
	Where results make sense

Topic: Histone acetyltransferase

Related Topics

Liberalism and centrism in Estonia

Collective nouns for reptiles and amphibians

Tywyn

Lifes Rich Pageant

List of television shows set in Boston

Soprano

Intransitivity

Auburn, Alabama

	Type B Histone Acetyltransferase Hat1p Participates in Telomeric Silencing -- Kelly et al. 20 (19): 7051 -- Molecular ...
		redundancy in the histones that obviate the acetylation of histone
		histone H4 tail lysines are mutated to arginine (10).
		A novel histone acetyltransferase is an integral subunit of elongating RNA polymerase II holoenzyme.
	mcb.asm.org /cgi/content/full/20/19/7051 (6146 words)

	Interactive Fly, Drosophila
		Histones are subsequently modified again in a way that reflects the activation status of the gene with which they associate.
		Histone acetyltransferase is subsequently removed and CAF1 components are substituted, transferring p48 and its histones from the cytoplasm to the nucleus, where histones are assembled into nucleosomes at the DNA replication fork.
		Given that WD repeat proteins related to p55 are associated with histone deacetylase and histone acetyltransferase, these findings suggest that p55 and its homologs may function as a common platform for the assembly of protein complexes involved in chromatin metabolism (Martinez-Balbas, 1998).
	www.sdbonline.org /fly/polycomb/caf1-1.htm (1008 words)

	OhioLINK ETD: Ai, Xi
		Histone acetylation plays an important role in the assembly and modulation of chromatin structure.
		Two main types of Histone AcetylTransferase (HAT), HAT-A and HAT- B, are responsible for the acetylation of histones.
		The functional significance of the association of Hif1p with the Hat1p/Hat2p complex is confirmed by the observation that hif1ƒ´ and hat1ƒ´ strains display similar defects in telomeric silencing and DNA double strand break repair.
	rave.ohiolink.edu /etdc/view?acc_num=osu1085509452 (374 words)

	Pfam 19.0 : Acetyltransf_1 (Site not responding. Last check: 2007-11-06)
		Histone acetylation is carried out by a class of enzymes known as histone acetyltransferases (HATs), which catalyze the transfer of an acetyl group from acetyl-CoA to the lysine E-amino groups on the N-terminal tails of histonesPUBMED:12801725.
		Early indication that HATs were involved in transcription came from the observation that in actively transcribed regions of chromatin, histones tend to be hyperacetylated, whereas in transcriptionally silent regions histones are hypoacetylated.
		The crystal structure of the yeast histone acetyltransferase Hat1-acetyl coenzyme A (AcCoA) shows that Hat1 has an elongated, curved structure, and the AcCoA molecule is bound in a cleft on the concave surface of the protein, marking the active site of the enzyme.
	pfam.wustl.edu /cgi-bin/getdesc?name=Acetyltransf_1 (348 words)

	Jerry Workman - Stowers Institute for Medical Research
		For example, the amino-terminal tail domains of the core histone proteins are sights of numerous post-translational modifications.
		While histone acetylation is most often associated with gene activation, it also plays important roles in gene silencing.
		Sas4 and Sas5 are required for the histone acetyltransferase activity of Sas2 in the SAS complex.
	www.stowers-institute.org /labs/workmanLab.asp (2585 words)

	Human protein: Q92794 - Histone acetyltransferase MYST3 (EC ) (EC
		histone acetyltransferase which may act as a transcriptional coactivator for runx1 and runx2.
		Upstream genomic sequence for MYST histone acetyltransferase (monocytic leukemia) 3
		The monocytic leukemia zinc finger protein MOZ is a histone acetyltransferase.
	harvester.embl.de /harvester/Q927/Q92794.htm (1185 words)

	Myst3 - MYST histone acetyltransferase (monocytic leukemia) 3 (Site not responding. Last check: 2007-11-06)
		Exons 2-13 of the ASXL2 gene are fused to exons 1-14 of the MYST3 gene in a case of therapy-related myelodysplastic syndrome due to t(2;8)(p23.3;p11.2).
		It has been reported that AML1 is capable of interaction with histone acetyl transferases (CBP, p300, and MOZ) and with component of the histone deacetylase complex (Sin3), and that the interaction with these coregulators affects the strength of AML1 in promoter regulation.
		Myst3 is a homologue of MYST3 (MYST histone acetyltransferase (monocytic leukemia) 3) from Homo sapiens.
	www.ihop-net.org /UniPub/iHOP/gg/155541.html (159 words)

