
	Where results make sense

Topic: Heterotopic ossification

In the News (Fri 17 Feb 12)

EXECUTIVE POWER

Iran

ANALYSIS

Pakistan

Family compact

	SPINALCORD: Heterotopic Ossification - SCI InfoSheet #12
		Heterotopic ossification (HO) is the development of bone in abnormal areas, usually in soft tissues.
		The incidence rate of heterotopic ossification in individuals with spinal cord injury is approximately 16 to 53 percent.
		Heterotopic ossification may occur anywhere in the body but is most frequently found around the joints or long bones.
	www.spinalcord.uab.edu /show.asp?durki=21485 (2039 words)

	Joint Program in Nuclear Medicine
		Heterotopic ossification is a phenomenom in which new bone is formed in tissue that do not normally ossify.
		Heterotopic ossification is the associated with many other disease entities and various forms of trauma including head injury, and traumatic or surgical insult.
		When the extent of heterotopic ossification is of such magnitude that limitation of joint motion occurs, heterotopic ossification may interfere with activities of daily living such as sitting and dressing of the lower extremities or cause abnormal skin pressure areas.
	www.med.harvard.edu /JPNM/TF93_94/Dec7/WriteUpDec7.html (872 words)

	Dorlands Medical Dictionary (Site not responding. Last check: 2007-10-13)
		ossification that occurs in and replaces connective tissue, as occurs in the calvaria and in periosteal bone formation.
		cu´tis progressive dermal ossification during childhood, with development of hard, round to irregular nodules representing islands of heterotopic bone within the dermis or subcutis, followed by coalescence of the lesions into plaques, and later by invasion of ossification into deep connective tissues.
		It may be sporadic or inherited as an autosomal dominant trait; the affected gene encodes a subunit of the G protein stimulating adenylyl cyclase.
	www.mercksource.com /pp/us/cns/cns_hl_dorlands.jspzQzpgzEzzSzppdocszSzuszSzcommonzSzdorlandszSzdorlandzSzdmd_o_08zPzhtm (3314 words)

	Heterotopic Ossification - MedPix Medical Image Database and Teaching Files
		Heterotopic ossification is a phenomenon in which new bone is formed in tissue that does not normally ossify.
		Heterotopic ossification is associated with many disease entities and various forms of trauma, including head and spinal cord injury, and traumatic or surgical insult.
		When the extent of heterotopic ossification is of such magnitude that limitation of joint motion occurs, heterotopic ossification may interfere with activities of daily living such as sitting, and dressing of the lower extremities.
	rad.usuhs.mil /medpix/master.php3?mode=single&recnum=6422&th=-1 (529 words)

	Colchicine inhibits heterotopic ossification: experimental study in rabbits.
		Heterotopic ossification is a common complication of hip surgery and musculoskeletal or brain trauma.
		Heterotopic ossification was induced in three groups of New Zealand white rabbits (females, 6 months old, weight 3-3.5 kg) by injecting 2 ml bone marrow drawn from the iliac crest into their right thigh muscle.
		The role of colchicine in preventing heterotopic ossification in other bone-forming conditions, such as hip arthroplasty or pelvic trauma, and after brain trauma, remains to be evaluated in a clinical setting.
	www.galenicom.com /medline/article/15658143/au:Dudkiewicz+I (332 words)

	Didronel , Didronel Side Effects, Didronel Information
		Heterotopic ossification, also referred to as myositis ossificans (circumscripta, progressiva or traumatica), ectopic calcification, periarticular ossification, or paraosteoarthropathy, is characterized by metaplastic osteogenesis.
		Heterotopic ossification may occur for no known reason as in myositis ossificans progressiva or may follow a wide variety of surgical, occupational, and sports trauma (e.g.
		Heterotopic ossification complicating total hip replacement typically develops radiographically 3 to 4; weeks postoperatively in the pericapsular area of the affected hip joint.
	www.medisave.ca /DrugMoreInfo363.aspx (916 words)

	Current concepts in the development of heterotopic ossification Journal of Bone and Joint Surgery - Find Articles
		The development of heterotopic ossification has been shown to be associated with many predisposing factors including neurological injury, both to the spinal cord and the brain, major joint surgery and burns.1-4 Marked variation can occur in the incidence and location of bone formed and in the resulting complications.
		Heterotopic ossification after traumatic brain injury was first reported by Roberts2 who described involvement of the elbow in patients with cerebral injury and a prolonged period of coma.
		Gennarelli10 suggested that diffuse axonal injury may predispose to the development of heterotopic ossification more than focal brain injury, as patients with the former injury tend to be younger, may have a period of coma and often develop limb spasticity.
	www.looksmartrecreation.com /p/articles/mi_qa3767/is_200408/ai_n9440855 (785 words)

