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Topic: Herpes simplex virus

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  Herpes Simplex Viruses
It is not certain whether the virus had recently arrived in the brain from a state of latency in a sensory ganglion or that the virus is already present in a latent state in the brain.
HSV is spread by contact, as the virus is shed in saliva, tears, genital and other secretions, By far the most common form of infection results from a kiss given to a child or adult from a person shedding the virus.
For determination of intrathecal HSV Ab synthesis, the integrity of the blood-brain barrier should be assessed to ensue that any HSV Ab present in the CSF is not a result of transudation from the serum across a compromised blood-brain barrier to the CSF, as is the case during the early stages of acute necrotizing encephalitis.
virology-online.com /viruses/HSV.htm   (5283 words)

 Herpes Simplex Virus
Herpes infects the nerve cells of the spinal cord in the pelvic region (as is the case for genital herpes) and of the nerve ganglia in the facial region at the base of the brain (as is the case for oral herpes).
Herpes is a DNA-type virus, inserting its DNA directly into the nerve endings of the skin, which then leads along nerve fibers to the nucleus of the nerve cell.
The virus may be transmitted to the penis, the vagina, the rectum, the mouth, and more rarely, the esophagus, the trachea, and even onto broken areas of skin that may appear anywhere on the body.
www.herpesonline.org /articles/herpes_simplex_virus.html   (1694 words)

 Herpes simplex virus - Wikipedia, the free encyclopedia
The herpes simplex virus (HSV) (also known as cold sore, night fever, or fever blister) is a virus that manifests itself in two common viral infections, each marked by painful, watery blisters in the skin or mucous membranes (such as the mouth or lips) or on the genitals.
When not symptomatic HSV lies dormant in the bodies of the nerve cells, replicating within the axons towards the skin during an outbreak.
HSV is generally transmitted by direct contact of lips and/or genitals when the sores are present, or just before they appear (known as shedding).
en.wikipedia.org /wiki/Herpes_simplex_virus   (591 words)

 Herpes Simplex Virus
Herpes infections in infants and in people who have weak immune systems or herpes infections that affect the eyes are serious and potentially life-threatening.
Herpes cannot be cured, so the goals of treatment include reducing the number of recurrences and lessening your symptoms when you have an outbreak.
Herpes viruses can be transmitted to a newborn during vaginal delivery in mothers infected with herpes viruses, especially if the mother has active lesions in the vagina at the time of delivery.
www.umm.edu /altmed/ConsConditions/HerpesSimplexViruscc.html   (3339 words)

 Postgraduate Medicine: Herpes simplex virus infections
Most cases of herpes simplex infection are recognized by the morphologic characteristics of the disease (small, grouped vesicles on erythematous bases, which then become pustules, umbilicate, and later crust) (figure 4: not shown).
The virus is recovered from the cerebrospinal fluid in 25% to 40% of patients, and polymerase chain reaction (PCR) studies are used to diagnose disease in culture-negative patients.
Herpes simplex encephalitis occurs in immunocompetent patients, but the risk of disseminated disease tends to be increased in immunocompromised patients (5,6).
www.postgradmed.com /issues/2000/03_00/nadelman.htm   (3603 words)

 eMedicine - Herpes Simplex Virus Infection : Article by Sherman Alter, MD   (Site not responding. Last check: 2007-10-16)
The biologic properties of HSV that control the course of infection are neuroinvasiveness (the ability of the virus to invade the brain), its neurotoxicity (its ability to multiply and destroy the brain), and its latency (its ability to remain in a nonreplicating form in the dorsal root ganglia of the CNS).
HSV encephalitis may be a manifestation of primary or recurrent infection with the virus.
An intact vesicle is aspirated with a sterile tuberculin syringe.
www.emedicine.com /ped/topic995.htm   (8816 words)

 Herpes definition - Womens Health and Medical Information on MedicineNet.com
Herpes simplex type 1, also known as human herpesvirus 1 (HHV-1), causes cold sores and fever blisters in the mouth and around it.
Both herpes simplex types 1 and 2 are capable of causing systemic disease including encephalitis (infection of the brain) in someone who is immunodeficient.
Genital Herpes In Women - Genital herpes, a viral infection by the herpes simplex virus (HSV), is transmitted during sexual contact with the mucous-covered linings of the mouth, vagina, or the genital skin.
www.medterms.com /script/main/art.asp?articlekey=11468   (353 words)

