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	HLA Matching: Finding the Best Donor or Cord Blood Unit
		HLA are proteins -- or markers -- found on most cells in your body.
		You inherit half of your HLA markers from your mother and half from your father, so each brother and sister who has the same parents as you has a 25% chance of matching you.
		Because HLA types are inherited, your best chance of finding a suitable donor may be with someone of a similar racial or ethnic background.
	www.marrow.org /PATIENT/hla_matching.html (1145 words)

	MedlinePlus Medical Encyclopedia: HLA-B27 antigen
		HLA type B27 is associated with autoimmune diseases such as ankylosing spondylitis.
		The human leukocyte antigens (HLAs) are proteins present on the surface of all body cells that contain a nucleus, and are in especially high concentrations in white blood cells (leukocytes).
		HLA antigens are the major histocompatibility antigens for tissue recognition.
	www.nlm.nih.gov /medlineplus/ency/article/003551.htm (655 words)

	IBMT: FAQ - HLA Typing
		HLA typing is increasingly done using DNA techniques and can take several days to complete.
		Even in cases where the patient's HLA type is quite common, it can take a minimum of 4 to 6 weeks to obtain the donor's marrow.
		In some instances, the HLA type of the patient may be so unique that finding a matched unrelated donor is impossible.
	www.ibmtindy.com /faq/hla-typing.htm (495 words)

	HLA typing and Celiac Disease
		HLA stands for Human Leukocyte Antigen which are certain molecules found on the surface of cells.
		Which HLA molecules an individual manufactures is determined by the gene-variants the individual has inherited from his or her parents.
		It is important to remember that the very same HLA molecules that present gluten fragments also are very efficient in presenting fragments of virus and bacteria and are thus of great importance for the body to survive from various infections.
	www.enabling.org /ia/celiac/cel-hla.html (3726 words)

	Genomics\|HuGENet\|e-Journal\|Abstract\|SARS Severity & HLA Class I Alleles
		Gene product/function: HLA class I molecules (comprised of HLA-A, HLA-B, and HLA-C) present antigens on the surfaces of infected cells, thereby allowing cytotoxic T cells to bind and initiate the adaptive immune response [1].
		HLA alleles and genotypes have a marked degree of polymorphism at the population level and are implicated in the susceptibility, severity, and transmission of various infectious diseases [3].
		Gene product/function: HLA class II molecules (comprised of HLA-DR, HLA-DQ, and HLA-DP) present antigen on the surfaces of specific antigen-presenting cells to stimulate helper T cell activity for the cytotoxic T cell response and for the humoral immune response [1].
	www.cdc.gov /genomics/hugenet/ejournal/HLAabst.htm (1045 words)

	Patients Guide to HLA
		HLA stands for “Human Leukocyte Antigen.” These are protein molecules that we inherit from our parents. We currently know about nearly 600 different HLA molecules. Your HLA type must be determined before you have a stem cell transplant, which is done by taking a blood sample.
		The HLA “match” is the number of HLA molecules that any two people have in common. HLA matching is usually based on six HLA molecules. The more molecules two people share, the better the match.
		When two individuals share the same HLA type, they are said to be a good match. That is, their immune systems will not see each other as “foreign” and are less likely to attack each other.
	www.cityofhope.org /HLA/HLAPatientsGuide.htm (472 words)

	HLA-B - Genetics Home Reference
		The HLA complex helps the immune system distinguish the body's own proteins from proteins made by foreign invaders such as viruses and bacteria.
		HLA is the human version of the major histocompatibility complex (MHC), a gene family that occurs in many species.
		In humans, the HLA-B gene and two related genes, HLA-A and HLA-C, are the major genes in MHC class I. MHC class I genes provide instructions for making proteins that are present on the surface of almost all cells.
	ghr.nlm.nih.gov /gene=hlab (1115 words)

