Where results make sense

About us   |   Why use us?   |   Reviews   |   PR   |   Contact us

Topic: Grading (tumors)

    Note: these results are not from the primary (high quality) database.

Salivary Gland Cancer Salivary gland tumors pose a particular challenge to the surgical pathologist primarily because of the complexity of the classification and the rarity of several entities, which may exhibit a broad spectrum of morphologic diversity in individual lesions, thus making differentiating benign from malignant tumors difficult. Histologic grading of salivary gland carcinomas is important in determining the proper treatment approach, although it is not an independent indicator of the clinical course and must be considered in the context of the clinical stage. Tumors of the salivary glands comprise those in the major glands (parotid, submandibular, and sublingual) and the minor glands (oral mucosa, palate, uvula, floor of mouth, posterior tongue, retromolar area and peritonsillar area, pharynx, larynx, and paranasal sinuses). www.meb.uni-bonn.de /cancer.gov/CDR0000062920.html

National Cancer Institute - Dictionary of Cancer Terms The objective of a grading system is to provide information about the probable growth rate of the tumor and its tendency to spread. A general term for tumors of the central nervous system, including astrocytomas, ependymal tumors, glioblastoma multiforme, and primitive neuroectodermal tumors. Grading systems are different for each type of cancer. www.cancer.gov /dictionary/db_alpha.aspx?expand=g   (3643 words)

eMedicine - Oligodendroglioma : Article by Subramanian Hariharan, MD Different grading systems are available for malignant tumors, but most pathologists use a simple two-tier grading system, diagnosing as "oligodendroglioma" tumors without anaplastic features and as "anaplastic oligodendroglioma" if several of the malignant features are present. Patients with anaplastic oligodendrogliomas who have loss of heterozygosity (LOH) on 1p or combined LOH on 1p and 19q survive substantially longer (mean, 10 y) than patients whose tumors lack these genetic changes (mean, 2 y). Although differences of opinion exist regarding the efficacy of radiotherapy for oligodendrogliomas, radiation is used routinely at diagnosis in patients who have undergone incomplete removal of nonanaplastic oligodendrogliomas and generally is recommended for patients with anaplastic oligodendrogliomas regardless of the extent of resection. www.emedicine.com /NEURO/topic281.htm   (3643 words)

Flat-Coated Retriever Society of America, Inc. Diagnosis of mast cell tumors can be made by examination of a fine needle aspiration, but excisional biopsy is essential if accurate histologic grading is desired. Mast cell tumors have not been shown to be genetically transmitted. Mast cell tumors are the most common malignant skin tumor in the dog. clubs.akc.org /fcra/healthmanual/mast.html   (3643 words)

National Cancer Institute - Tumor Grade: Questions and Answers However, the importance of tumor grade in planning treatment and estimating a patient’s prognosis is greater for certain types of cancers, such as soft tissue sarcoma, primary brain tumors, lymphomas, and breast and prostate cancer. Other grading systems include the Bloom-Richardson system for breast cancer and the Fuhrman system for kidney cancer. Grading systems are different for each type of cancer. www.cancer.gov /cancertopics/factsheet/Detection/tumor-grade   (780 words)

Mast Cell Disease in Dogs and Cats: An Overview Tumor location- The location of cutaneous mast cell tumors around mucocutaneous junctions is associated with a poorer prognosis. Mast cell neoplasms are usually solitary lesions, but multiple cutaneous tumors also occur. Traditionally, this process has involved clinical staging of disease, cytologic evaluation, and histologic grading of the neoplasms. www.vet.uga.edu /vpp/CLERK/Dahm   (780 words)

Flat-Coated Retriever Society of America, Inc. Diagnosis of mast cell tumors can be made by examination of a fine needle aspiration, but excisional biopsy is essential if accurate histologic grading is desired. Mast cell tumors have not been shown to be genetically transmitted. Mast cell tumors are the most common malignant skin tumor in the dog. clubs.akc.org /fcra/healthmanual/mast.html   (788 words)

National Cancer Institute - Dictionary of Cancer Terms The objective of a grading system is to provide information about the probable growth rate of the tumor and its tendency to spread. The systems used to grade tumors vary with each type of cancer. Grading systems are different for each type of cancer. www.cancer.gov /dictionary/db_alpha.aspx?expand=g   (3643 words)

