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Topic: Granulocytopenia

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	Granulocytopenia and thrombocytopenia associated with combination therapy of amphotericin B and low-dose flucytosine ...
		Granulocytopenia and thrombocytopenia associated with combination therapy of amphotericin B and low-dose flucytosine in a patient with cryptococcal meningitis -- Shindo et al.
		Granulocytopenia and thrombocytopenia associated with combination therapy of amphotericin B and low-dose flucytosine in a patient with cryptococcal meningitis
		Both amphotericin B and low-dose flucytosine (50 mg/kg/d) were concomitantly administered to the patient and his clinical symptoms improved.
	www.theannals.com /cgi/content/abstract/23/9/672 (157 words)

	Pathogenic effects of monocytopenia, granulocytopenia and dexamethasone on the course of experimental Pseudomonas ... (Site not responding. Last check: 2007-10-27)
		Pathogenic effects of monocytopenia, granulocytopenia and dexamethasone on the course of experimental Pseudomonas aeruginosa endocarditis in rabbits.
		Pathogenic effects of monocytopenia, granulocytopenia and dexamethasone on the course of experimental Pseudomonas aeruginosa endocarditis in rabbits.Intravegetation inflammatory cell influxes were scored on a semiquantitative histopathologic scale.
		In VP-16-213 and dexamethasone recipients and tricuspid endocarditis controls, gradual decreases in mean intravegetation bacterial densities were observed over a 13-day infection period; in contrast, HN2 treatment was associated with a significant increase in intravegetation bacterial densities by day 13 of infection (p less than 0.001 vs. other tricuspid endocarditis groups).
	www.pdg.cnb.uam.es /UniPub/iHOP/gp/6160372.html (206 words)

	Granulocytopenia - Talk Medical (Site not responding. Last check: 2007-10-27)
		Granulocytopenia: A marked decrease in the number of granulocytes.
		Granulocytopenia or, as it is also called, agranulocytosis results in a syndrome of frequent chronic bacterial infections of the skin, lungs, throat etc. Although "agranulocytosis" literally means no granulocytes, there may, in fact, be some granulocytes but too few of them, i.e.
		Granulocytopenia can be genetic and inherited or it can be acquired as, for example, an aspect of leukemia.
	www.talkmd.com /medical-dictionary/print-6345 (231 words)

	Reversible granulocytopenia in association with riluzole therapy -- North et al. 34 (3): 322 -- The Annals of ...
		Reversible granulocytopenia in association with riluzole therapy -- North et al.
		Granulocytopenia was diagnosed and evaluation for a possible causative infectious process was negative; riluzole was considered a possible offender.
		CONCLUSIONS: Granulocytopenia has been reported as an adverse effect of riluzole but is not a complication well known to clinicians, and there are no detailed reports published in the literature.
	www.theannals.com /cgi/content/abstract/34/3/322 (243 words)

	Granulocytopenia (Site not responding. Last check: 2007-10-27)
		Because of the risk of agranulocytosis and granulocytopenia associated with the use of clozapine, Alamo Pharmaceuticals has developed a monitoring system...
		Granulocytopenia, paresthesia, diarrhea, vomiting, and nausea were the most common grade 3 or 4 adverse events.
		There were no reported cases of grade 3 or 4 rash or granulocytopenia, low levels of granulocytes, a type of white blood cell.
	health.cancer-help.org /news/Granulocytopenia.html (160 words)

	Government and academic resources on Granulocytopenia (Site not responding. Last check: 2007-10-27)
		Evaluation of Patients with HIV Infection and Granulocytopenia...
		The causes of grade 4 toxicity were granulocytopenia (5),...
		Granulocytopenia and anemia in up to 45% of patients.
	books.mongabay.com /health/conditions/Granulocytopenia.html (342 words)

	granulocytopenia (Site not responding. Last check: 2007-10-27)
		There is no consensus as to appropriate management in cases of persistent granulocytopenia when the patient is afebrile.
		Cancer.gov See Chemotherapy; WBC no greater than 30,000/mm 3; Patients with granulocytopenia, anemia, and/or thrombocytopenia are eligible but are not evaluable for...
		Compli- cations that were encountered during treatment in- cluded transient hepatic and renal insufficiency, granulocytopenia, thrombocytopenia, and bilateral...
	www.cancer-help.org /cancer/0604/granulocytopenia.html (364 words)