	HLA: The High Level Assembly Programming Language \| Linux Journal
		In HLA, I wanted to create a language with high level control structures and declarations that made it possible for someone familiar with an imperative language like Pascal or C/C++ to get their first HLA programming running in a matter of minutes (or, at worst, a matter of hours).
		HLA Standard Reference Manual for quite awhile before he or she begins to write the first HLA program.
		For those interested in learning more about HLA and the Art of Assembly Language programming, Yahoo Groups offers aoaprogramming, which, as the Web site states, is a "forum for those interested in learning and working with Randall Hyde's HLA assembler." At the time of this writing, aoaprogramming had over 1,089 members.
	www.linuxjournal.com /article/8408 (1758 words)

	Timothy Hla Faculty Member at the UConn Health Center Graduate School
		Research in Dr. Hla's laboratory is focused on the molecular mechanisms of angiogenesis, also known as new blood vessel formation.
		Angiogenesis is important in physiological events such as wound healing as well as in pathological conditions such as solid tumor growth and rheumatoid arthritis.
		Chae SS, Paik JH, Furneaux H, Hla T. Requirement for sphingosine 1-phosphate receptor-1 in tumor angiogenesis demonstrated by in vivo RNA interference.
	grad.uchc.edu /phdfaculty/hla.html (796 words)

	Northern California's Comprehensive Thalassemia Center at at Children's Hospital Oakland
		HLA typing is therefore very important in order to find a donor and recipient whose cells most closely match.
		Because HLA types are genetically determined, the best chance for a match is a donor who is genetically related to the recipient.
		An individual's HLA type is inherited from his or her parents at the time of conception.
	www.thalassemia.com /hla.html (316 words)

	Human leukocyte antigen - Wikipedia, the free encyclopedia
		Besides functional HLA antigens, there are two additional HLA antigens in humans, HLA-DM and HLA-DO, which are important in loading the antigenic peptides generated from pathogens onto the HLA molecules of antigen-presenting cell.
		HLA types are inherited, and some of them are connected with autoimmune disorders and other diseases.
		HLA antibodies are typically not naturally occurring, with few exceptions are formed as a result of an immunologic challenge of a foreign material containing non-self HLAs via blood transfusion, pregnancy (paternally-inherited antigens), or organ or tissue transplant.
	en.wikipedia.org /wiki/Human_leukocyte_antigen (2012 words)

	HLA Diversity/Anthropology
		The goal of the Diversity/Anthropology Component is to determine HLA class I and class II allele and haplotype frequencies in various human populations.
		In a clinical context, a knowledge of the allele frequency distributions in various populations is critical to the strategy of establishing and searching bone marrow donor registries as well as in studies of HLA-associated disease susceptibility.
		There may be labs and investigators outside the HLA field who would like to collaborate with the Workshop in the study of HLA diversity of their samples.
	www.ihwg.org /components/diversr.htm (765 words)

	eMedicine - HLA-B27 Syndromes : Article by A Luisa Di Lorenzo, MB, BCh
		In ophthalmology, HLA associations are strongest in diseases of the uvea.
		An HLA disease association is defined as a statistically increased frequency of the HLA haplotype in individuals with the disease compared to the frequency in individuals without the disease.
		The HLA system is genetically encoded in humans by the major histocompatibility complex (MHC), which is found on chromosome 6, and plays a determining role in immunity and in self-recognition in virtually all cells and tissues, with the exception of erythrocytes.
	www.emedicine.com /oph/topic721.htm (4945 words)

	Identification of Antigenic Epitopes on Human Allergens: Studies with HLA Transgenic Mice
		HLA tg mice express intact HLA molecules on cells of the lymphoid system and respond to several protein, peptide, and parasitic antigens (Abraham and David 2000; Geluk et al.
		This study demonstrated that the expression of HLA class II molecules in normal lung tissue in tg mice is similar to that in humans (Chapoval et al.
		Thus, HLA class II transgenic mice offer the opportunity to investigate the role of distinct HLA molecules in allergen sensitivity and may be useful for devising new immune based therapies for allergic asthma.
	www.ehponline.org /members/2003/5706/5706.html (4930 words)

