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	Hemophilia: Encyclopedia of Nursing & Allied Health
		Hemophilia is a genetic disorder of the mechanism of blood clotting that is usually inherited.
		Hemophilia C involves factor XI, is very rare, and much more mild than hemophilia A or B. Hemophilia A and B are both caused by a genetic defect present on the X chromosome.
		About 30% of all people with hemophilia A or B are the first member of their family to ever have the disease.
	health.enotes.com /nursing-encyclopedia/hemophilia (1927 words)

	Hemophilia - Definition, Description, Causes, Symptoms, Diagnosis, Treatment, Prognosis, Prevention (Site not responding. Last check: 2007-10-05)
		Hemophilia B is caused by a defective clotting factor known as factor IX.
		The range of symptoms of hemophilia B is similar to that of hemophilia A. Hemophilia C is very rare and is much more mild that hemophilia A or B. It is caused by a defective clotting factor known as factor XI.
		Hemophilia A and B are both caused by a genetic defect present on the X chromosome.
	www.faqs.org /health/Sick-V2/Hemophilia.html (2104 words)

	HerbChina2000.com - Herbal Remedies - Hemophilia
		Hemophilia A, also known as classic hemophilia, is the most common type of hemophilia, occurring in about 80 percent of people with the disorder.
		Hemophilia B, also known as Christmas disease (named after the family in whom it was first diagnosed), accounts for 12 percent to 15 percent of hemophilia cases.
		Hemophilia A, B and C are inherited diseases.
	www.herbchina2000.com /therapies/HPL.shtml (997 words)

	Healthy Living - What is Hemophilia? (Site not responding. Last check: 2007-10-05)
		Hemophilia occurs in three types — hemophilia A, hemophilia B and hemophilia C — depending on which clotting factor is deficient.
		Hemophilia A, B and C are inherited diseases.
		The cause of hemophilia is a deficiency of one of several of your blood's clotting factors.
	www.healthierliving.org /newsletter/200203/hemophilia.html (743 words)

	Hemophilia Symptoms - Medical Symptoms Pages
		Hemophilia is the name of any of several hereditary genetic illnesses that impair the body's ability to control bleeding and blood loss.
		With Hemophilia, when a blood vessel is injured, a scab will not form and the vessel can continue to bleed excessively for a very long period of time, often until all blood is lost.
		Hemophilia C: is a mild form of hemophilia that mainly occurs in Jews of Ashkenazi descent.
	www.symptoms101.com /med/archives/2005/07/hemophilia.php (296 words)

	The Hemophilias: Genetic Disorders Passed from Mother to Son
		Hemophilia is a blood disorder that prevents blood from clotting properly, leading to uncontrolled bleeding.
		Hemophilia A is responsible for eighty percent of all cases.
		Hemophilia C affects factor XI proteins, and is unusual in that it affects both males and females.
	www.causes-of-hemophilia.com (420 words)

	Adult Health Advisor 2005.4: Hemophilia
		Hemophilia C, a much rarer form, occurs when factor 11 is low or missing.
		Most cases of hemophilia are diagnosed in the first 2 years of a child's life based on family history, unusual bleeding, and blood tests.
		If the symptoms are mild and hemophilia is not suspected because the family history is not available or does not suggest bleeding problems, the diagnosis may not be made until a child is several years old.
	www.med.umich.edu /1libr/aha/aha_hemophil_crs.htm (718 words)

	Home \| aHealthyme.com
		Hemophilia A and B are both caused by a genetic defect present on the X chromosome.
		Hemophilia is a genetic disorder-usually inherited-of the mechanism of blood clotting.
		Hemophilia C is very rare, and much more mild than hemophilia A or B; it involves factor XI.
	www.ahealthyme.com /article/gale/100084679 (2119 words)

	Hemophilia (Site not responding. Last check: 2007-10-05)
		Hemophilia is the oldest known hereditary bleeding disorder.
		Approximately 85% have hemophilia A and the remainder has hemophilia B. The severity of hemophilia is related to the amount of the clotting factor in the blood.
		Hemophilia is known to be caused by defects in the genes for factor VIII and factor IX.
	www.medceu.com /tests/hemophilia.htm (1342 words)