	Vesnarinone-induced granulocytopenia: incidence in Japan and recommendations for safety -- Furusawa et al. 36 (5): 477 ...
		This article reviews the results of this post-marketing surveillance and other works available to date, including an illustrative case report, and presents measures that should be taken with regard to safety during treatment with vesnarinone.
		Vesnarinone-induced granulocytopenia has appeared in relatively early stages of vesnarinone therapy, and characteristically results in a rapid decrease in granulocyte count.
		Granulocyte colony-stimulating factor may contribute to recovery from severe granulocytopenia, although it should be used carefully because of its potential to cause adult respiratory distress syndrome.
	www.jclinpharm.org /cgi/content/abstract/36/5/477 (275 words)

	Prognostic significance of changes in serum transcobalamin levels in cancer patients with chemotherapy-induced ... (Site not responding. Last check: 2007-10-27)
		Prognostic significance of changes in serum transcobalamin levels in cancer patients with chemotherapy-induced granulocytopenia.
		Prognostic significance of changes in serum transcobalamin levels in cancer patients with chemotherapy-induced granulocytopenia.The rise in serum TCII level appears to be an early indicator for imminent bone marrow recovery in myelosuppressed patients.
		A significant increase in serum TCII level was observed in all patients, with peak values occurring an average of 4.5 days from admission at a time when the median leukocyte count was 2,300/mm 3.
	www.pdg.cnb.uam.es /UniPub/iHOP/gp/4468796.html (159 words)

	AEGiS-15IAC: Granulocytopenia associated with cotrimoxazole prophylaxis in a community based clinic, Entebbe, Uganda.
		AEGiS-15IAC: Granulocytopenia associated with cotrimoxazole prophylaxis in a community based clinic, Entebbe, Uganda.
		Granulocytopenia associated with cotrimoxazole prophylaxis in a community based clinic, Entebbe, Uganda.
		CONCLUSIONS: Prophylactic cotrimoxazole use in HIV infected adults in Uganda was associated with granulocytopenia.
	www.aegis.com /conferences/iac/2004/MoPeB3148.html (355 words)

	Lithium and granulocytopenia during induction therapy of acute myelogenous leukemia -- Stein et al. 54 (3): 636 -- Blood
		Lithium and granulocytopenia during induction therapy of acute myelogenous leukemia -- Stein et al.
		Articles by Stein, R. Articles by Graber, S. Lithium and granulocytopenia during induction therapy of acute myelogenous leukemia
		granulocytopenia, less than 1000/cu mm, was 16.0 days in the lithium group
	www.bloodjournal.org /cgi/content/abstract/54/3/636 (175 words)

	IngentaConnect Pathogenesis of Granulocytopenia and Bone Marrow Atrophy during C...
		Pathogenesis of Granulocytopenia and Bone Marrow Atrophy during Classical Swine Fever Involves Apoptosis and Necrosis of Uninfected Cells
		Granulocytopenia, a hematological hallmark of classical swine fever, is partially responsible for the suppression of innate immune defenses during classical swine fever.
		Taken together, the results demonstrate that granulocytopenia and bone marrow atrophy are mediated by hematopoietic cell death and that indirect virus–host-mediated mechanisms are likely to be responsible.
	www.ingentaconnect.com /content/ap/vy/2000/00000272/00000001/art00361 (318 words)

	Welcome to the DPD-Deficiency Webpage (Site not responding. Last check: 2007-10-27)
		Unanticipated Toxicity to 5-FU Several reports have described an inherited (pharmacogenetic) disorder in which individuals with absent or significantly decreased DPD activity develop life-threatening toxicity following exposure to 5-FU.
		Since the catabolic pathway does not function in DPD deficient patients, administration of standard doses of 5-FU results in altered 5-FU pharmacokinetics and severe toxicity including mucositis, granulocytopenia, neuropathy and death.
		The cause for this toxicity appears to be decreased drug clearance, resulting in markedly prolonged exposure to 5-FU.
	www.dpdenzyme.com (367 words)

