Factbites
 Where results make sense
About us   |   Why use us?   |   Reviews   |   PR   |   Contact us  

Topic: Guanosine triphosphate


Related Topics

In the News (Mon 18 Dec 17)

  
  GUANOSINE
Guanosine Triphosphate (GTP) : a nucleotide composed of guanine, the sugar ribose, and three phosphate groups; the source of the guanosine found in RNA and also involved in many cellular processes, including microtubule assembly, protein synthesis, and cell signaling, due to the energy it releases upon removal of its terminal phosphate group (yielding GDP).
Guanosine diphosphate (GDP) : a nucleotide composed of pyrophosphate of guanosine which serves as a carrier for mannose residues in glycoprotein synthesis and as a substrate for a phosphorylation reaction of the tricarboxylic acid cycle.
Guanosine monophosphate (GMP, aso known as guanylic acid) : a nucleotide composed of pyrophosphate of guanosine which is formed during the hydrolysis of nucleic acidis and is a regulator of pyrimidine nucleotide biosynthesis.
www.chemicalland21.com /lifescience/phar/GUANOSINE.htm   (834 words)

  
 Attotron Molecular Biology Hypertext Dictionary
ddNTP.GIF a nucleoside triphosphate analog that causes termination of an elongating DNA molecule when incorporated by DNA polymerase because of the absence of a 3´-hydroxyl residue on the sugar portion of the compound, which is necessary for the formation of the 3' to 5' phosphate linkage in an elongating DNA chain.
The sugar molecules are modified by the presence of a purine or pyrimidine nucleoside or "base" attached to the first, or 1', carbon and the oxygen-phosphorus-oxygen bond links the third, or 3', carbon to the fifth, or 5', carbon of the adjacent sugar molecule.
thymidine triphosphate, a deoxyribose molecule with the pyrimidine thymine attached to the 1´ carbon and a chain of three oxygenated phosphorus atoms attached to the 5' carbon.
www.attotron.com /pub/dnaquiz/diction.htm   (9690 words)

  
 Guanosine Triphosphate, metabolism
Using purified bacterially expressed fusion proteins, we show, furthermore, that Ras and the N-terminal region of Raf associate directly in vitro and that this interaction is dependent on GTP bound to Ras.
Both mutant proteins were found to be associated with guanosine triphosphate (GTP) in vivo.
In contrast, Gly12 p21 was predominantly guanosine diphosphate (GDP)-bound because of a dramatic stimulation of Gly12 p21-associated guanosine triphosphatase (GTPase) activity.
lib.bioinfo.pl /meid:287   (2292 words)

  
 Pharmacological implications of aluminofluoride complexes
Aluminofluoride complexes have been widely used in laboratory investigations for stimulation of various guanine nucleotide binding proteins.
Their effect is more readily seen with G proteins because guanosine diphosphate (GDP) is always tightly bound in the site after the hydrolysis of guanosine triphosphate (GTP).
In aqueous solutions, the fluoride anions bind to metal cation and are exchangeable with free fluoride or hydroxyl ions.
www.fluoridation.com /brain3.htm   (3642 words)

  
 In Vitro Incorporation of Amino Acids into the Proteins of Isolated Nuclear Ribosomes.
This process requires adenosine triphosphate, amino acid activating enzymes, and guanosine triphosphate.
This procedure sediments the nuclear ribosome particles in the range 120-7000 S. The resulting supernate was brought to Ph 5.2 with 1 M acetic acid, and the precipitate collected as nuclear pH 5 amino acid activating enzymes (6).
The nuclear ribosome pellets were resuspended (by syringing) in a final volume of 2.0 ml of the incubation medium described above, to which was added 0.20 mg pyruvate kinase, 20 umoles of sodium phosphenolpyruvate, 2.0 umoles ATP (sodium salt), 1.0 umole guanosine triphosphate (sodium salt), DL-[1-
www.euchromatin.net /BBA01.htm   (2937 words)