	Coagulation disorders
		Hemophilia C afflicts one in 100,000 people and is the second most common bleeding disorder among women.
		Hemophilia B symptoms are similar to those of hemophilia A, including numerous, large and deep bruises and prolonged bleeding.
		Hemophilia most often occurs in families with a known history of the disease, but occasionally, new cases will occur in families with no apparent history.
	www.lifesteps.com /gm/Atoz/ency/coagulation_disorders.jsp (2761 words)

	Hemophilia - Definition, Description, Demographics, Causes and symptoms, Diagnosis, Treatment, Prognosis, Prevention, ...
		In hemophilia B, or Christmas disease, the deficient clotting factor is factor IX, but the symptoms are very similar to those of hemophilia A. Factor IX is produced in the liver and is dependent on interaction with vitamin K in order to function properly.
		Hemophilia C is rare and much milder than hemophilia A or B. It involves reduced activity of factor XI and is characterized by mild bleeding such as nosebleeds (epistaxis) or prolonged menstrual bleeding, or mild bleeding after tonsillectomies or dental extractions.
		Hemophilia B occurs in one in 40,000 to 50,000.
	www.healthofchildren.com /G-H/Hemophilia.html (2617 words)

	Hemophilia Pediatric Oncall (Site not responding. Last check: 2007-10-05)
		A: Hemophilia is an inherited disorder in which there is inability to form an effective clot and hence causes prolonged bleeding in a patient.
		Female carriers of hemophilia may be symptomatic due to lower than normal clotting factor levels.
		It is the deficiency of factor VIII or IX in the intrinsic pathway that causes hemophilia.
	www.pediatriconcall.com /fordoctor/diseasesandcondition/hemophilia.asp (2274 words)

	Dorlands Medical Dictionary (Site not responding. Last check: 2007-10-05)
		C a common abnormal hemoglobin in which lysine replaces glutamic acid at position six of the β chains; it was one of the earliest hemoglobins to have its molecular abnormality defined.
		C an autosomal disorder due to lack of coagulation factor XI; seen predominantly in persons of Ashkenazi Jewish ancestry and characterized by recurring episodes of minor bleeding and mild bruising, menorrhagia, severe prolonged postsurgical bleeding, and prolonged recalcification and partial thromboplastin times.
		American physician; co-winner, with Edward C. Kendall and Tadeus Reichstein, of the Nobel prize for medicine or physiology in 1950 for his treatment of rheumatoid arthritis with ACTH and cortisone.
	www.mercksource.com /pp/us/cns/cns_hl_dorlands.jspzQzpgzEzzSzppdocszSzuszSzcommonzSzdorlandszSzdorlandzSzdmd_h_07zPzhtm (3936 words)

	Hemophilia
		Hemophilia is caused by deficiency in one of clotting factors.
		Hemophilia A. This is the most common type of hemophilia, resulting from deficiency in clotting factor VIII.
		Hemophilia B. This type is caused by deficiency in clotting factor IX.
	www.web-books.com /eLibrary/Medicine/Blood/Hemophilia.htm (350 words)

	[No title]
		Hemophilia is a perfect candidate for gene therapy research: the disease is caused by mutations to a single gene.
		Hemophilia could be cured if clinical trials discover a way to replace or "repair" the defective gene.
		If the mother carries the gene for hemophilia on one of her X chromosomes (girls have two X chromosomes), each of her sons will have a50% chance of having hemophilia.
	www.lycos.com /info/hemophilia--diseases.html (390 words)

	eMedicine - Hemophilia C : Article Excerpt by: Prasad Mathew, MBBS, DCH
		Hemophilia C can be distinguished from hemophilia A (deficiency of factor VIII) and hemophilia B (deficiency of factor IX) by the absence of bleeding into joints and muscles and by its occurrence in individuals of either sex.
		Unlike the bleeding tendency in hemophilia A or B, which is clearly related to the factor level, the bleeding risk in hemophilia C is not always influenced by the severity of the deficiency, especially in individuals with partial deficiency.
		In the United Kingdom, 383 patients with hemophilia C were registered in a population of 58 million; therefore, hemophilia C represents 3% of inherited coagulation disorders.
	www.emedicine.com /ped/byname/hemophilia-c.htm (519 words)

