classification system of the catalytic domains of glycoside hydrolases and transglycosylases into families based on amino
www.plantphysiol.org /cgi/content/full/124/4/1515   (2855 words)

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