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Topic: Haemophilia

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Haemophilia is a rare blood disorder caused by an inherited gene.
Haemophilia is a blood clotting disorder in which one of the essential clotting factors is deficient.
When the mother carries the haemophilia gene and the father is unaffected there will be a 50 per cent chance at each birth that their daughter may carry the haemophilia gene or that their son may have haemophilia.
www.healthinsite.gov.au /topics/Haemophilia   (545 words)

 NNHF - About Haemophilia
Haemophilia is a congenital bleeding disorder that affects males.
Those with haemophilia B have similar problems with Factor IX (FIX).  Haemophilia is characterised as "severe" when the activity of the affected clotting factor (FVIII or FIX) is less than 1% of normal.
Haemophilia is termed "mild" when the relevant clotting factor activity is greater than 5%, but less than normal and "moderate" when clotting factor activity is between 1% and 5% of normal.  Approximately 50% of haemophilia patients have severe disease and can require treatment for bleeding several times per month.
www.nnhf.org /documents/article_page/document/abouthaemophilia.asp   (294 words)

  Victoria of the United Kingdom - Wikipedia, the free encyclopedia
Victoria was the first known carrier of haemophilia in the royal line, but it is unclear how she acquired it.
Victoria herself did not suffer from the disease, however, she passed it on to Princess Alice and Princess Beatrice as carriers, and Prince Leopold was affected with the disease.
The most famous haemophilia victim among her descendants was her great-grandson, Alexei, Tsarevich of Russia.
en.wikipedia.org /wiki/Queen_Victoria   (6678 words)

 HAEMOPHILIA, VON WILLEBRAND SYNDROME and other coagulation defects: Contact a Family - for families with disabled ...
Haemophilia occurs in about 1 in 10,000 of the population in the UK, with haemophilia A (six thousand patients) being five times as frequent as haemophilia B (one thousand two hundred and fifty patients).
These are generally milder than haemophilia and are usually autosomal recessive, only being fully expressed in the homozygous (having two identical forms of the gene, one inherited from each parent) or doubly heterozygous (having two different forms of a particular gene, one inherited from each parent) state.
Haemophilia A and B are sex (X) linked and it is usually possible to determine the causative genetic abnormality but new spontaneous mutations are not uncommon.
www.cafamily.org.uk /Direct/h18.html   (1296 words)

 South African Haemophilia Foundation
These web pages are part of our commitment to promote the welfare of all persons with haemophilia and similar conditions in
We hope it will help provide a better understanding of this inherited, lifelong bleeding disorder which affects males almost exclusively.
Haemophilia Foundation by e-mail, or write to us at
www.haemophilia.org.za   (66 words)

 Science Museum | Your genes | Haemophilia
Haemophilia is a disorder that affects blood clotting and it mainly affects boys.
People with haemophilia bruise easily and bleed for longer if they injure themselves.
The main problem for people with haemophilia is bleeding inside the body, especially around joints.
www.sciencemuseum.org.uk /exhibitions/genes/212.asp   (78 words)

 Bayer Biological Products EU - About Haemophilia
Individuals with haemophilia have deficient or defective coagulation (or clotting) proteins in their bloodstream, which causes the body to bleed uncontrollably from even minor injuries.
Haemophilia is an X-linked (or sex linked) inherited disorder that can be passed along by females who carry a recessive gene for the disease.
Haemophilia, a potentially life-threatening disease, is categorized as mild, moderate, or severe, depending on the amount of bleeding that results from minor injuries.
www.biological.com /abouthaemophilia.cfm   (334 words)

The Haemophilia Society is working for people with haemophilia, von Willebrand's or a related bleeding disorder and their families to secure the best possible care, treatment and support.
The Society was established in 1950 and is the national charity in the UK of and for people with haemophilia, von Willebrand's and related bleeding disorders.
We also provide services for people with haemophilia affected by HIV and hepatitis C.The Haemophilia Society has a strict confidentiality policy and is committed to equal opportunities.
www.haemophilia.org.uk   (207 words)

 Haemophilia B : BPL (Bio Products Laboratory)
Haemophilia B is due to a deficiency of Factor IX.
Haemophilia - Issues and options for women who are carriers.
A comprehensive introduction for people with haemophilia and von Willebrand disease covering many of the important aspects of living with a bleeding disorder.
www.bpl.co.uk /public/therapy_areas/coagulation/haemophilia_b.asp   (333 words)

