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| | Octahydro-1,3,5,7-tetranitro-1,3,5,7-tetr... (HMX) (CASRN 2691-41-0), IRIS, Environmental Protection Agency |
 | | HMX was incorporated into the daily diet of 20 rats/sex/dose for 13 weeks at the following levels: 0, 50, 150, 450, 1350, and 4000 mg/kg/day for males and 0, 50, 115, 270, 620, and 1500 mg/kg/day for females. |
 | | However, the concentrations assayed were low due to limited solubility of HMX in water, and the authors conceded that the findings may represent false negatives. |
 | | The Saccharomyces cerevisiae mitotic gene conversion assay with untreated and with postchlorinated or ozonated samples of saturated HMX was also negative, but the limited solubility of HMX lowers confidence in the studies. |
| www.epa.gov /iris/subst/0311.htm (1974 words) |
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