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Topic: Guanosine monophosphate


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  Method for stimulation or repair and regeneration of intestinal gut cells in infants and enhancing the immune response ...
______________________________________ uridine and/or uridine phosphate 17.40-1.86 mg; guanosine and/or guanosine phosphate 3.32-0.27 mg; adenosine and/or adenosine phosphate 9.50-4.25 mg; cytidine and/or cytidine phosphate 10-16-3.52 mg; and inosine and/or inosine phosphate 1.92-0.00 mg.
______________________________________ uridine and/or uridine phosphate 2.62-0.28 mg; guanosine and/or guanosine phosphate 0.50-0.04 mg; adenosine and/or adenosine phosphate 1.43-0.64 mg; cytidine and/or cytidine phosphate 1.53-0.53 mg; and inosine and/or inosine phosphate 0.29-0.00 mg.
______________________________________ uridine and/or uridine phosphate 2.62-0.28 mg; guanosine and/or guanosine phosphate 0.50-0.04 mg; adenosine and/or adenosine phosphate 0.56-0.00 mg; cytidine and/or cytidine phosphate 0.69-0.00 mg; and inosine and/or inosine phosphate 0.29-0.00 mg.
www.freepatentsonline.com /4994442.html   (6879 words)

  
 Guanosine monophosphate - Wikipedia, the free encyclopedia
Guanosine monophosphate, also known as 5'-guanidylic acid or guanylic acid and abbreviated GMP, is a nucleotide that is found in RNA.
It is an ester of phosphoric acid with the nucleoside guanosine.
GMP consists of the phosphate group, the pentose sugar ribose, and the nucleobase guanine.
en.wikipedia.org /wiki/Guanosine_monophosphate   (98 words)

  
 GUANINE (2-AMINO-6-HYDROXYPURINE)
Guanosine diphosphate (GDP) : a nucleotide composed of pyrophosphate of guanosine which serves as a carrier for mannose residues in glycoprotein synthesis and as a substrate for a phosphorylation reaction of the tricarboxylic acid cycle.
Guanosine monophosphate (GMP, aso known as guanylic acid) : a nucleotide composed of pyrophosphate of guanosine which is formed during the hydrolysis of nucleic acidis and is a regulator of pyrimidine nucleotide biosynthesis.
Cyclic guanosine monophosphate (cGMP); 3',5'-cyclic ester of guanosine monophosphate that serves as an intracellular secondary involved its direct effects on Na+ and Ca2+ channels in the plasma membrane of rod cells.
www.chemicalland21.com /lifescience/phar/GUANINE.htm   (835 words)

  
 guanosine
The company is developing Viramidine, a nucleoside (guanosine) analog, in oral form for administration in combination with pegylated interferon for the...
Garg UC, Hassid A. Nitric oxide-generating vasodilators and 8- bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat...
Valeant is developing Viramidine, a nucleoside (guanosine) analog, in oral form for the treatment of chronic hepatitis C in conjunction with a pegylated...
www.mongabay.com /igapo/biotech/guanosine.html   (409 words)

  
 Highbeam Encyclopedia - Search Results for guanosine
The accepted structure of the guanine molecule was proposed in 1875, and the compound was first synthesized in 1900.
Find newspaper and magazine articles plus images and maps related to "guanosine" at HighBeam.
Catastrophic cardiovascular adverse reactions to protamine are nitric oxide/cyclic guanosine monophosphate dependent and endothelium mediated *: should methylene blue be the treatment of choice?
www.encyclopedia.com /searchpool.asp?target=guanosine   (222 words)

  
 Nucleoside derivatives and an antileukemial agent containing the same as an active ingredient - Patent 4297347
A 3'-polyphosphate of pyrimidine nucleoside or guanosine or a pharmaceutically acceptable salt thereof which has high antileukemial activity and is low in toxicity is disclosed.
Nucleosides occur in all living cells as a component of nucleic acid, and the nucleotide which is the class of esters formed by interacting nucleosides with phosphoric acid has been the subject of many studies conducted to date, but adenosine has been the only nucleoside from which 3'-polyphosphates (e.g.
The inventors of this invention have succeeded in preparing a novel nucleoside-3'-polyphosphate by first converting 3'-monophosphate of pyrimidine nucleoside or guanosine to the corresponding reactive derivative such as amidate or morpholidate in the conventional manner and esterifying the derivative with phosphoric acid.
www.freepatentsonline.com /4297347.html   (2422 words)