	Hemophilia - New Treatments, May 2, 2007
		Hemophilia C, or more properly factor XI deficiency, will be considered separately, since the clinical syndromes are quite different and vary considerably.
		While the clinical conditions of hemophilia A and B remain indistinguishable, the proteins in which defects produce the disorders of Classic hemophilia A and hemophilia B or Christmas disease (Factor VIII and Factor IX, respectively) were separated from each other.
		Patients with severe hemophilia bleed spontaneously, most often into joint cavities (hemarthroses); those with moderate hemophilia bleed less often on a spontaneous basis and more commonly associated with minor trauma; those with mild hemophilia often are asymptomatic until provoked with surgical stress or severe trauma.
	www.ccspublishing.com /journals5a/hemophilias.htm (644 words)

	Hemophilia (Site not responding. Last check: 2007-10-05)
		Data were collected in the homes and schools of 40 boys with hemophilia and 40 comparison boys of the same...
		Depending on the critical clotting factor missing, the disorder is identified as Hemophilia A, Hemophilia B, Von Willebrand Disease, or another rarer...
		Le hemophilia es un morbo hereditari characterisate per le inadequate coagulation del sanguine e le consequente tendentia abnormal pro haber hemorrhagias.
	interlingua.encyclopedia.st /Hemophilia (423 words)

	Personalized Medication Management for Bleeding Disorders (Hemophilia)
		Hemophilia occurs in three types -- A, B and C -- depending on which clotting factor is deficient.
		Hemophilia C is rare, occurring in approximately one in 100,000 Americans.
		Generally, hemophilia A and B pass from mother to son through one of the mother's genes.
	www.mayoclinic.org /specialty-pharmacy/hemophilia.html (1138 words)

	Corporate Support (Site not responding. Last check: 2007-10-05)
		Hemophilia is a rare sex-linked, hereditary coagulation disorder that causes excessive bleeding to occur spontaneously and/or after injury.
		Hemophilia is caused by a defect in the gene located on the X chromosome that contains the genetic code for one of the clotting factor proteins necessary for normal clotting.
		The defective gene is carried by the mother and passed on to her sons with a 50% chance of inheritance and her daughters have a 50% chance of inheriting carrier status.
	www.hemophiliafed.org /faq.html (1801 words)

	Hemophilia, HIV, Hepatitis C HCV Lawsuit: 2006 Update
		The plaintiffs allegedly became infected with the HIV and/or Hepatitis C ("HCV") viruses from exposure to virus-contaminated Factor VIII and IX.
		Tens of thousands of people with hemophilia worldwide were infected with HIV and/or HCV from the late-1970s through the 1980s after receiving Factor VIII and IX infusions from blood plasma that was originally gathered, processed and manufactured in the United States by Armour, Cutter, Baxter and Alpha or their subsidiaries.
		People with hemophilia from outside the U.S. who were infected with HIV and/or HCV and from the U.S. with HCV but not also HIV, or the families of loved ones who have passed away, should click here to contact a Lieff Cabraser attorney.
	www.hemophilia-litigation.com (844 words)

	Welcome to BiotechWatch.com (Site not responding. Last check: 2007-10-05)
		People with hemophilia are more likely to receive blood transfusions and are at greater risk of receiving contaminated blood products.
		Some people with hemophilia develop proteins in their blood that inactivate clotting factors used to treat bleeding.
		If you have hemophilia, wear a medical alert bracelet to let medical personnel know of your condition and the type of clotting factor that's best for you in case of an emergency.
	www.biotechwatch.com /knowledge_base/MayoClinic/hemophilia.html (1271 words)

	InteliHealth:
		Hemophilia is an inherited (genetic) disorder that prevents blood from clotting properly.
		In most cases, the defective gene that leads to hemophilia is passed down through several generations, but in about 20% of cases, the defect arises as a spontaneous mutation (a new DNA defect) in the parent or affected child.
		Hemophilia B, also known as Christmas disease (named after the family in whom it was first diagnosed), accounts for 12% to 15% of hemophilia cases.
	www.intelihealth.com /IH/ihtIH/WSIHW000/9339/10115.html (1598 words)

	UC News: Hemophiliacs with Hepatitis C and AIDS Studied (Site not responding. Last check: 2007-10-05)
		Hemophilia is a bleeding disorder in which certain factors in the blood needed to form a clot are missing or reduced, resulting in difficulty controlling hemorrhage.
		Beginning in 1987, the heat treatments that were used to pull factor concentrates from the blood killed hepatitis C. Screening donated blood for HIV began in 1985.
		Universal screening of blood donations for hepatitis C was implemented in 1992.
	medcenter.uc.edu /news/bhemophiliac.ucm (599 words)

