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Topic: Henri Laborit

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	INFOAMÉRICA - Henri Laborit
		Laborit describe una realidad compleja, dinámica e interrelacionada, como escenario sistémico de la vida del ser social.
		La vida del individuo, viene a señalar Laborit, transcurre generalmente en un espacio físico limitado, pero los medios de comunicación crean la sensación de pertenencia a un espacio planetario.
		Henri Laborit, l'éloge de l'homme imaginant por Bernard Andrieu (en francés).
	www.infoamerica.org /teoria/laborit1.htm (766 words)

	Body
		Laborit's early theory, validated twenty years after he came up with it [sound like Gabor?], was that most pathologies arise from situations where our third system, the 'action inhibiting system', is activated for extended periods.
		Laborit was induced by his own understanding of the human nervous system, to eschew the hierarchy represented by his own discipline and to pursue his research independently (see appended biography).
		Laborit's message is, instead, that if we respond to our feelings (emotions) alone, without the use of our imagination, we can get stuck in the gap between 'fight or flight' and if we can't flee, then we're in for anguish and open to pathology.
	www.goodshare.org /laborit.htm (3961 words)

	Henri Laborit - Wikipedia, the free encyclopedia
		Henri Laborit (November 21, 1914 - May 18, 1995) was a French physician, writer and philosopher.
		He was born in Hanoi, Vietnam and started his career as a surgeon in the Marine and then moved on to fundamental research.
		The drug GHB was first synthesized in the early 1960s by Laborit to use in studying the neurotransmitter GABA.
	en.wikipedia.org /wiki/Henri_Laborit (216 words)

	Henri Laborit - Wikipedia, la enciclopedia libre
		Henri Laborit (Hanoi 21 de noviembre de 1914 - París 18 de mayo de 1995).
		Henri Laborit dejó escritos más de 30 libros, que fueron traducidos a varios idiomas.
		Henri Laborit en Infoamérica (Biografía, pensamiento y resursos).
	es.wikipedia.org /wiki/Henri_Laborit (1354 words)

	Des hommes-
		Par ailleurs, il est temps pour Laborit de passer au grade de médecin-colonel, ce qui suppose un embarquement de plusieurs mois.
		On demande à Laborit de comprendre pourquoi s'opère cette transformation et de découvrir une drogue protectrice de l'organisme.
		En effet, lorsque Laborit et son équipe écrivent la formule du gamma OH, rien ne leur permet de supposer que la nature en a fabriqué avant eux.
	www.geocities.com /Athens/Crete/9445/gamma.html (4919 words)

	Henri Laborit (Site not responding. Last check: 2007-10-09)
		Des périodes difficiles, Henri Laborit en aura eu beaucoup, n'obtenant jamais la reconnaissance qu'il méritait.
		Même si la découverte des neuroleptiques constitue le plus grand bouleversement de la psychiatrie, on crédite en général Henri Laborit plutôt de son apport à la théorie de l'inhibition et du stress, ce qu'il appelait l'Agressologie.
		Henri Laborit ne se privait pas de critiquer les hiérarchies au nom du stress qu'elles faisaient subir aux dominés, n'hésitant pas à tirer les conséquences politiques de la découverte de l'origine sociale des perturbations biochimiques, ce qui n'était pas du goût de l'époque.
	www.globenet.org /transversales/grit/laborit.htm (1177 words)

	Joël de Rosnay - Articles - Hommage à Henri Laborit (via CobWeb/3.1 planetlab2.isi.jhu.edu) (Site not responding. Last check: 2007-10-09)
		La méthode Laborit lui permet de produire des molécules d'intérêt thérapeutique en évitant le screening massif caractéristique de la recherche pharmaceutique moderne.
		Henri Laborit nous propose aussi de nouveaux modes de vie en relation avec notre environnement.
		Henri Laborit, homme total et libre dans l'univers fragmenté des disciplines, restera en cette fin du 20 siècle comme un pionnier de la pensée complexe et l'inspirateur d'un nouveau sens de la vie.
	csiweb2.cite-sciences.fr.cob-web.org:8888 /derosnay/articles/labo.htm (1065 words)

