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Topic: Hematological


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In the News (Thu 24 Dec 09)

  
  Hematological malignancy - Wikipedia, the free encyclopedia
Although hematological malignancies are a form of cancer, they are generally treated by specialists in hematology, although in many hospitals oncology specialists also manage these diseases.
Hematological malignancies are the types of cancer that affect blood, bone marrow and lymph nodes.
As the three are intimately connected through the immune system, a disease affecting one of the three will often affect the others as well: although lymphoma is technically a disease of the lymph nodes, it often spreads to the bone marrow, affecting the blood and occasionally producing a paraprotein.
en.wikipedia.org /wiki/Hematological_malignancy   (389 words)

  
 BioMed Central | Full text | Allergic conditions and risk of hematological malignancies in adults: a cohort study   (Site not responding. Last check: 2007-10-13)
Four of the studies primarily lend support to the antigenic stimulation hypothesis for hematological malignancies, as increased risks, or tendencies toward increased risks, were found for a history of allergy [6,15,18,19], whereas two of them support the immune surveillance hypothesis by showing decreased risks [16,17].
We identified 324 subjects with hematological malignancies; 10 cases of HD (ICD-7 201), 112 cases of NHL (ICD-7 200.0–200.3, 202.0–202.4), 75 cases of myeloma (ICD-7 203) and 134 cases of leukemia (ICD-8 204.0–207.9).
Therefore the exposure is not subject to differential misclassification, which is in contrast to retrospective case-control studies where recall bias may be a problem [2,3,9] and where separating the effects of prior allergic conditions from the effect of malignancy per se on the immune system may be difficult.
www.biomedcentral.com /1471-2458/4/51   (3477 words)

  
 SPLENECTOMY FOR HEMATOLOGICAL DISEASES:
For the evaluation of the hematological response to splenectomy in hypersplenism, the pretransfusion level nearest to the date of splenectomy was taken as the preoperative value, and the mean of multiple estimations performed postoperatively and during outpatient follow-ups as the postoperative value.
The indications for splenectomy in hematological disorders vary from one part of the world to the other, based on the prevalence of such diseases in that region.
Splenectomy for hematological disorders in the Eastern Province of Saudi Arabia.
www.kfshrc.edu.sa /annals/194/98-301.html   (3560 words)

  
 RedOrbit - Health - Infections of Febrile Neutropenic Patients in Malignant Hematological Diseases (Second Study Period)   (Site not responding. Last check: 2007-10-13)
Sixty-one febrile episodes among 27 neutropenic patients with malignant hematological diseases were studied during a study period between 1998 and 2001.
As mentioned in our previous article,1 the reason for the success achieved in the field of supportive therapy for patients with malignant hematological diseases is that the working groups of different institutions regularly publish the results of microbiological examinations and the effectiveness of the antimicrobial therapy used.
For the study, we selected patients with malignant hematological diseases who developed a fever (twice or more within 24 hours, with an axillary temperature of ≥38C) within 21 days after chemotherapy and who had an absolute neutrophil granulocyte count of ≤500 cells/mm^sup 3^ during the febrile period.
www.redorbit.com /news/display?id=214338&source=r_health   (1942 words)

  
 Management of the hematological manifestations of HIV infection and AIDS.   (Site not responding. Last check: 2007-10-13)
Hematological abnormalities, characterized by cytopenias, are a problem commonly encountered by persons with HIV or AIDS.
An understanding of the various causes of these cytopenias and the appropriate nursing care are tantamount to nursing practice and to ensure quality of life.
Goals of medical and nursing care are directed at assessment, interventions, and patient education to prevent or minimize the complications of hematological abnormalities.
www.aegis.com /aidsline/1996/mar/M9630472.html   (335 words)

