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Topic: Heliox

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	Heliox - Wikipedia, the free encyclopedia
		Heliox is a gas that is composed of a mixture of helium (He) and oxygen (O2).
		Heliox has been used in a medical context since the 1930s, and although the medical community adopted its use initially to alleviate the symptoms of upper airway obstruction, its range of medical uses has since expanded greatly, most of which are dependent on the low density of heliox.
		This is why Heliox is used in the alleviation of many medical conditions that involve a decrease in airway diameter (and consequently increased airway resistance), such as upper airway obstruction, asthma, chronic obstructive pulmonary disease (COPD), bronchiolitis and croup.
	en.wikipedia.org /wiki/Heliox (430 words)

	heliox in asthma I (Site not responding. Last check: 2007-10-22)
		Kass describes a rapid improvement in respiratory acidosis with the early use of heliox (in ventilated and in spontaneously breathing patients).
		Austan reports the successful use of heliox by a 28-year-old woman in status asthmaticus and respiratory acidemia who refused orotracheal intubation and mechanical ventilation in the emergency department.
		Heliox was administered with a nonrebreathing oxygen mask, and the respiratory acidemia was corrected with two hours.
	pedsccm.wustl.edu /All-Net/english/reading/heliox.html (366 words)

	Heliox May Be Useful in the Treatment of Acute RSV Bronchiolitis
		The beneficial effects of heliox are felt to be related to the lower density of helium, which preserves laminar flow at higher flow rates, decreasing work of breathing by decreasing resistance to airflow.
		Heliox administration requires use of a facemask, which may not be well tolerated by all infants.
		The study was not blinded, due to the use of a facemask with heliox, and changes in voice/cry related to helium.
	www.med.umich.edu /pediatrics/ebm/cats/heliox.htm (450 words)

	University of Chicago Hospitals: Long-abandoned treatment revived for severe asthma attacks
		Although the beneficial effects of HELIOX were studied more than 60 years ago, this is the first report of its use in treating children with asthma.
		Because HELIOX is about one-third as dense as air, it is thought to reduce the effort required to breathe through a narrowed airway.
		HELIOX has been standard therapy for severe asthmatics in the pediatric and adult emergency rooms at the University of Chicago for nearly five years.
	www.uchospitals.edu /news/1997/19970312-heliox.php (501 words)

	American Journal of Critical Care: Use of heliox to avoid intubation in a child with acute severe asthma and hypercapnia (Site not responding. Last check: 2007-10-22)
		Heliox is a mixture of helium and oxygen that reduces airway resistance.
		While preparations for intubation were being made, she was given heliox from a premixed H-cylinder (80% helium, 20% oxygen) via a nonrebreather mask at a rate of 10 L/min, as indicated by an oxygen flowmeter (actual flow, 18 L/min).
		Heliox is a unique therapy for acute asthma because it decreases airway resistance without changing the diameter of the airway.
	www.findarticles.com /p/articles/mi_m0NUB/is_1_12/ai_96695973 (1420 words)

	CHEST: Heliox for status asthmaticus? - Editorial (Site not responding. Last check: 2007-10-22)
		Heliox is a mixture of oxygen and helium that has a lower density and a higher viscosity than nitrogen-oxygen mixtures.
		Heliox should, therefore, promote the transformation of some areas of turbulent flow, as is thought to occur in the bronchioles of asthmatic patients, to laminar flow, thereby reducing the resistive-pressure work of breathing.
		Although Kress and colleagues (9) showed that heliox, when used to carry aerosols to the lungs of patients with acute asthma, improves their expiratory flow rates, no study has demonstrated improved outcomes (eg, disposition, length of stay, and intubation) when heliox is used as the aerosol carrier gas.
	www.findarticles.com /p/articles/mi_m0984/is_3_123/ai_99236169 (1198 words)

	JHBMC: Respiratory Infections (Site not responding. Last check: 2007-10-22)
		Heliox is a low-density gas mixture of 70 percent helium and 30 percent oxygen.
		Researchers in Spain wanted to see if heliox would benefit infants who were being treated for a lower respiratory tract infection that is attributable to respiratory syncytial virus, or RSV.
		Researchers feel heliox therapy should be considered an option for infants who suffer from a lower respiratory tract infection.
	www.jhbmc.jhu.edu /healthcarenews02/02011005.html (242 words)