	Rp./internet - Henri Laborit
		Ese mismo año el gran público conocería la figura de Henri Laborit, inspirador y partícipe del film a través de quien se interpretan las particulares circunstancias de los personajes.
		Laborit nació en Hanoi en 1914, este médico militar francés salto a la fama cuando en 1952 utilizó por primera vez en la historia la Clorpromazina como medicación preanestésica, disminuyendo así la mortalidad postoperatoria de los heridos en batalla.
		Henri Laborit fue definido también como un filósofo del comportamiento, su visión de la célula como la fábrica donde se gesta el comportamiento y de las conductas como resultado de procesos bioquímicos y enzimáticos, generó un intenso debate del que no hubo rama del conocimiento que estuviera ajena.
	www.rpinternet.com.ar /2000/03/nota01.htm (323 words)

	GHB Meta-FAQ
		He synthesized this compound in 1960 as a possible precursor to the neurotransmitter GABA, and was taken by surprise by its effects.
		Laborit continued to work, publish, and use GHB thrice a week until his death in 1995 at the age of 81.
		It is telling that Laborit considered GHB one of his two greatest accomplishments, considering that the other was the therapeutic use of chlorpromazine (Thorazine).
	users.lycaeum.org /~ghbfaq/metafaq.html (792 words)

	GHB: The First Authentic Antidepressant
		Laborit was interested in studying the action of GABA in the nervous system, but GABA was known to be unable to cross the blood-brain barrier.
		Laborit hoped that by adding a hydroxyl (OH) group to butyric acid, the resulting molecule-GHB-would be protected from being destroyed by beta-oxidation (the process by which cells ‘burn’ fat), would cross the blood-brain barrier, and then serve as a precursor to GABA once in the brain.
		Laborit discovered that in effect, GHB serves as a switching agent to cycle brain/muscle activity from its high-energy output, "yang", daytime activities to a "yin," restorative/recuperative repair and rebuilding (anabolic) phase during night-time sleep.
	www.drugwatch.info /ap_ClaudRifat.htm (14496 words)

	TIME.com: A Killer for All Pains -- Nov. 12, 1965 -- Page 1
		His brand new painkiller, says France's Dr. Henri Laborit, dampens the aches and pains of arthritis, burns, cancer, childbirth, neuralgia, rheumatism—just about all the ills the flesh is heir to.
		It was Laborit who ferreted out the unsuspected nerve-center-depressant properties of chlorpromazine, the wonder drug of 1954, which opened up the new field of psychopharmacology (the use of drugs to influence the emotions).
		After 21 years of cautious testing Laborit reports that the intravenously administered drug enhances the effect of anesthetics, thus lowering the amount necessary for a patient, and thereby lowering the danger.
	www.time.com /time/magazine/article/0,9171,834574,00.html (714 words)

	Brain Mechanisms
		I believe that the work of Adams is very interesting; I agree with the majority of the facts he joins together and, broadly speaking, with his general model for the neural circuitry that triggers offense, defense.
		We have shown experimentally that the AIS is triggered by the memory of the inescapability of punishment, or, in others words, by the memory of the impossibility of coping with a previously experienced situation.
		It is possible to differentiate the systemic response to electrical stimulation of dorsomedial and basolateral amygdala, as well as that of dorsal and basal hippocampus (Laborit and Baron 1977; and Laborit, Baron, and Laurent 1977).
	www.culture-of-peace.info /bbs/comment11-40.html (432 words)

	General Information
		The French anesthesiologist Henri Laborit was working with the French pharmaceutical firm Rhone Polenc in attempting to discover an intraoperative anesthetic agent that would protect neurosurgical patients from the very severe and occasionally lethal postoperative edema (brain swelling) that hampered brain surgery at that time.
		When he gave these neurosurgical patients the antihistaminic compound promethazine, he noticed that while it did nothing to limit the target symptom of edema, it did induce a state of calmness in his patients that persisted for a day or so after surgery.
		Psychotic patients also demonstrated the mild sedation observed by Laborit, but an I almost miraculous antipsychotic effect clearly separate from the sedation occurred one to two weeks after beginning therapy.
	www.contac.org /contaclibrary/general11.htm (2498 words)

	A Science Odyssey: People and Discoveries: Drug for treating schizophrenia identified
		In 1952, Henri Laborit, a surgeon in Paris, was looking for a way to reduce surgical shock in his patients.
		Laborit was able to operate using much less anaesthetic.
		He was so struck by the effect on his patients, especially with a drug called chlorpromazine (trade name Thorazine) he thought the drug must have some use in psychiatry.
	www.pbs.org /wgbh/aso/databank/entries/dh52dr.html (614 words)