  
 VCU Services & Programs: Hematological Malignancy Clinic   (Site not responding. Last check: 2007-10-13)
By working together and pooling their expertise, Hematological Malignancy Clinic doctors are able to make the best decisions and give you the most comprehensive advice and information.
A: The Hematological Malignancy Clinic is the only clinic of its kind in the Richmond area.
A: Patients with a suspected or diagnosed hematologic or lymphoproliferative disorder including leukemia, lymphoma, and multiple myeloma.
www.vcuhealth.org /program-details.asp?programID=46   (655 words)

  
 Hematological Complications in Obstetrics, Pregnancy, and Gynecology - Cambridge University Press   (Site not responding. Last check: 2007-10-13)
$160.00 (M) There are many hematological complications associated with obstetrics, pregnancy and gynecology, and unfortunately, they often lead to significant morbidity or mortality for both mother and child.
As the first comprehensive reference on all aspects of hematological complications of obstetrics, pregnancy and gynecology this book will be a valuable resource to hematologists, obstetricians, gynecologists, reproductive medicine specialists, internists, anesthesiologists and others.
The chapters are written by acknowledged experts in the field, and for each condition covered the etiology, pathophysiology, clinical and laboratory diagnosis and management are discussed where appropriate.
www.cambridge.org /us/catalogue/catalogue.asp?isbn=052183953X   (460 words)

  
 Hematological Disorders — Emergency Medical Services (EMSResponder.com)
Hematologic crises are caused by a sudden exacerbation of anemia and a corresponding decrease in hemoglobin.
Patients with a hematological disorder may have a complicated medical history, which requires EMS providers to perform a thorough assessment and physical exam.
Hematological disorders are rare in the prehospital arena; however, it is important to understand the physiology behind these disease states.
www.emsmagazine.com /features/article.jsp?id=1741&siteSection=16   (4253 words)

  
 Patients With Hematological Disorders Requiring Admission To Medical Intensive Care Unit In A Developing Country
Hematological disorders are increasingly being treated over the past two decades in developing countries.
This study was conduced with a view to assess the utility and outcome of patients with hematological disorders requiring ICU in a tertiary care center.
The various hematological diagnosis of the study subjects are given in Table 1.
www.ispub.com /ostia/index.php?xmlFilePath=journals/ijeicm/vol7n2/micu.xml   (3007 words)

  
 Hematological indices in an older population sample: derivation of healthy reference values -- Tsang et al. 44 (1): 96 ...
Hematological indices in an older population sample: derivation of healthy reference values -- Tsang et al.
Hematological indices in an older population sample: derivation of healthy reference values
Factors having a significant effect on hematological indices, by sex.
www.clinchem.org /cgi/content/full/44/1/96   (2205 words)

  
 Invasive Infections Caused by Trichosporon Species and Geotrichum capitatum in Patients with Hematological ...
Fusarium, a significant emerging pathogen in patients with hematologic malignancy: ten years' experience at a cancer center and implications for management.
Genotyping and antifungal susceptibility profile of Dipodascus capitatus isolates causing disseminated infection in seven hematological patients of a tertiary hospital.
Trichosporon beigelii pneumonia in patients with hematologic malignancies.
jcm.asm.org /cgi/content/full/43/4/1818   (6784 words)

  
 Pharmacokinetics and Hematological Effects of the PEGylated Thrombopoietin Peptide Mimetic GW395058 in Rats and Monkeys ...
Changes in average hematological and coagulation parameters at the end-of-dose and postdose at two and four weeks are shown for rats receiving repeated i.v.
Hematological effects of GW395058 in cynomolgus monkeys after one-month repeat-dose studies.
Changes in average hematological and coagulation parameters at the end-of-dose and postdose at two and four weeks are shown for monkeys receiving repeated i.v.
stemcells.alphamedpress.org /cgi/content/full/17/6/316   (4152 words)

