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Topic: Granulation tissue

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	Granulation tissue - Wikipedia, the free encyclopedia
		Granulation tissue is the perfused, fibrous connective tissue that replaces a fibrin clot in healing wounds.
		Granulation tissue typically grows from the base of a wound and is able to fill wounds of almost any size.
		Fibroblasts, the main cells that deposit granulation tissue, depend on oxygen to proliferate and lay down the new extracellular matrix.
	en.wikipedia.org /wiki/Granulation_tissue (320 words)

	Show Articles (Site not responding. Last check: 2007-10-11)
		Granulation tissue is the pebbly or granular appearing tissue which develops in healing wounds anywhere on the horse's body.
		Granulation tissue forms primarily in wounds left open to heal, rather than those wounds that are primarily closed (sutured).
		Following surgical treatment of moderate to large granulating large wounds, a splint or a cast might be necessary to prevent the granulation tissue from regrowing and to enable the skin edges to advance and cover the wound.
	www.xcodesign.com /aaep/displayArticles.cfm?ID=160 (896 words)

	bronchiolitis obliterans (Site not responding. Last check: 2007-10-11)
		This granulation tissue polyp is a very non-specific histologic finding as it is seen in most infectious pneumonias, diffuse alveolar damage, aspiration, usual interstitial pneumonia, cryptogenic organizing pneumonia, among other conditions.
		Over time this myxoid tissue is re-epithelialized through the growth of the adjacent metaplastic epithelium which incorporates the loose granulation tissue into the wall of the airway.
		It is important to recognize that this granulation tissue reaction is part of the acute lung injury associated with the acute rejection reaction, rather than bronchiolitis obliterans.
	tpis.upmc.edu /tpis/lung/bron02.html (2312 words)

	Continuous passive motion (CPM): Theory and principles of clinical application (Site not responding. Last check: 2007-10-11)
		Granulation tissue is a highly vascularized, loosely organized tissue with material properties somewhere between a highly organized blood clot and loose areolar fibrous tissue.
		As this granulation tissue appears within and surrounding the joint, the stiffness previously due to fluid accumulation becomes increasingly due to the deposition of a solid extracellular matrix.
		In this third stage of granulation tissue deposition, extracellular matrix is being deposited in the tissues around the knee joint, causing them to thicken and greatly lose their compliance.
	www.vard.org /jour/00/37/2/odriscoll.htm (5788 words)

	Granulation tissue (Site not responding. Last check: 2007-10-11)
		Granulation tissue is the tissue that replaces a fibrin clot in healing tissue.
		This is necessary because not only is this tissue vulnerable due to the healing process, but also because (not being fully repaired) it often does not have an effective, intact barrier of skin to provide a first line of defence from invading pathogens.
		Vascularisation: It is necessary for a network of blood vessels to be established as soon as possible to provide the growing tissue with nutrients, and to take away cellular wastes, as well as transporting new leukocytes to the area.
	www.mrsci.com /Anatomical-Pathology/Granulation_tissue.php (237 words)

	eMedicine - Scalp Reconstruction : Article by Basil S Cherpelis, MD (Site not responding. Last check: 2007-10-11)
		Granulation is a predictable method of wound healing if the wound is cared for properly, and granulation is not as dependent on vascular pedicles or vascular ingrowths as flaps and grafts.
		Granulation can be used to heal large wounds as long as wound care is meticulously performed and the patient and physician have patience.
		Two additional techniques, porcine xenograft–assisted granulation and purse-string suture–assisted granulation, may be used in a patient who cannot care for the wound but who is otherwise a good candidate for granulation (eg, an elderly patient who lives alone and a patient who is unable to see or reach his or her scalp).
	www.emedicine.com /derm/topic906.htm (10443 words)

	Wound healing
		Organisation is when the inflammatory exudate is replaced by granulation tissue and fibrous repair is when the granulation tissue is then replaced by fibrous scar tissue.
		Myofibroblasts contract when the granulation tissue forms and this reduces the surface area of the open wound to 10% of its original size.
		The molecular type of collagen secreted early on in granulation tissue formation is type III, which is later replaced by degradation and secretion of type I collagen.
	members.tripod.com /Alkam/seencas3.html (896 words)