	[No title]
		The transcriptional coactivators p300 and CBP are histone acetyltransferases.
		Histone acetyltransferase activity and interaction with ADA2 are critical for GCN5 function in vivo.
		Histone acetyltransferase activity is conserved between yeast and human GCN5 and is required for complementation of growth and transcriptional activation.
	www.cstone.net /~jrb7q/hatrefs.html (733 words)

	Histone methyltransferase - Wikipedia, the free encyclopedia
		Histone methyltransferases (HMT) are enzymes, histone-lysine N-methyltransferase and histone-arginine N-methyltransferase, which catalyze the transfer of one to three methyl groups from the cofactor s-adenosylmethionine to lysine and arginine residues of histone proteins.
		These proteins often contain an SET (Su(var)3-9, Enhancer of Zeste, Trithorax) domain, however the recently discovered HMT Dot1 lacks the characteristic SET domain.
		Methylated histones bind DNA more tightly, which inhibits transcription.
	en.wikipedia.org /wiki/Histone_methyltransferase (100 words)

	p300/CBP-associated Factor Histone Acetyltransferase Processing of a Peptide Substrate. KINETIC ANALYSIS OF THE ...
		subset of the histone acetyltransferases and have significant
		Acetyltransferase assays and data fitting were performed as described under "Materials and Methods." The catalytic parameters are displayed in Table II.
		Acetyltransferase assays and data fitting were performed as described under "Materials and Methods." The inhibition parameters are displayed in Table III.
	www.jbc.org /cgi/content/full/275/29/21953 (4511 words)

	ESA1 is a histone acetyltransferase that is essential for growth in yeast -- Smith et al. 95 (7): 3561 -- Proceedings ...
		ESA1 is a histone acetyltransferase that is essential for growth in yeast -- Smith et al.
		that acetylate histones H3 and H2B in chromatin (33).
		histones H2A and H4 in the context of chromatin.
	www.pnas.org /cgi/content/full/95/7/3561 (4622 words)

	Deregulation of Polyamine Biosynthesis Alters Intrinsic Histone Acetyltransferase and Deacetylase Activities in Murine ...
		Histones from parallel dishes of K6/ODC keratinocytes treated with DFMO to maintain ODC activity at normal levels are also shown.
		Filters were reprobed with antibodies against histone H3 and H4 for normalization of the total amounts of histone protein loaded in each lane of the gels.
		Estepa I., Pestana A. Activation by polyamines of the acetylation of endogenous histones in isolated chromatin and nuclei from Artemia.
	cancerres.aacrjournals.org /cgi/content/full/62/1/67 (6594 words)

	A Targeted Histone Acetyltransferase Can Create a Sizable Region of Hyperacetylated Chromatin and Counteract the ...
		that preferentially acetylates histone H4 whereas Gcn5p is a
		A tethered HAT generates a zone of histone hyperacetylation on both sides (shaded arrows) and blocks the spread of transcriptional silencing.
		, M., and C., 1998 Histone acetyltransferase activity of yeast Gcn5p is required for the activation of target genes in vivo.
	www.genetics.org /cgi/content/full/165/1/115 (6767 words)

	Esa1p Is an Essential Histone Acetyltransferase Required for Cell Cycle Progression -- Clarke et al. 19 (4): 2515 -- ...
		Histones are dynamically modified during chromatin assembly, as specific transcriptional patterns are established, and during
		of an acetylated isoform of histone H4 in vivo.
		Adachi, N., Kimura, A., Horikoshi, M. A Conserved Motif Common to the Histone Acetyltransferase Esa1 and the Histone Deacetylase Rpd3.
	mcb.asm.org /cgi/content/abstract/19/4/2515 (1560 words)