  
 UVa Cancer Center Hematological Malignancies Team
The Hematologic Malignancy Team specializes in cancers of the blood and lymphatic systems, including acute and chronic leukemias, Hodgkin's lymphoma, non-Hodgkin's lymphoma, mycosis fungoides, multiple myeloma, Sezary syndrome, cutaneous cancer, and Waldenström's Macroglobulinemia.
Clinical trials are offered for many disorders, with a special focus on monoclonal antibody, vaccine and novel targeted therapy approaches.
The Hematologic Malignancy Team is part of the University of Virginia Cancer Center, which is a highly-ranked National Cancer Institute designated Cancer Center
www.healthsystem.virginia.edu /internet/cancer-patients/teams/doctors-hem-onc.cfm?C=M;O=A   (229 words)

  
 Phase II Trials Of Aplidin Begin In Hematological Cancers
Aplidin is already in phase II trials in a number of solid tumour indications, the results of which are expected in 2005.
The commencement of the phase II hematology trials follows a number of preclinical studies and phase I trials in which Aplidin demonstrated activity in hematological malignancies as well as a favorable safety profile.
Indeed, the combination of Aplidin with the standard agents used to treat malignant hematological diseases increases their cytotoxic effect against these cell lines in vitro and in vivo.
www.cancercompass.com /cancer-news/1,8365,00.htm   (445 words)

  
 BM Transplantation In Hematological Disorders - An Iranian Experience   (Site not responding. Last check: 2007-10-13)
This study describes an eight-year experience at the Shiraz University of Medical Sciences, Iran, for treatment of hematological disorders with bone marrow (BM) transplantation.
A total of 120 cases underwent bone marrow transplantation of which 80 cases were of thalasssemia major, 35 cases suffered from leukemia and five patients had aplastic anemia.
Thus bone marrow transplantation is an effective curative therapy for several life threatening hematological disorders.
www.indegene.com /Ped/Jour/indJour_IJP_Sum_01-01-2002_4.asp   (183 words)

  
 Dietary, anthropometric, hematological and biochemical assessment of the nutritional status of centenarians and elderly ...
Dietary, anthropometric, hematological and biochemical assessment of the nutritional status of centenarians and elderly people in Okinawa, Japan -- Chan et al.
Dietary, anthropometric, hematological and biochemical assessment of the nutritional status of centenarians and elderly people in Okinawa, Japan
hematological and biochemical parameters was poor in the centenarian
www.jacn.org /cgi/content/abstract/16/3/229   (511 words)

  
 Hematological Cancer Therapeutics   (Site not responding. Last check: 2007-10-13)
Hematological Cancer Therapeutics: Pipelines and Competition provides a realistic assessment of how newly-approved drugs and candidates in development will impact this sector of the cancer treatment field within the next decade.
Characterizes hematological cancers and the use of various diagnostic technologies in conjunction with therapy selection and disease monitoring.
Reviews newly licensed or advanced clinical-stage compounds—antimetabolites, inhibitors of DNA unwinding or transcription, or inhibitors of kinase-modulated intracellular pathways—under development at a multitude of small oncology companies for leukemias and myelodysplastic syndromes, lymphomas (Hodgkin’s disease, non–Hodgkin’s lymphoma, mantle cell lymphoma), and multiple myeloma.
www.advancesreports.com /all_reports/2005_53_BloodCancer/overview.html   (554 words)

  
 [Splenectomy in immune thrombocytopenia and other hematological diseases]
The Authors report a retrospective study of 74 splenectomies performed for hematologic diseases.
In selected patients the splenectomy has the potential to relieve symptoms due to splenomegaly, correct cytopenias, specify hystological diagnosis and modify the disease course of malignant lymphomas.
In fact splenomegaly sometimes complicated the course of malignant lymphomas because of hematologic abnormalities that are inconsistent with active chemotherapy.
www.aegis.com /aidsline/2000/apr/A0040662.html   (425 words)