	Amazon.com: Biologie et structure: Books: Henri Laborit (Site not responding. Last check: 2007-10-09)
		A study of the current biological bases of the human behavior shows why and how this one is entirely dominated by the value judgments and an unsuited semantics.
		Henri Laborit tries, starting from contemporary biological knowledge, to release a methodology being able to be used as framework with a science of action.
		Molecular physics to sociology and the political economy are all dependent to each other and the role of the Modern Man is to search for these structures.
	www.amazon.com /Biologie-structure-Henri-Laborit/dp/2070324346 (661 words)

	Chemical & Engineering News: Top Pharmaceuticals: Thorazine
		It was the barbiturate-enhancing effect of chlorpromazine that led French naval surgeon Henri Laborit to it in 1951.
		Laborit was in search of a surgical anesthetic but discovered that chlorpromazine put his patients in a detached vegetative state.
		By 1952, Smith-Kline and French had purchased the rights to the drug from Rhône-Poulenc, and French psychiatrists Jean Delay and Pierre Deniker were touting the therapeutic effects that chlorpromazine had on schizophrenic patients.
	pubs.acs.org /cen/coverstory/83/8325/8325thorazine.html (664 words)

	A Science Odyssey: On The Edge: Miracle Pill: Text Version (Site not responding. Last check: 2007-10-09)
		Narrative: Ace reporter Flois Flame has just arrived at the City of Lights, Paris, France, where she has arranged an interview with Dr. Henri Laborit, the surgeon who, with his discovery of a radical new treatment, will revolutionize the way pyschiatry looks at mental illness.
		Dr Laborit: I believed that one antihistamine in particular would prove useful to psychiatry -- the name of this drug is chlorpromazine.
		Many advances have been made in the forty-six years since Dr. Laborit's discovery, which was later marketed in the U.S. as Thorazine.
	www.pbs.org /wgbh/aso/ontheedge/pill/indext.html (623 words)

	Henri Laborit - Wikipédia
		Henri Laborit (Hanoï, 21 novembre 1914 - 18 mai 1995) était un biologiste,un philosophe du comportement animal et surtout du comportement humain.
		Henri Laborit a dirigé la revue d'Agressologie de 1958 à 1983.
		On doit à Laborit l'introduction (1952) de la chlorpromazine (le premier neuroleptique, dont le nom commercial est Largactil) dans le traitement de la schizophrénie.
	fr.wikipedia.org /wiki/Henri_Laborit (447 words)

	Drugs and the Brain: Antipsychotics
		Henri Laborit, a French physician, was using chlorpromazine as a medication to decrease anxiety before surgery.
		Noting the calming effect of this drug on patients, he suggested that it might be useful in the treatment of mental illness.
		In Paris in 1951, Laborit tested his theory by administering chlorpromazine to psychotic patients, with striking results.
	www.csusm.edu /DandB/Antipsychotics.html (1141 words)

	GHB: The Story Behind the Story
		A decade earlier, Laborit had demonstrated that the drug chlorpromazine (sold in the US as Thorazine®) could be used to suppress the symptoms
		For his pioneering work with chlorpromazine, Professor Laborit was nominated for the Nobel Prize.
		In the four decades since GHB was discovered, Laborit and other scientists have thoroughly and systematically explored its role in the biochemistry of humans and other mammals.
	members.tripod.com /~feedback2wk/GHBstory.html (1384 words)

	Online Brochure (Site not responding. Last check: 2007-10-09)
		Before the development of the X-Cell-R8 preparation, Dr. Henri Laborit first discovered that the salt form of the minerals magnesium and potassium, combined with the non-essential amino acid aspartic acid, possessed anti-fatigue properties.
		The new process developed by the scientists chelated the minerals to the amino acid and caused the molecules to form an extremely stable chemical bond.
		Salts such as in the Laborit formulation, have very weak chemical bonds that dissociate or breakdown in acids similar to those found in the stomach.
	www.delches.com /xcellr8/brochure.htm (857 words)

	Eye Weekly - Smoking, sex and suppositories - 06.29.00
		The theories that behavioural scientist Henri Laborit explains in Mon Oncle d'Amérique (1980) may or may not have anything to do with the lives of the characters in the film, who occasionally appear as caged mice.
		Though his first two films gave him the reputation of a weighty auteur, the bulk of his work -- rich with bizarre ruminations and cryptic humour -- suggests Resnais preferred to take the piss.
		When asked by American critic Jonathan Rosenbaum whether the theories of Laborit contradicted those of French intellectual Jacques Lacan, the director confessed, "I know nothing about philosophy, science, biology or anything like that....
	www.eye.net /eye/issue/issue_06.29.00/film/resnais.html (683 words)