	Histone acetyltransferase activity of yeast Gcn5p is required for the activation of target genes in vivo -- Kuo et al. ...
		Histone acetyltransferase activity of yeast Gcn5p is required for the activation of target genes in vivo -- Kuo et al.
		Histone acetyltransferase activity of yeast Gcn5p is required for the activation of target genes in vivo
		Histones from several mutants that function nearly normally in our in vivo assays were also examined; these histones all show
	www.genesdev.org /cgi/content/full/12/5/627 (6277 words)

	The ATM-related domain of TRRAP is required for histone acetyltransferase recruitment and Myc-dependent oncogenesis -- ...
		Ogryzko, V.V., Schiltz, R.L., Russanova, V., Howard, B.H., and Nakatani, Y. The transcriptional coactivators p300 and CBP are histone acetyltransferases.
		Sterner, D.E. and Berger, S.L. Acetylation of histones and transcription-related factors.
		Wang, L., Mizzen, C., Ying, R., Candau, R., Barlev, N., Brownell, J., Allis, C.D., and Berger, S. Histone acetyltransferase activity is conserved between yeast and human GCN5 and required for complementation of growth and transcriptional activation.
	www.genesdev.org /cgi/content/full/15/13/1619 (3752 words)

	Increased Histone Acetyltransferase and Lysine Acetyltransferase Activity and Biphasic Activation of the ERK/RSK ... (Site not responding. Last check: 2007-11-06)
		Increased Histone Acetyltransferase and Lysine Acetyltransferase Activity and Biphasic Activation of the ERK/RSK Cascade in Insular Cortex During Novel Taste Learning
		acetylation of lysine residues on histones by histone acetyltransferases
		the lysine acetylation of a 42 kDa lysine acetyltransferase substrate,
	www.jneurosci.org /cgi/content/abstract/21/10/3383 (447 words)

	The BRCA2 is a histone acetyltransferase (Site not responding. Last check: 2007-11-06)
		Forty-five-amino acid region encoded by exon 3 of BRCA2 was shown to have transcriptional activation function.
		Recent studies of the several enzymes involved in acetylation and deacetylation of histone residues have revealed a possible relationship between gene transcriptional activation and histone acetylation.
		Since BRCA2 appear to function as a transcriptional factor, we have tested for Histone acetyl transferase (HAT) activity of BRCA2.
	www.meb.uni-bonn.de /cgi-bin/mycite?ExtRef=ICDB/98281136 (166 words)

	Acetylation of Histones and Transcription-Related Factors -- Sterner and Berger 64 (2): 435 -- Microbiology and ...
		Pair of Unusual GCN5 Histone Acetyltransferases and ADA2 Homologues in the Protozoan Parasite Toxoplasma gondii.
		Ferguson, M., Henry, P. A., Currie, R. Histone deacetylase inhibition is associated with transcriptional repression of the Hmga2 gene.
		Makowski, A. M., Dutnall, R. N., Annunziato, A. Effects of Acetylation of Histone H4 at Lysines 8 and 16 on Activity of the Hat1 Histone Acetyltransferase.
	mmbr.asm.org /cgi/content/abstract/64/2/435 (5243 words)

	The Histone Acetyltransferase Activity of Human GCN5 and PCAF Is Stabilized by Coenzymes -- Herrera et al. 272 (43): ...
		The Histone Acetyltransferase Activity of Human GCN5 and PCAF Is Stabilized by Coenzymes -- Herrera et al.
		The Histone Acetyltransferase Activity of Human GCN5 and PCAF Is Stabilized by Coenzymes
		Histone H1 Is a Specific Repressor of Core Histone Acetylation in Chromatin
	www.jbc.org /cgi/content/abstract/272/43/27253 (717 words)

	Histone Acetyltransferase Deacetylase
		Histone acetyltransferases (HATs) play important roles in gene transcription, differentiation, and cellular proliferation.
		Inhibition of histone deacetylases (HDACs) has been reported to modulate transcription and to induce apoptosis or differentiation in cancer cells.
		This convenient microplate assay kit provides for the rapid (~ 1-2 hr) colorimetric assessment of HAT activity.
	www.oxfordbiomed.com /ca02hat.html (163 words)