 Herpes simplex - Wikipedia, the free encyclopedia
Herpes simplex encephalitis is a very serious disorder, thought to be caused by the retrograde transmission of the virus from a peripheral site to the central nervous system along a nerve axon.
It is known that the virus lies dormant in the ganglion of the trigeminal or fifth cranial nerve.
The herpes virus is a double-stranded DNA (dsDNA)-type virus.
en.wikipedia.org /wiki/Herpes   (4974 words)

 Cornea Associates of Texas - Eye Information - Herpes Simplex Virus
Herpes simplex virus (HSV) is a member of the family Herpes- viridae.
HSV diagnosis is usually based on history and typical clinical appearance on examination.
HSV is usually treated with topical medications, such as triflourothymidine or vidarabidine; sometimes, it may require anti-viral agents and topical steroids that are.
www.corneatexas.com /html/eye_info_herpes.html   (642 words)

 MedlinePlus Medical Encyclopedia: Herpes simplex
Herpes simplex is an infection that primarily affects the mouth or genital area.
Herpes simplex virus type 1 (HSV-1) is usually associated with infections of the lips, mouth, and face.
In addition to oral and genital lesions, the virus can also lead to complications such as meningoencephalitis (infection of the lining of the brain and the brain itself) or cause infection of the eye -- in particular the conjunctiva, and cornea.
www.nlm.nih.gov /medlineplus/ency/article/001324.htm   (866 words)

 Glossary of Terms for Genital Herpes
Herpes simplex virus (HSV): A virus that can cause blisters on the skin or mucous membranes (mouth or lips) above the waist and in the other by such blisters on the genitals.
Herpes simplex virus type 1 (HSV-1): A herpes virus that usually causes cold sores and fever blisters in and around the mouth.
Herpes simplex virus type 2 (HSV-2): A herpes virus that usually causes genital herpes, which is characterized by sores in the genital area.
www.famvir.com /info/tools/glossary/glossary.jsp   (439 words)

 Herpes Simplex Virus (HSV) - DermatologyChannel
Herpes simplex viruses HSV-1 and HSV-2 cause outbreaks on the skin and mucous membranes.
While the virus can persist on surfaces such as towels or toilet seats for as long as 60 minutes, it is extremely unusual for an infection to result from contact with these surfaces.
Treatment for herpes simplex is not necessary because it is self-limiting.
www.dermatologychannel.net /viral_infection/hsv.shtml   (631 words)

 Herpes Simplex Virus (HSV)
HSV is a member of the family of viruses responsible for chicken pox, shingles, and infectious mononucleosis.
The virus which causes herpes lives in nerve cells at the bottom of the spine, and “creeps” to the surface once in a while to cause sores and blisters.
The group at highest risk are women who acquire HSV late in their pregnancy, particularly those who have no immune defense to the virus (developed from having had diseases like chickenpox, or cold sores, etc.).
www.healthsquare.com /fgwh/wh1ch11p4.htm   (1939 words)

 The Big Picture Book of Viruses - Herpesviruses
Two herpes virus particles are shown; they were prepared for transmission electron microscopy by the negative stain technique from the Wadsworth Center of the New York State Department of Health.
Herpes simplex virus, the causative agent of fever blisters.
Herpes simplex virus infection becomes latent, that is it becomes invisible after a fever blister episode, but the virus persists, in ganglia at the floor of the brain, where when conditions are right it can re-emerge.
www.virology.net /Big_Virology/BVDNAherpes.html   (771 words)

HSV infection appears to be a 'wasteful' process, only ~25% of viral DNA/protein produced is incorporated into virions.
Latent virus is reactivated and AIDS/transplant patients experience frequent and severe infections with the potential for involvement of many possible organs.
Discovery of the virus solved a longstanding mystery - primary infection in childhood causes "roseola infantum" a.k.a.
www.tulane.edu /~dmsander/WWW/335/Herpesviruses.html   (1883 words)