 Haemophilia, HIV, HCV Blood Factor Lawsuits: 2007 Update
Persons with haemophilia in the United States, Latin America, Europe, Asia, the Middle East and Africa were infected with contaminated blood products.
Lieff Cabraser is representing clients from around the world in lawsuits filed in U.S. courts against American blood companies that sold in the U.S. and exported contaminated blood worldwide.
Lieff Cabraser Heimann and Bernstein, LLP, represents persons with haemophilia worldwide, or their survivors and estates, who received blood products manufactured by American companies in the early to mid-1980's.
www.haemophilia-litigation.com   (812 words)

 Stem Cell Research Blog » Significant Progress in Haemophilia Treatment using Gene Therapy
Impressive progress has been made in the treatment of haemophilia using gene therapy.
Professor Katherine High, a leading researcher from Philadelphia USA, is examining the obstacles to successful gene therapy in human patients with haemophilia.
Gene therapy has already been used to successfully treat haemophilia in mice and dogs.
stemcell.taragana.net /archive/gene-therapy-treatment-of-haemophilia   (268 words)

 Promising Therapies For Haemophilia & Heart Disease
ScienceDaily (Aug. 11, 2005) — Haemophilia is a hereditary blood disease, primarily affecting males, where the blood fails to clot causing potentially life-threatening 'bleeds'.
About one in 6000 Australian males is born with haemophilia in severe, moderate or mild form.
Researchers Successfully Test New Drug To Treat Acquired Haemophilia (Jul. 21, 2006) — Researchers at the Universitat Autonoma de Barcelona Teaching Unit at Vall d'Hebron Hospital have developed a therapy to treat acquired haemophilia A. The therapy is based on the use of cyclosporin,...
www.sciencedaily.com /releases/2005/08/050810135052.htm   (775 words)

Haemophilia A (FVIII) Haemophilia B (FIX) Other Factor Desficiencies Von Willebrands Female Specific Disorders FAQ's News Bloodline Treatment Centres Member Services
The Haemophilia Foundation of New Zealand Inc. (HFNZ) was established in 1958 to serve the needs of people with haemophilia and other related bleeding disorders.
HFNZ is dedicated to improving the lives of people with haemophilia and related bleeding disorders; but we can not do it alone.
www.haemophilia.org.nz   (329 words)

 Haemophilia Foundation Australia // Welcome to Haemophilia Foundation
Haemophilia Foundation Australia // Welcome to Haemophilia Foundation
Haemophilia Foundation Australia (HFA) represents people with haemophilia, von Willebrand disorder and other related bleeding disorders and their families.
As a National Member Organisation of the World Federation of Hemophilia, HFA participates in international efforts to improve access to care and treatment for people with bleeding disorders around the world.
www.haemophilia.org.au   (78 words)

 Haemophilia Foundation Australia // Knowledge   (Site not responding. Last check: )
The Student with Haemophilia (Haemophilia Foundation Australia, revised 1995)
Chapter 2 - Introducing haemophilia (Haemophilia Foundation Australia 2004) (Natashia Coco, 209Kb)
Haemophilia, Arthritis and Your Student -a guide for teachers (Haemophilia Foundation Australia, 1999)
www.haemophilia.org.au /knowledge/index.php?cid=47   (783 words)

 Haemostasis Forum
This is a web site dedicated to supplying information on haemophilia to medical and health care professionals, providing an excellent opportunity to interact with worldwide specialists in the field of haematology.
Each month the contents of these pages are updated and reviewed by a panel of independent haemophilia specialists.
This forum is supported by an educational grant from Novo Nordisk A/S. If you would like to access this site, please click on 'Register Now' and submit your details.
www.haemophilia-forum.org   (93 words)

 Haemophilia - Journal Information
Dose effect and efficacy of rFVIIa in the treatment of haemophilia patients with inhibitors: analysis from the Hemophilia and Thrombosis Research Society Registry
Young G, McDaniel M, Nugent DJ Prophylactic recombinant factor VIIa in haemophilia patients with inhibitors
Rituximab for autoimmune haemophilia: a proposed treatment algorithm
www.blackwellpublishing.com /journals/hae   (237 words)

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