	Arch Intern Med -- Abstract: Granulocyte colony-stimulating factor treatment of antithyroid drug-induced ... (Site not responding. Last check: 2007-10-27)
		Arch Intern Med -- Abstract: Granulocyte colony-stimulating factor treatment of antithyroid drug-induced granulocytopenia, February 22, 1993, Tajiri et al.
		granulocyte counts were zero, did not recover from granulocytopenia until
		granulocytopenia and one with moderate granulocytopenia at the onset of
	archinte.ama-assn.org /cgi/content/abstract/153/4/509 (244 words)

	Efficacy and Toxicity of Single Daily Doses of Amikacin and Ceftriaxone versus Multiple Daily Doses of Amikacin and ...
		of febrile patients with cancer and granulocytopenia, to whom
		Ceftazidime combined with a short or long course of amikacin for empirical therapy of gram-negative bacteremia in cancer patients with granulocytopenia.
		Randomized trial of empiric antibiotic therapy with ticarcillin in combination with gentamicin, amikacin or netilmicin in febrile patients with granulocytopenia and cancer.
	www.annals.org /cgi/content/full/119/7_Part_1/584 (6106 words)

	Arch Intern Med -- Abstract: Empiric therapy for infections in patients with granulocytopenia. Continuous v interrupted ...
		Arch Intern Med -- Abstract: Empiric therapy for infections in patients with granulocytopenia.
		Empiric therapy for infections in patients with granulocytopenia.
		Carbenicillin sodium or ticarcillin disodium was substituted for
	archinte.ama-assn.org /cgi/content/abstract/144/5/1005 (236 words)

	Granulocytopenia (Site not responding. Last check: 2007-10-27)
		Granulocytopenia - Granulocytopenia is defined as a reduced number of blood granulocytes,
		Granulocytopenia or, as it is also called, agranulocytosis results in a syndrome
		Granulocytopenia associated with neuroleptic therapy in a patient...
	www.cougarhealth.com /health_topics/Granulocytopenia.html (302 words)

	1300 -- N-Desmethylclozapine, an Insensitive Marker of Clozapine-Induced Agranulocytosis and Granulocytopenia (Site not responding. Last check: 2007-10-27)
		Michael D. Combs, Pharm.D., Paul J. Perry, Ph.D., and Kristine A. Bever, Pharm.D. We reviewed the charts of 58 patients with treatment-refractory schizophrenia who were receiving clozapine, to determine if the drug's active metabolite, N-desmethylclozapine, is a biologic marker for impending clozapine-induced granulocytopenia and agranulocytosis.
		No significant correlation between granulocyte counts and patient demographic variables of clozapine and N-desmethylclozapine steady-state plasma concentrations, clozapine:N-desmethylclozapine ratio, age, gender, clozapine dosage, smoking status, and race were found.
		On the contrary, its plasma concentrations correlated positively with granulocyte counts.
	www.accp.com /pharmacotherapy/Abs17_6/1300.htm (123 words)

	Clinical Trial: Liposomal Amphotericin B in Treating Granulocytopenia and Persistent Unexplained Fever in Cancer ...
		It is not yet known which regimen of liposomal amphotericin B is more effective in treating cancer patients who have these conditions.
		PURPOSE: Randomized phase III trial to compare the effectiveness of two regimens of liposomal amphotericin B in treating granulocytopenia and fever in cancer patients.
		Compare the efficacy and side effects of amphotericin B-liposomal formulation initiated 72-84 hours vs 144-156 hours after onset of a febrile episode in cancer patients with granulocytopenia and persistent unexplained fever refractory to antibacterials.
	clinicaltrials.gov /show/NCT00003938 (536 words)

	eMedicine - Granulocytopenia : Article Excerpt by: Kush Sachdeva, MD
		Please click here to view the full topic text: Granulocytopenia
		Background: Granulocytopenia is defined as a reduced number of blood granulocytes, namely neutrophils, eosinophils, and basophils.
		The term granulocytopenia often is used synonymously with neutropenia.
	www.emedicine.com /med/byname/granulocytopenia.htm (535 words)

	Non-Menkes-type copper deficiency with regression, lactic acidosis, and granulocytopenia -- Fujii et al. 41 (8): 1263 ...
		Non-Menkes-type copper deficiency with regression, lactic acidosis, and granulocytopenia -- Fujii et al.
		Non-Menkes-type copper deficiency with regression, lactic acidosis, and granulocytopenia
		A 2-year-old girl with granulocytopenia developed fever followed by truncal
	www.neurology.org /cgi/content/abstract/41/8/1263 (146 words)