  
  Abstract 306 - Mechanistic Studies of Dioxolane Guanosine 5´- Triphosphate: Implications for Efficacy, Lack of ...   (Site not responding. Last check: )
Abstract 306 - Mechanistic Studies of Dioxolane Guanosine 5´- Triphosphate: Implications for Efficacy, Lack of Cross- Resistance and Selectivity of DAPD.
306 Mechanistic Studies of Dioxolane Guanosine 5´- Triphosphate: Implications for Efficacy, Lack of Cross- Resistance and Selectivity of DAPD.
Background:DAPD, a prodrug of dioxolane guanosine (DXG), is a nucleoside analog currently in Phase I/II clinical trials for the treatment of HIV infection.
www.retroconference.org /2001/abstracts/abstracts/abstracts/306.htm   (366 words)

  
  Guanosine triphosphate - Wikipedia, the free encyclopedia
Guanosine triphosphate (GTP) is also known as guanosine-5'-triphosphate and G3P.
GTP is a purine nucleotide that is incorporated into the growing RNA chain during RNA synthesis, and used as a source of energy for protein synthesis.
GTP is also essential to signal transduction, where it is converted to GDP (guanosine diphosphate) through the action of GTPases.
en.wikipedia.org /wiki/Guanosine_triphosphate   (233 words)

  
 Guanosine - Wikipedia, the free encyclopedia
Guanosine is a nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N
Guanosine can be phosphorylated to become GMP (guanosine monophosphate), cGMP (cyclic guanosine monophosphate), GDP (guanosine diphosphate) and GTP (guanosine triphosphate).
When guanine is attached to a deoxyribose ring, it is known as a deoxyguanosine.
en.wikipedia.org /wiki/Guanosine   (184 words)

  
 [No title]   (Site not responding. Last check: )
OH guanosine, 100% of all cytidine nucleotides are 2'-0-methyl cytidine and 100% of all uridine nucleotides are 2'-O-methyl uridine.
guanosine, substantially all cytidine nucleotides are 2'-O-methyl cytidine, substantially all uridine nucleotides are 2'-0-methyl uridine, and substantially all adenosine nucleotides are 2'-O-methyl adenosine.
guanosine, at least 80% of all cytidine nucleotides are 2'-0-methyl cytidine, at least 80% of all uridine nucleotides are 2'-O-methyl uridine, and at least 80% of all adenosine nucleotides are 2'-O-methyl adenosine.
www.wipo.int /cgi-pct/guest/getbykey5?KEY=05/10150.050203&ELEMENT_SET=DECL   (8975 words)

  
 Guanosine - TheBestLinks.com - Guanine, Molecule, Deoxyribose, Ribose, ...   (Site not responding. Last check: )
Guanosine - TheBestLinks.com - Guanine, Molecule, Deoxyribose, Ribose,...
Guanosine is a molecule (known as a nucleoside) that is formed when guanine is attached to a ribose ring (also known as a ribofuranose) via a β-N
Guanosine can be phosphorylated to become GDP (guanosine diphosphate) and GTP (guanosine triphosphate) among other things.
www.thebestlinks.com /Guanosine.html   (111 words)

  
 Guanosine
Guanosine is a molecule (known as a nucleoside) that is formed when guanine is attached to a ribose ring (also known as a ribofuranose) via a β-N9-glycosidic bond.
Guanosine is involved with the direct preservation and transfer of chemical energy in living systems.
Guanosine is a nucleoside that consists of guanine, an organic base belonging to the purine family, and the sugar ribose.
www.greatvistachemicals.com /proteins-sugars-nucleotides/guanosine.html   (339 words)

  
 Guanine nucleosides and Jurkat cell death: roles of ATP depletion and accumulation of deoxyribonucleotides -- Batiuk et ...
Jurkat cells were incubated with 500 µM guanosine or deoxyguanosine for 8, 16, or 24 h.
Cells treated with guanosine or deoxyguanosine showed a mixture of necrotic features (yellow stain indicating inability to exclude propidium iodide due to damaged cell membrane, arrowheads) and apoptotic features (exclusion of propidium iodide and condensed and fragmented nuclei staining green with Hoechst 33343, arrows).
Effects of 8-aminoguanosine on the toxicity of guanosine and deoxyguanosine for malignant and normal lymphoid cells.
ajpcell.physiology.org /cgi/content/full/281/6/C1776   (4365 words)