  
 REGULATORY CASCADES
The cyclic adenosine monophosphate (cAMP) cascade in the thyroid corresponds, as far as it has been studied, to the canonic model of the β-adrenergic receptor cascade (116) (Fig.
Activation of a G protein corresponds to its release of guanosine diphosphate (GDP) and binding of GTP and to its dissociation into αGTP and βγ dimers.
Of the other known possible effectors of cAMP, cyclic guanosine monophosphate (cGMP)-dependent protein kinases are present in the thyroid but cyclic nucleotide–activated channels have not been looked for.
www.thyroidmanager.org /Chapter1/ch01s07.html   (1666 words)

  
 Effect of sodium-potassium pump inhibitors and membrane-depolarizing agents on sodium nitroprusside-induced relaxation ...
Effect of sodium-potassium pump inhibitors and membrane-depolarizing agents on sodium nitroprusside-induced relaxation and cyclic guanosine monophosphate accumulation in rat aorta -- Rapoport et al.
Effect of sodium-potassium pump inhibitors and membrane-depolarizing agents on sodium nitroprusside-induced relaxation and cyclic guanosine monophosphate accumulation in rat aorta
of elevated cyclic guanosine monophosphate levels was independent of the
circres.ahajournals.org /cgi/content/abstract/57/1/164   (438 words)

  
 Cyclic guanosine monophosphate in heart failure- Dr. Max Pichler   (Site not responding. Last check: 2007-10-13)
Sir,- Dr Lerman and colleagues' report (May 1, p 1105) on circulating N-terminal atrial natriuretic peptide as a marker for symptomless left-ventricular dysfunction, and your accompanying commentary by Professor Barnett on the diagnosis of symptomless left-ventricular dysfunction, prompt us to draw attention to another promising analyte for diagnosing and monitoring heart failure-cyclic guanosine monophosphate (cGMP).
Once released from the heart, natriuretic peptides exert potent direct vasodilator and natriuretic actions by virtue of their ability to increase their intracellular second messenger cGMP (1).
Release of cyclic guanosine monophosphate evaluated as a diagnostic tool in cardiac disease.
www.lipidforum.at /Wissenschaft/Experten/pichler1.htm   (561 words)

  
 Natriuretic peptides stimulate cyclic guanosine monophosphate production in human saphenous vein and internal mammary ...   (Site not responding. Last check: 2007-10-13)
Natriuretic peptides stimulate cyclic guanosine monophosphate production in human saphenous vein and internal mammary artery -- Bonatti et al.
that C-type natriuretic peptide possesses a cyclic guanosine
of cyclic guanosine monophosphate were determined using an
ejcts.ctsnetjournals.org /cgi/content/abstract/17/2/175   (412 words)

  
 Regulation of interleukin-1{beta} and interleukin-1{beta} inhibitor release by human airway epithelial cells -- Yang et ...
2.— Effect of a) dibutyryl cyclic adenosine monophosphate (cAMP) and b) 8-bromo-cyclic guanosine monophosphate (cGMP) on interleukin (IL)-1ß release by 16-HBE cells.
3.— Effect of a) dibutyryl cyclic adenosine monophosphate (cAMP) and b) 8-bromo-cyclic guanosine monophosphate (cGMP) on interleukin-1 receptor antagonist (IL-1RA) release by 16-HBE cells.
Prostaglandins post-transcriptionally inhibit monocyte expression of interleukin-1 activity by increasing intracellular cyclic adenosine monophosphate.
erj.ersjournals.com /cgi/content/full/24/3/360   (2684 words)

