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Topic: Gonadotropin-releasing hormone

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Gonadotropin-releasing hormone - Wikipedia, the free encyclopedia Gonadotropin-releasing hormone 1 (GNRH1 also called LHRH) is a peptide hormone responsible for the release of FSH and LH from the anterior pituitary. GNRH1 is considered a neurohormone, a hormone produced in a specific neural cell and released at its neural terminal. Thus, a single hormone, GNRH1, controls a complex process of follicular growth, ovulation, and corpus luteum maintenance in the female, and spermatogenesis in the male. en.wikipedia.org /wiki/Gonadotropin-releasing_hormone   (624 words)

hirsutism / hypertrichosis - gonadotrophin releasing hormone agonists for hirsutism Use of a gonadotropin-releasing hormone agonist in the evaluation of postmenopausal virilization due to ovarian hyperthecosis. hirsutism / hypertrichosis - gonadotrophin releasing hormone agonists for hirsutism Gonadotrophin-releasing hormone agonist therapy for hirsutism is as effective as high dose cyproterone acetate but results in a longer remission. www.keratin.com /ah/ah024.shtml   (707 words)

Gonadotropin-releasing hormone analogue - Wikipedia, the free encyclopedia A gonadotropin-releasing hormone analogue, also known as a GnRH analogue, (sometimes analog) is a synthetic peptide drug modeled after the human hypothalamic gonadotropin-releasing hormone (GnRH). A gonadotropin-releasing hormone agonist (GnRH agonist) is an analogue that activates the GnRH receptor resulting in increased secretion of FSH and LH. Initially it was thought that agonists would be able to be used as potent and prolonged stimulators of pituitary gonadotropin release, but it was soon recognized that agonists, after their initial stimulating action – termed a “flare” effect -, eventually caused a paradoxical and sustained drop in gonadotropin secretion. en.wikipedia.org /wiki/Gonadotropin-releasing_hormone_analog   (279 words)

Agripedia Gonadotropin Releasing Hormone Gonadotropin Releasing Hormone is a substance released by the hypothalamus which has a stimulating effect on the gonads through luteinizing hormone and follicle stimulating hormone. www.ca.uky.edu /agripedia/GLOSSARY/grh.htm   (33 words)

The Women's Health Site Within the gonadotropin-releasing hormone agonist/estradiol group, there was a 33.7% reduction (95% confidence interval, -64.4 to -3.0) in the headache index during the treatment phase when compared with the placebo run-in phase; no difference was seen between those phases within the gonadotropin-releasing hormone agonist/placebo group. Similar improvements were observed in the gonadotropin-releasing hormone agonist/estradiol group for all secondary outcome measures with the exception of headache frequency, which was unchanged between the groups. Conclusions: Minimization of hormonal fluctuations with gonadotropin-releasing hormone agonist therapy alone is inadequate to prevent headache in women who are premenopausal with migraine. www.thewomenshealthsite.org /article_display.jsp?ArticleID=253   (381 words)

Distribution of Lamprey Gonadotropin-Releasing Hormone in the Brain and Pituitary Gland of Larval, Metamorphic, and Adult Sea Lampreys, Petromyzon marinus Gonadotropin-releasing hormone was observed in the neurohypophysis and preoptic area of the brain of larval, metamorphic, juvenile, and prespawning adults. Lamprey gonadotropin-releasing hormone was demonstrated in the brains of larval, metamorphic, and adult sea lampreys, Petromyzon marinus, using an immunoperoxidase technique. Changes in immunoreactivity of these cells and fibres in the brain and neurohypophysis correlate well with increased concentrations of hormone in the brain during development and with the timing of presumed changes in activity of cells in the adenohypophysis during metamorphosis. www.sgnis.org /publicat/cjz48.htm   (280 words)

Hormones of the Hypothalamus Somatostatin is also secreted by cells in the pancreas and in the intestine where it inhibits the secretion of a variety of other hormones. In fact, replacement hormone therapy with these hormones does not work unless the replacements are also given in spurts. Its principal function in the hypothalamus is to inhibit the release of prolactin (PRL) from the anterior lobe of the pituitary. users.rcn.com /jkimball.ma.ultranet/BiologyPages/H/Hypothalamus.html   (403 words)

eMedicine - Luteinizing Hormone-Releasing Hormone Deficiency : Article by James N Anasti, MD Clark SJ, Hauffa BP, Rodens KP: Hormone ontogeny in the ovine fetus: XIX: The effect of a potent luteinizing hormone-releasing factor agonist on gonadotropin and testosterone release in the fetus and neonate. The released gonadotropins stimulate the gonads to produce steroid hormones and sperm or to release oocytes. The role of GnRH as a gonadotropin regulator during early fetal life is suggested by the lack of LH and FSH in the pituitary and serum of fetuses that are anencephalic, as well as in the capacity of GnRH to induce LH synthesis in pituitary cells from midtrimester fetuses. www.emedicine.com /MED/topic1342.htm   (10177 words)