	[No title] (Site not responding. Last check: 2007-10-11)
		When the oral mucosa is injured repeatedly, excessive amounts of granulation tissue may be produced in the lamina propria of the oral mucous membrane.
		While the lesions to be described next probably started out being composed of granulation tissue, their persistence is accompanied with decreased vascularity and cellularity and increased fibroblastic activity and collagen deposition, a change reminiscent of scar formation in wound repair.
		The tissue lining the fissure part of the lesion is generally more vascular (more blood vessels) and, as mentioned, the epithelium lining the fissure bottom is generally ulcerated with inflammation of the connective tissue underlying it.
	www.usc.edu /hsc/dental/opath/Chapters/Chapter16_Text.html (3854 words)

	ISPD
		In all exits the drainage increased and became purulent, and granulation tissue became soft or fleshy.
		Instead, drainage became purulent, the sinus lining became composed of granulation tissue at week 1 or 2, and the tissue became slightly or frankly exuberant.
		Nonionic surfactant that cleanses the exit and is not harmful to the granulation tissue seems to be preferable to strong disinfectants.
	www.ispd.org /guidelines/articles/twardowski/page14.php3 (2581 words)

	Wound Ostomy Continence Nurse Society OASIS Guidance
		Fully Granulating: Wound bed filled with granulation tissue to the level of the surrounding skin or new epithelium; no dead space, no avascular tissue; no signs or symptoms of infection; wound edges are open.
		Early/Partial Granulation: > 25% of the wound bed is covered with granulation tissue; there is minimal avascular tissue (i.e., <25% of the wound bed is covered with avascular tissue); may have dead space; no signs or symptoms of infection; wound edges are open.
		Granulation Tissue: The pink/red, moist tissue comprised of new blood vessels, connective tissue, fibroblasts, and inflammatory cells, which fills an open wound when it starts to heal; typically appears deep pink or red with an irregular, "berry-like" surface.
	www.dhfs.state.wi.us /rl_dsl/HHAs/HHAs01-036b.htm (1396 words)

	MuscSktf7-Osteomyelitis_Text_pv
		This soft tissue is of intermediate signal on the T1 Weighted images and appears hyperintense on the T2 Weighted images and is noted around the distal half of the left tibia.
		The marrow cavity is replaced by granulation tissue and later by fibrous tissue.
		Soft tissue edema and infection of the fasciae, muscles, and subcutaneous tissues cannot be differentiated on T1W, T2W and fat-suppressed sequences.
	www.mribhatia.com /muscktf7/muscsktf7_text_pv.html (2889 words)

	Infectious Diseases in Children: New Advances in Topical Treatment of the Draining Ear
		The middle ear mucosa may become inflamed with an indwelling tube and granulation tissue grows through the lumen of the tympanostomy tube into the external canal and surrounds the tube.
		The second manner in which granulation forms is from a tube that has extruded and is either sitting on the tympanic membrane or in the ear canal.
		By bathing the granulation tissue in an appropriate topical agent, the infectious and inflammatory response is well managed.
	idinchildren.com /monograph/0309/pransky2.asp (1395 words)

	Exuberant protuberant
		Granulation tissue fills in a large wound so that epithelial cells can grow across the surface of the wound and allow the skin to recover the area.
		Granulation tissue is resistant to infection, so it protects dangerous wounds from bacterial damage.
		Studies have shown that a bandage reduces formation of granulation tissue and increases the amount of carbon dioxide near the wound's surface.
	www.horses-and-horse-information.com /articles/0799fles.shtml (965 words)

	Defective Angiogenesis in the Inflammatory Granulation Tissue in Histidine Decarboxylase-deficient Mice but not in Mast ...
		in the angiogenesis of the cotton thread-induced granulation
		mice were killed and a piece of the tissue, 2 cm in diameter surrounding the implanted cotton thread including the skin, cutaneous muscle layer, subcutaneous tissues, the granulation tissue together with the cotton thread, was dissected 0, 1, 3, and 5 d after cotton thread implantation.
		mice were killed and a piece of the tissue, 2 cm in diameter surrounding the implanted cotton thread including the skin, cutaneous muscle layer, subcutaneous tissues, the granulation tissue together with the cotton thread, was dissected 0 and 5 d after cotton thread implantation.
	www.jem.org /cgi/content/full/195/8/973 (4634 words)

