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Topic: Hair cell


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In the News (Mon 13 Feb 12)

  
  Hair cell - Wikipedia, the free encyclopedia
Hair cells are the sensory cells of both the auditory system and the vestibular system in all vertebrates.
In mammals, the auditory hair cells are located within the organ of Corti on a thin basilar membrane in the cochlea of the inner ear.
The inner hair cells transform the sound vibrations in the fluids of the cochlea into electrical signals that are then relayed via the auditory nerve to the auditory brainstem and to the auditory cortex.
en.wikipedia.org /wiki/Hair_cells   (762 words)

  
 Hair cell
Hair cells are the sensory cells of the auditory system that are found within the cochlea's organ of Corti.
Modern research has shown that outer hair cells are motile and responsible for stimulus compression and amplification, while the inner hair cells are responsible for transforming the input sound stimulus into a series of action potentials that are relayed via the auditory nerve to the brainstem and auditory cortex.
The influx of positive ions increases the receptor potential of the cell, which in turn, triggers the release of neurotransmitter at the basal end of the cell, via the opening of voltage gated calcium channels.
www.xasa.com /wiki/en/wikipedia/h/ha/hair_cell.html   (208 words)

  
 Lovett: Background information on hair cell regeneration
Hair cells in the mammalian ear are formed during a limited period of embryonic development, and can be lost later in life as a consequence of acoustic trauma, treatment with ototoxic drugs, infections or autoimmune pathologies, or as part of the aging process.
Significant levels of cell death and cell proliferation are observed in the undamaged chick utricle, suggesting that a sizable fraction of hair cells in that organ are either in an immature state or are near-death.
Hair cells in the mature vestibular organs appear to die spontaneously, and are then replaced by new cells that arise from the ongoing proliferation of epithelial supporting cells.
hg.wustl.edu /lovett/hair_cell_info.html   (857 words)

  
 Hair Cell Regeneration
We hope that by understanding where hair cells come from in the embryo and how their progenitors are controlled at the molecular level, we will better understand the reasons for the lack of regeneration in humans and, ultimately, discover ways of curing hair cell loss.
The first is to demonstrate the presence of hair cell precursors in the adult Organ of Corti,and to attempt to stimulate them to re-enter the cell cycle to generate differentiated hair cells.
The three rows of stereocilia which protrude from the underlying hair cells are seen are on the left and the single row of stereocillia corresponding to the inner hair cells are on the right.
www.hei.org /research/cmb/cellgrow/haircellchall.html   (895 words)

  
 Hair Cell Regeneration   (Site not responding. Last check: 2007-10-23)
Nerve deafness results from the loss of hair cells, sensory cells in the inner ear with bundles of hairlike projections that bend in response to sound waves.
The cells convert this mechanical force into electrical impulses that are carried by the auditory nerve to the brain.
Hair cells, located in the hearing and balance organs of the inner ear, naturally regenerate after damage in many species of animals.
www.unc.edu /courses/2002spring/psyc/023/001/hair_cell.html   (726 words)

  
 Stem Cell Research in Mice Shows New Cochlear Hair Cell Growth - Tinnitus Information Center
Stem cell research in the United States remains at the center of controversy and was a hotly debated topic during the recent election.
Hair cell loss is caused by exposure to excessive noise, aging, genetic mutations, autoimmune disease, and ototoxic medications such as aminoglycoside antibiotics.
Adult stem cells are undifferentiated cells that are found in organ tissue and have the capacity to produce specialized cell types for that particular organ.
www.tinnitusformula.com /infocenter/articles/treatments/haircells.aspx   (771 words)

  
 How the Ear Works - Outer Hair Cell Is Pressurized
The outer hair cell has reinforced the membrane along the cylindrical part of the cell to prevent it from bursting and to maintain the cylindrical shape.
The shape of the outer hair cell is maintained by a pressurized fluid core that pushes against an elastic wall.
Outer hair cells are isolated from the organ of Corti and kept alive to record their electromotility while recording their movements on video.
www.bcm.edu /oto/research/cochlea/Volta/15.html   (801 words)

  
 Breakthrough in Hair Cell Regeneration
Healthy hair cells are vital to the ability to hear, but aging, infection, certain medications and exposure to loud noises can damage or destroy hair cells causing sensorineural hearing loss - a condition affecting over 30 million Americans.
Moving hair cells initiate electrical signals, which are picked up by auditory nerve fibers and carried to an area of the brain called the auditory cortex.
Cells that express Math1 are fated to become hair cells, while Math1 expression is inhibited in the remaining non-sensory cells," Raphael says.
www.hearinglossweb.com /Medical/cures/hair/brkthru.htm   (1093 words)