Spitz Nevus Spitz tumors in children: a grading system for risk stratification. Spitz's nevi are acquired benign melanocytic skin tumors. The T1796A mutation of the BRAF gene is absent in Spitz nevi www.thedoctorsdoctor.com /diseases/spitz_nevus.htm   (12925 words)

OVARIAN CANCER: Prognosis At present, grading of ovarian carcinoma is clinically important only for stage I patients because chemotherapy is withheld for low grade tumors in view of their outstanding prognosis when untreated. Stage I patients with grade I tumors have a 5-year survival of over 90%, as do patients in stages IA and IB. FIGO stage is so powerful a predictor of prognosis in ovarian cancer that most other putative prognostic factors are of little importance in comparison to stage. ovariancancer.jhmi.edu /prognosis.cfm   (668 words)

USCAP 2003 Annual Meeting We have introduced a grading protocol that may be utilized to assess atypical Spitz tumors in children and adolescents for their metastatic potential. Metastatic melanoma may not only mimic primary melanoma but also various types of melanocytic nevi including banal compound and dermal nevi, atypical ("dysplastic") nevi, blue nevi (see above), pigmented spindle cell nevi, and Spitz tumors. In this author's experience mitoses are often few in number or absent in the dermal component. www.uscap.org /site~/92nd/companion01h2.htm   (2403 words)

Mucoepidermoid Carcinoma of the Salivary Glands: Clinicopathologic Review of 108 Patients Treated at the National Cancer Institute of Milan -- Guzzo et al. 9 (7): 688 -- Annals of Surgical Oncology Vascular invasion was found in 20% (10 cases) of the MISG tumors; Moreover, grading seems to be associated with a cases in MISG were categorized as high-grade tumors. www.annalssurgicaloncology.org /cgi/content/full/9/7/688   (2403 words)

[Brainlife] TORP SH (2002) - Diagnostic and prognostic role of Ki67 immunostaining in human astrocytomas using four different antibodies Astrocytomas have an inherent tendency to progress, and histopathological examination and grading do not always identify these subsets of tumors. For the entire tumor material, the use of median values as cutoff divided the astrocytomas into 2 groups: those tumors with the higher Ki67 PIs had significantly poorer prognosis than those with lower indices. Forty-one cerebral astrocytomas, graded according to the latest criteria of the World Health Organization, were included in the study: 22 diffuse fibrillary astrocytomas, 10 anaplastic astrocytomas and 9 glioblastomas. www.brainlife.org /abstract/torp_2002.htm   (287 words)

Kidney Cancer - Renal Cell Carcinoma (RCC) Therefore, grading of tumor cells is an important factor in assessing prognosis except in papillary RCC type where grading seems to have a minimal prognostic value. Recent data suggest that clear cell RCC has a slightly worse prognosis as compared to papillary or chromophobe cell RCC, however, the majority of low stage tumors, regardless of its cell type, can be cured with surgical resection. RCC is difficult to treat and rarely cured once it has spread beyond the kidney and current therapies have limited efficacy. www.cornellurology.com /uro/cornell/kidney/gi/rcc.shtml   (1227 words)

eMedicine - Gastrointestinal Stromal Tumors - Leiomyoma/Leiomyosarcoma : Article by Vu Nguyen, MD Given the potential malignant behavior of benign appearing GISTs, at least 1 group believes that all GISTs should be classified as malignant tumors on a low-to-high grading scale rather than on a benign-versus-malignant basis (Pierie, 2001). The tumors appear as hypoechoic masses that are contiguous with the fourth hypoechoic layer of the GI wall, which corresponds to the muscularis propria. Previously, these tumors were classified as GI leiomyomas, leiomyosarcomas, leiomyoblastomas, or schwannomas as a result of their histologic findings and apparent origin in the muscularis propria layer of the intestinal wall. www.emedicine.com /radio/topic388.htm   (3781 words)