Luteinizing and Follicle Stimulating Hormones Luteinizing hormone (LH) and follicle-stimulating hormone (FSH) are called gonadotropins because stimulate the gonads- in males, the testes, and in females, the ovaries. Numerous hormones influence GnRH secretion, and positive and negative control over GnRH and gonadotropin secretion is actually considerably more complex than depicted in the figure. As describef for thyroid-simulating hormone, LH and FSH are large glycoproteins composed of alpha and beta subunits. arbl.cvmbs.colostate.edu /hbooks/pathphys/endocrine/hypopit/lhfsh.html   (709 words)

Gonadotropin Releasing Hormone Gonadotropin Releasing Hormone (GnRH) comes from the hypothalamus and turns on the entire reproductive system by stimulating pituitary gonadotropes to make FSH and LH subunit gonadotropins. biochem.ncsu.edu /faculty/miller/gnrh.htm   (26 words)

Gonadotropin Releasing Hormone Receptor (GnRHR) antibodies from Research Diagnostics Inc Gonadotropin releasing decapeptide hormone is hte key mediator in the integration of the neural and endocrine systems. Background: Gonadotropin releasing hormone (GnRH), also known as luteinizing hormone releasing hormone (LHRH), is a key molecule in the regulation of reproduction in vertebrates. The generation of GnRH pulses is effected by numerous stimuli, such as neural, hormonal and environmental. www.researchd.com /miscabs/gnrhrab.htm   (597 words)

Gonadotropin-releasing hormone (GnRH) for infertility - [Medication] Gonadotropin-releasing hormone (GnRH) is produced by the hypothalamus. To a woman who is not ovulating because her hypothalamus is not stimulating hormones that trigger ovulation (hypothalamic amenorrhea). It stimulates the pituitary gland to produce luteinizing hormone (LH) and, to a lesser extent, follicle-stimulating hormone (FSH). www.peacehealth.org /kbase/topic/detail/drug/hw201696/detail.htm   (285 words)

Gonadotropin-Releasing Hormone Does Not Directly Stimulate Luteinizing Hormone Biosynthesis in Male African Catfish -- Rebers et al. 66 (6): 1604 -- Biology of Reproduction A pulsatile gonadotropin-releasing hormone stimulus is required to increase transcription of the gonadotropin subunit genes: evidence for differential regulation of transcription by pulse frequency in vivo. The dopaminergic inhibition of the gonadotropin-releasing hormone-induced gonadotropin release: an in vitro study with fragments and cell suspensions from pituitaries of the African catfish, Clarias gariepinus (Burchell). The effect of gonadotropin-releasing hormone on growth hormone and gonadotropin subunit gene expression in the pituitary of goldfish, Carassius auratus. www.biolreprod.org /cgi/content/full/66/6/1604   (5046 words)

CCNM - Faculty Profiles Cameron, C.B., Mackie, G.O. Powell, J.F.F., Lescheid, D.W., and Sherwood, N.M. Gonadotropin-releasing hormone in mulberry cells of Saccoglossus and Pytchodera (Hemichordata: Enteropneusta). Lescheid, D.W., Schreibman, M.P., Magliulo-Cepriano, L., Warby, C.M. and Sherwood, N.M. A novel form of gonadotropin-releasing hormone (GnRH) is present in the brain of platyfish and green swordtail (Genus, Xiphophorus). Lescheid, D.W., Teresawa, E., Abler, L.A., Urbanski, H.F., Warby, C.M., Millar, R.P and Sherwood, N.M. A second form of gonadotropin-releasing hormone with characteristics of chicken GnRH-II is present in the primate brain. www.ccnm.edu /profiles/bios/lescheid.html   (710 words)

NEJM -- Induction of puberty in men by long-term pulsatile administration of low-dose gonadotropin-releasing hormone Gonadotropin-Releasing Hormone Deficiency in the Human (Idiopathic Hypogonadotropic Hypogonadism and Kallmann's Syndrome): Pathophysiological and Genetic Considerations. Gonadotropin levels rose to normal adult ranges within one week of therapy and to supraphysiologic levels by 14 days. Men with idiopathic hypogonadotropic hypogonadism have an abnormality in gonadotropin release and do not undergo normal puberty. content.nejm.org /cgi/content/abstract/307/20/1237   (576 words)

EPA - Endocrine Biological Action of Gonadotropin-Releasing Hormone in Lampreys Theseinvestigations will include if gonadotropin- releasing hormone and analogs could beused to inhibit by sterilization or control reproduction in lampreys as a complementarymethod in maintaining numbers of lampreys in the Great Lakes. In addition, these studies may lead to the development ofgonadotropin-releasing hormone analogs which could be used for controllingreproduction in sea lampreys. Inmammals, many analogs (related compounds to gonadotropin-releasing hormone) havebeen made and used in research to test these proteins as conceptive andcontraceptive measures. www.epa.gov /endocrine/inventory/NSF-040.html   (310 words)