	Arch Dermatol -- Abstract: Neutrophilic dermatoses during granulocytopenia, October 1995, Aractingi et al. 131 (10): ...
		Arch Dermatol -- Abstract: Neutrophilic dermatoses during granulocytopenia, October 1995, Aractingi et al.
		occur during granulocytopenia, but their mechanism remains unknown.
		developed during granulocytopenia induced by chemotherapy for acute
	archderm.ama-assn.org /cgi/content/abstract/131/10/1141 (140 words)

	Empiric treatment of infection during granulocytopenia -- Klastersky 1 (4): 255 -- Annals of Oncology
		Empiric treatment of infection during granulocytopenia -- Klastersky 1 (4): 255 -- Annals of Oncology
		patients, especially in those with severe and persistent granulocytopenia
		granulocytopenia and protracted fever whose blood cultures remain negative
	annonc.oupjournals.org /cgi/content/abstract/1/4/255 (308 words)

	eMedicine - Granulocytopenia : Article by Kush Sachdeva, MD
		Hughes WT, Armstrong D, Bodey GP: 1997 guidelines for the use of antimicrobial agents in neutropenic patients with unexplained fever.
		Kern WV, Cometta A, De Bock R: Oral versus intravenous empirical antimicrobial therapy for fever in patients with granulocytopenia who are receiving cancer chemotherapy.
		In particular, all drug doses, indications, and contraindications should be confirmed in the package insert.
	www.emedicine.com /med/topic927.htm (3363 words)

	Effect of recombinant human granulocyte colony-stimulating factor on granulocytopenia in mice … (Site not responding. Last check: 2007-10-27)
		Effect of recombinant human granulocyte colony-stimulating factor on granulocytopenia in mice andhellip;
		Leukocytopenia news vertical portal can now be syndicated quickly and easily using our new Really Simple Syndication feeds.
		For any further understanding that could lead to the prevention, treatment, and/or cure of the disorders, we recommend that affected individuals seek the advice or counsel of his or her own personal physician(s).
	leukocytopenia.diseasemap.com /page_80338.html (145 words)

	Cell mediated autoimmune granulocytopenia in a case of Felty's syndrome -- Slavin and Liang 39 (4): 399 -- Annals of ...
		Cell mediated autoimmune granulocytopenia in a case of Felty's syndrome -- Slavin and Liang 39 (4): 399 -- Annals of the Rheumatic Diseases
		Cell mediated autoimmune granulocytopenia in a case of Felty's syndrome
		A variety of mechanisms have been demonstrated or suggested to explain the
	ard.bmjjournals.com /cgi/content/abstract/39/4/399 (133 words)

	Interleukin-1-induced granulocytopenia and pulmonary leukostasis in rabbits -- Goldblum et al. 62 (1): 122 -- Journal ...
		Interleukin-1-induced granulocytopenia and pulmonary leukostasis in rabbits -- Goldblum et al.
		administration induced significant (P less than 0.01) granulocytopenia
		granulocytopenia followed by later granulocytosis, as well as sustained
	jap.physiology.org /cgi/content/abstract/62/1/122 (221 words)

	NEJM -- Oral versus Intravenous Empirical Antimicrobial Therapy for Fever in Patients with Granulocytopenia Who Are ...
		NEJM -- Oral versus Intravenous Empirical Antimicrobial Therapy for Fever in Patients with Granulocytopenia Who Are Receiving Cancer Chemotherapy
		Oral versus Intravenous Empirical Antimicrobial Therapy for Fever in Patients with Granulocytopenia Who Are Receiving Cancer Chemotherapy
		randomly assigned febrile patients with cancer who had granulocytopenia
	content.nejm.org /cgi/content/abstract/341/5/312? (1172 words)

	CiteULike: Inflammatory pseudotumor of the liver in a patient with congenital granulocytopenia and HCV infection (Site not responding. Last check: 2007-10-27)
		CiteULike: Inflammatory pseudotumor of the liver in a patient with congenital granulocytopenia and HCV infection
		Inflammatory pseudotumor of the liver in a patient with congenital granulocytopenia and HCV infection
		Schneider G, Fries P, Samaras P, Remberger K, Uder M, Kramann B
	www.citeulike.org /article/49589 (76 words)

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