	Granulation tissue (Site not responding. Last check: 2007-10-11)
		The term granulation tissue is derived from the appearance of small, red, granular foci which bleed easily, commonly seen within freshly healing tissue.
		The granulations consist of clusters of fragile newly-formed capillary blood vessels which proliferate and grow into damaged tissue along with fibroblasts at an early stage of the repair process.
		This area of granulation tissue contains a population of chronic inflammatory cells in addition to the vascular and fibroblastic elements, illustrating that inflammation and healing are very commonly concurrent.
	medweb.bham.ac.uk /http/depts/path/Teaching/FOUNDAT/repair/grantiss.html (254 words)

	Abscess-Forming Inflammatory Granulation Tissue with Gram-Positive Cocci and Prominent Eosinophil Infiltration in Cats: ...
		tissue or lymph nodes of the neck (9/27, 33%).
		Abscesses caused by infection with pyogenic microorganisms is
		Fibrosing granulation tissue is characteristic of the mass lesion.
	www.vetpathology.org /cgi/content/full/40/3/283 (1656 words)

	Expression of N-acetyltransferases in Periodontal Granulation Tissue -- Meisel et al. 81 (5): 349 -- Journal of Dental ...
		Expression of N-acetyltransferases in Periodontal Granulation Tissue -- Meisel et al.
		of a mucoperiosteal flap, the periodontal granulation tissue
		bands were observed in both granulation tissue and liver.
	jdr.iadrjournals.org /cgi/content/full/81/5/349 (2476 words)

	Mechanical Tension Controls Granulation Tissue Contractile Activity and Myofibroblast Differentiation -- Hinz et al. ...
		Tissue from splinted wounds (continuous line) exhibits significantly higher contractility already at early stages of development (6 days) and maintains high levels of contractility up to 10 days after wounding compared to unsplinted granulation tissue (dashed line).
		In 3-day-old unsplinted granulation tissue (Aa) fibroblastic cells exhibit low levels of de novo-appearing F-actin and ED-A FN whereas fibroblasts in 3-day splinted tissue (Ae) already show important expression and co-localization of the two proteins (yellow); co-localization is also seen in vascular smooth muscle cells (Aa, arrowhead).
		Extracts of 3- to 12-day-old granulation tissue from splinted wounds (sp) are compared to those of unsplinted wounds (un) and of normal dermis (derm).
	ajp.amjpathol.org /cgi/content/full/159/3/1009 (6043 words)

	Granuloma inguinale (Site not responding. Last check: 2007-10-11)
		Granulation tissue is tissue formed during wound healing that is rich in blood capillaries and has a rough or lumpy surface.
		A kind of tissue formed during wound healing, with a rough or irregular surface and a rich supply of blood capillaries.
		An inflammatory swelling or growth composed of granulation tissue, as in granuloma inguinale.
	www.healthatoz.com /healthatoz/Atoz/ency/granuloma_inguinale.jsp (1196 words)

	Successful Use of Argon Plasma Coagulation and Tranilast To Treat Granulation Tissue Obstructing the Airway After ...
		Excessive growth of granulation tissue at anastomosis is a common
		granulation with a flexible bronchoscope (Fig 2, b and c).
		Excessive growth of granulation tissue at the anastomosis was observed at 2 months (b) and 4 months (c) after surgery.
	www.chestjournal.org /cgi/content/full/118/6/1829 (1225 words)

	Removal granulation tissue root planing updated (Site not responding. Last check: 2007-10-11)
		The removal of the granulation tissue is a time-consuming and demanding procedure.
		The root surfaces are carefully cleaned and granulation tissue in craters is removed.
		Granulation tissue has formed into the defect which is thoroughly cleaned.
	cert.od.mah.se /vip/videonet_prog4/videonet43.html (359 words)