	HON Allergy Glossary Human Leukocyte Antigen
		Thought that people with certain types of HLA antigens are more likely to develop insulin-dependent diabetes.
		Patients and potential donors have their white blood cells tested for three antigens - HLA-A, -B and -DR. Each individual has two sets of these antigens, one set inherited from each parent.
		For this reason, it is much more likely for a brother or sister to match the patient than an unrelated individual, and much more likely for persons of the same racial and ethnic backgrounds to match each other.
	www.hon.ch /Library/Theme/Allergy/Glossary/hla.html (126 words)

	Welcome to Health Law Advocates - Health Law Advocates, Inc.
		HLA is affiliated with Health Care For All, the premier health advocacy organization in Massachusetts.
		HLA is the only non-profit law firm in the country affiliated with a grass roots organization and dedicated solely to ensuring access to health care for society’s most vulnerable members.
		Viewing such information or contacting HLA via electronic means does not create an attorney-client relationship between you and HLA.
	www.hla-inc.org (253 words)

	Pitch - HLA for Beginners (Site not responding. Last check: 2007-11-03)
		HLA (High-Level Architecture) is a standard for connecting several computer-based simulation systems so that they can run together and exchange information.
		One of the reasons that HLA is so flexible is that you can develop a FOM to meet the needs of your particular federation.
		There are currently two standards, HLA 1.3, the first standard (developed by US Department of Defence) and the new, improved, IEEE 1516 standard for HLA.
	www.pitch.se /hla/hlaforbeginners.asp (799 words)

	HLA in the News - Health Law Advocates, Inc.
		Therefore, on November 23, 2005, HLA and MLRI issued a demand upon the state for immediate implementation and threatened suit in the event of a failure to comply.
		The resulting lawsuit was filed jointly by HLA and MLRI on December 6, 2005 and on the eve of the court hearing scheduled for December 16, 2005, the state agreed to implement the benefits in issue by January 15, 2006.
		HLA’s Eating Disorder Work Group wrote an educational piece for the media on eating disorders in connection with the tragic case of Ms.
	www.hla-inc.org /inside.php?target=12 (1225 words)

	HLA, a height field image generator
		John Beale's Hf-Lab, HLA is for creating 'fractal forgery' landscape/skyscape/map "height fields" by spectral synthesis (Fourier-transforming noise, Reference: The Science of Fractal Images, Peitgen, Saupe eds.), and various other algorithms, mainly for use with
		HLA is mainly meant to fit my own needs and there might be peculiarities in its use which are not documented.
		HLA is distributed without warranty under the terms of the GNU General Public License
	www.geocities.com /hacad/hla (219 words)

	Primary association of HLA-B51 with Behcet's disease in Ireland -- Kilmartin et al. 81 (8): 649 -- British Journal of ...
		HLA typing was carried out by the National Tissue Typing Reference Laboratory of the Blood Transfusion Service Board.
		HLA haplotypes and all siblings possessing the HLA-B51
		HLA antigens and adamantiades-Behçet's disease (A-BD) in Greeks.
	bjo.bmjjournals.com /cgi/content/full/81/8/649 (2730 words)

	HLA Matching
		Therefore, an increasing number of couples with a child affected by such a disease are requesting preimplantation HLA matching to conceive a healthy child who would became a future donor of HSC, to provide radical treatment for the existing affected recipient sibling.
		This procedure involves a minisequencing-based genotyping of HLA regions A, B, C, and DRB combined with mutation analysis of the gene regions involved by mutation.
		This approach permits HLA genotyping in preimplantation embryos combined with analysis of single gene disorders, by use of a flexible protocol that can be applied to a wide spectrum of different HLA allele combinations, reducing notably time needed for preclinical set-up of each PGD case.
	www.reproductivegenetics.com /hla_matching.html (798 words)

	LabCorp Identity Testing Services - HLA Molecular Typing
		The informative regions of the DNA are replicated using the polymerase chain reaction (PCR).
		LabCorp uses approximately 100 probes to analyze the DNA coding for the HLA-A and -B loci.
		These methods are similar to those employed for Class I HLA typing where PCR is used to amplify the DNA of interest (DRß or DQß gene sequences) and probes determine what sequences are present in the amplified DNA.
	www.labcorp.com /paternity/hla_testing_services/transplantation/pcr_methodology/index.html (452 words)