	Prevention of heterotopic ossification with irradiation after total hip - Wheeless' Textbook of Orthopaedics
		Sixty-two hips in fifty-five patients who were considered to be at risk for postoperative heterotopic ossification were randomly divided into two groups: one received a single 800-centigray dose of limited-field radiation and the other, 1000 centigray of limited-field radiation in divided doses.
		The risk for heterotopic-bone formation was identified on the basis of previously described criteria, which included previous heterotopic ossification after an operation about the hip, hypertrophic osteoarthritis or post-traumatic osteoarthrosis characterized by formation of extensive osteophytes, radiographic evidence of diffuse idiopathic skeletal hyperostosis, ankylosing spondylitis, and male sex.
		At a minimum six-month follow-up, progression of heterotopic ossification had occurred in seven (21 per cent) of thirty-four hips in the first group and in six (21 per cent) of twenty-eight hips in the second group.
	www.wheelessonline.com /ortho/prevention_of_heterotopic_ossification_with_irradiation_after_total_hip (300 words)

	The Journal of Bone and Joint Surgery
		Mild, grade-I or grade-II, heterotopic ossification was evident in 21% (16/78) of patients in the radiation group and in 21% (15/72) of those in the indomethacin group.
		This rate of heterotopic ossification was significantly higher than the overall rate of prevalence of severe heterotopic ossification in patients who received either prophylaxis regimen (11/150, 7%; p< 0.002) and was also higher than that in either the indomethacin group or the radiation therapy group.
		Considerations that are unique to the more youthful trauma patients with acetabular fracture include the risk of irradiation to the pelvic area in women of childbearing age, the logistical considerations that surround issues of transportation of critically ill patients to a radiation facility, and the long-term risk of malignant transformation in the irradiated field.
	www.jbjs.org /Comments/c_p_pelleg_burd.shtml (928 words)

	Case Report Forum: Heterotopic Ossification Associated with Traumatic Amputation - Journal of Prosthetics and ...
		Heterotopic ossification (HO) is the formation of mature trabecular bone in sites where it is not normally present.
		Heterotopic ossification is most commonly encountered following central nervous system insults (spinal cord injuries and traumatic brain injuries), traumatic violent surgical insults (total hip replacements and acetabular fractures) and burns.
		Chalmers postulated the role of an osteogenic precursor cell; heterotopic ossification is thought to be the result of differentiation of noncirculating pluripotent mesenchymal cells to osteoblast stem cells.
	www.oandp.org /jpo/library/1997_01_033.asp (1965 words)

	sBMJ \| Picture Quiz
		Heterotopic ossification (myositis ossificans) is a frequent complication after injuries around the elbow and consists of abnormal bone and cartilage formation in the soft tissues adjacent to the joint.
		Patients at risk for heterotopic ossification can be treated prophylactically with low dose irradiation (8 to 10 Gy) administered within the first three to four days after operation.
		Ankylosis of joints secondary to heterotopic ossification can be treated by surgical excision after the ossification has matured, as early excision of the mass gives bad results, being almost always followed by massive recurrence.
	www.studentbmj.com /issues/01/08/education/276.php (569 words)

	SurfWax: News, Reviews and Articles On Heterotopic
		In the piggyback, or heterotopic heart transplant, Hannah's new heart was placed in the right side of her chest and attached three ways to her original heart, which was left in position...
		In heterotopic ossification, or H.O., new bone grows where it is not supposed to.
		This abnormal process is called heterotopic ossification, and doctors can't let Bretz get a start on adjusting to a life of standing 6 feet tall again until it subsides.
	news.surfwax.com /health/files/Heterotopic.html (744 words)

	Synostosis Between Pubic Bones due to Neurogenic, Heterotopic Ossification
		Neurogenic, heterotopic ossification is characterised by the formation of new, extraosseous (ectopic) bone in soft tissue in patients with neurological disorders.
		CT of pelvis revealed heterotopic bone lying in close proximity to the balloon of the Foley catheter; the sharp edge of heterotopic bone probably acted like a saw and led to frequent rupture of the balloon of the Foley catheter.
		Since heterotopic bone formation was observed in the pubic region after suprapubic cystostomy and chronic urine leak, it is possible that risk factors related to the urinary tract might have played a role in heterotopic bone formation, which resulted in synostosis between pubic bones.
	www.thescientificworld.com /SCIENTIFICWORLDJOURNAL/toc/TSWJ_ArticleLanding.asp?jid=0&FromPage=Search&ArticleId=2285&navFrom=Search&From=Result&toggleArticleCloud=1 (546 words)