	The BOC Group - Jun 12, BOC launches cylinder to aid asthma sufferers (Site not responding. Last check: 2007-10-22)
		Heliox 21, which is a mixture of 21 per cent oxygen and 79 per cent helium, has proved to be effective in treating symptoms associated with upper and lower airway obstruction.
		The new cylinder incorporates an integral valve with a Heliox BS 6582 Schraeder outlet connector and a six to 15 litre flow clickstop, which eliminates the need for an external regulator.
		An additional benefit of Heliox is that it may also increase the duration of the 'therapeutic window', allowing extra time for other medications to take effect.
	www.boc.com /news/article_538_12jun03.asp (487 words)

	ANNALS Aug2001: AVOIDING INTUBATION IN THE INJURED SUBGLOTTIS: THE ROLE OF HELIOX THERAPY (Site not responding. Last check: 2007-10-22)
		Heliox is a combination of helium and oxygen that produces less-dense gas exchange.
		Heliox is a relatively safe and reliable alternative to intubation of children with severe subglottic edema or injury.
		Heliox should be considered before intubation for selected children with subglottic inflammation and severe airway distress.
	www.annals.com /abs/annals825.htm (211 words)

	UKDivers Community Forums - Mixed Gases
		Heliox is a mixture of helium and oxygen used for very deep diving, usually to greater than 200 feet.
		Heliox is simply a mixture of Helium & Oxygen, with no Nitrogen, and is used primarily in the commercial diving industry and in most mixed gas rebreathers.
		In addition to the physiological factors associated with Heliox, as we are using high partial pressures of Helium we therefore have a far greater rate of absorption and elimination of Helium into and out of the tissues.
	www.ukdivers.com /forum/topic.asp?TOPIC_ID=55 (2212 words)

	Heliox To Treat Upper Respiratory Obstruction In Children (Site not responding. Last check: 2007-10-22)
		This was a retrospective study conducted on 42 pediatric patients to evaluate the efficiency of helium-oxygen mixtures in relieving upper airway obstruction in the pediatric population.
		Heliox treatment duration ranged from 15 minutes to 384 hours, with an overall mean of 29.1 hours, with responders averaging 36.4 hours (median 16.8 hours) and non responders averaging 9.5 hours (median 4.5 hours)
		This study suggests that in appropriately chosen patient populations, heliox is a useful adjunct therapy and the response rates are good.
	www.indegene.com /Ent/Jour/indJour_LARY_Sum_01-09-2001_1.asp (492 words)

	RESPIRATORY CARE PROGRAMS
		Heliox has been reported to reduce the work of breathing in pediatric patients with severe upper airway obstruction.
		Mixed with oxygen (heliox), the density of helium reduces the resistance factor in gas delivery.
		The amount of time that a Heliox tank will last is determined not by the flow that is set on the oxygen flowmeter but by the actual flow delivered to the patient.
	www.nemc.org /RespCare/Heliox.htm (1112 words)

	Heliox in Bronchiolitis (Site not responding. Last check: 2007-10-22)
		Heliox in Bronchiolitis: Report of a Case and Discussion
		It should be emphasised that one should use heliox cautiously.
		heliox is expensive, thus increasing cost of care.
	pedsccm.wustl.edu /FILE-CABINET/Pulmonary/heliox1.html (718 words)

	'Lighter than air' breathing more than doubles COPD patients' exercise endurance
		The study, "Effect of heliox on lung dynamic hyperinflation, dyspnea, and exercise endurance capacity in COPD patients," was conducted by Paolo Palange, Gabriele Valli, Paolo Onorati, Rosa Antonucci, Patrizia Paoletti, Alessia Rosato, Felice Manfredi, and Pietro Serra from Dipartmento di Medicina Clinica, Servizio di Fisiopatologia Respiratoria, Università "La Sapienza," Rome, Italy.
		The authors conclude that "heliox breathing, by reducing airflow limitations, lung dynamic hyperinflation and dyspnea sensation, is capable of improving high-intensity exercise endurance capacity in moderate to severe COPD patients." However, they note that "further studies are needed to verify the potential role of heliox supplementation during exercise rehabilitation programs in COPD patients."
		The study, "Effect of heliox on lung dynamic hyperinflation, dyspnea, and exercise endurance capacity in COPD patients," by Palange et al.
	www.eurekalert.org /pub_releases/2004-11/aps-ta112904.php (775 words)

