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| | Jonathan P. Arm |
 | | Arm's research interests are the role of phospholipase A2 in innate immune responses; and a novel family of immunoregulatory receptors, the human leukocyte immunoglobulin-like receptors (LIRs). |
 | | Phospholipase A2 and innate immune responses Ð Phospholipase A2 (PLA2) releases arachidonic acid from the sn-2 position of cell membrane phospholipids for metabolism by 5-lipoxygenase to leukotrienes (LT) or by one of the isoforms of cyclooxygenase (COX) to prostaglandins. |
 | | Fujishima H, Sanchez Mejia, R O, Bingham C O, III, Lam B K, Sapirstein A, Bonventre J V, Austen K F, Arm J P. Cytosolic phospholipase A2 is essential for both the immediate and the delayed phases of eicosanoid generation in mouse bone marrow-derived mast cells. |
| www.hms.harvard.edu /dms/immunology/fac/Arm.html (916 words) |
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