Grade - Wikipedia, the free encyclopedia in pathology, grading (tumors) is a measure of the aggressiveness of a tumor, using either a numeric grade ("Grade 2") or a descriptive grade ("high grade"). Grade is a Hardcore punk rock band of the Emo genre. In Phylogenetics an (evolutionary) grade is a paraphyletic group of organisms. en.wikipedia.org /wiki/Grade   (388 words)

p27 Labeling Index and Proliferation in Gastrointestinal Stromal Tumors: Correlations with Clinicopathologic Factors and Recurrence -- Gelen et al. 33 (7): 346 -- Japanese Journal of Clinical Oncology A comparison of proliferating cell nuclear antigen (PCNA) immunostaining, nucleolar organizing region (AgNOR) staining, and histological grading in gastrointestinal stromal tumors. 24 Sbaschnig RJ, Cunningham RE, Sobin LH, O’Leary TJ. 30 Ito Y, Takeda T, Sasaki Y, Sakon M, Yamada T, Ishiguro S, et al. jjco.oxfordjournals.org /cgi/content/full/33/7/346   (388 words)

Neoplasia I Lab Answers, No Images Grading cancers = attempts to predict the clinical behavior of malignant tumors and to establish criteria for therapy. Benign Nuclear Features: rare or no mitoses which are normal; nuclei of tumor cells resemble surrounding myometrium with no pleomorphism, no hyperchromasia, and normal nucleoli. Features are histologic/cytologic including assessment of anaplasia (presence or lack of differentiated features), and assessment for the rapidity of growth and the degree of abnormality of growth (number of mitoses, abnormal mitoses, pleomorphism) All these features would be present in this tumor in some regions. medic.med.uth.tmc.edu /edprog/Path/Neo1/NeoQA.htm   (1838 words)

Sudhoffs Archiv Reviewing the literature back to the first available publications, five phases in the development of the grading systems for malignant soft tissue tumors could be distinguished: 1845—1919: phase of identification, 1927—1964: phase of description, 1965—1977: phase of predominant mitotic activity, 1979—1983: phase of predominant tumor type, from 1984: phase of multifactorial systems. Im Jahr 316 hat dann der Bologneser Arzt und Anatom Mundinus Liucius (Mondino de’ Liuzzi) seine — zunächst noch handschriftliche — ‘Anothomia Mondini’ veröffentlicht, mit der er die erste Beschreibung einer systematischen Zergliederung der Menschenleiche seit der Zeit der Ptolemäer vorlegte. Entgegen einem Hauptargument des bahnbrechenden russischen Mediävisten Aron Gurevich kann somit festgestellt werden, daß antike Traditionen nicht nur unter gebildeten Eliteschichten weitertradiert und bekannt waren, sondern unter viel breiteren Volksschichten das Leben, den Glauben und die Alltagspraxis beeinflußten. www.steiner-verlag.de /Sudhoff/Sudhoff6.html   (1838 words)

Leiomyosarcoma Leiomyosarcomas of soft tissues are an aggressive group of tumors with a high incidence of recurrence. It has been difficult to predict the clinical behavior of leiomyosarcomas using the morphology-based grading system, even though tumor size and histological grade have correlated with biologic behavior in some studies. One of the lesions arose in the stomach, one in the ileum, and 2 in the colon. www.thedoctorsdoctor.com:16080 /diseases/leiomyosarcoma.htm   (4869 words)

CancerLIT: 705036 Local resection in T1-Tumors with G1- or G2-Grading may produce comparable results. While intestinal reconstruction may improve the quality of life in R0 resected patients we reluctantly perform this in noncurative treated patients, since their expected survival time is limited and reconstructive surgery in these pretreated patients (radiation and surgery) increases the risk of morbidity. The identical operative risk and identical survival rates justify the application of multivisceral resection in the treatment of colorectal carcinoma. cancerweb.ncl.ac.uk /cancernet/cancerlit/705036.html   (7385 words)

Tampere University: Dissertation information The assignment pf astrocytoma malignancy grade on the basis of the established histopathological grading criteria may vary considerably between neuropathologists. the present study demonstrates that telomerase could be activated during the early stages of the tumorigenesis of astrocytomas, as in grade 2 tumors. The activation of telomerase may have a signficant role in sustaining the proliferation capacity of astrocytoma cells. acta.uta.fi /english/teos.phtml?3094   (290 words)