	DiveNews.Com (Site not responding. Last check: 2007-10-22)
		Two separate studies were presented that showed promise in the use of heliox (gas mixture used for deep sea diving) to treat the symptoms of people suffering from asthma.
		Heliox replaces the nitrogen component of air with helium, resulting in a gas that is four times less dense than air.
		Professor Andrew Peacock of the British Thoracic Society added that it is their belief that this study shows that while it is known that heliox is of value to technical divers, it also has a role in aiding asthmatics during severe attacks.
	www.divenews.com /print.php?sid=3023 (265 words)

	Heliox Delivery with Noninvasive Positive Pressure Ventilation: A Laboratory Study (Site not responding. Last check: 2007-10-22)
		Heliox flows of 0, 5, 10, and 18 L/min and oxygen flows of 0 and 10 L/min were titrated into the system at either a proximal position near the lung model or a distal position near the ventilator (titration method).
		Heliox is a mixture of helium and oxygen.
		Heliox was first used by Barach in 1934 for patients with diseases characterized by partial airway obstruction.
	www.rcjournal.com /contents/03.01/03.01.0248.asp (676 words)

	AARC: 40/60 Heliox Beneficial in a Conventionally Ventilated Adult Asthmatic (Site not responding. Last check: 2007-10-22)
		Heliox is a low-density gas mixture, and inhalation reduces airway resistance and the pressure required to overcome that resistance, stated study author Jodette A. Brewer, RCP, RRT, Clinical Specialist at Sharp Memorial Hospital, San Diego, California.
		The case study documents the benefits of a 40/60 heliox concentration for the treatment of respiratory failure due to status asthmaticus in an intubated, mechanically ventilated adult asthmatic.
		It was noted that immediately after the 40/60 heliox was initiated, peak airway pressure dropped from 32 cmH2O to 20 cmH20, and an ABG drawn 85 minutes after initiation of heliox showed improvement of arterial pH to 7.40 mmHg and Co2 decreased to 37 mmHg.
	www.pslgroup.com /dg/20F446.htm (503 words)

	Trimix and heliox diving (Site not responding. Last check: 2007-10-22)
		Trimix is used in very deep dives instead of air to reduce the partial pressure of oxygen (to avoid oxygen toxicity) and nitrogen (to avoid nitrogen narcosis).
		Heliox is a mix of helium and oxygen ("heli" and "ox").
		Professor Elihu Thompson speculated that helium could be used instead of nitrogen to dilute the oxygen content of a breathing mix and thus reduce narcosis, but because of high prices of helium at that time, the idea was mainlu hypothetic.
	www.techdiver.ws /trimix_eng.shtml (935 words)

	All-Net \| estatus asmático (Site not responding. Last check: 2007-10-22)
		Heliox inhalation in status asthmaticus and respiratory acidemia: a brief report.
		Heliox improves pulsus paradoxus and peak expiratory flow in nonintubated patients with severe asthma.
		Heliox probablemente se mostrará útil en el estudio de los mecanismos de vuelo de vertebrados e insectos.
	pedsccm.wustl.edu /All-Net/spanish/reading/heliox.html (242 words)

	Heliox Therapy in Infants With Acute Bronchiolitis -- Martinón-Torres et al. 109 (1): 68 -- Pediatrics (Site not responding. Last check: 2007-10-22)
		Heliox in the treatment of airflow obstruction: a critical review of the literature.
		Heliox improves pulsus paradoxus and peak expiratory flow in nonitubated patients with severe asthma.
		Paret G Dekel B, Vardi A, Szeinberg A, Lotan D, Barzilay Z. Heliox in respiratory failure secondary to bronchiolitis: a new therapy.
	pediatrics.aappublications.org /cgi/content/full/109/1/68 (3121 words)

	Heliox for nonintubated acute asthma patients (Cochrane Review)
		Objectives: To determine the effect of the addition of heliox to standard medical care on the course of acute asthma, as measured by pulmonary function testing and clinical endpoints.
		Sensitivity analyses were performed on age (adults vs. children), different helium-oxygen mixtures (80/20, vs. 70/30 or 60/40), methodological quality (Jadad score >2 vs. <3) and method of heliox use (studies designed to washout air in the lungs and replace it with heliox versus studies that used heliox to deliver nebulized therapy).
		At this time, heliox treatment does not have a role to play in the initial treatment of patients with acute asthma.
	www.update-software.com /abstracts/AB002884.htm (599 words)