	HLA Series
		The HLA system consists of the main three-way cabinet, the HLA-4895, and the matching HLA-4897A subwoofer.
		In the HLA Series, every detail of a tour sound loudspeaker system has been carefully rethought and re-engineered to maximize output and control while reducing weight, truck space and setup time.
		When flying the HLA cabinets, the SpaceFrame distributes the weight throughout the entire cabinet rather than concentrating stress at mounting points.
	www.jblpro.com /pages/tour/HLA/hlaserie.htm (581 words)

	HLA Testing
		Human Leukocyte Antigens (HLA) are found in your blood and are the primary source of immuno-rejection during an organ transplant.
		This class of markers is characterized by numerous genetic mutations, many of which directly affect the immune response during an organ transplant.
		HLA Class I Single Antigen Antibody, Group 1 Human
	www.luminexcorp.com /applications/hla_testing.html (130 words)

	Pitch - HLA (Site not responding. Last check: 2007-11-03)
		The High Level Architecture (HLA) for simulations is an architecture to support interoperability and reuse all types of models and simulations.
		Definitions of the interface functions between the runtime infrastructure and the simulations participating in a HLA federation.
		The HLA Object Model Template (OMT) defines a structured and consistent way to document HLA-relevant information about classes of simulations or federation objects and their attributes and interactions.
	www.pitch.se /hla/default.asp (273 words)

	Unravelling an HLA-DR Association in Childhood Acute Lymphoblastic Leukemia -- Dorak et al. 94 (2): 694 -- Blood
		The supertypic specificity HLA-DR53 is encoded by the HLA-DRB4 locus in the HLA class II region.
		HLA class II supertypes are not allelic with each other and some haplotypes even lack a supertype.
		Svejgaard A, Ryder LP: HLA and disease associations: Detecting the strongest association.
	www.bloodjournal.org /cgi/content/full/94/2/694 (4958 words)

	Anthony Nolan Research Institute - HLA Informatics Group
		It is now established procedure for authors to submit the sequences directly to the HLA Sequence Database for checking and assignment of an official name prior to publication, this avoids the problems associated with renaming published sequences and the confusion of multiple names for the same sequence.
		The work on the HLA database is done in collaboration with Julia Bodmer (ICRF), James Robinson previously of the ICRF now at the ANRI and Peter Parham of Stanford University.
		In collaboration with the routine HLA typing laboratory we are currently analysing data from British Askenazi Jewish and Afro-Caribbean populations.
	www.anthonynolan.org.uk /HIG (913 words)

	HLA, Inc. -- About HLA
		HLA has performed these services with clients throughout the Southeast:
		Routinely assisting with site selection and feasibility studies, we provide aerial photography, wetland interpretation and topography and boundary surveying Once your site is determined appropriate, we provide site engineering, utility planning, and we work closely with other consultants to accomplish the integrated aspects of the project, including architecture and associated value engineering.
		From new residential communities, parks and suburban mixed-use centers to Class A industrial parks and corporate headquarters, we offer reliable, all-inclusive design and developmental consulting.
	www.hlainc.com /AboutHLA.htm (303 words)

	HIV Report May 2002 - HLA B57 and Abacavir Hypersensitivity (Site not responding. Last check: 2007-11-03)
		One interesting conclusion of this article is that HLA B5701 is probably not the causative gene, but is linked to another genetic region encoding a family of human heat shock proteins (HSP), which is the more likely culprit.
		SNP and HLA B57 genes are linked, which suggests that this is probably a secondary, rather than a primary association.
		HLA B5701 should not be used as a diagnostic test for abacavir hypersensitivity, since the majority of U.S. patients (especially non-Caucasians) who have the syndrome will not have the gene.
	www.hopkins-aids.edu /publications/report/may02_2.html (983 words)

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