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| | Vertically Acquired HCV: natural history |
 | | Hepatomegaly, the only clinical sign reported, was found in 10% of children and was significantly associated with a high proportion of abnormal alanine transaminase (ALT) levels (adjusted odds ratio [OR], 4.17; 95% confidence interval [CI], 1.67-10.42; P =.002). |
 | | Although hepatomegaly was observed in only a minority of children, it was significantly associated with a high proportion of abnormal ALT levels. |
 | | Hepatomegaly, viremia, and high ALT levels were found to be indicative of active infection in the same children, and low viral activity early in life was associated with clearance later on. |
| www.natap.org /2005/HCV/060605_04.htm (2622 words) |
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