	Proud Flesh
		The problem with caustic substances is that their purpose is to destroy cells, and in addition to destroying exuberant granulation tissue, they also destroy healthy cells and might cause further damage to the wound.
		The surgical method is generally preferred because it removes much of the unwanted granulated tissue and leaves healthy tissue underneath, whereas the caustic method destroys all cells whether or not they need to be destroyed.
		Once the excess granulation tissue is removed, a steroid cream or ointment is applied to the area.
	www.netpets.com /horses/healthspa/flesh.html (864 words)

	Fibroblasts from the inner granulation tissue of the pseudocapsule in hips at revision arthroplasty induce osteoclast ...
		The inner granulation tissue of the pseudocapsule was harvested,
		In the co-culture of NA-BMCs and granulation fibroblasts in the presence of 1
		The granulation tissues inside the pseudocapsule were immunostained by anti-RANKL antibody (A) and control (B).
	ard.bmj.com /cgi/content/full/61/2/103 (4099 words)

	Oley Foundation
		When my son, Sean, gets granulation tissue, we apply a very tiny amount of this directly to the tissue, 4x per day, and usually within a day or two it is completely gone.
		Back when we cleaned with diluted hydrogen peroxide he was more likely to grow granulation tissue, and since switching he has not had a problem but the one time he had to have a g-tube instead of a button.
		Talk a short piece of toilet tissue (1 to 2 squares, depending upon how "plush" it is.) Roll it up into a string effect and then wrap that around the g-tube.
	www.oley.org /lifeline/Tissue.html (1023 words)

	Regulation of {alpha}-Smooth Muscle Actin Expression in Granulation Tissue Myofibroblasts Is Dependent on the Intronic ...
		Regulation of {alpha}-Smooth Muscle Actin Expression in Granulation Tissue Myofibroblasts Is Dependent on the Intronic CArG Element and the Transforming Growth Factor-{beta}1 Control Element -- Tomasek et al.
		granulation tissue of cutaneous wounds in a pattern that closely
		expression in myofibroblasts in granulation tissue and responsiveness
	ajp.amjpathol.org /cgi/content/abstract/166/5/1343 (265 words)

	Medical Dictionary: Granulation tissue - WrongDiagnosis.com
		Granulation tissue: new connective tissue and tiny blood vessels that form on the surfaces of a wound during the healing process
		Terms that may be interchangeable with Granulation tissue:
		The following list attempts to classify Granulation tissue into categories where each line is subset of the next.
	www.wrongdiagnosis.com /medical/granulation_tissue.htm (202 words)

	Photodynamic therapy for granulation tissue destruction 10 years after stent placement CHEST - Find Articles (Site not responding. Last check: 2007-10-11)
		A common complication of stent placement is granulation tissue reaction that can occlude stents.
		Symptoms from granulation tissue airway obstruction can limit the quality of life of these patients.
		PDT provided an extensive rapid elimination of granulation tissue as an outpatient using a flexible bronchoscope.
	www.findarticles.com /p/articles/mi_m0984/is_4_128/ai_n15792173 (403 words)

	Reducing ischaemic damage in rodent ovarian xenografts transplanted into granulation tissue -- Israely et al. 21 (6): ...
		tissue damage was confined to the graft centre.
		Effect of granulation tissue on ovarian grafts (days 1 and 2 after transplantation).
		Pedersen T and Peters H (1968) Proposal for a classification of oocytes and follicles in the mouse ovary.
	humrep.oxfordjournals.org /cgi/content/full/21/6/1368 (6332 words)

	Diffusion-Weighted Imaging for Differentiating Recurrent Cholesteatoma from Granulation Tissue after Mastoidectomy: ...
		from postoperative granulation tissue is important in a patient
		granulation tissue on the basis of diffusion-weighted imaging
		Axial view CT scan shows soft tissue (arrow) filling the postoperative mastoidectomy bowl and extending medially to the middle ear cavity.
	www.ajnr.org /cgi/content/full/23/5/847 (1324 words)

	granulation tissue definition - Dictionary - MSN Encarta
		granulation tissue definition - Dictionary - MSN Encarta
		healing tissue: connective tissue in the form of small grainy particles along with masses of tiny blood vessels that forms over healing wounds
		Everest: Beyond the Limit on the Discovery Channel
	encarta.msn.com /dictionary_1861691136/granulation_tissue.html (69 words)

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