Cell cycle kinetics and DNA ploidy in head and neck squamous cell cancer (HNSCC) (Meeting abstract). DNA ploidy and BUDR-LI were not significantly correlated with tumor site, clinical stage or pathological grading but DNA-aneuploid tumors showed shorter Tpot (4.1 days) than DNA-diploid ones (8 days; p less than 0.05). Cell cycle kinetics and DNA ploidy may add prognostic information in HNSCC and provide a rationale for improving the results of radio (RT) or chemotherapy (CT). Cell cycle kinetics and DNA ploidy in head and neck squamous cell cancer (HNSCC) (Meeting abstract). www.aegis.com /aidsline/1995/dec/M95C3231.html   (446 words)

The new WHO Classification of Tumors affecting the Central Nervous System A number of grading systems are in common use for tumors of astrocytic lineage (i.e. The new WHO system is particularly useful in this regard with only a few notable exceptions (for example all or almost all gemistocytic astrocytomas are actually anaplastic and hence grade III or even IV rather than grade II as designated by the WHO system). In 1993 the WHO ratified a new comprehensive classification of neoplasms affecting the central nervous system. neurosurgery.mgh.harvard.edu /newwhobt.htm   (894 words)

Mast Cell Disease in Dogs and Cats: An Overview Traditionally, this process has involved clinical staging of disease, cytologic evaluation, and histologic grading of the neoplasms. Tumor recurrence and systemic signs of disease are associated with more aggressive mast cell tumors and poorer clinical prognosis. Mast cell is present in the blood smear of a dog with cutaneous neoplasms. www.vet.uga.edu /vpp/CLERK/Dahm   (1829 words)

Grading of Tumors and Tumorlike Lesions of Bone: Evaluation by FDG PET -- Schulte et al. 41 (10): 1695 -- The Journal of Nuclear Medicine Grading of Tumors and Tumorlike Lesions of Bone: Evaluation by FDG PET -- Schulte et al. 41 (10): 1695 -- The Journal of Nuclear Medicine jnm.snmjournals.org /cgi/content/abstract/41/10/1695   (1829 words)

Acoustic Neuromas In cases of large tumors with a thinned out nerve that is splayed over the surface of the tumor, the nerve is physically saved during surgery, but it may not function well or only partially recover. Therefore, a grading system has been devised to allow both physicians and patients to tailor their expectations for outcome accordingly. Immediately associated with these nerves is the 7th cranial nerve, the nerve that controls the muscles of the face, salivation, tearing, and taste. www.brain-surgery.com /acoustic.html   (1829 words)

Kidney (Renal Cell) Cancer - October 2001: 710440 A prospective randomized study was conducted to examine the significance of prophylactic intravesical instillation of mitomycin C (MMC) and cytosine arabinoside (Ara-C) to prevent recurrent bladder tumors after surgery for superficial transitional cell carcinoma of the upper urinary tract. AB - The authors attempted to determine the potential prognostic value of several ultrastructural morphometric parameters, including nuclear, nucleolar, and cytoplasmic features, that could be used in the objective and reproducible histological grading of clear cell renal cell carcinoma. We performed a genomewide scan in one large kindred with BHD and, by linkage analysis, localized the gene locus to the pericentromeric region of chromosome 17p, with a LOD score of 4.98 at D17S740 (recombination fraction 0). www.acor.org /cnet/710440.html   (1829 words)

The new WHO Classification of Tumors affecting the Central Nervous System The proportion of tumors with mutations characteristic of less anaplastic tumors remains constant as anaplasticity increases. The WHO classification also provides a parallel grading system for each type of tumor. Anaplastic astrocytomas (grade 3)-whether found in preexistent low grade astrocytomas or detected de novo -have a similar incidence of p53 mutations but, in addition, show a loss of heterozygosity on chromosome 19q in more than 40% of cases. neurosurgery.mgh.harvard.edu /newwhobt.htm   (1829 words)

Try your search on: Qwika (all wikis)

About us   |   Why use us?   |   Reviews   |   Press   |   Contact us   Copyright © 2005-2007 www.factbites.com Usage implies agreement with terms.