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Topic: Hepatocyte

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	Hepatocyte lineage cells derived from pluripotent stem cells - Patent 6458589
		Another embodiment of the invention is a differentiated cell having characteristics of a cell of the hepatocyte lineage, which is either harvested from a differentiated cell population of this invention, or is the progeny of a cell harvested from such a population.
		The terms "hepatocyte lineage" cell, "hepatoblastoid" cell and "hepatoembryoid" cell may be used in reference to the differentiated cells of this invention, obtained by differentiating pluripotent cells in the manner described.
		In particular embodiments of this invention, the hepatocyte differentiation agent and the hepatocyte maturation factor are used simultaneously or sequentially.
	www.freepatentsonline.com /6458589.html (16857 words)

	Increased Rates of Liver Cell Death in HCV/HIV Coinfection
		Fas-mediated hepatocyte apoptosis is involved in the pathogenesis of hepatitis C virus (HCV) infection.
		In addition, the irreversible apoptosis of hepatocytes, as assessed by staining of caspase-cleaved cytokeratin 18 filaments, was independently related to the expression of Fas on hepatocytes.
		Fas-stained hepatocytes distributed diffusely were more frequently found in older patients, those with a longer duration of HCV infection, those with lower CD4+ cell nadirs, and those with liver fibrosis.
	www.natap.org /2005/HCV/100505_05.htm (2673 words)

	BioMed Central \| Full text \| Hepatocyte and keratinocyte growth factors and their receptors in human lung emphysema
		Hepatocyte and keratinocyte growth factors are key growth factors in the process of alveolar repair.
		Hepatocyte and keratinocyte growth factors, c-met and keratinocyte growth factor receptor mRNA levels were similar in emphysema and non-emphysema patients.
		The expression of hepatocyte and keratinocyte growth factors and their receptors is preserved in patients with lung emphysema as compared to patients without emphysema.
	www.biomedcentral.com /1471-2466/5/13 (3902 words)

	BioCarta - Charting Pathways of Life
		The hepatocyte growth factor receptor, also called c-Met, is activated by HGF and stimulates proliferation of hepatocytes and other cell types.
		Sustained activation of extracellular signal-regulated kinase stimulated by hepatocyte growth factor leads to integrin alpha 2 expression that is involved in cell scattering.
		Hepatocyte growth factor inhibits anoikis by induction of activator protein 1-dependent cyclooxygenase-2.
	www.biocarta.com /pathfiles/h_metPathway.asp (965 words)

	Recombinant Human Hepatocyte Growth Factor - CYT-244
		Hepatocyte Growth Factor (HGF) is a multifunctional growth factor which regulates both cell growth and cell motility.
		Adenoviral-mediated gene expression of hepatocyte growth factor prevents postoperative peritoneal adhesion in a rat model.
		In vivo hepatocyte growth factor gene transfer to bladder smooth muscle after bladder outlet obstruction in the rat: a morphometric analysis.
	www.prospec.co.il /~prospec/cart/catalog/rHuHGF.html (447 words)

	Hepatocyte - Wikipedia, the free encyclopedia
		The dark structure with a dense core is a peroxisome.
		Histology at BU 22101ooa - "Ultrastructure of the Cell: hepatocytes and sinusoids"
		Hepatocyte, Space of Disse, Kupffer cell, Liver sinusoid, Hepatic stellate cell, Hepatic lobule)
	en.wikipedia.org /wiki/Hepatocyte (601 words)

	The Use of Human Hepatocyte Cultures to Study the Induction of Cytochrome P-450 -- Kostrubsky et al. 27 (8): 887 -- ...
		Hepatocytes prepared from donor HH1 were treated for 48 h with 1.0, 4.0, 10, 15, 20, and 30 µM Taxol, 10 µM rifampicin, or 2 mM phenobarbital.
		Hepatocytes prepared from donors indicated in the figure were either left untreated for 24 or 96 h after plating or treated for 48 h with 4 µM Taxol.
		Hepatocytes prepared from donors indicated in the figure were either left untreated for 24 or 96 h after plating or treated for 48 h with 10 µM rifampicin.
	dmd.aspetjournals.org /cgi/content/full/27/8/887 (4915 words)