  
 ABL - Hair Cell Heterogeneity
The image on the left shows the large subnuclear ER and large mitochondria found in hair cells of hte striolar region of the utricle while the image at the right is from a hair cell in the extrastriolar region.
The striolar hair cells, which we refer to at "type-I like" is very similar to the amniote type I hair cell, while the cell to the right is typical of amniote type II hair cells.
These results also strongly support the argument that diversity in hair cell structure is probably related to the diversity of function found in even the earliest representations of the vertebrate ear See Lanford, Platt, and Popper (2000) and Fay and Popper (2000) for a discussion of the evolution of the ear and hair cells.
www.life.umd.edu /biology/popperlab/research/hcheterogeneity.htm   (454 words)

  
 Inner Ear Cell Structure and Function
The mechanism of cochlear amplification is based in the motile properties of auditory sensory cells known as outer hair cells (OHCs), which elongate and shorten in response to external stimuli.
Cell shape changes, in turn, entail loss of equilibrium between internal tensional forces, and its regulation must involve a mechanism able to compensate this imbalance.
“Structure of the Cortical Cytoskeleton in Mammalian Outer Hair Cells.” J.Cell Sci.
www.hei.org /research/cmb/cellstru/cellstru.htm   (1277 words)

  
 How the Ear Works - Outer Hair Cell Electromotility
Synaptic structures are found at the base of the hair cell and they are responsible for converting electrical energy into chemical energy by modulating the release of neurotransmitters that activate the 8th nerve fibers contacting the cell.
The top and the bottom of the outer hair cell perform functions that are common to all hair cells.
The elongated cylindrical portion of the outer hair cell is where electrical energy is converted into mechanical energy.
www.bcm.edu /oto/research/cochlea/Volta/14.html   (308 words)

  
 Outer Hair Cell - and more   (Site not responding. Last check: 2007-10-23)
Outer Hair Cell - Silvis, ill. - with a near-flawless round and a trophy to go with it, this was the kind of day sean o hair s father probably envisioned all those years he was pushing the teenager.
Newville hair stylist scott kelly hopes to reopen your hair station within a week at a new location in the newville plaza, 34 n.
Epiderma, the largest laser hair removal network in canada, has chosen the city of kingston to launch the first phase of its expansion into ontario where two more clinics are slated to open later this summer.
hair-7.627hair.com /Outer-Hair-Cell.html   (470 words)

  
 Single Hair Cell - and more   (Site not responding. Last check: 2007-10-23)
Single Hair Cell - British actress keira knightley suffered a hair nightmare when constant styling for a quick succession of roles damaged her locks beyond repair.
The budget proposed for next year is only a hair larger than the budget approved for this year.
their civil rights lawsuit is one of many legal challenges to the use of hair to test for drug use by police officers and private sector workers.
hair-8.627hair.com /Single-Hair-Cell.html   (515 words)

  
 Single Human Hair Cell - and more   (Site not responding. Last check: 2007-10-23)
Single Human Hair Cell - Cheshire police are trying to find the parents of a young boy who was found wandering the streets of warrington.
Oranjestad, aruba investigators said monday they will conduct dna tests on blond hair attached to duct tape that was found along aruba s coast to see whether it came from natalee holloway in a possible break to the 6-week-old mystery.
Hair guru kevin mancuso, who has styled everyone from renee zellweger to halle berry, will be at kiehl s in university village friday from 11 a.m.
hair-8.627hair.com /Single-Human-Hair-Cell.html   (467 words)

  
 Signals From a Hair Cell
The star of the performance, magnified many times under a high-powered microscope, was a sound-receptor cell from the ear of a bullfrog, called a hair cell because of the distinctive tuft of fine bristles sprouting from its top.
In humans and other mammals, hair cell bundles are arranged in four long, parallel columns on a gauzy strip of tissue called the basilar membrane.
The messages travel through auditory nerve fibers that run from the base of the hair cells to the center of the cochlea, and from there to the brain.
www.hhmi.org /senses/c110.html   (545 words)

  
 hair cell regeration
June 2005 - Now that scientists have discovered the gene that inhibits hair cell reproduction, the next hurdle is developing a way to control that gene.
The hair cells move in response to acoustic energy entering the ear, and stimulate the auditory nerve with information regarding the characteristics of the incoming sound.
With respect to the degree of hair cell regeneration or restoration, my gut feeling is that it will all depend on what type of hearing loss a person has to begin with.
www.hearinglossweb.com /Medical/cures/hair/hair.htm   (1635 words)

  
 1999; Hair cell loss and supporting cell rearrangement in the chick cochlea after gentamicin treatment
SEM and LM studies of damaged cochleae have led to the hypothesis that the dying hair cells were ejected up into the scala media and overlying tectorial membrane.
However, it has recently been proposed that the hair cells eject only their sensory bundles in response to aminoglycosides and that the remaining portion of the hair cell rebuilds a new bundle in order to regain its functional capacity.
However, the lost hair cells still labeled with the myosin VIIa antibody and were found to be trapped in the overlying tectorial membrane.
www.aro.org /archives/1999/505.html   (431 words)