	Neuropsychological effects of diving
		In the heliox QrouiD there was a marked increase of tremor and EEG slow-waves, and a reduction of EEG alpha band activity and hand-grip strength.
		For the heliox group there was a marked increase in tremor and EEG slow waves and reduction of hand grip strength.
		Dizziness and tremor were the main symptoms in the heliox group, whereas the trimix group reported concentration difficulties, euphoria and upset stomach during the saturation stages.
	www.fou.uib.no /drgrad/1983/300003 (1100 words)

	Heliox for Status Asthmaticus? -- Manthous 123 (3): 676 -- Chest
		Heliox is a mixture of oxygen and helium that has
		heliox was associated with a 30% reduction in pulsus
		Thus, it is premature to conclude that heliox
	www.chestjournal.org /cgi/content/full/123/3/676?etoc (973 words)

	News - Albuterol Nebulized With Heliox Better In Acute Asthma Exacerbation
		Researchers from the University of Chicago in Illinois studied the spirometric effects of albuterol nebulized with heliox during emergency room visits by 45 patients with asthma.
		Twenty-three patients were randomised to albuterol nebulized with heliox and 22 patients to albuterol nebulized with oxygen.
		After the second treatment, it was 51.5 percent in the heliox group and 22.7 percent in the controls.
	www.docguide.com /news/content.nsf/news/8525697700573E1885256BB2006F1336 (333 words)

	MedEdCenter (Site not responding. Last check: 2007-10-22)
		Heliox acts like oil and vinegar, as soon as you finish mixing it up and pour it out it starts to separate.
		Heliox provides palliative care only (relieves symptoms, doesn't fix the cause of the disease), and should be used only until definitive care corrects the underlying problem.
		For the heliox is 80%-20% the correction factor is 1.8, for the heliox is 70%-30% mixture the correction factor is 1.6 (e.g.
	www.mededcenter.com /module_viewer.asp?module=117&source=bandb (3066 words)

	[No title]
		Heliox is widely used as a breathing mixture for deep-sea diving for reasons that are well established: when the nitrogen component of air is completely replaced by helium, this overcomes the narcotic effect caused by breathing nitrogen at the pressures prevalent at 50 metres’ depth and more.
		However, it rapidly became clear that heliox had another major advantage in that it was four times less dense than air, and hence four times easier to breathe.
		One more interesting detail: heliox provided a proportionally greater improvement in performance in the most severely affected patients as much or more than is seen in those who have undergone lung volume reduction surgery.
	www.ersnet.org /ers/show/default.aspx?id_attach=7123 (799 words)

	Heliox Technologies Inc. - Advanced systems for rebreather and scuba diving (Site not responding. Last check: 2007-10-22)
		Heliox Technologies Inc. is an innovative technology company that specializes in the creation of advanced diving products.
		Heliox would like to thank everyone for the warm reception at the 2005 DEMA show.
		We would like to extend special thanks to IANTD for allowing is to exhibit in their booth and providing exceptional hospitality.
	www.heliox.com (243 words)

	CDNN :: Medical Researchers Find Heliox 28 Scuba Gas Helps Asthma Patients
		What is more, less than half as many patients in the heliox group had to stay in intensive care for more than four days.
		These were medical air with 21% oxygen, air with a slightly enriched oxygen content of 28% and two heliox mixtures, heliox 21 and heliox 28, in which the nitrogen component of the first two gases was replaced by helium.
		Heliox 21 was found to be equivalent to the 28% oxygen mixture in improving walking endurance and slightly better at reducing post-exertion dyspnoea.
	www.cdnn.info /safety/s040913b/s040913b.html (653 words)

	Heliox for asthma in the emergency department: a review of the literature -- Reuben and Harris 21 (2): 131 -- Emergency ...
		Heliox for asthma in the emergency department: a review of the literature -- Reuben and Harris 21 (2): 131 -- Emergency Medicine Journal
		Heliox for asthma in the emergency department: a review of the literature
		Heliox already has confirmed benefit as well as one or two areas
	emj.bmjjournals.com /cgi/content/abstract/21/2/131 (196 words)

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