	3810cr3
		Heterotopic ossification represents a biological process that results in new bone tissues that do not, under normal conditions, ossify(1-3).
		Keenan and Kauffman(4) found that in patients with head injury, heterotopic ossification was the most frequent cause of ulnar nerve entrapment, being found in 78% of all elbows.
		Heterotopic ossification was implicated in the etiology of one of these(5).
	www.sma.org.sg /smj/3810/articles/3810cr3.htm (1085 words)

	Heterotopic ossification around the hip with intramedullary nailing of - Wheeless' Textbook of Orthopaedics
		1988 Aug; 28(8): 1207-13 Heterotopic ossification (HO) at the proximal end of a reamed intramedullary femoral nail is a complication of the procedure.
		A study of patients undergoing locked intramedullary nailing of the femur to assess subsequent development of heterotopic ossification at the proximal end of the implant was done.
		Heterotopic bone was graded as: none--32%; minimal--20%, mild--28%; moderate--15%; and severe--5%.
	72.3.142.26 /ortho/heterotopic_ossification_around_the_hip_with_intramedullary_nailing_of (209 words)

	MedFriendly.com: Heterotopic ossification
		The word "heterotopic" means pertaining to heterotopia, an abnormal condition in which an organ or part of the body is out of its normal place.
		In heterotopic ossification, the extra bone that is formed is what is out of place.
		Heterotopic ossification is also known as ectopic ossification, exuberant callus, and myositis ossificans.
	www.medfriendly.com /heterotopicossification.html (437 words)

	PhysicalTherapist.com :: View topic - Information Please (Site not responding. Last check: 2007-10-13)
		Heterotopic ossification is when bone tissue forms in places it shouldn't, like particularly within the joint spaces, thereby preventing a joint from having much movement.
		The chances of getting heterotopic ossification increase with several factors, including being male, having a traumatic generator in addition to the neurological generator (such as in this case), motor vehicle accident, between the ages of 20 and 40-ish, and so on.
		If it is heterotopic ossification at that joint, there is also nothing a physical therapist can do for that joint at this time.
	www.physicaltherapist.com /forum/viewtopic.php?t=1059&view=previous&sid=8984127405054ef7768c0a5fc521c902 (817 words)

	Heterotopic Ossification of the Hip - Wheeless' Textbook of Orthopaedics
		Heterotopic ossification around the hip in spinal cord-injured patients.
		Heterotopic ossification as a complication of acetabular fracture.
		Surgical approaches for resection of heterotopic ossification in traumatic brain-injured adults.
	www.wheelessonline.com /ortho/heterotopic_ossification_of_the_hip (845 words)

	Heterotopic ossification in rehabilitation patients who have had internal fixation of an acetabular fracture (Site not responding. Last check: 2007-10-13)
		Heterotopic ossification (HO) is a common and disabling problem in patients who require rehabilitation.
		Neurogenic heterotopic ossification has been well described in patients with spinal cord injuries (1-3) and in patients with traumatic brain injuries (4-7).
		Relationship of heterotopic ossification to range-of-motion group: the number of each range-of-motion outcome group sorted by Brooker Class of heterotopic ossification.
	www.vard.org /jour/00/37/4/schafer.htm (2671 words)

	Optimal timing of preoperative radiation for prophylaxis against heterotopic ossification. A rabbit hip model.
		BACKGROUND: In a previous study, we developed a rabbit model of heterotopic ossification and demonstrated that 800 or 1200 cGy of radiation before an operation on the hip significantly decreased postoperative ectopic bone formation compared with that seen after the operation on the non-irradiated, contralateral hip.
		The purpose of this study was to determine the optimal preoperative timing of radiation prophylaxis against heterotopic ossification following hip surgery in this same experimental model.
		Heterotopic ossification was graded according to a modification of the scale of Brooker et al.
	radiotherapy.researchtoday.net /archive/2/2/760.htm (404 words)

	eMedicine - Heterotopic Ossification : Article by Daniel S Moore, MD (Site not responding. Last check: 2007-10-13)
		An elongated mass of mature heterotopic ossification (arrowheads) with peripheral low signal and central fat signal replaces the proximal hamstrings parallel and adjacent to the sciatic nerve (arrow).
		Distal to the mature heterotopic ossification seen on the anteroposterior view (arrowheads) is a subtle area of early mineralization (arrows) consistent with early heterotopic ossification.
		Axial T1-weighted MRI through the proximal mature heterotopic ossification demonstrates a heterogeneous mass with central fat signal anterior to the femoral head, replacing the rectus femoris and a portion of the iliopsoas.
	www.emedicine.com /radio/topic336.htm (5186 words)