  
 Current Lymphoma Research Mantle Cell... - Hair Loss Advisor
ANDREW ZELENETZ, MD: Mantle cell lymphoma is an entity that was recognized actually by Lennard, and in the Lennard classification it was actually the centrocytic lymphomas.
In fact, GI tract involvement is so common that with the confirmed diagnosis of mantle cell lymphoma we have been recommending an evaluation of the GI tract with upper GI endoscopy and colonoscopy.
The role of rituximab in the combination with chemotherapy is clearly intriguing and is currently the subject of investigation in regimens like that described by Czuczman in the Journal of Clinical Oncology for the treatment of low-grade lymphoma.
www.hairlossadvisor.com /hairlossadvisor/13151.htm   (1447 words)

  
 Arm Hair Cell - and more   (Site not responding. Last check: 2007-10-23)
Arm Hair Cell - The debate over the existence of sasquatch, aka bigfoot, an ape-like creature said to haunt the wilderness of western canada has entered the world of modern dna testing.
Talking to players on the practice green in cromwell, conn., it wasn t hard to figure out who d be moving on to the deutsche bank championship and who d be taking this week off.
La jolla spa md in california for laser treatments to remove all the hair from her pubic area.
hair-1.627hair.com /Arm-Hair-Cell.html   (422 words)

  
 hair cell - Search Results - MSN Encarta
Hair, collective term for slender, threadlike outgrowths of the epidermis of mammals, forming a characteristic body covering.
The skin is an organ of double-layered tissue stretched over the surface of the body and protecting it from drying or losing fluid, from harmful...
- sensory cell in ear: a sensory cell with fine projections resembling hairs, especially one in the inner ear that transmits information on sound or movement to the brain
ca.encarta.msn.com /hair_cell.html   (133 words)

  
 UMHS Press Release: Auditory Hair Cells
This image shows Math1 expression (orange stain) in cells in and around the sensory epithelium of the inner ear from a guinea pig after gene therapy.
This scanning electron microscope image of inner ear tissue after Math1 gene transfer shows a new hair cell growing in a part of the guinea pig's inner ear where hair cells do not normally develop.
While U-M scientists were able to grow new auditory hair cells in guinea pigs, it's impossible to say whether gene therapy would work the same way in people or whether it would be safe to use in people.
www.med.umich.edu /opm/newspage/2003/haircells.htm   (1260 words)

  
 Hair Cell Regeneration
Furthermore, hair cell regeneration won't help people with conductive losses such as are caused by middle ear infections or otosclerosis, nor will it help people with auditory nerve conditions such as acoustic neuromas.
Also, hair cell regeneration will not help people with hearing loss if their hearing loss is caused by the absence of certain genes that result in hearing loss even though adequate numbers of hair cells are present.
Later, pictures taken of regenerated hair cells show them as irregularly shaped and the stereocilia (the "hairs" of the hair cells) look like they were all hashed together-not beautifully arranged like before.
www.hearinglossweb.com /Medical/cures/hair/neil.htm   (1023 words)

  
 Analysis of Rat Vestibular Hair Cell Development and Regeneration Using Calretinin as an Early Marker -- Zheng and Gao ...
Hair cells are the primary receptors in the end organs of the inner ear cochlear and vestibular systems.
Duckert LG, Rubel EW (1990) Ultrastructural observations on regenerating hair cells in the chick basilar papilla.
Lambert PR (1994) Inner ear hair cell regeneration in a mammal: identification of a triggering factor.
www.jneurosci.org /cgi/content/full/17/21/8270   (7215 words)

  
 research
The broad objective of this research is to gain an integrated view of the development and proliferation of sensory hair cells of the inner ear by using multidisciplinary approaches that draw on techniques from biophysics, anatomy, tissue culture, and molecular biology.
A main goal of this research is to determine the developmental pattern of ion channel expression in hair cells and the sensory ganglion cells of the inner ear, with the ultimate goal of understanding the regulation of ion channels in developing auditory and vestibular organs.
Immunohistochemistical approaches are being used to study the differentiation of hair cells and sensory ganglion cell during development.
taipan.nmsu.edu /neurolab/research/research.html   (1190 words)

  
 Arm Hair Cell Sideview - and more   (Site not responding. Last check: 2007-10-23)
Arm Hair Cell Sideview - To hand over chest hair, leg hair and in some cases pubic hair to labs conducting nypd.Ap) -- the seven police officers swore they didn t use cocaine, yet their hair tested positive for the drug.
Arm Hair Cell Sideview - Conditioning time he received a paw-dicure consisting of a trim of his nails and the hair between the pads of his feet.La jolla spa md in california for laser treatments to remove all the hair from her pubic area.
Arm Hair Cell Sideview - Pittsburgh, pa (prweb) september 01, 2005 -- dr. dominic a.
www.hair617.com /Arm-Hair-Cell-Sideview.html   (368 words)

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