  
 AllRefer.com - guanine (Biochemistry) - Encyclopedia   (Site not responding. Last check: )
When combined with the sugar ribose in a glycosidic linkage, guanine forms a derivative called guanosine (a nucleoside), which in turn can be phosphorylated with from one to three phosphoric acid groups, yielding the three nucleotides GMP (guanosine monophosphate), GDP (guanosine diphosphate), and GTP (guanosine triphosphate).
GTP acts as a coenzyme in carbohydrate metabolism and in the biosynthesis of proteins; it can readily donate one of its phosphate groups to adenosine diphosphate (ADP) to form adenosine triphosphate (ATP), an extremely important intermediate in the transfer of chemical energy in living systems.
GTP is the source of the guanosine found in RNA and deoxyguanosine triphosphate (dGTP) is the source of the deoxyguanosine in DNA, and thus guanine is intimately involved in the preservation and transfer of genetic information.
reference.allrefer.com /encyclopedia/G/guanine.html   (317 words)

  
 Guanosine triphosphate(GTP)-binding proteins (G proteins) are involved in numerous intracellular events including ...
Guanosine triphosphate(GTP)-binding proteins (G proteins) are involved in numerous intracellular events including signal transduction, cellular proliferation, intracellular vesicle trafficking and cytoskeletal control.
Guanosine triphosphate (GTP)-binding proteins (G proteins) are involved in numerous intracellular events including signal transduction, cellular proliferation, intracellular vesicle trafficking and cytoskeletal control.
Upon activation, GDP is released and is replaced by GTP, rendering the G protein active and capable of interacting with effector molecules, such as ion channels and enzymes, to stimulate further biological activity.
www.chem.umn.edu /studsem/abstract9899/Kale52599/abstract.html   (603 words)

  
 Guanosine triphosphate -- Facts, Info, and Encyclopedia article   (Site not responding. Last check: )
Guanosine triphosphate -- Facts, Info, and Encyclopedia article
Guanosine triphosphate (GTP) is also known as guanosine-5'-triphosphate, G3P, and 9-ß-D-ribofuranosylguanine-5'-triphosphate (or, equivalently, 9-ß-D-ribofuranosyl-2-amino-6-oxo-purine-5'-triphosphate).
This is tantamount to the generation of one molecule of (A nucleotide derived from adenosine that occurs in muscle tissue; the major source of energy for cellular reactions) ATP since GTP is readilty converted to ATP.
www.absoluteastronomy.com /encyclopedia/g/gu/guanosine_triphosphate.htm   (129 words)

  
 Purine nucleoside 5'-phosphate (mono, di or tri) 3'(2')-diphosphates and processes for their preparation - Patent ...
As is well known, adenosine tetraphosphate (ppppA), guanosine tetraphosphate (ppGpp) and Guanosine pentaphosphate (pppGpp) are distributed in nature, especially in microorganisms and animals, as unusual nucleoside phosphates.
The ppGpp and pppGpp are particularly being watched with keen interest in the regulation of protein and ribonucleic acid syntheses in E. coli, and it is expected that they have an important role in glycolysis, lipid synthesis, energy metabolism and phosphorylation of various organisms.
4 and 5 are NMR spectra of guanosine 5'-diphosphate 3'-diphosphate and inosine 5'-triphosphate 3'-diphosphate respectively.
www.freepatentsonline.com /4141972.html   (6587 words)

  
 Prolonged Depletion of Guanosine Triphosphate Induces Death of Insulin-Secreting Cells by Apoptosis -- Li et al. 139 ...
Prolonged Depletion of Guanosine Triphosphate Induces Death of Insulin-Secreting Cells by Apoptosis -- Li et al.
Prolonged Depletion of Guanosine Triphosphate Induces Death of Insulin-Secreting Cells by Apoptosis
Guanosine or adenosine was also included (in experiments using 1 µg/ml MPA for 48 h).
endo.endojournals.org /cgi/content/full/139/9/3752   (7341 words)