	Critical Care \| Full text \| Heterotopic ossification of the knee joint in intensive care unit patients: early diagnosis ...
		Heterotopic ossification (HO) is the formation of bone in soft tissues.
		Heterotopic ossification (HO) is the formation of bone in soft tissues where it is neither needed nor desired [1].
		Ossification in Pellegrini-Stieda disease follows the course of the medial collateral ligament and therefore extends further down than that in HO (b) Parosteal osteosarcoma is a low-grade, bone-forming metaphyseal tumour characterised by thickening of the cortex and a mineralised soft tissue component.
	ccforum.com /content/10/5/R152 (3700 words)

	Other Spinal Cord Injury Health Issues
		Heterotopic ossification (HO) is the development of abnormal bone in soft (non-skeletal) tissue, primarily in the region of the hip and knee joints.
		The primary problem with heterotopic ossification, or HO, is the risk for joint stiffening and fusion.
		Should the hip or knee become fused in a certain position, a surgical release is necessary to allow range of motion to occur.
	www.sci-info-pages.com /other_issues.html (2515 words)

	Acta Ortopédica Brasileira - Heterotopic ossification in patients with traumatic medullar injury: association with ... (Site not responding. Last check: 2007-10-13)
		The purpose of this study was to identify the prevalence of the human leukocyte antigen (HLA) class I and II on the spinal cord injury (SCI) patients and its relation with heterotopic ossification (HO).
		Heterotopic ossification (HO) is a metaplastic biological process with bone neoformation in soft tissues adjacent to large articulations where normally the bone tissue is not found.
		Otfinowski J. Heterotopic induction of osteogenesis in the course of neural injury.
	www.scielo.br /scielo.php?script=sci_arttext&pid=S1413-78522003000200006&lng=es&nrm=iso&tlng=en (2331 words)

	Abstract - Heterotopic ossification in rehabilitation patients who have had internal fixation of an acetabular fracture (Site not responding. Last check: 2007-10-13)
		Heterotopic ossification in rehabilitation patients who have had internal fixation of an acetabular fracture
		Of these, 87 received heterotopic ossification prophylaxis in the form of irradiation or indomethacin; 5 did not receive prophylaxis.
		We present our experience with this patient population, and we discuss the importance of adequate prophylaxis for heterotopic ossification.
	www.vard.org /jour/00/37/4/absschafer.htm (203 words)

	Melorheostosis with heterotopic ossification Information on Healthline (Site not responding. Last check: 2007-10-13)
		The segmental distribution of melorheostosis corresponds most closely to that of the sclerotome, which is defined as an area of the skeleton innervated from a single spinal segment.
		Heterotopic cartilage and bone are occasionally present in the para-articular soft tissues of affected joints,2-7 but are rare in the soft tissues surrounding intact joints without any bone abnormality.
		In the latter situation, it may be difficult to diagnose the heterotopic ossification as a part of melorheostosis.
	www.healthline.com /proquestcontent/melorheostosis-heterotopic-ossification (156 words)

	Prophylaxis with indomethacin for heterotopic ossification after Chiari - Wheeless' Textbook of Orthopaedics
		One hundred patients who had painful dysplasia of the hip were treated with a Chiari osteotomy of the pelvis, and the postoperative radiographs were reviewed for the development of heterotopic ossification.
		Sixty patients did not receive indomethacin postoperatively, and eighteen (30 per cent) had heterotopic ossification of at least class 1; forty patients received indomethacin for two weeks postoperatively, and only three (8 per cent) of them had heterotopic ossification.
		No class-3 or 4 heterotopic ossification was seen in the patients who were given indomethacin.
	www.wheelessonline.com /ortho/prophylaxis_with_indomethacin_for_heterotopic_ossification_after_chiari (168 words)

Try your search on: Qwika (all wikis)