	Novel hepatocyte growth factor/scatter factor isoform transcripts in the macaque endometrium and placenta -- Lindsey ...
		Chen, C., Spencer, T.E. and Bazer, F.W. (2000) Expression of hepatocyte growth factor and its receptor c-met in the ovine uterus.
		Lail-Trecker, M., Fulati, R. and Peluso, J.J. (1998) A role for hepatocyte growth factor/scatter factor in regulating normal and neoplastic cells of reproductive tissues.
		(1994) Hepatocyte growth factor and its variant with a deletion of five amino acids are distinguishable in their biological activity and tertiary structure.
	molehr.oxfordjournals.org /cgi/content/full/8/1/81 (3686 words)

	Medical Dictionary: Hepatocyte growth factor - WrongDiagnosis.com
		Hepatocyte growth factor: Multifunctional growth factor which regulates both cell growth and cell motility.
		It exerts a strong mitogenic effect on hepatocytes and primary epithelial cells.
		Hepatocyte growth factor : newly identified and characterized growth factor; involved in regulating cell migration.
	www.wrongdiagnosis.com /medical/hepatocyte_growth_factor.htm (219 words)

	Stem cell factor restores hepatocyte proliferation in IL-6 knockout mice following 70% hepatectomy -- Ren et al. 112 ...
		Primary mouse hepatocyte proliferation in vitro in response to SCF.
		Primary mouse hepatocytes were exposed to increasing doses of SCF from 0 to 100 ng/ml and proliferation was measured after 24 and 48 hours of incubation.
		Enhanced hepatocyte proliferation in response to SCF in IL-6 knockout mice is stat3-mediated.
	www.jci.org /cgi/content/full/112/9/1407 (7105 words)

	Fibronectin-Mediated Hepatocyte Shape Change Reprograms Cytochrome P450 2C11 Gene Expression via an Integrin-Signaled ...
		Hepatocytes were isolated and cultured without fibronectin and cells and culture medium collected at various times.
		Hepatocyte spreading is presented as the percentage of 200 hepatocytes in each treatment group that had spread to at least twice the diameter of hepatocytes cultured without fibronectin.
		Albumin mRNA abundance in hepatocytes cultured with fibronectin and the degradation of in vitro transcribed CYP2C 11 and albumin mRNAs.
	molpharm.aspetjournals.org /cgi/content/full/58/5/976 (3369 words)

	BioMed Central \| Full text \| Met-Independent Hepatocyte Growth Factor-mediated regulation of cell adhesion in human ... (Site not responding. Last check: 2007-10-13)
		One stromally-derived factor, Hepatocyte Growth Factor (HGF), was found twenty years ago to regulate invasion and growth of carcinoma cells.
		Indeed, the list of factors involved in bi-directional epithelial-stromal cell interactions is long, with representatives from many growth factor families, and includes Hepatocyte Growth Factor (HGF) [11], a subject of this study.
		Hepatocyte Growth Factor (HGF) and all other chemicals were purchased from Sigma (St. Louis, MO).
	www.biomedcentral.com /1471-2407/6/197 (6899 words)

	Nonviral gene transfer of hepatocyte growth factor attenuates neurologic injury after spinal cord ischemia in rabbits ...
		Nonviral gene transfer of hepatocyte growth factor attenuates neurologic injury after spinal cord ischemia in rabbits -- Shi et al.
		Nonviral gene transfer of hepatocyte growth factor attenuates neurologic injury after spinal cord ischemia in rabbits
		Hepatocyte growth factor is a potent angiogenic and
	jtcs.ctsnetjournals.org /cgi/content/abstract/132/4/941 (393 words)

	Hepatocyte growth factor gene therapy accelerates regeneration in cirrhotic mouse livers after hepatectomy -- Xue et ...
		Hepatocyte growth factor gene therapy of liver cirrhosis in rat.
		Hepatocyte growth factor and its variant with a deletion of five amino acids are distinguishable in their biological activity and tertiary structure.
		Hepatocyte growth factor suppresses the onset of liver cirrhosis and abrogates lethal hepatic dysfunction in rats.
	gut.bmj.com /cgi/content/full/52/5/694 (4580 words)

	Is Hepatocyte Growth Factor a Protein With Cardioprotective Activity in the Ischemic Heart? -- Schaper and Kubin 95 ...
		Stimulation of DNA synthesis in primary cultures of adult rat hepatocytes by platelet-associated substance(s).
		Hepatocyte growth factor (HGF) stimulates the tyrosine kinase activity of the receptor encoded by the proto-oncogene c-Met.
		Tumorigenicity of the met proto-oncogene and the gene for hepatocyte growth factor.
	circ.ahajournals.org /cgi/content/full/95/11/2471 (1661 words)

