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| | Lipids in Health and Disease | Full text | L-histidine inhibits production of lysophosphatidic acid by the ... |
 | | Site-directed mutagenesis of human ATX established that a specific residue, T210, [7,16] and 3 histidine residues [7,9], corresponding to similar loci in other members of the alkaline phosphatase superfamily, were essential for the motility and enzymatic activities of ATX. |
 | | Histidine therefore inhibits a process that is required for the hydrolysis of both nucleotides and phospholipids. |
 | | While there are known inhibitors of histidine decarboxylase, such as the polyphenols of green tea [32], potent, stable, and non-toxic analogs of histidine would appear to be better therapeutic agents. |
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