Gonadotropin-releasing hormone agonist (GnRH-a) therapy for endometriosis Gonadotropin-releasing hormone agonist (GnRH-a) therapy is widely used to shrink endometriosis implants, which relieves pain. This is thought to raise your hormone levels enough to benefit your bones, but not enough to encourage endometriosis growth. GnRH-a therapy decreases production of the hormone estrogen to the levels women have after menopause. www.webmd.com /hw/endometriosis/hw101914.asp   (857 words)

Combined Use of Growth Hormone and Gonadotropin-releasing Hormone Analogues in Precocious Puberty: Theoretic and Practical Considerations -- Walvoord and Pescovitz 104 (4): 1010 -- Pediatrics Saggese G, Pasquino AM, Bertelloni S, Effect of combined treatment with gonadotropin releasing hormone analogue and growth hormone in patients with central precocious puberty who had subnormal growth velocity and impaired height prognosis. Kamp GA, Manasco PK, Barnes KM, Low growth hormone levels are related to increased body mass index and do not reflect impaired growth in luteinizing hormone-releasing hormone agonist-treated children with precocious puberty. Tanaka T, Yoshizawa A, Tanae A, Hibi I, Skizume K Relationships between puberty and growth at adolescence in growth-hormone-deficient males: effect of growth hormone and of associated gonadal suppression therapy. pediatrics.aappublications.org /cgi/content/full/104/4/S1/1010   (3893 words)

Directory of open access journals Luteinizing hormone secretion is regulated both by alterations in gonadotrope responsiveness to hypothalamic gonadotropin releasing hormone and by alterations in gonadotropin releasing hormone secretion. Previously, we reported that gonadotropin releasing hormone-stimulated second messenger inositol trisphosphate production was inhibited when RGS3 and gonadotropin releasing hormone receptor cDNAs were co-transfected into the COS cell line. RGS3 inhibits gonadotropin releasing hormone-stimulated second messenger production (inositol trisphosphate) as well as luteinizing hormone secretion from rat pituitary gonadotropes apparently by binding and suppressing the transduction properties of Gqα protein function. www.doaj.org /abstract?id=80628&toc=y   (285 words)

Medicinsk behandling af barnløshed Dette hormon får hypofysen til at udskille to gonadotropin-hormoner, kaldet Follicle Stimulationg Hormone (FSH) og Lutenising Hormone (LH). Disse hormoner er ansvarlige for modning af follikler i æggestokkene og ægløsningen. Hvis niveauet af prolaktin nedsættes stimuleres produktionen af gonadotropiner i hypofysen og dermed modning af follikler. www.netdoktor.dk /skema/barnloshed.htm   (609 words)

Gonadotropin-releasing hormone and its receptor in normal and malignant cells -- Harrison et al. 11 (4): 725 -- Endocrine-Related Cancer Gonadotropin-releasing hormone and its receptor in normal and malignant cells -- Harrison et al. Gonadotropin-releasing hormone and its receptor in normal and malignant cells and subsequent gonadotropin release is active in the early neonate, erc.endocrinology-journals.org /cgi/content/full/11/4/725   (7446 words)

News - Gonadotropin Releasing Hormone Agonist, Antagonist Show Similar Efficacy In Ovarian Stimulation: Presented at ASRM SAN ANTONIO, TX -- October 16, 2003 -- Infertile women who are treated with controlled ovarian stimulation with a gonadotropin releasing hormone (GnRH) antagonist have equivalent rates of embryo and clinical pregnancy compared with women who have stimulation with a GnRH agonist, according to a study from two large Mexican fertility clinics. Gonadotropin Releasing Hormone Agonist, Antagonist Show Similar Efficacy In Ovarian Stimulation: Presented at ASRM News - Gonadotropin Releasing Hormone Agonist, Antagonist Show Similar Efficacy In Ovarian Stimulation: Presented at ASRM www.docguide.com /news/content.nsf/news/8525697700573E1885256DC10058CAC5   (414 words)

gonadotropin-releasing hormone Cancer.gov Gonadotropin-releasing hormone agonists for hormone-refractory prostate cancer; Hormone replacement therapy; Oral contraceptives; Megestrol for anorexia/cachexia. His theory is that seizures may interfere with gonadotropin-releasing hormone, a chemical messenger made in the brain that starts a chain of events that ends... GnIH has the opposite effect of the hormone gonadotropin releasing hormone (GnRH), a neuropeptide that influences neural activity, which is released from the... www.cancer-help.org /cancer/0604/gonadotropin-releasing_hormone.html   (1087 words)