	Cathepsin B inactivation attenuates hepatocyte apoptosis and liver damage in steatotic livers after cold ischemia-warm ...
		Cathepsin B inactivation attenuates hepatocyte apoptosis and liver damage in steatotic livers after cold ischemia-warm reperfusion injury -- Baskin-Bey et al.
		Hepatocyte ischemia and apoptosis occur adjacent to central veins in steatotic livers after CI/WR injury.
		Cathepsin B knockout mice are resistant to tumor necrosis factor-alpha-mediated hepatocyte apoptosis and liver injury: implications for therapeutic applications.
	ajpgi.physiology.org /cgi/content/full/288/2/G396 (4230 words)

	Advances in hepatocyte transplantation: a myth becomes reality -- Lee 108 (3): 367 -- Journal of Clinical Investigation (Site not responding. Last check: 2007-10-13)
		hepatocytes bear the brunt of repopulating the liver.
		Hepatocyte transplantation involves the transfer of normal hepatocytes
		Braun, K.M., Degen, J.L., and Sandgren, E.P. Hepatocyte transplantation in a model of toxin-induced liver disease: variable therapeutic effect during replacement of damaged parenchyma by donor cells.
	www.jci.org /cgi/content/full/108/3/367 (1624 words)

	Chemicon - Product #GF116 - Hepatocyte Growth Factor, recombinant human [HGF]
		Human Hepatocyte Growth Factor (HGF) is also known as Scatter Factor and Hepatopoeitin A. HGF is a potent mitogen for mature parenchymal hepatocyte cells and acts as a growth factor for a broad spectrum of tissues and cell types.
		GF116 is an 80 kDa disulfide-linked heterodimeric protein consisting of the alpha chain (463 amino acids, 69kDa reducing conditions) and the beta chain (234 amino acids, 34kDa).
		GF116 is an 80 kDa disulfide-linked heterodimeric protein consisting of the alpha chain (463 amino acids) and the beta chain (234 amino acids).
	www.chemicon.com /browse/productdetail.asp?ProductID=GF116 (315 words)

	The Forkhead Box m1b transcription factor is essential for hepatocyte DNA replication and mitosis during mouse liver ...
		The Forkhead Box m1b transcription factor is essential for hepatocyte DNA replication and mitosis during mouse liver regeneration -- Wang et al.
		The mean of the number of BrdUrd-positive hepatocyte nuclei per 1,000 hepatocytes ± SE was calculated for each time point (three mice per time point).
		Hepatocyte mitosis is expressed as the mean of the number of mitotic figures found per 1,000 hepatocytes ± SD using three mice per time point (10, 25).
	www.pnas.org /cgi/content/full/99/26/16881 (5068 words)

	Isolated Hepatocyte Transplantation in an Infant With a Severe Urea Cycle Disorder -- Horslen et al. 111 (6): 1262 -- ...
		E, Hepatocyte infusions: bars represent the day of infusions and the number of viable hepatocytes infused on each occasion.
		Transplanted hepatocytes were infused via a catheter placed in the umbilical vein.
		Hepatocytes corrected by gene therapy are selected in vivo in a murine model of hereditary tyrosinaemia type I [see comments] [published erratum appears in Nat Genet 1996 Apr;12:458].
	pediatrics.aappublications.org /cgi/content/full/111/6/1262 (3191 words)

	Bile Acid Regulation of Hepatic Physiology: I. Hepatocyte transport of bile acids -- Wolkoff and Cohen 284 (2): 175 -- ...
		rat hepatocytes and during rat liver regeneration (18).
		The concentration gradient of bile acids between the hepatocyte and the bile canaliculus is large.
		Down-regulation by extracellular ATP of rat hepatocyte organic anion transport is mediated by serine phosphorylation of oatp1.
	ajpgi.physiology.org /cgi/content/full/284/2/G175 (2910 words)

	Embolization of Portal Vein Branches Induces Hepatocyte Replication in Swine: A Potential Step in Hepatic Gene Therapy ...
		Hepatocyte replication was assessed by measuring the fraction
		The time course of hepatocyte replication in a series of pigs was assessed as described in Materials and Methods.
		The long-term consequences of the induction of hepatocyte replication
	radiology.rsnajnls.org /cgi/content/full/210/2/467 (6589 words)