  
 Is Measurement of Cyclic Guanosine Monophosphate in Plasma or Urine Suitable for Assessing In Vivo Nitric Oxide ...
Murad F. Signal transduction using nitric oxide and cyclic guanosine monophosphate.
Hamet P, Pang SC, Tremblay J. Atrial natriuretic factor-induced egression of cyclic guanosine monophosphate in cultured vascular smooth muscle and endothelial cells.
Determinants of aortic cyclic guanosine monophosphate in hypertension induced by chronic inhibition of NO synthase.
circ.ahajournals.org /cgi/content/full/97/12/1209   (1697 words)

  
 Mode of action   (Site not responding. Last check: 2007-10-13)
Nitric Oxide (NO) is released with sexual stimulation from nerve endings and endothelial cells in the spongy erectile tissue, the corpus cavernosum of the penis.
The enzyme guanylate cyclase then converts guanosine triphosphate (GTP) into cyclic guanosine monophosphate (cGMP).
Sidenafil is selective for the enzyme phosphodiesterase of type 5 : its effect is more potent on PDE5 than on the other known PDE enzymes.
www.ch.ic.ac.uk /local/projects/p_hazel/mode2.html   (724 words)

  
 Medical Dictionary: Guanosine monophosphate - WrongDiagnosis.com - WrongDiagnosis.com
Guanosine monophosphate : guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.
The term Guanosine monophosphate can be used for:
The description of Guanosine monophosphate may also be used for the following terms:
www.wrongdiagnosis.com /medical/guanosine_monophosphate_printer.htm   (94 words)

  
 Cyclic Guanosine Monophosphate: Effects on Short-Circuit Current and Water Permeability -- Bourgoignie et al. 165 ...
Cyclic Guanosine Monophosphate: Effects on Short-Circuit Current and Water Permeability -- Bourgoignie et al.
Cyclic Guanosine Monophosphate: Effects on Short-Circuit Current and Water Permeability
In the isolated toad bladder, cyclic guanosine monophosphate
www.sciencemag.org /cgi/content/abstract/165/3900/1362   (236 words)

  
 Distinct regulation of nitric oxide and cyclic guanosine monophosphate production by steroid hormones in the rat uterus ...
Twort, C.H. and van Breemen, C. (1988) Cyclic guanosine monophosphate-enhanced sequestration of Ca2+ by sarcoplasmic reticulum in vascular smooth muscle.
Weiner, C.P., Knowles, R.G., Nelson, S.E. and Stegink, L.D. (1994a) Pregnancy increases guanosine 3',5'-monophosphate in the myometrium independent of nitric oxide synthesis.
Yallampalli, C., Izumi, H., Byam-Smith, M. and Garfield, R.E. (1994) An -arginine-nitric oxide-cyclic guanosine monophosphate system exists in the uterus and inhibits contractility during pregnancy.
molehr.oxfordjournals.org /cgi/content/full/6/5/404   (6285 words)

  
 Biochemistry of Nucleic Acids
Many modified nucleotides are encountered outside of the context of DNA and RNA that serve important biological functions.
The most common adenosine derivative is the cyclic form, 3'-5'-cyclic adenosine monophosphate, cAMP.
This compound is a very powerful second messenger involved in passing signal transduction events from the cell surface to internal proteins, e.g.
www.indstate.edu /thcme/mwking/nucleic-acids.html   (2097 words)

  
 Catastrophic Cardiovascular Adverse Reactions to Protamine Are Nitric Oxide/Cyclic Guanosine Monophosphate Dependent ...
Catastrophic Cardiovascular Adverse Reactions to Protamine Are Nitric Oxide/Cyclic Guanosine Monophosphate Dependent and Endothelium Mediated
the response of intracellular secondary messengers (cyclic guanosine
Abbreviations: cGMP = cyclic guanosine monophosphate; EDRF =
www.chestjournal.org /cgi/content/full/122/3/1061   (2240 words)

  
 Role of Cyclic Guanosine Monophosphate in Late Preconditioning in Conscious Rabbits -- Kodani et al. 105 (25): 3046 -- ...
Role of Cyclic Guanosine Monophosphate in Late Preconditioning in Conscious Rabbits -- Kodani et al.
Role of Cyclic Guanosine Monophosphate in Late Preconditioning in Conscious Rabbits
Xian-Liang Tang, MD Roberto Bolli, MD From the Experimental Research Laboratory, Division of Cardiology, University of Louisville and the Jewish Heart and Lung Institute, Louisville, Ky.
circ.ahajournals.org /cgi/content/abstract/105/25/3046   (385 words)