	From the Grand Rounds Archive at Baylor
		Factor IX is often commonly measured since Hemophilia C is the third most common inherited bleeding disorder.
		Hemophilia A and von Willebrand's Disease are the most common congenital coagulation disorders and both involve different components of factor VIII macromolecule.
		Hemophilia A or classic hemophilia is inherited as a sex-linked recessive and is a deficiency or defect in factor VIII:C. Disease severity is determined by the circulating levels of Factor VIII:C. Treatment consists of Factor VIII:C replacement.
	www.bcm.edu /oto/grand/11394.html (2025 words)

	Disorders IHTC
		Hemophilia is classified by the functional level of the clotting factor present in the blood.
		Mild and moderate deficient hemophilia and von Willebrand disease are under-recognized disorders.
		Those with mild hemophilia tend to have infrequent bleeding events; such events are usually associated with injury, trauma or surgery.
	www.ihtc.org /Disorders/hemophilia.html (1578 words)

	dreddyclinic.com - Hemophilia
		The cause of hemophilia is a deficiency of one of several of your blood's clotting factors.
		Hemophilia A. The most common type, hemophilia A is caused by lack of enough clotting factor VIII.
		For people with a family history of hemophilia, it's possible to test the fetus during pregnancy to determine if the child is affected by the disease.
	www.dreddyclinic.com /findinformation/hh/hemophilia.htm (978 words)

	NORD - National Organization for Rare Disorders, Inc.
		Hemophilia is a rare inherited blood clotting (coagulation) disorder caused by inactive or deficient blood proteins (usually factor VIII).
		There are three major types of hemophilia: hemophilia A (also known as classical hemophilia, factor VIII deficiency or antihemophilic globulin [AHG] deficiency); hemophilia B (Christmas disease or factor IX deficiency); and hemophilia C (factor XI deficiency).
		Hemophilia A and B are inherited as X-linked recessive genetic traits, while Hemophilia C is inherited as an autosomal recessive genetic trait.
	www.rarediseases.org /search/rdbdetail_abstract.html?disname=Hemophilia (431 words)

	Law Office of Peter D. Hoffman, P.C., lawyers in Katonah, NY, New York (Site not responding. Last check: 2007-10-05)
		I am personally and professionally committed to seeking justice for persons with hemophilia and their families who have been impacted by this epidemic of viral contamination and infection.
		This litigation concerns American persons with hemophilia, or their survivors and estates, who from 1978 to 1992, were infected with HCV, but not American persons with hemophilia also co-infected with HIV.
		Through the lawsuit, persons with hemophilia and HCV seek to require that the American companies that made these contaminated products acknowledge their responsibility, and provide compensation.
	www.peterhoffmanlaw.com /HemophiliaandHCVLitigationNewsletter.jsp (658 words)

	End-stage liver disease in persons with hemophilia and transfusion-associated infections -- Goedert et al. 100 (5): ...
		Other collaborators and institutions of the Multicenter Hemophilia Cohort Study are listed in the Appendix at the end of this article.
		Hepatitis C antibody and chronic liver disease in haemophilia.
		Prevalence of hepatitis C virus antibody in a cohort of hemophilia patients.
	www.bloodjournal.org /cgi/content/full/100/5/1584 (3709 words)

	Blood coagulation in hemophilia A and hemophilia C. (Site not responding. Last check: 2007-10-05)
		Blood coagulation in hemophilia A and hemophilia C. Blood coagulation in hemophilia A and hemophilia C.Replacement with recombinant factor VIII normalized the rate of TAT generation.
		In hemophilia A blood (factor VIII:C <1%) treated with 25 pmol/L TF, clotting was significantly delayed versus normal, whereas replacement with recombinant factor VIII (1 U/mL) restored the clot time near normal values.
		Thus, coagulation in hemophilia A blood at 25 pmol/L TF is impaired, with significantly slower thrombin generation than normal during the propagation phase; this reduced thrombin appears to affect FPA production and factor V activation more profoundly than platelet activation.
	www.pdg.cnb.uam.es /UniPub/iHOP/gp/1458480.html (415 words)

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