	Amazon.fr : Eloge de la fuite: Livres: Henri Laborit (Site not responding. Last check: 2007-10-09)
		" Henri Laborit pose, à la lumière des découvertes biologiques, la question de notre libre arbitre, de notre personnalité même. La politique, la société, tout prend dès lors une autre dimension.
		Le Professeur Laborit éclaire le comportement humain avec une grille d'analyse jusqu'ici délaissée par les sciences sociales : la grille biologique.
		le propos de laborit eclaire sous un jour completement nouveau tout ce qui concerne nos relations aux autres et à nous même. la vision que l'on peut avoir de son libre arbitre en est completement bouleversée.
	www.amazon.fr /Eloge-fuite-Henri-Laborit/dp/2070322831 (834 words)

	Mon Oncle d’Amérique (My American Uncle/ My Uncle from America) Film Review - Time Out Film
		Then it introduces its fourth major character, Henri Laborit, a bona fide behavioural scientist, who discusses his theories of biological and emotional triggers.
		Shortsighted critics seem to imagine that the fictional material merely illustrates what Laborit says, although Resnais inserts some jokey shots of 'human' mice to demolish any such notions.
		His triumph is to create a new kind of fiction: a drama that not only leaves room to think, but opens up fissures that thoughts flood into, some prompted by Laborit, others by personal reflections, yet others by dreams.
	www.timeout.com /film/73434.html (209 words)

	Testing Your Vision
		But rarely do we seek to understand 'who we are' through inquiry into 'how do we come to know who we are', and that is the topic of inquiry of this essay.
		In our western scientific culture in particular, as noted by Laborit, we tend to brush over questions of the quality of our 'lenses of inquiry', ignoring how our own dynamic is tied up with the dynamic of what we are observing, and this is leading to aberrant thinking and dysfunctional practice,...
		We need to test our vision in such a manner that we overcome the complaint of Henri Laborit,...
	www.goodshare.org /seetest.htm (3093 words)

	[No title] (Site not responding. Last check: 2007-10-09)
		It was first synthesized in 1964 by French researcher Henri Laborit as a GABA analogue that could more readily cross the blood brain barrier (BBB) so he could study the effects of introduction of GABA into the brain.
		He quickly realized that the substance had a distinct array of physiological and psychological actions that was not describable by a simple GABA agonist model.
		Gallimberti's study from that year on its uses in treating alcohol withdrawal in humans notes that "GHB's action...seems to be without serious side effects." His almost off-hand reference to the "safety of GHB" shows how well-established this property of the nutrient had become.
	sulcus.berkeley.edu /mcb/165_001/papers/manuscripts/_143.html (2395 words)

	All-Time 100 Best Movies by Time Magazine
		Mon oncle d'Amérique, written by Jean Gruault, is a science lesson, given by the biologist Henri Laborit, that is made lucid and entertaining by illustrative skits featuring three characters (Roger-Pierre, Gérard Depardieu, Nicole Garcia) and a lab full of white mice.
		Laborit's questions about the impact of behavioral codes in inhibiting man’s so-called free will dovetail elegantly with Resnais's and Gruault's mission to overthrow the codes of film behavior.
		This is a story of the "civilizing" of the West through two agents: one coolly mechanical (the railroad), the other warmly human (Claudia Cardinale, representing womanhood at its most nurturing and radiant).
	www.filmsite.org /timemagazinegreats4.html (1473 words)

	Cancer, inhibition d'action et Henri Laborit (via CobWeb/3.1 planetlab2.isi.jhu.edu) (Site not responding. Last check: 2007-10-09)
		Cancer, inhibition d'action et Henri Laborit (via CobWeb/3.1 planetlab2.isi.jhu.edu)
		Par la suite, Henri Laborit a découvert que la mémoire d'une action gratifiante n'utilise pas les mêmes voies centrales, ni les mêmes médiateurs que celles d'une punition.
		Les découvertes scientifiques de Laborit, trop complexes pour être présentées ici, permettent de comprendre que, pratiquement l'essentiel des accidents physiopathologiques est sous la dépendance des rapports entre l'individu et son environnement, particulièrement social.
	www.alasanteglobale.com.cob-web.org:8888 /laborit.html (701 words)

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