  
 Aranesp®-ONS Hematological Toxicity Center   (Site not responding. Last check: 2007-10-13)
The ONS clinical practice resource area dedicated exclusively to the hematologic side effects of cancer treatment.
Therapies to manage the hematologic side effects of cancer treatment are advancing rapidly.
ONS, with sponsorship from Amgen, is providing this resource area to keep our members up to speed on the latest news and developments in the field.
www.aranesp.com /professional/cia/for_nurses/educational_tools/ons_toxicity_center.jsp   (302 words)

  
 BioSeeker Group AB - Hematological Cancers - A Therapeutic & Competitive Insi
Consequently, the historical general conception that relatively low prevalence diseases, has been insufficient in size to allow companies to quickly regain their investment is clearly out of date.
BioSeeker Group has studied the progress of 125 of the most prominent drugs in development for the treatment of hematological cancers.
Gain insight into the current challenges and commercial opportunities associated with therapy for the hematological cancers.
www.bioseeker.com /component/page,shop.product_details/flypage,shop.flypage/product_id,3443/option,com_virtuemart/Itemid,1   (712 words)

  
 Midwestern Regional Medical Center: Hematological Center
Hematological Oncology at Midwestern Regional Medical Center utilizes high-powered chemotherapies and radiotherapies, alone, or in concert with pioneering immunotherapies, to deliver advanced cancer care to patients fighting hematologic malignancies.
Spearheading the expansion into immunotherapy is CTCA partner and world-renowned Hematologic Oncologist, Dr. Shimon Slavin.
Together, Dr. Slavin and Midwestern’s Hematologic Oncology Department are working to share common protocols that are changing the face of cancer treatment.
www.cancercenter.com /midwestern-hospital/departments/hematological-bmt-center.cfm   (158 words)

  
 Discussions on Rare Hematological Disorder to be Held at University of Washington, Seattle   (Site not responding. Last check: 2007-10-13)
Discussions on Rare Hematological Disorder to be Held at University of Washington, Seattle
Neutropenia encompasses a group of rare hematologic disorders in which the patient's absolute neutrophil count (ANC) falls below 500 cells per cubic millimeter.
In most cases, SCN is due to underproduction of neutrophils in the bone marrow.
www.prweb.com /releases/2006/7/prweb413940.htm   (686 words)

  
 Expression in Hematological Malignancies of a Glucocorticoid Receptor Splice Variant That Augments Glucocorticoid ...
Expression in Hematological Malignancies of a Glucocorticoid Receptor Splice Variant That Augments Glucocorticoid Receptor-mediated Effects in Transfected Cells -- de Lange et al.
Genetic abnormalities of the GR are not a common cause of GC resistance in hematological malignancies.
The cause of GC resistance in hematological malignancies is
cancerres.aacrjournals.org /cgi/content/full/61/10/3937   (4301 words)

  
 107.00-Hematological-Childhood
Refers to a chronic hemolytic anemia associated with sickle cell hemoglobin, either homozygous or in combination with thalassemia or with another abnormal hemoglobin (such as C or F).
Appropriate hematologic evidence for sickle cell disease, such as hemoglobin electrophoresis must be included.
Vaso-occlusive, hemolytic, or aplastic episodes should be documented by description of severity, frequency, and duration.
www.ssa.gov /disability/professionals/bluebook/107.00-HemicandLymphatic-Childhood.htm   (239 words)

  
 UPCI | clinical research | hematological malignancies program | overview
The Hematological Malignancies Program of the University of Pittsburgh Cancer Institute researches the mechanisms involved with the onset and progress of blood disorders, and also studies novel methods by which these processes can be altered.
Accordingly, much of the Program's research is focused on the genetic and cellular origins of leukemia, lymphoma and myeloproliferative disorders, as well as the development of agents used in treating hematologic malignancies.
The Multiple Myeloma group was created in 2001 as part of the Hematological Malignancies Program to focus on the causes of, and novel treatments for, multiple myeloma.
www.upci.upmc.edu /research/clinical/hemmalig   (183 words)

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