	Novel Substrate Specificity of the Histone Acetyltransferase Activity of HIV-1-Tat Interactive Protein Tip60 -- ...
		the histone acetyltransferase activity of the evolutionarily conserved
		First we tested the histone acetyltransferase activity of Tip60C.
		We have directly proven that Tip60 is a nuclear histone acetyltransferase with a novel substrate specificity.
	www.jbc.org /cgi/content/full/272/49/30595 (3954 words)

	A single histone acetyltransferase from Tetrahymena macronuclei catalyzes deposition-related acetylation of free ...
		A single histone acetyltransferase from Tetrahymena macronuclei catalyzes deposition-related acetylation of free histones and transcription-related acetylation of nucleosomal histones -- Chicoine et al.
		A single histone acetyltransferase from Tetrahymena macronuclei catalyzes deposition-related acetylation of free histones and transcription-related acetylation of nucleosomal histones
		substrate, all four core histones are acetylated by the same extract, and
	www.jcb.org /cgi/content/abstract/105/1/127 (271 words)

	Glucose Regulation of Insulin Gene Expression Requires the Recruitment of p300 by the {beta}-Cell-Specific ...
		The histone acetylation levels associated with the rat insulin I gene promoter were analyzed in isolated rat islets incubated with 3 or 20 m
		A, The association of the histone acetyltransferase p300 with the mouse insulin I or pklr (L-type pruvate kinase) promoter as control was analyzed by ChIP assay in MIN6 cells incubated with 3 or 30 m
		for hyperacetylation of histone H4 in response to glucose.
	mend.endojournals.org /cgi/content/full/18/9/2279 (6328 words)

	Novel substrate specificity of the histone acetyltransferase activity of HIV-1-Tat interactive protein Tip60.
		We demonstrate here direct biochemical evidence that this domain of Tip60 has histone acetyltransferase activity.
		This substrate specificity has not been observed among histone acetyltransferases analyzed to date.
		These results indicate that Tip60 is a histone acetyltransferase with a novel property, suggesting that Tip60 and its related factors may introduce a distinct alteration on chromatin.
	www.aegis.com /aidsline/1998/mar/M9830979.html (335 words)

	Snf1--a Histone Kinase That Works in Concert with the Histone Acetyltransferase Gcn5 to Regulate Transcription -- Lo et ...
		Snf1--a Histone Kinase That Works in Concert with the Histone Acetyltransferase Gcn5 to Regulate Transcription -- Lo et al.
		Lane 1, mixture of free core histones; lane 2, histone H3 1-26 residue peptide; lane 3, histone H3 1-26 residue Ser-10-phosphorylated; lane 4, histone H3 1-26 residue Ser-10-phosphorylated/Lys-14-acetylated; lane 5, histone H3 1-26 residue Lys-14-acetylated; lane 6, full-length histone H3.
		Each peptide or histone sample was spotted onto membrane in serial dilution (0.5-500 ng).
	www.sciencemag.org /cgi/content/full/293/5532/1142/DC1 (248 words)

	Histone acetyltransferase activity of yeast Gcn5p is required for the activation of target genes in vivo -- Kuo et al. ...
		Domain-Wide Displacement of Histones by Activated Heat Shock Factor Occurs Independently of Swi/Snf and Is Not Correlated with RNA Polymerase II Density
		Components of the SAGA Histone Acetyltransferase Complex Are Required for Repressed Transcription of ARG1 in Rich Medium
		Dynamics of global histone acetylation and deacetylation in vivo: rapid restoration of normal histone acetylation status upon removal of activators and repressors
	www.genesdev.org /cgi/content/abstract/12/5/627 (2564 words)

	Polyglutamine-expanded ataxin-7 inhibits STAGA histone acetyltransferase activity to produce retinal degeneration -- ...
		Polyglutamine-expanded ataxin-7 inhibits STAGA histone acetyltransferase activity to produce retinal degeneration -- Palhan et al.
		Articles by Palhan, V. Articles by Roeder, R. Polyglutamine-expanded ataxin-7 inhibits STAGA histone acetyltransferase activity to produce retinal degeneration
		GCN5 histone acetyltransferase component of STAGA, and mediates
	www.pnas.org /cgi/content/abstract/102/24/8472 (447 words)

Try your search on: Qwika (all wikis)