  
 Viagra: - Resumos Clínicos - Medstudents
VIAGRA™, an oral therapy for erectile dysfunction, is the citrate salt of sildenafil, a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5).
NO then activates the enzyme guanylate cyclase, which results in increased levels of cyclic guanosine monophosphate (cGMP), producing smooth muscle relaxation in the corpus cavernosum and allowing inflow of blood.
Sildenafil has no direct relaxant effect on isolated human corpus cavernosum, but enhances the effect of nitric oxide (NO) by inhibiting phosphodiesterase type 5 (PDE5), which is responsible for degradation of cGMP in the corpus cavernosum.
www.medstudents.com.br /abstracts/viagra/info.htm   (3994 words)

  
 INHALED NITRIC OXIDE FAILS TO CONFER THE PULMONARY PROTECTION PROVIDED BY DISTAL STIMULATION OF THE NITRIC OXIDE ...
guanosine monophosphate pathway at the level of cyclic guanosine
monophosphate might confer the beneficial vascular effects of
monophosphate has a protective effect that is not seen with
jtcs.ctsnetjournals.org /cgi/content/abstract/110/5/1434   (918 words)

  
 nucleotide mixture(nucleotide) - Shanghai Xianlei Bioscience and Biotechnology Co.,Ltd.
Shanghai Xianlei Bioscience and Biotechnology Co.,Ltd. Home : Products Product Description: nucleotide mixture(nucleotide), white crystalline powder, constituted of adenosine monophosphate disodium, guanosine monophosphate disodium, uridine monophosphate disodium, cytidine monophosphate disodium.
We also provide single mononucleotide, such as adenosine monophosphate(AMP), cytidine monophosphate(CMP), uridine monophosphate disodium(UMPNa2), guanosine monophosphate disodium(GMPNa2).
white crystalline powder, constituted of adenosine monophosphate disodium, guanosine monophosphate disodium, uridine monophosphate disodium, cytidine monophosphate disodium.
www.allproducts.com /manufacture97/xianleid/product1.html   (155 words)

  
 Chronic L-arginine treatment increases cardiac cyclic guanosine 5'-monophosphate in rats with aortic stenosis: effects ...
-arginine treatment increases cardiac cyclic guanosine 5'-monophosphate in rats with aortic stenosis: effects on left ventricular mass and beta-adrenergic contractile reserve
Carg UC, Hassid A. Nitric-oxide vasodilators and 8 bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells.
Increased guanylate cyclase activity is associated with an increase in cyclic guanosine 3',5'-monophosphate in left ventricular hypertrophy.
content.onlinejacc.org /cgi/content/full/32/2/528   (4077 words)

  
 Treating HCV with ribavirin analogues and ribavirin-like molecules -- Gish 57 (1): 8 -- Journal of Antimicrobial ...
ribavirin, a nucleoside analogue that inhibits inosine monophosphate
dGDP, deoxyguanosine diphosphate; GDP, guanosine diphosphate; GMP, guanosine monophosphate; GTP, guanosine triphosphate; HGPRT, hypoxanthine guanine phosphoribosyltransferase; IMP, inosine monophosphate; IMPDH, inosine monophosphate dehydrogenase; PNP, purine nucleoside phosphorylase; XMP, xanthosine monophosphate.
CTL, cytotoxic T lymphocytes; HCV, hepatitis C virus; IFN, interferon; IMP, inosine monophosphate; IMPDH, inosine monophosphate dehydrogenase; RDP, ribavirin diphosphate; RdRp, RNA-dependent RNA polymerase; RMP, ribavirin monophosphate; RTP, ribavirin triphosphate; TNF, tumour necrosis factor; RNA, ribonucleic acid.
jac.oxfordjournals.org /cgi/content/full/57/1/8   (2942 words)

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