B WILLIAMS et al.: Oestradiol, cell cycle and GnRH signalling (Journal of Endocrinology) Stojilkovic SS, Stojilkovic SS and Catt KJ 1995 Expression and signal-transduction pathways of gonadotropin-releasing hormone receptors. Ramey JW, Ramey JW, Highsmith RF, Wilfinger WW and Baldwin DM 1987 The effects of gonadotropin-releasing hormone and estradiol on luteinizing hormone biosynthesis in cultured rat anterior pituitary cells. McArdle CA, McArdle CA and Poch A 1992 Dependence of gonadotrophin-releasing hormone release upon intracellular Ca pools is revealed by desensitization and by thapsigargin blockade. journals.endocrinology.org /joe/164/0031/joe1640031.htm   (1171 words)

Scientific Reports Jones, P.B.C. and Hsueh, A.J.W., "Regulation of Ovarian 20α-Hydroxysteroid Dehydrogenase by Gonadotropin Releasing Hormone and its Antagonist Hsueh, A.J.W. and Jones, P.B.C., "Regulation of Ovarian Granulosa and Luteal Function by Gonadotropin Releasing Hormone and Its Antagonist," in Jones, P.B.C., Conn, P.M., Marian, J. and Hsueh, A.J.W., "Binding of Gonadotropin Releasing Hormone Agonist to Rat Ovarian Granulosa Cells," www.nasw.org /users/Phill/reports.htm   (790 words)

Habibi page : HAMID R. HABIBI The effect of gonadotropin-releasing hormone on growth hormone and gonadotropin subunit gene expression in the pituitary of goldfish, carassius auratus. Pati D. and Habibi HR (2002) The involvement of protein kinase c and arachidonic acid pathways in the gonadotropin-releasing hormone regulation of oocyte meiosis and follicular steroidogenesis in the goldfish ovary. Murthy, C.K., Wong, A.O.L., Habibi, H.R., Rivier, J.E., Peter, R.E. (1994) Receptor binding of gonadotropin-releasing hormone (GnRH) antagonists that inhibit gonadotropin-II and growth hormone release in goldfish, Carassius auratus. www.acs.ucalgary.ca /%7Ehabibi/publication.html   (1426 words)

Gonadotropin-Releasing Hormone and Gonadotropin-Releasing Hormone Receptor Messenger Ribonucleic Acids Expression in Nontumorous and Neoplastic Pituitaries -- Sanno et al. 82 (6): 1974 -- Journal of Clinical Endocrinology & Metabolism 1989 Gonadotropin release by clinically nonfunctioning and gonadotroph pituitary adenomas in vivo and in vitro: relation to sex and effects of thyrotropin-releasing hormone, gonadotropin-releasing hormone and bromocriptine. 1983 Gonadotropin and alpha subunit secretion by human functionless pituitary adenomas in cell culture: long term effects of luteinizing hormone releasing hormone and thyrotropin releasing hormone. 1981 Studies of immunoreactive gonadotropin releasing hormone (GnRH) in rat anterior pituitary. jcem.endojournals.org /cgi/content/full/82/6/1974   (5251 words)

ExactAntigen gnrhr -- reagents, researchers, and patents (2002) Regulation of the gonadotropin-releasing hormone receptor (GnRHR) by RGS proteins: role of the GnRHR carboxyl-terminus Mol Cell Endocrinol 191:149-56. (2003) Dominant-negative action of disease-causing gonadotropin-releasing hormone receptor (GnRHR) mutants: a trait that potentially coevolved with decreased plasma membrane expression of GnRHR in humans J Clin Endocrinol Metab 88:3360-7. 1: EP 1496364 2005 Cloning and expression of gonadotropin-releasing hormone receptor www.exactantigen.com /gene/gag/gnrhr.html   (507 words)

Multimodal Influence of Estrogen upon Gonadotropin-Releasing Hormone Neurons -- Herbison 19 (3): 302 -- Endocrine Reviews of estradiol on GnRH release in the median eminence/mediobasal release (19, 20), was shown recently to be unaffected by estrogen NPY stimulates GnRH release from the median eminence, and this edrv.endojournals.org /cgi/content/full/19/3/302   (11348 words)

Gonadotropin-releasing hormone analogue (GnRH-a) therapy Gonadotropin-releasing hormone analogue (GnRH-a) therapy is approved for the treatment of endometriosis and uterine fibroids. Efficacy of pre-operative gonadotropin hormone releasing analogues for women with uterine fibroids undergoing hysterectomy or myomectomy: A systematic review. Add-back therapy and gonadotropin-releasing hormone agonists in the treatment of patients with endometriosis: Can a consensus be reached? my.webmd.com /hw/health_guide_atoz/aa76766.asp   (1086 words)

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