	Gene transfection of hepatocyte growth factor attenuates reperfusion injury in the heart -- Ueda et al. 67 (6): 1726 -- ... (Site not responding. Last check: 2007-10-13)
		Gene transfection of hepatocyte growth factor attenuates reperfusion injury in the heart -- Ueda et al.
		Gene transfection of hepatocyte growth factor attenuates reperfusion injury in the heart
		Hepatocyte growth factor is upregulated by low-density lipoproteins and inhibits endothelin-1 release
	ats.ctsnetjournals.org /cgi/content/abstract/67/6/1726 (1101 words)

	Hepatocyte Growth Factor/Met System Promotes Endometrial and Endometriotic Stromal Cell Invasion via Autocrine and ... (Site not responding. Last check: 2007-10-13)
		Khan KN, Masuzaki H, Fujishita A, Kitajima M, Sekine I, Ishimaru T 2003 Immunoexpression of hepatocyte growth factor and c-Met receptor in the eutopic endometrium predicts the activity of ectopic endometrium.
		Ito M, Harada T, Tanikawa M, Fujii A, Shiota G, Terakawa N 2001 Hepatocyte growth factor and stem cell factor involvement in paracrine interplays of theca and granulosa cells in the human ovary.
		Interleukin-6- and tumour necrosis factor {alpha}-mediated expression of hepatocyte growth factor by stromal cells and its involvement in the growth of endometriosis
	jcem.endojournals.org /cgi/content/full/89/2/823 (6394 words)

	Early Postnatal Dexamethasone Decreases Hepatocyte Growth Factor in Tracheal Aspirate Fluid From Premature Infants -- ...
		Early Postnatal Dexamethasone Decreases Hepatocyte Growth Factor in Tracheal Aspirate Fluid From Premature Infants -- Lassus et al.
		Molecular cloning and expression of human hepatocyte growth factor.
		Gohda E, Matsunaga T, Kataoka H, Takebe T, Yamamoto I. Induction of hepatocyte growth factor in human skin fibroblasts by epidermal growth factor, platelet-derived growth factor and fibroblast growth factor.
	pediatrics.aappublications.org /cgi/content/full/110/4/768 (2919 words)

	Vascular Origin of a Soluble Truncated Form of the Hepatocyte Growth Factor Receptor (c-met) -- Wajih et al. 90 (1): 46 ...
		Hepatocyte growth factor (scatter factor) is an angiogenic growth
		The shedding of soluble c-met was induced by the ligand, hepatocyte
		Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth.
	circres.ahajournals.org /cgi/content/full/90/1/46 (4491 words)

	Involvement of hepatocyte growth factor/scatter factor and Met receptor signaling in hair follicle morphogenesis and ...
		Involvement of hepatocyte growth factor/scatter factor and Met receptor signaling in hair follicle morphogenesis and cycling -- LINDNER et al.
		Involvement of hepatocyte growth factor/scatter factor and Met receptor signaling in hair follicle morphogenesis and cycling
		Longati, P., Albero, D., Comoglio, P. (1996) Hepatocyte growth factor is a pleiotropic factor protecting epithelial cells from apoptosis.
	www.fasebj.org /cgi/content/full/14/2/319 (8016 words)

	Transforming Growth Factor {alpha} Levels in Liver and Blood Correlate Better than Hepatocyte Growth Factor with ...
		Ishiki Y, Ohnishi H, Muto Y, Matsumoto K, Nakamura T: Direct evidence that hepatocyte growth factor is a hepatotropic factor for liver regeneration and has a potent antihepatitis effect in vivo.
		Schirmacher P, Geerts A, Pietrangelo A, Dienes HP, Rogler CE: Hepatocyte growth factor/hepatopoietin A is expressed in fat-storing cells from rat liver but not myofibroblast-like cells derived from fat-storing cells.
		Lindroos P, Zarnegar R, Michalopoulos GK: Hepatocyte growth factor (hepatopoietin A) rapidly increases in plasma before DNA synthesis and liver regeneration stimulated by partial hepatectomy and carbon tetrachloride administration.
	ajp.amjpathol.org /cgi/content/full/153/3/955 (3642 words)

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