  
 Why? Vocabulary
Nitric oxide activates the enzyme _____ to convert guanosine triphosphate (GTP) to cyclic guanosine monophosphate (cGMP).
Nitric oxide activates the enzyme soluble guanylyl cyclase (sGC) to convert guanosine triphosphate (GTP) to _____.
Cyclic Guanosine Monophosphate is a _____ of blood vessels.
ideaplace.org /Tester/TesterVL.cgi?fd=why&tf=NOAndcGMP.FB   (148 words)

  
 A Structural Basis for the Inhibition of the NS5 Dengue Virus mRNA 2'-O-Methyltransferase Domain by Ribavirin ...
The guanosine analogue ribavirin is a broad spectrum antiviral
ribavirin is a guanosine analogue and a weak inhibitor of flavivirus
Ribavirin triphosphate is represented in ball-and-stick form and colored according to atom type.
www.jbc.org /cgi/content/full/279/34/35638   (3254 words)

  
 Guanine - EvoWiki   (Site not responding. Last check: )
When guanine pairs with a ribose sugar it forms the nucleoside guanosine.
Guanosine phosphate (GMP) - a constituent of nucleic acids
Guanosine diphosphate (GDP) and guanosine triphosphate (GTP) - used as energy carriers in some metabolic reactions (similar to Adenosine triphosphate)
wiki.cotch.net /index.php/Guanine   (146 words)

  
 AEGiS-08CROI: Mechanistic studies of dioxolane guanosine 5 -triphosphate: implications for efficacy, lack of cross- ...
Background: DAPD, a prodrug of dioxolane guanosine (DXG), is a nucleoside analog currently in Phase I/II clinical trials for the treatment of HIV infection.
AEGiS-08CROI: Mechanistic studies of dioxolane guanosine 5 -triphosphate: implications for efficacy, lack of cross- resistance and selectivity of DAPD.
Mechanistic studies of dioxolane guanosine 5 -triphosphate: implications for efficacy, lack of cross- resistance and selectivity of DAPD.
www.aegis.com /conferences/CROI/2001/306.html   (518 words)

  
 MSN Encarta - Search Results - guanosine triphosphate
Adenosine Triphosphate (ATP), molecule found in all living organisms that is the main immediate source of usable energy for the activities of the...
Both were known to play a role in releasing glucose (sugar) in the...
Search for books about your topic, "guanosine triphosphate"
encarta.msn.com /guanosine+triphosphate.html   (116 words)

  
 Guanosine triphosphate acts as a cofactor to promote assembly of initial P-element transposase-DNA synaptic complexes ...   (Site not responding. Last check: )
Guanosine triphosphate acts as a cofactor to promote assembly of initial P-element transposase-DNA synaptic complexes -- Tang et al.
Articles by Tang, M. Articles by Rio, D. Guanosine triphosphate acts as a cofactor to promote assembly of initial P-element transposase–DNA synaptic complexes
P-element transposase uses guanosine triphosphate (GTP) as a
www.genesdev.org /cgi/content/abstract/19/12/1422   (206 words)

  
 Figures
When not stimulated, the α subunit is coupled to guanosine diphosphate (GDP).
Activation of the G-protein coupled receptor (R) by an agonist (A) results in dissociation of the heterotrimeric G-protein into an α subunit coupled to guanosine triphosphate (GTP) and a βγ dimer.
The intrinsic adenosine triphosphate (ATP)-ase activity of the α subunit leads to restoration of the α-GDP complex, which has high affinity for the nonactivated receptor and the βγ subunits.
www.medscape.com /content/2003/00/46/32/463290/463290_fig.html   (522 words)

Try your search on: Qwika (all wikis)

Factbites
  About us   |   Why use us?   |   Reviews   |   Press   |   Contact us  
Copyright © 2005-2007 www.factbites.com Usage implies agreement with terms.