 DermAtlas: Online Dermatology Image Library dermatology image,whitlow,Herpes simplex virus infection   (Site not responding. Last check: 2007-10-16)
The lesion on his sacrum grew Herpes Simplex Virus-1 and the lesion on his scrotum grew Herpes Simplex Virus-2.
Herpes Simplex Virus and Varicella Zoster Virus show similar viral cytopathic effect, and cannot be reliably distinguished on histology.
A smear from the base of a blister showed multinucleated giant cells typical of Herpes virus infection and serologic studies were positive for Herpes simplex virus type II.
dermatlas.med.jhmi.edu /derm/result.cfm?Diagnosis=199   (878 words)

However, either virus can infect any area of the body that is covered by a “mucous membrane”, such as the skin found in the mouth, rectum, eyes, throat, vagina.
Secondary herpes is so-called because it is a reactivation of herpes that is lying dormant in the nerve cells.
Herpes is transmitted in bodily fluids, and while this is most likely when one has open ulcers, the virus can also be present without any other symptoms.
www.vpul.upenn.edu /ohe/HealthLinks/herpes.htm   (377 words)

 eMedicine - Herpes Simplex : Article by Rahul Sharma, MD, MBA   (Site not responding. Last check: 2007-10-16)
Infection by HSV requires a break in the skin's barrier; intact skin is resistant to the virus.
Herpes viruses cause cytolytic infections; therefore, pathologic changes are due to cell necrosis as well as inflammatory changes.
Since HSV remains latent in sensory ganglia, the rates of relapse are similar in treated and untreated patients.
www.emedicine.com /emerg/topic246.htm   (2547 words)

 An Acclaimed Herpes Information Resource, www.herpes.com, Information About Sexually Transmitted Dieases (special ...   (Site not responding. Last check: 2007-10-16)
Oral herpes, an infection caused by the herpes simplex virus, is estimated to be present in 50 to 80 percent of the American adult population.
20 percent, over 50 million people, are infected with genital herpes, also caused by the herpes simplex virus, and the majority of these cases may be unaware they even have it.
Until an effective herpes vaccine or cure for HSV infection is found, the prevailing approach to treatment continues to be suppressive antiviral therapy.
www.herpes.com.cob-web.org:8888   (462 words)

 [No title]
Herpes on the mouth is easily spread through kissing.
The virus can be spread even if you don't have blisters.
For more information on herpes, call the HELP line in Atlanta at 404-294-6364 or the National Herpes Hotline at 919-361-8488.
www.hiv.va.gov /vahiv?page=diag-04-03-07   (103 words)

 Dr. Edward K. Wagner's Herpes Virus Research
HSV is a nuclear replicating, icosahedral, enveloped DNA virus.
Herpes simplex virus genome must enter the cell for the initiation of infection.
Final release of the enveloped virion from the cell involves the virus being incorporated into exocytotic vesicles then released from the cell as free infectious virus.....
darwin.bio.uci.edu /~faculty/wagner/movieindex.html   (252 words)

 Dr. Edward K. Wagner's Herpes Virus Research
Herpes simplex virus is a highly adapted human pathogen with rapid lytic replication cycle, and yet with the ability to invade sensory neurons where highly restricted gene expression occurs with the absence of cytopathology.
The analysis of the pattern of HSV transcription has been a major goal of this laboratory for over thirty (30) years.
Of particular interest are those features of the HSV genome and its interaction with the neuronal cell which lead to latency and reactivation.
darwin.bio.uci.edu /~faculty/wagner/hsvresrch.html   (382 words)

 Genital Herpes - STD information from CDC
Genital herpes is a sexually transmitted disease (STD) caused by the herpes simplex viruses type 1 (HSV-1) and type 2 (HSV-2).
Although the infection can stay in the body indefinitely, the number of outbreaks tends to decrease over a period of years.
Genital herpes — Initial visits to physicians' offices: United States, 1966—2004 (Figure 39)
www.cdc.gov /std/Herpes   (223 words)

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